tolbutamide has been researched along with Cancer of Pancreas in 159 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study investigated the interactions of calcium and somatostatin analogues on peptide release in two patients, one with a glucagonoma (patient A) and one with an insulinoma (patient B)." | 9.08 | Calcium reverses octreotide inhibition of insulin and glucagon levels in patients with insulinoma and glucagonoma. ( O'Dorisio, TM; Thompson, CS; Woltering, EA, 1996) |
| "The plasma glucose and insulin responses to intravenous administration of tolbutamide in patients with insulinoma and healthy control subjects were compared to determine the sensitivity and specificity of the intravenous tolbutamide test for the diagnosis of insulinoma." | 7.67 | Diagnostic interpretation of the intravenous tolbutamide test for insulinoma. ( McMahon, MM; O'Brien, PC; Service, FJ, 1989) |
| "Thus, alpha-TC glucagonoma cells contain ATP-sensitive K+ channels that regulate glucagon release, yet allow inhibition of hormone release by glucose." | 5.29 | Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. ( Buettger, C; Epstein, AJ; Hang, TL; Matschinsky, FM; Ronner, P, 1993) |
| "Five cases of somatostatinoma are reported, four being primarily located in the pancreas and one in the duodenum." | 5.27 | Five cases of somatostatinoma: clinical heterogeneity and diagnostic usefulness of basal and tolbutamide-induced hypersomatostatinemia. ( Couturier, E; Gepts, W; Pipeleers, D; Reynders, J; Somers, G, 1983) |
| " This study investigated the interactions of calcium and somatostatin analogues on peptide release in two patients, one with a glucagonoma (patient A) and one with an insulinoma (patient B)." | 5.08 | Calcium reverses octreotide inhibition of insulin and glucagon levels in patients with insulinoma and glucagonoma. ( O'Dorisio, TM; Thompson, CS; Woltering, EA, 1996) |
| "The response of insulinoma tissue to glucose, alpha-ketoisocaproate, and the modifiers of insulin release, tolbutamide, isoproterenol, and acetylcholine, was studied." | 3.67 | Pharmacological modifications of insulin release in vitro from fuel-responsive transplantable insulinomas. ( Ferguson, DC; Hoenig, M; Matschinsky, FM, 1984) |
| "The plasma glucose and insulin responses to intravenous administration of tolbutamide in patients with insulinoma and healthy control subjects were compared to determine the sensitivity and specificity of the intravenous tolbutamide test for the diagnosis of insulinoma." | 3.67 | Diagnostic interpretation of the intravenous tolbutamide test for insulinoma. ( McMahon, MM; O'Brien, PC; Service, FJ, 1989) |
| "In order to clarify the mechanism of insulin secretion, responses of insulin (IRI) and C-peptide (CPR) in plasma to various stimuli were investigated in normal subjects and patients with diabetes mellitus, liver cirrhosis, chronic nephritis or insulinoma." | 3.66 | Analysis of insulin secretion based on changes in plasma insulin and C-peptide in man. ( Kobayashi, T; Nihei, J; Ohneda, A; Sakai, T, 1982) |
| "The inhibitory effect of epinephrine on basal and tolbutamide-stimulated insulin release was studied in 5 patients with hyperinsulinemic hypoglycemia." | 3.65 | Hyperinsulinemic hypoglycemia: effect of epinephrine suppression. ( Bandisode, MS; Boshell, BR; Buse, J; Buse, MG; Kansal, PC; Roddam, RF, 1977) |
| "Insulinomas are β-cell tumors that cause hypoglycemia through inappropriate secretion of insulin." | 1.42 | Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro. ( Guiot, Y; Henquin, JC; Nenquin, M; Rahier, J; Sempoux, C, 2015) |
| " Moreover, the effectiveness of tolbutamide on [Ca(2+)](i) increase was reduced and the dose-response relations for insulin secretion induced by the agent was shifted toward the right in the UCP1-expressing cells." | 1.31 | Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells. ( Aso, K; Fukudome, M; Hashiguchi, H; Ishihara, H; Kakei, M; Koriyama, N; Nakazaki, M; Oka, Y; Tei, C; Yada, T, 2002) |
| " By applying the patch-clamp technique, dose-response curves for ATP and the sulfonylurea tolbutamide were obtained in inside-out patches." | 1.30 | RIN14B: a pancreatic delta-cell line that maintains functional ATP-dependent K+ channels and capability to secrete insulin under conditions where it no longer secretes somatostatin. ( Berggren, PO; Bränström, R; Höög, A; Larsson, O; Wahl, MA, 1997) |
| "Thus, alpha-TC glucagonoma cells contain ATP-sensitive K+ channels that regulate glucagon release, yet allow inhibition of hormone release by glucose." | 1.29 | Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. ( Buettger, C; Epstein, AJ; Hang, TL; Matschinsky, FM; Ronner, P, 1993) |
| "Therefore, the hyperproinsulinemia of type 2 diabetes and in insulinoma patients may be caused by additional defects in the proinsulin to insulin conversion process." | 1.28 | Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin. ( Creutzfeldt, W; Nauck, MA; Siegel, EG, 1991) |
