tolbutamide has been researched along with Carcinoma in 7 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The data indicate: 1) insulin-secreting islet cell tumors have decreased storage capacity for insulin, 2) elevated concentration of proinsulin in tumors may be due to decreased capacity to store insulin and in some to decreased conversion of proinsulin to insulin as well, 3) tolbutamide stimulates the exaggerated release of a relatively constant fraction of insulin stored in adenomas." | 5.26 | Insulin, proinsulin, glucagon and gastrin in pancreatic tumors and in plasma of patients with organic hyperinsulinism. ( Fajans, SS; Floyd, JC; Hayashi, M; Pek, S, 1977) |
| "The inhibitory effect of epinephrine on basal and tolbutamide-stimulated insulin release was studied in 5 patients with hyperinsulinemic hypoglycemia." | 3.65 | Hyperinsulinemic hypoglycemia: effect of epinephrine suppression. ( Bandisode, MS; Boshell, BR; Buse, J; Buse, MG; Kansal, PC; Roddam, RF, 1977) |
| "The data indicate: 1) insulin-secreting islet cell tumors have decreased storage capacity for insulin, 2) elevated concentration of proinsulin in tumors may be due to decreased capacity to store insulin and in some to decreased conversion of proinsulin to insulin as well, 3) tolbutamide stimulates the exaggerated release of a relatively constant fraction of insulin stored in adenomas." | 1.26 | Insulin, proinsulin, glucagon and gastrin in pancreatic tumors and in plasma of patients with organic hyperinsulinism. ( Fajans, SS; Floyd, JC; Hayashi, M; Pek, S, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BERKOWITZ, D | 1 |
| GREENBERG, L | 1 |
| GLASSMAN, S | 1 |
| LUEHRS, W | 1 |
| CHROMETZKA, K | 1 |
| Hayashi, M | 1 |
| Floyd, JC | 1 |
| Pek, S | 1 |
| Fajans, SS | 1 |
| Kansal, PC | 1 |
| Boshell, BR | 1 |
| Buse, J | 1 |
| Bandisode, MS | 1 |
| Roddam, RF | 1 |
| Buse, MG | 1 |
| Marks, V | 1 |
| Greenwood, FC | 1 |
| Howorth, PJ | 1 |
| Samols, E | 1 |
| Capen, CC | 1 |
| Martin, SL | 1 |
| Freeman, RG | 1 |
| Murtishaw, W | 1 |
| Knox, JM | 1 |
7 other studies available for tolbutamide and Carcinoma
| Article | Year |
|---|---|
The intravenous tolbutamide test as a diagnostic aid in carcinoma of the pancreas.
Topics: Carcinoma; Diabetes Mellitus; Humans; Pancreatic Neoplasms; Tolbutamide | 1962 |
[ON ENZYMATIC ALTERATION OF GLYCOLYSIS IN EHRLICH ASCITES TUMOR CELLS].
Topics: Animals; Biguanides; Carbohydrate Metabolism; Carcinoma; Carcinoma, Ehrlich Tumor; Glucose; Glycolys | 1964 |
Insulin, proinsulin, glucagon and gastrin in pancreatic tumors and in plasma of patients with organic hyperinsulinism.
Topics: Adenoma; Adenoma, Islet Cell; Adolescent; Adult; Aged; Antigen-Antibody Reactions; Carcinoma; Female | 1977 |
Hyperinsulinemic hypoglycemia: effect of epinephrine suppression.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Carcinoma; Epinephrine; Female; Humans; Hyperinsulinism; Hyperp | 1977 |
Plasma growth hormone levels in spontaneous hypoglycemia.
Topics: Adenoma, Islet Cell; Adrenal Gland Diseases; Adult; Aged; Carcinoma; Cholangitis; Deficiency Disease | 1967 |
Hyperinsulinism in dogs with neoplasia of the pancreatic islets. A clinical, pathologic, and ultrastructural study.
Topics: Adenoma; Animals; Blood Glucose; Carcinoma; Dog Diseases; Dogs; Glucose Tolerance Test; Hyperinsulin | 1969 |
Tissue culture techniques in the study of cell photobiology and phototoxicity.
Topics: Animals; Antimalarials; Carcinoma; Cell Line; Coloring Agents; Coumarins; Culture Media; Culture Tec | 1970 |