tolbutamide has been researched along with Coronary Disease in 30 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to determine whether activation of adenosine triphosphate (ATP)-sensitive K+ channels exclusively explains the hypoxia- and ischaemia-induced action potential shortening, effects of tolbutamide and glibenclamide on changes in action potential duration (APD) during hypoxia, metabolic blockade or experimental ischaemia were examined in guinea-pig and canine isolated myocardium by standard microelectrode techniques." | 3.68 | Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium. ( Kanno, M; Nakaya, H; Takeda, Y; Tohse, N, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (90.00) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SCHWARTZ, W | 1 |
| FEARNLEY, GR | 4 |
| CHAKRABARTI, R | 3 |
| Itagaki, T | 1 |
| Schaffer, SW | 2 |
| Poole, CG | 1 |
| Lampson, WG | 2 |
| Kramer, JH | 2 |
| Miettinen, OS | 1 |
| Cook, EF | 1 |
| Luccioni, R | 1 |
| Vague, P | 1 |
| Balansard, P | 1 |
| Vague, J | 1 |
| Simonin, R | 1 |
| Gérard, R | 1 |
| Bunnag, SC | 1 |
| Bunnag, S | 1 |
| Khaletskiĭ, ME | 2 |
| Vaisrub, S | 1 |
| Moss, JM | 1 |
| Venkatesh, N | 1 |
| Lamp, ST | 1 |
| Weiss, JN | 1 |
| Nakaya, H | 1 |
| Takeda, Y | 1 |
| Tohse, N | 1 |
| Kanno, M | 1 |
| Gasser, RN | 1 |
| Vaughan-Jones, RD | 1 |
| Wolleben, CD | 1 |
| Sanguinetti, MC | 1 |
| Siegl, PK | 1 |
| Nikkilä, EA | 1 |
| Miettinen, TA | 1 |
| Vesenne, MR | 1 |
| Pelkonen, R | 1 |
| Turtle, JR | 1 |
| Marble, A | 2 |
| Popescu, P | 1 |
| Anghel, S | 1 |
| Idu, S | 1 |
| Mihai, N | 1 |
| Moldovan, T | 1 |
| Mihail, A | 1 |
| Ettinger, PO | 1 |
| Oldewurtel, HA | 1 |
| Sethi, V | 1 |
| Regan, TJ | 1 |
| Hocking, ED | 1 |
| Evans, J | 1 |
| Kashyap, ML | 1 |
| Magill, F | 1 |
| Rojas, L | 1 |
| Hoffman, MM | 1 |
| Cristol, R | 1 |
| Cottet, J | 1 |
| Cloarec, M | 1 |
| Parr, F | 1 |
| Lenti, G | 1 |
| Pellegrini, A | 1 |
| Pagano, G | 1 |
| Porrazzo, G | 1 |
| Brotzu, M | 1 |
2 reviews available for tolbutamide and Coronary Disease
| Article | Year |
|---|---|
Recent developments in the management of diabetes mellitus.
Topics: Animals; Australia; Coronary Disease; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropathie | 1974 |
Glibenclamide, a new sulphonylurea: whither oral hypoglycaemic agents?
Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Carbohydrates; Child; Coronary Disease; Diab | 1971 |
28 other studies available for tolbutamide and Coronary Disease
| Article | Year |
|---|---|
MEBUTAMATE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION.
Topics: Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure Determination; Carbamates; | 1964 |
THE PHARMACOLOGICAL ENHANCEMENT OF BLOOD FIBRINOLYTIC ACTIVITY WITH SPECIAL REFERENCE TO PHENFORMIN.
Topics: Anabolic Agents; Anticoagulants; Arteriosclerosis Obliterans; Chlorpropamide; Coronary Disease; Fibr | 1964 |
PHARMACOLOGICAL ENCHANCEMENT OF FIBRINOLYTIC ACTIVITY OF BLOOD.
Topics: Adrenal Cortex Hormones; Anabolic Agents; Arteriosclerosis; Chlorpropamide; Coronary Disease; Fibrin | 1964 |
[Relationship between antihyperglycemic drugs and myocardial infarction in the aged--a retrospective study].
Topics: Aged; Blood Glucose; Coronary Disease; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Ma | 1984 |
Effect of tolbutamide on the mechanical function of the isolated rat heart subjected to global ischemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coronary Disease; H | 1981 |
Confounding: essence and detection.