| "Five cases of somatostatinoma are reported, four being primarily located in the pancreas and one in the duodenum." | 1.27 | Five cases of somatostatinoma: clinical heterogeneity and diagnostic usefulness of basal and tolbutamide-induced hypersomatostatinemia. ( Couturier, E; Gepts, W; Pipeleers, D; Reynders, J; Somers, G, 1983) |
| "If a diagnosis of insulinoma is in doubt after several overnight fasts, C-peptide suppression test should be carried out since the test is safe and convenient." | 1.27 | [Studies on the diagnosis of insulinoma]. ( Kurihara, Y, 1987) |
| "All of the clinical manifestations of glucagonoma syndrome so far reported in the literature were noted but there was no evidence indicating the presence of multiple endocrine adenomatosis." | 1.26 | A case with glucagonoma syndrome--endocrine and metabolic studies. ( Fukushima, H; Kitoh, M; Konno, T; Takemiya, M; Uzawa, H; Yamaguchi, K, 1981) |
| "Transient neurologic deficits and EEG abnormalities can be observed during hypoglycemia." | 1.26 | Insulinoma: clinical and diagnostic features of 60 consecutive cases. ( Dale, AJ; Elveback, LR; Jiang, NS; Service, FJ, 1976) |
| "Insular hyperplasia was the only abnormal factor determined to be present." | 1.25 | Hypoglycemia and insular hyperplasia: review of 148 cases. ( Basoli, A; Carboni, M; Patrassi, N; Stefanini, P, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 138 (86.79) | 18.7374 |
| 1990's | 13 (8.18) | 18.2507 |
| 2000's | 6 (3.77) | 29.6817 |
| 2010's | 2 (1.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henquin, JC | 1 |
| Nenquin, M | 1 |
| Guiot, Y | 1 |
| Rahier, J | 2 |
| Sempoux, C | 1 |
| Hiram-Bab, S | 1 |
| Shapira, Y | 1 |
| Gershengorn, MC | 1 |
| Oron, Y | 1 |
| Cosgrove, KE | 2 |
| Antoine, MH | 1 |
| Lee, AT | 1 |
| Barnes, PD | 1 |
| de Tullio, P | 1 |
| Clayton, P | 1 |
| McCloy, R | 1 |
| De Lonlay, P | 1 |
| Nihoul-Fékété, C | 1 |
| Robert, JJ | 1 |
| Saudubray, JM | 1 |
| Lindley, KJ | 1 |
| Hussain, K | 1 |
| Aynsley-Green, A | 1 |
| Pirotte, B | 1 |
| Lebrun, P | 1 |
| Dunne, MJ | 3 |
| FAJANS, SS | 2 |
| SCHNEIDER, JM | 1 |
| SCHTEINGART, DE | 1 |
| CONN, JW | 2 |
| JOHNSTON, R | 1 |
| GOETZ, FC | 1 |
| ZIMMERMANN, B | 1 |
| BERKOWITZ, D | 2 |
| GREENBERG, L | 1 |
| GLASSMAN, S | 1 |
| LEGER, L | 1 |
| MAGDELAINE, M | 1 |
| CREUTZFELDT, W | 4 |
| WILLE, K | 1 |
| KAUP, H | 1 |
| BUSE, J | 2 |
| MARSHALL, JN | 1 |
| BRADHAM, R | 1 |
| OBERMAN, H | 1 |
| BUSE, MG | 2 |
| UNDERWOOD, LE | 1 |
| JACOBS, NM | 1 |
| STAFFIERI, JJ | 1 |
| LENCIONI, LJ | 1 |
| EBERHARDT, DR | 1 |
| GORNI, DL | 1 |
| CUNNINGHAM, GC | 1 |
| BOUMAN, PR | 1 |
| REESE, JL | 1 |
| KISER, WJ | 1 |
| MATASSARIN, BM | 1 |
| MAHLER, RJ | 1 |
| GRANN, V | 1 |
| PURDY, R | 1 |
| SCHOLTZ, DA | 1 |
| KAHIL, ME | 1 |
| BROWN, H | 1 |
| DOBSON, HL | 1 |
| ROBERTS, HJ | 1 |
| SHIMIZU, J | 2 |
| KOBAYASHI, J | 2 |
| OTA, T | 2 |
| YOSHIDA, H | 2 |
| FUJII, H | 2 |
| SAKAKIBARA, N | 2 |
| ARIMASA, S | 2 |
| BLACK, KO | 1 |
| BIRNSTINGL, MA | 1 |
| FLOYD, JC | 1 |
| KNOPF, RF | 1 |
| HECKER, E | 1 |
| FROMM, GA | 1 |
| NAJENSON, H | 1 |
| FARAONI, H | 1 |
| FORD, HC | 1 |
| BAILEY, RE | 1 |
| MARRACK, D | 1 |
| ROSE, FC | 1 |
| MARKS, V | 3 |
| Merglen, A | 1 |
| Theander, S | 1 |
| Rubi, B | 1 |
| Chaffard, G | 1 |
| Wollheim, CB | 1 |
| Maechler, P | 1 |
| Crofford, OB | 1 |
| Uebersax, R | 1 |
| Cananau, S | 1 |
| Beuret, P | 1 |
| Zahnd, G | 1 |
| Jara Albarrán, A | 1 |
| Caballero Asensi, A | 1 |
| García Peris, P | 1 |
| Coste, A | 1 |
| Toledano, E | 1 |
| Gorospe, C | 1 |
| Caviola, E | 1 |
| Palacios Mateos, JM | 1 |
| Pipeleers, D | 2 |
| Couturier, E | 1 |
| Gepts, W | 2 |
| Reynders, J | 1 |
| Somers, G | 2 |
| Hendriks, T | 1 |
| Jansen, JB | 1 |
| van Tongeren, JH | 1 |
| Hoenig, M | 1 |
| Ferguson, DC | 1 |
| Matschinsky, FM | 2 |
| Service, FJ | 3 |
| Nelson, RL | 1 |
| Buysschaert, M | 1 |
| Lambotte, L | 1 |
| Reynaert, M | 1 |
| Kestens, PJ | 1 |
| Ketelslegers, JM | 1 |
| Lambert, AE | 1 |
| Deliège, M | 1 |
| Jardon-Jeghers, C | 1 |
| Fukushima, H | 1 |
| Yamaguchi, K | 1 |
| Uzawa, H | 1 |
| Kitoh, M | 1 |
| Takemiya, M | 1 |
| Konno, T | 1 |
| Ohneda, A | 2 |
| Kobayashi, T | 2 |
| Nihei, J | 2 |
| Kazeĭ, NS | 1 |
| Khar'kovaia, VV | 1 |
| Petrukhin, VI | 1 |
| Tsaguriia, EG | 1 |
| Sakai, T | 1 |
| Gastineau, CF | 1 |
| Matsumoto, K | 1 |
| Fukunaga, K | 1 |
| Miyazaki, J | 2 |
| Shichiri, M | 1 |
| Miyamoto, E | 1 |
| Khan, RN | 1 |
| Hales, CN | 1 |
| Ozanne, SE | 1 |
| Adogu, AA | 1 |
| Ashford, ML | 1 |
| Sekine, N | 1 |
| Yamashita, N | 1 |
| Kojima, I | 1 |
| Ogata, E | 1 |
| Ronner, P | 1 |
| Hang, TL | 1 |
| Epstein, AJ | 1 |
| Buettger, C | 1 |
| Sjöholm, A | 1 |
| Arkhammar, P | 1 |
| Welsh, N | 1 |
| Bokvist, K | 1 |
| Rorsman, P | 1 |
| Hallberg, A | 1 |
| Nilsson, T | 1 |
| Welsh, M | 1 |
| Berggren, PO | 2 |
| Thompson, CS | 1 |
| O'Dorisio, TM | 1 |
| Woltering, EA | 1 |
| Martín, F | 1 |
| Soria, B | 1 |
| Khoo, S | 1 |
| Cobb, MH | 1 |
