tolbutamide has been researched along with Constitutional Liver Dysfunction in 1 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pathophysiology of Gilbert's syndrome was studied by investigating the metabolism of the drug tolbutamide, which is metabolised by the liver but does not undergo glucuronidation." | 1.26 | Alteration of drug metabolism in Gilbert's syndrome. ( Carulli, N; Ferrari, A; Manenti, F; Mauro, E; Ponz de Leon, M, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carulli, N | 1 |
| Ponz de Leon, M | 1 |
| Mauro, E | 1 |
| Manenti, F | 1 |
| Ferrari, A | 1 |
1 other study available for tolbutamide and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
Alteration of drug metabolism in Gilbert's syndrome.
Topics: Adult; Animals; Cytoplasm; Gilbert Disease; Half-Life; Humans; Hyperbilirubinemia, Hereditary; Liver | 1976 |