Topics: Biometry; Coronary Disease; Epidemiologic Methods; Female; Follow-Up Studies; Humans; Lung Neoplasms | 1981 |
[Abnormalities of insulin secretion in coronary patients. Apropos of 67 cases].
Topics: Adult; Age Factors; Aged; Coronary Disease; Female; Glucose Tolerance Test; Humans; Hyperglycemia; H | 1977 |
Tolbutamide, postnatal neogenesis of the islets of Langerhans and myocardial insufficiency: a case report.
Topics: Aged; Coronary Disease; Diabetes Complications; Female; Heart Failure; Humans; Hyperplasia; Islets o | 1976 |
[Necessity of active treatment of latent forms of diabetes mellitus in patients with arteriosclerosis].
Topics: Adolescent; Adult; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Humans; Male; Middle | 1976 |
Editorial: Platelet aggregation.
Topics: Adenosine Diphosphate; Aspirin; Cerebrovascular Disorders; Coronary Disease; Glucose; Humans; Hyperl | 1975 |
Medical guest editorial: The oral diabetic drug controversy.
Topics: Coronary Disease; Diabetes Mellitus; Humans; Tolbutamide; United States; United States Food and Drug | 1975 |
Why the conclusions of the University Group Diabetes Project are incorrect.
Topics: Coronary Disease; Diabetes Complications; Diabetes Mellitus; Evaluation Studies as Topic; Female; Hu | 1975 |
Sulfonylureas, ATP-sensitive K+ channels, and cellular K+ loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Binding Sites; Coronary Disease; Female; Glyburi | 1991 |
Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Fe | 1991 |
Mechanism of potassium efflux and action potential shortening during ischaemia in isolated mammalian cardiac muscle.
Topics: Action Potentials; Animals; Bumetanide; Chlorides; Coronary Disease; Coumaric Acids; Deoxyglucose; F | 1990 |
Influence of ATP-sensitive potassium channel modulators on ischemia-induced fibrillation in isolated rat hearts.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Coronar | 1989 |
Effect of tolbutamide on myocardial energy metabolism of the ischemic heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Energy Metabolism; Glucose; | 1985 |
Plasma-insulin in coronary heart-disease: response to oral and intravenous glucose and to tolbutamide.
Topics: Adolescent; Adult; Aged; Blood; Cholesterol; Coronary Disease; Fatty Acids; Female; Glucose Toleranc | 1965 |
Vascular disease in diabetes and the effect of oral antidiabetic agents.
Topics: Arteriosclerosis; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Diabetes Mel | 1973 |
[On the intravenous tolbutamide test (ivTT) in patients with coronary disease. (Glucide-lipid metabolic relationships)].
Topics: Adult; Aged; Carbohydrate Metabolism; Coronary Disease; Diabetic Angiopathies; Female; Humans; Hyper | 1974 |
[Occult forms of diabetes mellitus in atherosclerosis].
Topics: Adult; Arteriosclerosis; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diet Therapy; | 1972 |
Glucose intolerance in cardiac patients without myocardial ischemia and its relation tto cardiac output.
Topics: Adolescent; Adult; Aged; Cardiac Catheterization; Cardiac Output; Cardiomyopathies; Coronary Disease | 1971 |
Fibrinolytic effect of biguanides.
Topics: Adult; Aged; Angina Pectoris; Arteriosclerosis Obliterans; Biguanides; Chlorpropamide; Coronary Dise | 1968 |
Insulin and non-esterified fatty acid metabolism in asymptomatic diabetics and atherosclerotic subjects.
Topics: Arteriosclerosis; Blood Glucose; Coronary Disease; Diabetes Mellitus; Fatty Acids, Nonesterified; Gl | 1970 |
[Study of glucose regulation by an intravenous tolbutamide test in coronar insufficiency].
Topics: Adult; Age Factors; Arteriosclerosis; Blood Glucose; Body Weight; Cholesterol; Coronary Disease; Dia | 1970 |
[Astonin-H effect on blood circulation and metabolism].
Topics: Blood Circulation; Blood Pressure; Blood Vessels; Carbohydrate Metabolism; Coronary Disease; Fludroc | 1971 |
Pharmacological fibrinolysis.
Topics: Aged; Androsterone; Anticholesteremic Agents; Butyrates; Chlorpropamide; Coronary Disease; Ethylestr | 1969 |
[Familial aspects of the relations between diabetes mellitus and cardiovascular diseases. Clinico-experimental research].
Topics: Adult; Coronary Disease; Cryoglobulins; Diabetes Complications; Diabetes Mellitus; Female; Glucose T | 1966 |