| Bränström, R | 1 |
| Höög, A | 1 |
| Wahl, MA | 1 |
| Larsson, O | 1 |
| Tian, YA | 1 |
| Johnson, G | 1 |
| Ashcroft, SJ | 1 |
| Chapman, JC | 1 |
| McClenaghan, NH | 1 |
| Hashmi, MN | 1 |
| Shepherd, RM | 1 |
| Giesberts, AN | 1 |
| White, SJ | 1 |
| Ammälä, C | 1 |
| Flatt, PR | 1 |
| Kulkarni, RN | 1 |
| Wang, ZL | 1 |
| Wang, RM | 1 |
| Smith, DM | 1 |
| Ghatei, MA | 1 |
| Bloom, SR | 1 |
| Su, J | 1 |
| Yu, H | 1 |
| Lenka, N | 1 |
| Hescheler, J | 1 |
| Ullrich, S | 1 |
| Park, KH | 1 |
| Kim, SW | 1 |
| Bae, YH | 1 |
| Nakazaki, M | 1 |
| Kakei, M | 1 |
| Ishihara, H | 1 |
| Koriyama, N | 1 |
| Hashiguchi, H | 1 |
| Aso, K | 1 |
| Fukudome, M | 1 |
| Oka, Y | 1 |
| Yada, T | 1 |
| Tei, C | 1 |
| Sailer, R | 1 |
| Katoh, E | 1 |
| Drüneklee, D | 1 |
| Kovaciecek, S | 1 |
| Berger, M | 1 |
| Tragl, KH | 1 |
| Mayr, WR | 1 |
| Del Arbol, JL | 1 |
| Jimenez Alonso, J | 1 |
| Yañez, AP | 1 |
| Van Kersen, F | 2 |
| Escobar-Jimenez, F | 1 |
| DeLa Higuare, J | 1 |
| Zubeldia, R | 1 |
| Diaz-Flores, L | 1 |
| Arcelus, I | 1 |
| De Nutte, N | 1 |
| De Vroede, M | 1 |
| Berger, H | 1 |
| Adibi, SA | 1 |
| Morse, EL | 1 |
| Amin, PM | 1 |
| Doi, K | 1 |
| Oneda, A | 2 |
| Maruhama, Y | 1 |
| Itabashi, H | 1 |
| Horigome, K | 1 |
| Yanbe, A | 1 |
| Scuro, LA | 1 |
| Lo Cascio, V | 1 |
| Adami, S | 1 |
| Galvanini, G | 1 |
| Bianchi, I | 1 |
| Cominacini, L | 1 |
| Corgnati, A | 1 |
| Dale, AJ | 1 |
| Elveback, LR | 1 |
| Jiang, NS | 1 |
| Biliotti, G | 2 |
| Stefani, P | 2 |
| Macchini, M | 2 |
| Eriksson, M | 1 |
| Erwald, R | 2 |
| Hed, R | 2 |
| Nygren, A | 2 |
| Patricny, J | 1 |
| Röjdmark, S | 2 |
| Sundblad, L | 2 |
| Wiechel, KL | 2 |
| Kansal, PC | 1 |
| Boshell, BR | 1 |
| Bandisode, MS | 1 |
| Roddam, RF | 1 |
| Schauder, P | 1 |
| Frerichs, H | 2 |
| Andreani, D | 1 |
| Tamburrano, S | 1 |
| Tamburrano, G | 1 |
| Natoli, C | 1 |
| Goto, Y | 1 |
| Umezu, M | 1 |
| Muszyński, J | 1 |
| Raptis, S | 1 |
| Zoupas, C | 1 |
| Dimitriadis, G | 1 |
| Moulopoulos, S | 1 |
| Nauck, MA | 1 |
| Siegel, EG | 1 |
| Yule, DI | 1 |
| Gallacher, DV | 1 |
| Petersen, OH | 1 |
| Thivolet, CH | 1 |
| Demidem, A | 1 |
| Haftek, M | 1 |
| Durand, A | 1 |
| Bertrand, J | 1 |
| McMahon, MM | 1 |
| O'Brien, PC | 1 |
| Grimaldi, KA | 1 |
| Siddle, K | 1 |
| Hutton, JC | 1 |
| Budmiger, H | 1 |
| Bühler, H | 1 |
| Häcki, W | 1 |
| Stamm, B | 1 |
| Streuli, R | 1 |
| Ammann, R | 1 |
| Kurihara, Y | 1 |
| Sinagra, D | 1 |
| Randazzo, C | 1 |
| Cohen, MS | 1 |
| Bower, RH | 1 |
| Fidler, SM | 1 |
| Johnsonbaugh, RE | 1 |
| Sode, J | 1 |
| Miles, LE | 1 |
| Smith, M | 1 |
| Tompkins, RK | 1 |
| Hardacre, JM | 1 |
| Tzagournis, M | 1 |
| Greider, M | 1 |
| Colwell, JA | 1 |
| Furey, WL | 1 |
| Frawley, TF | 1 |
| Pensuwan, S | 1 |
| Knoke, M | 1 |
| Reding, R | 1 |
| Markert, J | 1 |
| Glöckner, E | 1 |
| Schmidt, H | 1 |
| Abe, Y | 1 |
| Shigeta, Y | 1 |
| Nakamura, K | 1 |
| Kohama, M | 1 |
| Walsh, JH | 1 |
| Sleisenger, MH | 1 |
| Irmer, W | 1 |
| Daweke, H | 1 |
| Wedell, J | 1 |
| Grüneklee, D | 1 |
| Schmitt, H | 1 |
| Jünemann, A | 1 |
| Bottermann, P | 1 |
| Schwarz, K | 1 |
| Kollmannsberger, A | 1 |
| Kopetz, K | 1 |
| Hartsuck, JM | 1 |
| Brooks, JR | 1 |
| Abe, M | 1 |
| Ikeda, Y | 1 |
| Yaginuma, M | 1 |
| Shimizu, N | 1 |
| Williams, C | 1 |
| McKiddie, MT | 1 |
| Buchanan, KD | 1 |
| Abernethy, RJ | 1 |
| Ewer, RW | 1 |
| Deiss, WP | 1 |
| Gorden, P | 3 |
| Roth, J | 2 |
| DePeyster, FA | 1 |
| Grunt, JA | 1 |
| Pallotta, JA | 1 |
| Soeldner, JS | 1 |
| Felig, P | 1 |
| Sachs, FL | 1 |
| Landsberg, L | 1 |
| Brooten, P | 1 |
| Sodoyez, JC | 1 |
| Sodoyez-Goffaux, F | 1 |
| Lefebvre, PJ | 1 |
| Foà, PP | 1 |
| van de Weyer, KH | 1 |
| Overzier, C | 1 |
| Kümmerle, F | 1 |
| Catellier, C | 1 |
| Ringuet, J | 1 |
| Rivière, L | 1 |
| Plamondon, C | 1 |
| Melani, F | 1 |
| Ryan, WG | 1 |
| Rubenstein, AH | 1 |
| Steiner, DF | 1 |
| Remigio, PA | 1 |
| Grinvalsky, HT | 1 |
| Rubay, J | 1 |
| Parmentier, J | 1 |
| Gutman, RA | 1 |
| Lazarus, NR | 1 |
| Penhos, JC | 1 |
| Fajans, S | 1 |
| Recant, L | 1 |
| Doolas, A | 1 |
| AvRuskin, TW | 1 |
| Coran, AG | 1 |
| Crigler, JF | 1 |
| Schwartz, JF | 1 |
| Zwiren, GT | 1 |
| Berkowitz, S | 1 |
| Parrish, JE | 1 |
| Field, JB | 1 |
| Nardi, GL | 1 |
| Wolfe, WG | 1 |
| Mullen, DC | 1 |
| Silver, D | 1 |
| Khurana, RC | 1 |
| Klayton, R | 1 |
| Jung, Y | 1 |
| Gonzalez, AR | 1 |
| Dhawer, VP | 1 |
| Corredor, DG | 1 |
| Sieracki, JC | 1 |
| Danowski, TS | 1 |
| Balsam, MJ | 1 |
| Baker, L | 1 |
| Bishop, HC | 1 |
| Hummeler, K | 1 |
| Yakovac, WC | 1 |
| Kaye, R | 1 |
| Marions, O | 1 |
| Nandorf, R | 1 |
| Rochiccioli, P | 1 |
| Delsol, G | 1 |
| Juskiewinski, S | 1 |
| Ghisolfi, J | 1 |
| Ribot, C | 1 |
| Gabarou, JP | 1 |
| Fabre, J | 1 |
| Dalous, A | 1 |
| Kavlie, H | 1 |
| White, TT | 1 |
| Rubányi, P | 1 |
| Siklós, I | 1 |
| Cameron, GS | 1 |
| Wright, AD | 1 |
| Tuttle, RJ | 1 |
| Cole, FM | 1 |
| Birchard, E | 1 |
| Felber, JP | 1 |
