tolbutamide has been researched along with Congenital Hyperinsulinism in 3 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Congenital Hyperinsulinism: A familial, nontransient HYPOGLYCEMIA with defects in negative feedback of GLUCOSE-regulated INSULIN release. Clinical phenotypes include HYPOGLYCEMIA; HYPERINSULINEMIA; SEIZURES; COMA; and often large BIRTH WEIGHT. Several sub-types exist with the most common, type 1, associated with mutations on an ATP-BINDING CASSETTE TRANSPORTERS (subfamily C, member 8).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Infants with congenital hyperinsulinism often require pancreatectomy." | 1.32 | Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation. ( Adzick, NS; Bhatia, P; Ganguly, A; Kaye, R; MacMullen, C; Ruchelli, E; Stanley, CA; Steinkrauss, L; Suchi, M; Thornton, PS; Underwood, P; Wanner, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Law, NC | 1 |
| Marinelli, I | 1 |
| Bertram, R | 1 |
| Corbin, KL | 1 |
| Schildmeyer, C | 1 |
| Nunemaker, CS | 1 |
| Henquin, JC | 1 |
| Nenquin, M | 1 |
| Sempoux, C | 1 |
| Guiot, Y | 1 |
| Bellanné-Chantelot, C | 1 |
| Otonkoski, T | 1 |
| de Lonlay, P | 1 |
| Nihoul-Fékété, C | 1 |
| Rahier, J | 1 |
| Stanley, CA | 1 |
| Thornton, PS | 1 |
| Ganguly, A | 1 |
| MacMullen, C | 1 |
| Underwood, P | 1 |
| Bhatia, P | 1 |
| Steinkrauss, L | 1 |
| Wanner, L | 1 |
| Kaye, R | 1 |
| Ruchelli, E | 1 |
| Suchi, M | 1 |
| Adzick, NS | 1 |
3 other studies available for tolbutamide and Congenital Hyperinsulinism
| Article | Year |
|---|---|
Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro.
Topics: Adaptation, Physiological; Animals; Calcium Signaling; Cell Membrane; Congenital Hyperinsulinism; Hu | 2020 |
In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.
Topics: ATP-Binding Cassette Transporters; Congenital Hyperinsulinism; Cyclin-Dependent Kinase Inhibitor p57 | 2011 |
Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation.
Topics: Arteries; ATP-Binding Cassette Transporters; Calcium; Congenital Hyperinsulinism; DNA Mutational Ana | 2004 |