tolbutamide has been researched along with Carcinoma, Hepatocellular in 8 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tolbutamide effect was rapidly exerted and insulin-independent." | 1.29 | The inhibitory effect of tolbutamide on phosphoenolpyruvate carboxykinase activity in rat hepatoma H4IIE cells. ( Emoto, M; Inoue, Y; Kaku, K; Kaneko, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuda, H | 1 |
| Ebara, M | 1 |
| Okuyama, M | 1 |
| Sugiura, N | 1 |
| Yoshikawa, M | 1 |
| Saisho, H | 1 |
| Shimizu, R | 1 |
| Motoji, N | 1 |
| Shigematsu, A | 1 |
| Watayo, T | 1 |
| GINSBERG, DM | 1 |
| Emoto, M | 1 |
| Inoue, Y | 1 |
| Kaku, K | 1 |
| Kaneko, T | 1 |
| Colwell, JA | 1 |
| Wilber, JF | 1 |
| Greengard, O | 1 |
| Dewey, HK | 1 |
| Vinik, AI | 2 |
| Pooler, W | 1 |
| Deppe, WM | 1 |
| Kumar, D | 1 |
| Mehtalia, SD | 1 |
| Miller, LV | 1 |
1 review available for tolbutamide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
HYPOGLYCEMIA ASSOCIATED WITH EXTRAPANCREATIC NEOPLASMS, WITH A NOTE ON OTHER UNUSUAL FORMS OF HYPOGLYCEMIA.
Topics: Adrenogenital Syndrome; Carcinoma, Hepatocellular; Drug Therapy; Glycogen Storage Disease Type I; Hu | 1964 |
7 other studies available for tolbutamide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Increased metabolizing activities of the tricarboxylic acid cycle and decreased drug metabolism in hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Chromatography, Thin Layer; Citric Acid Cycle; Diazepam; Fibrosis; Humans | 2002 |
The inhibitory effect of tolbutamide on phosphoenolpyruvate carboxykinase activity in rat hepatoma H4IIE cells.
Topics: Animals; Carcinoma, Hepatocellular; Cyclic AMP; Gluconeogenesis; Liver; Phosphoenolpyruvate Carboxyk | 1993 |
Studies of insulin and growth hormone secretion in a subject with hepatoma and gypoglycemia.
Topics: Adipose Tissue; Adult; Animals; Arginine; Blood Glucose; Carcinoma, Hepatocellular; Dexamethasone; F | 1971 |
The effect of glucose ingestion on basal and induced enzyme levels in rat tissues.
Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animals; Brain; Carcinoma, Hepatocellular; Dietary Carbo | 1973 |
Carbohydrate metabolism in patients with primary hepatocellular carcinoma.
Topics: Adult; Aged; Antigens; Blood Glucose; Carcinoma, Hepatocellular; Fatty Acids, Nonesterified; Female; | 1973 |
Studies on hypoglycaemia in primary carcinoma of the liver. A case report and review of pathogenetic mechanisms.
Topics: Adult; Carcinoma, Hepatocellular; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Growth | 1974 |
Diagnostic use of glucagon-induced insulin response. Studies in patients with insulinoma or other hypoglycemic conditions.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Carcinoma, Hepatocellular; Child; Diagnosis, Differ | 1974 |