| Schmidt, WM | 1 |
| Levey, GS | 1 |
| Mintz, DH | 1 |
| Verdy, M | 1 |
| Leboeuf, G | 1 |
| Bourbeau, D | 1 |
| Duclos, P | 1 |
| Schein, P | 1 |
| Kahn, R | 1 |
| Wells, S | 1 |
| Devita, VT | 1 |
| Basoli, A | 2 |
| Patrassi, N | 2 |
| Perrotta, G | 1 |
| De Bernardinis, G | 1 |
| Carboni, M | 2 |
| Standl, E | 1 |
| Kolb, HJ | 1 |
| Shatney, CH | 1 |
| Grage, TB | 1 |
| Fujii, K | 1 |
| Yamagata, S | 1 |
| Sassaki, R | 1 |
| Shoji, T | 1 |
| Luyckx, A | 1 |
| Lefebvre, P | 1 |
| Kuroda, A | 1 |
| Wada, Y | 1 |
| Ishihara, Y | 1 |
| Sato, N | 1 |
| Tajima, Y | 1 |
| Kumar, D | 1 |
| Mehtalia, SD | 1 |
| Miller, LV | 1 |
| Stefanini, P | 1 |
| Hendricks, CM | 1 |
| Kahn, CR | 1 |
| Lucke, C | 1 |
| Grögler, F | 1 |
| Mitzkat, HJ | 1 |
| Vance, JE | 1 |
| Stoll, RW | 1 |
| Kitabchi, AE | 1 |
| Williams, RH | 1 |
| Wood, FC | 1 |
| Soler, NG | 1 |
| Exon, PD | 1 |
| Paton, A | 1 |
| Laurent, J | 1 |
| Heully, F | 1 |
| Debry, G | 1 |
| Lubetzki, J | 1 |
| Duprey, J | 1 |
| Capen, CC | 1 |
| Martin, SL | 1 |
| Crepaldi, G | 1 |
| Tiengo, A | 2 |
| Muggeo, M | 2 |
| Trisotto, A | 2 |
| Federspil, G | 2 |
| Scandellari, C | 1 |
| Wüstenberg, PW | 1 |
| Wolff, G | 1 |
| Deckert, T | 1 |
| Kolendorf, K | 1 |
| Persson, I | 1 |
| Worning, H | 1 |
| Thimm, R | 1 |
| Frezzato, S | 1 |
| Macrì, C | 1 |
| Vianello, A | 1 |
| Schneider, H | 1 |
| Colombo, JP | 1 |
| Jorke, D | 1 |
| Hubrig, M | 1 |
| Marabelli, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| TArgeting Type 1 Diabetes Using POLyamines (TADPOL): A Randomized, Double-Masked, Placebo-Controlled Phase 2 Study to Evaluate the Efficacy and Safety of Difluoromethylornithine (DFMO) to Preserve Insulin Production in Type 1 Diabetes[NCT05594563] | Phase 2 | 70 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for tolbutamide and Cancer of Pancreas
| Article | Year |
|---|---|
[POSSIBILITIES AND LIMITATIONS IN THE DETERMINATION OF INSULIN IN BLOOD IN THE DIAGNOSIS OF HYPERINSULINISM].
Topics: Adenoma, Islet Cell; Blood; Diagnosis; Humans; Hyperglycemia; Hyperinsulinism; Insulin; Leucine; Pan | 1963 |
[Clinical significance of insulin determination].
Topics: Adenoma, Islet Cell; Diabetes Mellitus; Gastrointestinal Hormones; Glucose; Humans; Hypoglycemia; In | 1978 |
[Diagnostic and therapeutic use of the artificial endocrine pancreas in hypoglycemia].
Topics: Humans; Hypoglycemia; Insulin Infusion Systems; Insulinoma; Monitoring, Physiologic; Pancreatic Neop | 1988 |
Hypoglycemia: tolbutamide and leucine tests in insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Female; Glucagon; Glucose Tolerance Test; Humans; Hyper | 1968 |
[The role of pancreatic diagnosis for the correct indication for pancreatic surgery].
Topics: Adenoma, Islet Cell; Amylases; Clinical Enzyme Tests; Diagnosis, Differential; Exudates and Transuda | 1967 |
Functioning tumors of the pancreas.
Topics: Adenoma, Islet Cell; Diarrhea; Digestive System; Fasting; Gastrins; Glucagon; Glucose; Glucose Toler | 1968 |
[Pancreatic function tests].
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Huma | 1969 |
Steps in the diagnosis of three functioning endocrine tumors.
Topics: Adenoma, Islet Cell; Blood Glucose; Diagnosis, Differential; Gastrins; Glucose Tolerance Test; Human | 1971 |
Progress report. Diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Child, Preschool; Diagnosis, Differential; E | 1971 |
Insulinomas.
Topics: Adenoma, Islet Cell; Blood Glucose; Brain Damage, Chronic; Child; Fasting; Female; Humans; Hyperinsu | 1971 |
[Insulinoma].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Child; Diagnosis, Differential; Diagnosti | 1973 |
Plasma proinsulin-like components.
Topics: Adenoma, Islet Cell; Animals; Antigen-Antibody Reactions; Antigens; Blood Glucose; Chromatography, G | 1974 |
[The hypoglycemia syndrome].
Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide | 1970 |
[Hypoglycemia. II].
Topics: Adolescent; Adult; Age Factors; Animals; Blood Glucose; Cricetinae; Diagnosis, Differential; Female; | 1970 |
2 trials available for tolbutamide and Cancer of Pancreas
| Article | Year |
|---|---|
Calcium reverses octreotide inhibition of insulin and glucagon levels in patients with insulinoma and glucagonoma.
Topics: Antineoplastic Agents, Hormonal; Calcium; Glucagon; Glucagonoma; Humans; Hypoglycemic Agents; Infusi | 1996 |
Role of insulin and glucose in the induction of hypoaminoacidemia in man: studies in normal, juvenile diabetic, and insuloma patients.
Topics: Adenoma, Islet Cell; Administration, Oral; Adolescent; Adult; Amino Acids; Blood Glucose; Clinical T | 1975 |
143 other studies available for tolbutamide and Cancer of Pancreas
| Article | Year |
|---|---|
Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro.
Topics: Adult; Aged, 80 and over; Calcium Chloride; Diazoxide; Female; Gene Expression Regulation; Glucose; | 2015 |
Serum deprivation induces glucose response and intercellular coupling in human pancreatic adenocarcinoma PANC-1 cells.
