tolbutamide has been researched along with Cushing Syndrome in 8 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In five patients with islet cell tumors and fasting hypoglycemia, basal proinsulin-like component ranged from 26 to 79% of the total immunoreactive insulin." | 1.25 | Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors. ( Gorden, P; Roth, J; Sherman, B, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| EYMONTT, MJ | 1 |
| GWINUP, G | 1 |
| KRUGER, FA | 1 |
| MAYNARD, DE | 1 |
| HAMWI, GJ | 1 |
| BOTTERMANN, P | 1 |
| SCHWARZ, K | 1 |
| KOPETZ, K | 1 |
| Gorden, P | 1 |
| Sherman, B | 1 |
| Roth, J | 1 |
| Strauch, G | 1 |
| Modigliani, E | 1 |
| Luton, JP | 1 |
| Bricaire, H | 1 |
| Crepaldi, G | 2 |
| Tiengo, A | 2 |
| Muggeo, M | 2 |
| Trisotto, A | 2 |
| Federspil, G | 2 |
| Scandellari, C | 1 |
| Kahl, GF | 1 |
| Avogaro, P | 1 |
| Enzi, G | 1 |
| Camanni, F | 1 |
| Massara, F | 1 |
| Molinatti, GM | 1 |
8 other studies available for tolbutamide and Cushing Syndrome
| Article | Year |
|---|---|
CUSHING'S SYNDROME WITH HYPOGLYCEMIA CAUSED BY ADRENOCORTICAL CARCINOMA.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Aldos | 1965 |
[ON THE BEHAVIOR OF THE INSULIN-LIKE ACTIVITY OF THE BLOOD SERUM IN ADIPOSITY].
Topics: Adiposity; Cushing Syndrome; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hyperinsulinism; Ins | 1965 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; | 1971 |
Partial somatotrophin insufficiency in Cushing's syndrome.
Topics: Adult; Arginine; Cushing Syndrome; Female; Glucose Tolerance Test; Growth Hormone; Humans; Hypoglyce | 1969 |
[Primary and secondary hyperinsulinism].
Topics: Acromegaly; Cushing Syndrome; Diabetes Complications; Glucagon; Glucose Tolerance Test; Humans; Hype | 1970 |
[Changes in the velocity of drug catabolism and their importance in drug therapy].
Topics: Administration, Oral; Age Factors; Alcohols; Anticoagulants; Anticonvulsants; Carcinogens; Contracep | 1971 |
[The insulinemic response after oral administration of glucose and after intravenous administration of tolbutamide in patients with Cushin's syndrome].
Topics: Blood Glucose; Cushing Syndrome; Diabetes Mellitus; Fatty Acids; Glucose; Glucose Tolerance Test; Hu | 1967 |
[The tolbutamide test in Cusing's syndrome. Preliminary observations].
Topics: Adolescent; Adult; Animals; Child; Cushing Syndrome; Female; Glucose Tolerance Test; Humans; Male; M | 1966 |