tolbutamide has been researched along with Chronic Disease in 41 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " over forty minutes) on plasma pancreatic glucagon-like immunoreactivity (PGLI), serum insulin, and blood glucose were studied in six patients with chronic pancreatitis and six matched controls." | 7.65 | Immunoreactive glucagon responses to intravenous tolbutamide in chronic pancreatitis. ( Jackson, WP; Kalk, WJ; Leller, P; Paul, M; Vinik, AI, 1975) |
| " over forty minutes) on plasma pancreatic glucagon-like immunoreactivity (PGLI), serum insulin, and blood glucose were studied in six patients with chronic pancreatitis and six matched controls." | 3.65 | Immunoreactive glucagon responses to intravenous tolbutamide in chronic pancreatitis. ( Jackson, WP; Kalk, WJ; Leller, P; Paul, M; Vinik, AI, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (97.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, W | 1 |
| Carreño, FR | 1 |
| Cunningham, JT | 1 |
| Mifflin, SW | 1 |
| Ventrucci, M | 1 |
| Gullo, L | 1 |
| Capelli, M | 1 |
| Platé, L | 1 |
| Bolondi, L | 1 |
| Fontana, G | 1 |
| Andreev, D | 2 |
| Turkolev, N | 1 |
| Prescott, LF | 1 |
| Forrest, JA | 1 |
| Adjepon-Yamoah, KK | 1 |
| Finlayson, ND | 1 |
| Streda, M | 1 |
| Vague, P | 2 |
| Ramahandridona, G | 2 |
| Vialettes, B | 1 |
| Mütting, D | 1 |
| Kaufmann, M | 1 |
| Pampulov, L | 1 |
| Sancilio, LF | 1 |
| Reese, DL | 1 |
| Cheung, S | 1 |
| Alphin, RS | 1 |
| Thiessen, JJ | 1 |
| Sellers, EM | 1 |
| Denbeigh, P | 1 |
| Dolman, L | 1 |
| Dorchy, H | 1 |
| Ooms, H | 1 |
| Loeb, H | 1 |
| Kalk, WJ | 2 |
| Vinik, AI | 3 |
| Paul, M | 1 |
| Leller, P | 1 |
| Jackson, WP | 3 |
| Borisova, AM | 2 |
| Koev, D | 2 |
| Kirilov, G | 2 |
| Kostelnik, ME | 1 |
| Iber, FL | 2 |
| Ciba, T | 1 |
| Sowa, J | 1 |
| Gerolami, A | 1 |
| Woolf, IL | 1 |
| B oyes, BE | 1 |
| Leeming, JT | 1 |
| Dymock, IW | 1 |
| Grabner, W | 3 |
| Phillip, J | 2 |
| Strigl, P | 1 |
| Bank, S | 2 |
| Keller, P | 2 |
| Mayer, A | 1 |
| Daniel, U | 1 |
| Matzkies, F | 1 |
| Mehnert, H | 1 |
| Held, H | 1 |
| Eisert, R | 1 |
| von Oldershausen, HF | 1 |
| Gundert-Remy, U | 1 |
| Marquardt, R | 1 |
| Andritsch, F | 1 |
| Weber, E | 1 |
| Liberman, B | 1 |
| Wajchenberg, BL | 1 |
| Bevilaqua, RG | 1 |
| Ellenbogen, G | 1 |
| Goffi, FS | 1 |
| Sauer, H | 1 |
| Böninger, C | 1 |
| Bergner, D | 1 |
| Scharrer, H | 1 |
| Sommer, B | 1 |
| Berg, G | 1 |
| Shah, MN | 1 |
| Clancy, BA | 1 |
| Lao, B | 1 |
| Orlowska, K | 1 |
| Hirayama, C | 1 |
| Sotaniemi, E | 1 |
| Arvela, P | 1 |
| Huhti, E | 1 |
| Koivisto, O | 1 |
| Zastrow, R | 1 |
| Schimmelpfennig, W | 1 |
| Wagner, K | 1 |
| Schneider, G | 1 |
| Theuer, D | 1 |
| Schimmelpfennig, R | 1 |
| Zimmermann, HB | 1 |
| Hecht, A | 1 |
| Fourlinnie, JC | 1 |
| Bedoret, JM | 1 |
| Duc-Cuvelier, MF | 1 |
| Caridroit, M | 1 |
| Fontan, M | 1 |
| Linquette, M | 1 |
| Schlote, HW | 1 |
| Marré, E | 1 |
| Heully, F | 1 |
| Laurent, J | 1 |
| Giry, D | 1 |
| Debry, G | 1 |
| Sperling, M | 1 |
| Drash, A | 1 |
| Joffe, BI | 1 |
| Reissert, K | 1 |
| Rudas, B | 1 |
| Bergmann, M | 1 |
| Vetter, K | 1 |
| Kettler, LH | 1 |
| Kaschube, I | 1 |
| Lüder, W | 1 |
2 reviews available for tolbutamide and Chronic Disease
| Article | Year |
|---|---|
Drug metabolism in liver disease.
Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; H | 1975 |
Glucose tolerance tests in the clinical picture of chronic liver diseases.
Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Body Weight | 1975 |
2 trials available for tolbutamide and Chronic Disease
| Article | Year |
|---|---|
[Therapeutic effect of glibenclamide contrasted with other oral antidiabetic agents].
Topics: Administration, Oral; Adult; Biguanides; Chlorpropamide; Chronic Disease; Clinical Trials as Topic; | 1975 |
[Drug therapy of chronic inflammatory liver diseases].
Topics: Aldosterone; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Nandrolone; Predni | 1966 |
37 other studies available for tolbutamide and Chronic Disease
| Article | Year |
|---|---|
Chronic sustained and intermittent hypoxia reduce function of ATP-sensitive potassium channels in nucleus of the solitary tract.
Topics: Animals; Antihypertensive Agents; Blotting, Western; Carotid Body; Chronic Disease; Diazoxide; Elect | 2008 |
[Combined stimulation of the beta cells in chronic pancreatitis].
Topics: Adult; Blood Glucose; Chronic Disease; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets | 1979 |
[Pathogenesis of diabetes in adulthood. II. The nature of the insulin secretory defect].
Topics: Adult; Age Factors; Blood Glucose; Chronic Disease; Diabetes Mellitus; Female; Glucose Tolerance Tes | 1978 |
[A method of studying insulin secretion in humans: the glucose stimulation test, followed by tolbutamide].
Topics: Age Factors; Blood Glucose; Body Weight; Chronic Disease; Diabetes Mellitus; Dose-Response Relations | 1976 |
[Disorders of glucose tolerance in 2600 histologically confirmed acute and chronic liver patients (author's transl)].
Topics: Acute Disease; Administration, Oral; Alcoholism; Chronic Disease; Diabetes Complications; Fatty Live | 1975 |
AHR-5850: a potent anti-inflammatory compound.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Benzophenones; Blood Glucose; Cats; Chronic Diseas | 1977 |
Plasma protein binding of diazepam and tolbutamide in chronic alcoholics.
Topics: Alcoholism; Blood Proteins; Chemical and Drug Induced Liver Injury; Chronic Disease; Diazepam; Femal | 1976 |
Permanent neonatal diabetes mellitus: a case report with plasma insulin studies.
Topics: Blood Glucose; Chronic Disease; Diabetes Mellitus; Drug Tolerance; Glucagon; Glucose Tolerance Test; | 1975 |
Immunoreactive glucagon responses to intravenous tolbutamide in chronic pancreatitis.
Topics: Adult; Alcoholism; Blood Glucose; Chronic Disease; Glucagon; Humans; Insulin; Male; Middle Aged; Pan | 1975 |
[An improvement in insulin efficacy in patients with type-1 diabetes mellitus following treatment using an insulin infusion pump].
Topics: Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Drug Evaluation; Humans; Insul | 1989 |
[Factors affecting stability in the course of insulin-dependent diabetes mellitus].
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Chronic Disease; Circadian Rhythm; Diabetes Mellitus, T | 1989 |
Correlation of alcohol and tolbutamide blood clearance rates with microsomal alcohol-metabolizing enzyme activity.
Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Biopsy; Chronic Disease; Ethanol; Half-Life; Humans; Inj | 1973 |
[Coefficient of glucose assimilation and blood sugar curves following administration of tolbutamide to patients with chronic hepatitis].
Topics: Adolescent; Adult; Blood Glucose; Chronic Disease; Glucose; Hepatitis; Humans; Injections, Intraveno | 1974 |
Insulin response to glucose and tolbutamide in "essential" versus "pancreatic" mild glucose intolerance.
Topics: Adult; Blood Glucose; Body Weight; Chronic Disease; Diabetes Mellitus; Glucose; Glucose Tolerance Te | 1974 |
Active chronic hepatitis in the elderly.
Topics: Age Factors; Aged; Azathioprine; Chronic Disease; Diabetes Mellitus; Female; Hepatitis; Hepatomegaly | 1974 |
The diagnostic value of oral glucose tolerance test and combined B-cell stimulation in chronic pancreatitis.
Topics: Administration, Oral; Adult; Antigens; Blood Glucose; Chronic Disease; Diabetes Mellitus; Glucagon; | 1973 |
Selective loss of beta cell response to glucose in chronic pancreatitis.