Topics: Adenocarcinoma; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Communication; Cell Cultu | 2012 |
BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.
Topics: Adenosine Triphosphate; Adolescent; Adrenergic alpha-Antagonists; Animals; Benzofurans; Benzothiadia | 2002 |
The diagnostic value of sodium tolbutamide in hypoglycemic states.
Topics: Adenoma, Islet Cell; Blood Glucose; Humans; Hypoglycemic Agents; Insulin; Insulins; Pancreatic Neopl | 1961 |
Insulin-secreting tumor of the pancreas. Report of a case with an untoward response to tolbutamide and with a study of the possible mechanism of postoperative hyperglycemia.
Topics: Adenoma, Islet Cell; Humans; Hyperglycemia; Insulin; Medical Records; Pancreas; Pancreatic Neoplasms | 1960 |
The intravenous tolbutamide test as a diagnostic aid in carcinoma of the pancreas.
Topics: Carcinoma; Diabetes Mellitus; Humans; Pancreatic Neoplasms; Tolbutamide | 1962 |
[Examination of blood sugar balance with the intravenous tolbutamide test].
Topics: Adenoma, Islet Cell; Blood Glucose; Humans; Hypoglycemia; Mesothelioma; Pancreatic Neoplasms; Thorac | 1962 |
[Intravenous injections of glucose, insulin and tolbutamide in healthy persons, diabetics, cirrhotics, and patients with insuloma (together with a contribution on the diagnostic value of the tolbutamide tests)].
Topics: Adenoma, Islet Cell; Blood Glucose; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Inje | 1962 |
FUNCTIONING PANCREATIC ISLET CELL ADENOMA. WITH LEUCINE-INDUCED HYPOGLYCEMIA.
Topics: Adenoma, Islet Cell; Fasting; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neoplasms; Patholog | 1963 |
FAMILIAL ENDOCRINE ADENOMATOSIS. A FAMILY WITH HYPERINSULINISM AS THE PREDOMINANT MANIFESTATION.
Topics: Adenoma; Adenoma, Islet Cell; Adolescent; Carcinoma, Bronchogenic; Child; Clinical Laboratory Techni | 1963 |
[HYPOGLYCEMIC SYNDROME DUE TO HYPERFUNCTIONING ISLET CELL ADENOMA].
Topics: Adenoma, Islet Cell; Clinical Laboratory Techniques; Glucose Tolerance Test; Humans; Hyperinsulinism | 1963 |
TOLBUTAMIDE TOLERANCE IN HYPOGLYCEMIC CHILDREN.
Topics: Adenoma, Islet Cell; Blood Glucose; Child; Hypoglycemic Agents; Neoplasms; Pancreatic Neoplasms; Pha | 1964 |
ISLET CELL ADENOMA. INSULINOMAS AND THE INTRAVENOUS SODIUM TOLBUTAMIDE TEST: A CASE REPORT.
Topics: Adenoma, Islet Cell; Blood Chemical Analysis; Glucose Tolerance Test; Humans; Insulinoma; Pancreatic | 1964 |
FUNCTIONING ISLET CELL ADENOMA.
Topics: Adenoma, Islet Cell; Cerebrovascular Disorders; Diagnosis, Differential; Geriatrics; Humans; Hyperin | 1964 |
SPONTANEOUS HYPOGLYCEMIA: DIAGNOSTIC CONSIDERATIONS AND MANAGEMENT.
Topics: Adenoma, Islet Cell; Diabetes Mellitus; Diagnosis, Differential; Humans; Hypoglycemia; Leucine; Mali | 1964 |
POSTALCOHOLIC HYPOGLYCEMIA VERSUS ISLET CELL TUMOR.
Topics: Adenoma, Islet Cell; Alcoholism; Diagnosis, Differential; Glucose Tolerance Test; Humans; Hypoglycem | 1964 |
PITFALLS IN THE DIFFERENTIAL DIAGNOSIS OF JAUNDICE.
Topics: Alkaline Phosphatase; Anemia; Anemia, Hemolytic; Bile Duct Neoplasms; Blood Chemical Analysis; Diagn | 1964 |
AFTERNOON GLUCOSE TOLERANCE TESTING: A KEY TO THE PATHOGENESIS, EARLY DIAGNOSIS AND PROGNOSIS OF DIABETOGENIC HYPERINSULINISM.
Topics: Adolescent; Alcoholism; Black People; Cortisone; Diabetes Mellitus; Diet; Diet Therapy; Early Diagno | 1964 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancr | 1964 |
[ON ISLET CELL TUMOR].
Topics: Adenoma, Islet Cell; Atropine; Blood Chemical Analysis; Blood Glucose; Epinephrine; Neoplasms; Pancr | 1964 |
INSULINOMA WITH SYMPTOMS FOR THIRTY YEARS.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Geriatrics; Glucose Tolerance Test; Humans; Hypoglycemi | 1964 |
PLASMA INSULIN IN ORGANIC HYPERINSULINISM: COMPARATIVE EFFECTS OF TOLBUTAMIDE, LEUCINE AND GLUCOSE.
Topics: Adenoma, Islet Cell; Blood; Blood Chemical Analysis; Blood Glucose; Glucagon; Glucose; Humans; Hyper | 1964 |
[DIAGNOSTIC VALUE OF TOLBUTAMIDE AND 1-LYSINE IN INSULAR ADENOMA OF THE PANCREAS].
Topics: Adenoma, Islet Cell; Humans; Hyperinsulinism; Hypoglycemia; Lysine; Neoplasms; Pancreatic Neoplasms; | 1964 |
TOLBUTAMIDE TEST: A MISLEADING RESPONSE.
Topics: Adenoma, Islet Cell; Diagnosis, Differential; Glucose; Glucose Tolerance Test; Humans; Hyperinsulini | 1965 |
Glucagon and tolbutamide tests in the recognition of insulinomas.
Topics: Adenoma, Islet Cell; Blood Glucose; Glucagon; Humans; Insulinoma; Pancreatic Neoplasms; Tolbutamide | 1961 |
Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Differentiation; Cell Division; Cytosol; Diazoxide; E | 2004 |
The use of insulin assays in clinical medicine.
Topics: Diabetes Mellitus; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Iodine Isotopes; Pancreati | 1967 |
[Insulinoma: what symptomatology?].
Topics: Adenoma, Islet Cell; Humans; Hypoglycemia; Insulin Coma; Insulinoma; Male; Middle Aged; Pancreatic N | 1984 |
[Tolbutamide plus somatostatin test in the diagnosis of insulinomas].
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Female; Humans; Hypoglycemia; Insulin; Insulinoma; Middle | 1982 |
Five cases of somatostatinoma: clinical heterogeneity and diagnostic usefulness of basal and tolbutamide-induced hypersomatostatinemia.
Topics: Adenoma, Islet Cell; Aged; Blood Glucose; Female; Glucagon; Humans; Insulin; Male; Microscopy, Elect | 1983 |
The glucagonoma syndrome: stimulus-induced plasma responses of circulating glucagon components IRG9000 and IRG3500.
Topics: Adenoma, Islet Cell; Arginine; Calcitonin; Calcium; Chromatography, Gel; Fasting; Female; Glucagon; | 1984 |
Pharmacological modifications of insulin release in vitro from fuel-responsive transplantable insulinomas.
Topics: Acetylcholine; Adenoma, Islet Cell; Animals; Blood Glucose; Glucagon; Glucose; Insulin; Insulinoma; | 1984 |
Insulinoma.
Topics: Adenoma, Islet Cell; Animals; Humans; Male; Pancreatic Function Tests; Pancreatic Neoplasms; Tolbuta | 1980 |
Use of an extracorporeal glucose monitor for the diagnosis and surgical treatment of an insulinoma.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Extracorporeal Circulation; Glucose; Humans; Insulin; Mal | 1980 |
[A case of insulinoma].
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Humans; Hypoglycemia; Insulin; Male; Pancreatic Neoplasms | 1980 |
A case with glucagonoma syndrome--endocrine and metabolic studies.
Topics: Adenoma, Islet Cell; C-Peptide; Endocrine Glands; Female; Glucagon; Glucagonoma; Glucose Tolerance T | 1981 |
Plasma insulin response to various secretagogues in insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Arginine; Blood Glucose; Child; Fasting; Female; Glucagon; Glucose | 1982 |
[Insulin-producing tumor of the pancreas].
Topics: Adenoma, Islet Cell; Adult; Diagnosis, Differential; Fasting; Humans; Hypoglycemia; Insulinoma; Male | 1982 |
Analysis of insulin secretion based on changes in plasma insulin and C-peptide in man.
Topics: Adult; Aged; Arginine; C-Peptide; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Human | 1982 |
Is reactive hypoglycemia a clinical entity?
Topics: Blood Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Pancreatic Neoplasms; Terminology as To | 1983 |
Ca2+/calmodulin-dependent protein kinase II and synapsin I-like protein in mouse insulinoma MIN6 cells.
Topics: Animals; Autoradiography; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Electrophoresis, Po | 1995 |
Dissociation of KATP channel and sulphonylurea receptor in the rat clonal insulin-secreting cell line, CRI-D11.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cel | 1993 |
Bimodal effect of transforming growth factor-beta on insulin secretion in MIN6 cells.
Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Glucose; Humans; Insulin; Insulin Secretion; I | 1994 |
Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Diazoxide; Glucagon; Glucagono | 1993 |
Enhanced stimulus-secretion coupling in polyamine-depleted rat insulinoma cells. An effect involving increased cytoplasmic Ca2+, inositol phosphate generation, and phorbol ester sensitivity.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Carbachol; Cytoplasm; Diazoxide; DNA, Ne | 1993 |
Glucose-induced [Ca2+]i oscillations in single human pancreatic islets.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biological Transport; Calcium; Cells, Cultured; Diaz | 1996 |
Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Deoxyglucose; Enzyme Activation; E | 1997 |
RIN14B: a pancreatic delta-cell line that maintains functional ATP-dependent K+ channels and capability to secrete insulin under conditions where it no longer secretes somatostatin.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diazoxide; Electrophysiology; Insulin; Insul | 1997 |
Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C.
Topics: Animals; Calcium; Enzyme Activation; Exocytosis; Glyburide; Guanosine 5'-O-(3-Thiotriphosphate); Hyp | 1998 |
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; C | 1999 |
Glibenclamide but not other sulphonylureas stimulates release of neuropeptide Y from perifused rat islets and hamster insulinoma cells.
Topics: Animals; Blotting, Northern; Cricetinae; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; | 2000 |
The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.
Topics: 1-Methyl-3-isobutylxanthine; 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potenti | 2001 |
Interaction of sulfonylurea-conjugated polymer with insulinoma cell line of MIN6 and its effect on insulin secretion.
Topics: Acrylic Resins; Animals; Biocompatible Materials; Culture Media, Conditioned; Diazoxide; Glucose; Gl | 2001 |
Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Carrier Proteins; Cytosol; Gene Expression Regulation, Neo | 2002 |
[Experience in the treatment of islet adenomas (author's transl)].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Blood Glucose; Brain Damage, Chronic; Child; Female; F | 1976 |
Familial islet-cell adenomatosis.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diabetes Complications; Female; Glucagon; HLA Antigens; H | 1977 |
Somatostatin-tolbutamide test in hyperinsulinism due to beta-cell hyperplasia.
Topics: Adenoma, Islet Cell; Humans; Hyperinsulinism; Hyperplasia; Insulin; Islets of Langerhans; Pancreatic | 1978 |
Somatostatin-tolbutamide test in hyperinsulinism.
Topics: Adenoma, Islet Cell; Humans; Insulin; Insulin Secretion; Pancreatic Neoplasms; Paraneoplastic Endocr | 1978 |
Somatostatin-tolbutamide test: A reliable test for hyperinsulinism?
Topics: Adenoma; Diagnosis, Differential; Drug Evaluation; Humans; Hyperinsulinism; Pancreatic Neoplasms; So | 1978 |
Plasma pancreatic hormone levels in a case of somatostatinoma: diagnostic and therapeutic implications.
Topics: C-Peptide; Diabetes Complications; Female; Glucagon; Humans; Middle Aged; Pancreatic Neoplasms; Panc | 1979 |
Hypoglycemia: a perspective.
Topics: Adenoma, Islet Cell; Citric Acid Cycle; Diabetes Complications; Diazoxide; Female; Glucose; Glucose | 1975 |
[Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)].
Topics: Adenoma, Islet Cell; Amides; Animals; Blood Glucose; Cats; Cystine; Deoxyglucose; Diabetes Mellitus; | 1975 |
Diagnostic value of intravenous glucagon test in insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Arginine; Child; Evaluation Studies as Topic; Female; Glucagon; Gl | 1975 |
Inhibition by somatostatin of tolbutamide-induced insulin secretion in a patient with an insulinoma.
Topics: Adenoma, Islet Cell; Aged; Humans; Insulin; Male; Pancreatic Neoplasms; Somatostatin; Tolbutamide | 1976 |
Somatostatin inhibition of insulin secretion in insulin-producing tumors.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Depression, Chemical; Female; Glucagon; Glucose; Growth H | 1976 |
Insulinoma: clinical and diagnostic features of 60 consecutive cases.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Blood Glucose; Diagnostic Errors; Electroencephalograp | 1976 |
[Angiographic diagnosis of pancreatic insulomas: proposed original method for image enhancement].
Topics: Adenoma, Islet Cell; Angiography; Glucose Solution, Hypertonic; Hepatic Artery; Humans; Injections, | 1975 |
[Angiography of the pancreas after pharmocologic stimulation].
Topics: Adenoma, Islet Cell; Glucose; Humans; Pancreas; Pancreatic Neoplasms; Radiography; Tolbutamide | 1975 |
Immunoreactive insulin in portal and hepatic venous blood in patients with insuloma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Female; Glucose; Hepatic Veins; Humans; Insulin; Ma | 1976 |
Hyperinsulinemic hypoglycemia: effect of epinephrine suppression.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Carcinoma; Epinephrine; Female; Humans; Hyperinsulinism; Hyperp | 1977 |
[The insulinomas].