Topics: Administration, Oral; Antigens; Arginine; Cholecystokinin; Chronic Disease; Glucagon; Glucose; Human | 1974 |
[Endocrine secretory disorders in chronic pancreatitis (author's transl)].
Topics: Adult; Blood Glucose; Chronic Disease; Female; Glucagon; Glucose; Humans; Insulin; Islets of Langerh | 1974 |
[Letter: Tolbutamide therapy of fatty liver?].
Topics: Chronic Disease; Fatty Liver; Hepatitis; Humans; Hypoglycemia; Tolbutamide | 1973 |
[Pharmacokinetics of glymidine (glycodiazine) and tolbutamide in acute and chronic liver diseases].
Topics: Acute Disease; Adolescent; Adult; Aged; Biotransformation; Chronic Disease; Ethers; Fructose; Half-L | 1973 |
[Induction of drug-catabolizing enzymes in chronic alcoholics].
Topics: Alcoholism; Antipyrine; Chronic Disease; Enzyme Induction; Humans; Microsomes, Liver; Pharmaceutical | 1974 |
Tolbutamide tolerance test in post-pancreatitis hypoglycemia.
Topics: Adult; Chronic Disease; Female; Humans; Hyperplasia; Hypoglycemia; Injections, Intravenous; Insulin; | 1969 |
[What is reliable in the therapy of diabetes mellitus?].
Topics: Carbutamide; Chlorpropamide; Chronic Disease; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nep | 1970 |
[B-cell stimulation in chronic and chronic relapsing pancreatitis].
Topics: Adult; Blood Glucose; Chronic Disease; Glucagon; Glucose; Humans; Insulin; Islets of Langerhans; Pan | 1971 |
Comparison of blood clearance of ethanol and tolbutamide and the activity of hepatic ethanol-oxidizing and drug-metabolizing enzymes in chronic alcoholic subjects.
Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Aniline Compounds; Chronic Disease; Ethanol; Half-Life; | 1972 |
[Effect of long-term corticotherapy on carbohydrate tolerance in patients with chronic bronchial asthma].
Topics: Adult; Age Factors; Aged; Asthma; Carbohydrate Metabolism; Chronic Disease; Glucocorticoids; Glucose | 1972 |
Tryptophan metabolism in liver disease.
Topics: Adult; Aged; Amino Acids; Ammonia; Brain Diseases; Chronic Disease; Diabetes Complications; Diabetes | 1971 |
Half-life of tolbutamide in patients with chronic respiratory failure.
Topics: Adolescent; Adult; Child; Chronic Disease; Half-Life; Humans; Hypercapnia; Injections, Intravenous; | 1971 |
[Chronic pancreatitis--symptoms, diagnosis, therapy].
Topics: Amylases; Chronic Disease; Chymotrypsin; Cytodiagnosis; Diet Therapy; Duodenum; Feces; Humans; Intes | 1969 |
[Therapy of chronic hepatitis and liver cirrhosis with the oral antidiabetic tolbutamide (Orabet)].
Topics: Adolescent; Adult; Aged; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Middle Aged; Tolbutami | 1969 |
[Variations of glycemia and insulinemia induced by glucose and tolbutamide in chronic alcoholics].
Topics: Alcoholism; Blood Glucose; Chronic Disease; Female; Glucose; Humans; Insulin; Male; Tolbutamide | 1970 |
[Latent diabetic metabolic condition and glaucoma simplex].
Topics: Adult; Aged; Chronic Disease; Female; Glaucoma; Humans; Male; Middle Aged; Prediabetic State; Tolbut | 1970 |
[Insulinemia and chronic pancreatitis].
Topics: Adult; Chronic Disease; Female; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Male; Middle Aged; | 1970 |
Evolution of diabetes mellitus from hypoglycemia.
Topics: Adolescent; Blood Glucose; Child; Chronic Disease; Diabetes Mellitus, Type 1; Drug Tolerance; Female | 1971 |
Effect of intravenous tolbutamide on serum insulin levels in pancreatic diabetes.
Topics: Adult; Aged; Blood Glucose; Chronic Disease; Diabetes Mellitus; Female; Humans; Injections, Intraven | 1969 |
[Effect of antidiabetics on the fat metabolism of alloxan-diabetic rats].
Topics: Animals; Chronic Disease; Depression, Chemical; Diabetes Mellitus, Experimental; Fatty Acids, Nonest | 1969 |
[Behavior of the glycogenase level of the serum under tolbutamide in chronic pancreatitis].
Topics: Amylases; Chronic Disease; Female; Glucosyltransferases; Humans; Male; Pancreatitis; Tolbutamide | 1965 |