Topics: Adenoma, Islet Cell; Diazoxide; Glucagon; Humans; Hyperplasia; Insulin; Insulin Secretion; Pancreati | 1979 |
[Tolbutamide loading test].
Topics: Adenoma, Islet Cell; Blood Glucose; Diagnosis, Differential; Humans; Hyperglycemia; Insulin; Pancrea | 1979 |
[Methods of laboratory and function tests in the diagnosis of insulin-secreting islet cell tumor].
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Humans; Insulin; Insulin Secretion; Methods; Pancre | 1979 |
The use of artificial beta cell in diagnosis and treatment of insulinoma.
Topics: Adenoma, Islet Cell; Adult; Artificial Organs; Blood Glucose; C-Peptide; Feedback; Female; Humans; I | 1979 |
Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Hyperglycemia; Insulin; Insul | 1991 |
Effects of alanine on insulin-secreting cells: patch-clamp and single cell intracellular Ca2+ measurements.
Topics: Alanine; Animals; Calcium; Cell Membrane; Glucose; Insulin; Insulin Secretion; Insulinoma; Kinetics; | 1990 |
Structure, function, and immunogenicity of human insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Adult; C-Peptide; Fluorescent Antibody Technique; | 1988 |
Diagnostic interpretation of the intravenous tolbutamide test for insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Body Weight; Evaluation Studies as Topic; Female; Glucose Tolera | 1989 |
Diagnosis and differential diagnosis of hypoglycemia.
Topics: Blood Glucose; Diagnosis, Differential; False Positive Reactions; Glucose Tolerance Test; Humans; Hy | 1989 |
Biosynthesis of insulin secretory granule membrane proteins. Control by glucose.
Topics: Adenoma, Islet Cell; Animals; Calcium; Chemical Precipitation; Cytoplasmic Granules; Glucose; Immuno | 1987 |
Comparative diagnostic value of the calcium-pentagastrin test versus the tolbutamide test in a patient with a somatostatinoma.
Topics: Adenoma, Islet Cell; Calcium; Female; Humans; Middle Aged; Pancreatic Neoplasms; Pentagastrin; Somat | 1987 |
[Studies on the diagnosis of insulinoma].
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Blood Glucose; C-Peptide; Female; Glucagon; Humans; In | 1987 |
Inhibition of insulin release by diphenylhydantoin and diazoxide in a patient with benign insulinoma.
Topics: Adenoma, Islet Cell; Aged; Depression, Chemical; Diazoxide; Glucose; Humans; Insulin; Insulin Secret | 1973 |
Biochemical studies in a patient with hyperinsulinism.
Topics: Adenoma, Islet Cell; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hydrocortisone; Hyperi | 1966 |
Insulin-secreting islet-cell tumours of the pancreas.
Topics: Adenoma, Islet Cell; Adult; Duodenum; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leuc | 1967 |
Definitive diagnosis of insulin-secreting tumors of the pancreas.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Female; Humans; Insulin; Middle Aged; Pancreatic Neoplasm | 1967 |
Insulin secretion by insuloma and normal pancreas slices. Studies in a patient with multiple endocrine adenomata.
Topics: Adenoma; Adenoma, Islet Cell; Adult; Female; Glucose; Glucose Tolerance Test; Humans; In Vitro Techn | 1968 |
[Current methods of study and morphologic findings in B-cell adenoma of the pancreas].
Topics: Adenoma, Islet Cell; Adolescent; Blood Glucose; Diagnosis, Differential; Female; Glucose Tolerance T | 1967 |
[Insulinoma].
Topics: Adenoma, Islet Cell; Adult; Humans; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; | 1968 |
[Diagnosis and therapy of islet cell adenomas].
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Female; Humans; Insulin; Male; Middle Aged; Pancrea | 1969 |
[On the clinical diagnosis of islet cell adenoma. Clinical experiences and diagnostic procedure in organic hyperinsulism].
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diagnosis, Differential; Electroencephalography; Female; | 1969 |
Functioning beta slet cell tumors. Preoperative tests and surgical approach.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Female; Humans; Insulin; Male; Pancreatic Neoplasms | 1969 |
Islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Aged; Fasting; Female; Humans; Hypoglycemia; Insulin; Leucine; Male; Middle Age | 1969 |
Plasma insulin studies in the diagnosis of insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Female; Glucagon; Glucose Tolerance Test; Humans; I | 1969 |
Clinical experience with human growth hormone immunoassay by a two-antibody method.
Topics: Acromegaly; Adenoma, Chromophobe; Adenoma, Islet Cell; Amenorrhea; Anorexia Nervosa; Arginine; Dwarf | 1969 |
Plasma insulin: fluctuations in the "big" insulin component in man after glucose and other stimuli.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Arginine; Fasting; Female; Glucose; Glucose Tole | 1969 |
Planning the appropriate operations for islet cell tumors of the pancreas.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Glucose Tolerance Test; Humans; Leucine; Neoplasm M | 1970 |
Blood sugar, serum insulin and free fatty acid interrelationships during intravenous tolbutamide testing in normal young adults and in patients with insulinoma.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Age Factors; Blood Glucose; Body Height; Body Weight; Diabet | 1970 |
Medical grand rounds at Yale-New Haven Hospital. Diagnosis and management of hypoglycemia.
Topics: Adenoma, Islet Cell; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Leucine; Pancreatic Neop | 1970 |
[A transplantable insuloma of the Syrian hamster Mesocricetus auratus auratus. Review of its properties and of its effects on the host].
Topics: Adenoma, Islet Cell; Animals; Blood Glucose; Body Weight; Carbon Isotopes; Cricetinae; Fasting; Gluc | 1968 |
[Clinical and radiological diagnosis of hyperinsulinism].
Topics: Adenoma, Islet Cell; Celiac Artery; Diagnosis, Differential; Fasting; Female; Humans; Hyperinsulinis | 1969 |
[Insulinoma in aged patients].
Topics: Adenoma, Islet Cell; Age Factors; Aged; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglyce | 1968 |
Proinsulin secretion by a pancreatic beta-cell adenoma. Proinsulin and C-peptide secretion.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Chromatography, Gel; Female; Humans; Immune Sera; Immunoa | 1970 |
Islet cell tumor with hypoglycemia.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperinsul | 1971 |
[2 cases of Langerhans adenoma].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Islet Cell; Adult; Aged; Angiography; Celiac Ar | 1969 |
Circulating proinsulin-like material in patients with functioning insulinomas.
Topics: Adenoma, Islet Cell; Chromatography, Gel; Electrophoresis; Glucose Tolerance Test; Humans; Hypoglyce | 1971 |
Insulin and growth hormone regulation in organic hyperinsulinism.
Topics: Adenoma, Islet Cell; Adolescent; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; | 1971 |
Islet cell adenomatosis and adenoma in an infant.
Topics: Adenoma, Islet Cell; Adrenocorticotropic Hormone; Diazoxide; Glucose; Humans; Hypoglycemia; Infant, | 1971 |
Factitious hypoglycemia. Why not diagnose before laparotomy?
Topics: Adenoma, Islet Cell; Adult; Antibodies; Diabetes Mellitus; Diagnosis, Differential; Glucose Toleranc | 1971 |
Surgical grand rounds from the University of Mississippi Medical Center. Management of hyperinsulinism.
Topics: Adenoma, Islet Cell; Diagnosis, Differential; Diazoxide; Dietary Carbohydrates; Female; Glucose Tole | 1971 |
Insulinoma of the pancreas. Use of the tolbutamide test, arteriography, and selenium scan in modern diagnosis.
Topics: Adenoma, Islet Cell; Adult; Aged; Angiography; Celiac Artery; Female; Glucose Tolerance Test; Humans | 1972 |
Insulin and glucose patterns in control subjects and in proved insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Child; False Negative Reactions; Fasting; Female; G | 1971 |
Beta cell adenoma in a child with hypoglycemia controlled with diazoxide.
Topics: Adenoma, Islet Cell; Blood Glucose; Child, Preschool; Diazoxide; Female; Glucose Tolerance Test; Hum | 1972 |
Different serum insulin patterns in portal, hepatic and peripheral venous blood in two cases of insuloma.
Topics: Adenoma, Islet Cell; Aged; Blood Glucose; Female; Glucose Tolerance Test; Hepatic Veins; Humans; Imm | 1972 |
[Secreting langerhansian insulinoma. Clinical, biological, arteriographical and ultrastructural study of a case].
Topics: Adenoma, Islet Cell; Adolescent; Angiography; Blood Glucose; Female; Glucose Tolerance Test; Humans; | 1971 |
Pancreatic islet beta cell tumors and hyperplasia: experience in 14 Seattle hospitals.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Child; Diazoxide; Female; Humans; Hyperinsulinism; Hyp | 1972 |
[Surgery of insulomas].
Topics: Adenoma, Islet Cell; Adult; Female; Humans; Methionine; Middle Aged; Pancreatic Neoplasms; Radioisot | 1972 |
Insulinoma diagnosed by insulin immunoassay and angiography.
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Child; Humans; Hypoglycemia; Immunoassay; Insulin; | 1972 |
Clinical use of radioimmunological plasma insulin assessment.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diet; Glucose Toleranc | 1973 |
Various tests in the evaluation of islet cell adenomas.
Topics: Adenoma, Islet Cell; Blood Glucose; Fasting; Glucagon; Humans; Insulin; Leucine; Male; Middle Aged; | 1973 |
[Insulinoma: report of 2 cases and classification of hypoglycemia].
Topics: Adenoma, Islet Cell; Adolescent; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Male; Middle | 1973 |
Streptozotocin for malignant insulinomas and carcinoid tumor. Report of eight cases and review of the literature.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Carcinoid Tumor; Chemical and Drug Induced Liver Injury; | 1973 |
[Functioning beta-insular tumors of the pancreas. Principal diagnostic tests].
Topics: Adenoma, Islet Cell; Aortography; Blood Glucose; Fasting; Glucose Tolerance Test; Humans; Leucine; M | 1973 |
2,3-Diphosphoglycerate fluctuations in erythrocytes reflecting pronounced blood glucose variation. In-vivo and in-vitro studies in normal, diabetic and hypoglycaemic subjects.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diabetes Mellitus; Diphosphoglyceric Acids; Erythrocytes; | 1973 |
Diagnostic and surgical aspects of insulinoma. A review of twenty-seven cases.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Angiography; Blood Glucose; Child; Child, Preschool; D | 1974 |
Proceedings: Arteriography in insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Angiography; Blood Glucose; Celiac Artery; Female; Humans; Hypogly | 1974 |
[Exploration of hypoglycemia].
Topics: Adenoma, Islet Cell; Arginine; Blood Glucose; Diazoxide; Diet; Fasting; Glucagon; Hormones, Ectopic; | 1974 |
Diagnostic use of glucagon-induced insulin response. Studies in patients with insulinoma or other hypoglycemic conditions.
Topics: Adenoma, Islet Cell; Adult; Aged; Blood Glucose; Carcinoma, Hepatocellular; Child; Diagnosis, Differ | 1974 |
Hypoglycemia and insular hyperplasia: review of 148 cases.
Topics: Adenoma, Islet Cell; Adult; Age Factors; Blood Glucose; Child; Diagnosis, Differential; Epilepsy; Fa | 1974 |
[Atypical case of insulinoma (author's transl)].
Topics: Adenoma, Islet Cell; Angiography; Blood Glucose; Fasting; Female; Glucose Tolerance Test; Humans; Hy | 1974 |
Nesidioblastosis in familial endocrine adenomatosis.
Topics: Adrenal Gland Neoplasms; Adult; Child; Gastrins; Glucagon; Glucose Tolerance Test; Humans; Insulin; | 1969 |
Carbohydrate tolerance and insulin responses in obstructive jaundice.
Topics: Aged; Blood Glucose; Cholestasis; Diagnosis, Differential; Female; Glucagon; Glucose Tolerance Test; | 1974 |
[Editorial: Hypoglycemic digestive tumors].
Topics: Cystadenoma; Gastrointestinal Neoplasms; Hormones, Ectopic; Humans; Hypoglycemia; Insulin; Insulin S | 1973 |
[Hypoglycemia].
Topics: Child; Dietary Carbohydrates; Epinephrine; Gastrointestinal Hormones; Glucagon; Gluconeogenesis; Glu | 1973 |
Hyperinsulinism in dogs with neoplasia of the pancreatic islets. A clinical, pathologic, and ultrastructural study.
Topics: Adenoma; Animals; Blood Glucose; Carcinoma; Dog Diseases; Dogs; Glucose Tolerance Test; Hyperinsulin | 1969 |
[Primary and secondary hyperinsulinism].
Topics: Acromegaly; Cushing Syndrome; Diabetes Complications; Glucagon; Glucose Tolerance Test; Humans; Hype | 1970 |
Insulin secretion after tolbutamide and after secretin in patients with pancreatic diseases.
Topics: Adolescent; Adult; Aged; Amylases; Blood Glucose; Calcinosis; Cystic Fibrosis; Duodenum; Feces; Fema | 1972 |
[On the use of the tolbutamide test in pancreatic carcinoma].
Topics: Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diagnosis, Differential; Female; Humans; I | 1967 |
[Functional exploration of insulin secretion in sponteaneous hypoglycemia].
Topics: Adenoma; Arginine; Glucagon; Glucose; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secret | 1967 |
[Hypoglycemia factitia. A differential diagnostic significant form of hyperinsulinism].
Topics: Adolescent; Diabetes Mellitus, Type 1; Diabetic Coma; Diagnosis, Differential; Female; Humans; Hyper | 1969 |
[Tolbutamide tests in children].
Topics: Adenoma; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diagnosis, Differential; | 1965 |
[Experiences with the Orabet test in pancreatic diseases].
Topics: Humans; Injections, Intravenous; Liver Diseases; Pancreatic Diseases; Pancreatic Neoplasms; Tolbutam | 1965 |
[The use of the tolbutamide test in the diagnosis of obstructive jaundices].
Topics: Adult; Aged; Blood Glucose; Cholelithiasis; Cholestasis; Diagnosis, Differential; Female; Humans; Ma | 1966 |