tolbutamide has been researched along with Brain Ischemia in 4 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bancila, V | 1 |
| Nikonenko, I | 1 |
| Dunant, Y | 1 |
| Bloc, A | 1 |
| Murai, Y | 1 |
| Ishibashi, H | 1 |
| Koyama, S | 1 |
| Akaike, N | 1 |
| Calabresi, P | 1 |
| Marfia, GA | 1 |
| Centonze, D | 1 |
| Pisani, A | 1 |
| Bernardi, G | 1 |
| Kulik, A | 1 |
| Trapp, S | 1 |
| Ballanyi, K | 1 |
4 other studies available for tolbutamide and Brain Ischemia
| Article | Year |
|---|---|
Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Brain Ischemia; Chelating Agents; Chlorocebus aethiops; | 2004 |
Ca2+-activated K+ currents in rat locus coeruleus neurons induced by experimental ischemia, anoxia, and hypoglycemia.
Topics: Animals; Brain Ischemia; Calcium; Calcium Channels; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazo | 1997 |
Sodium influx plays a major role in the membrane depolarization induced by oxygen and glucose deprivation in rat striatal spiny neurons.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Channels | 1999 |
Ischemia but not anoxia evokes vesicular and Ca(2+)-independent glutamate release in the dorsal vagal complex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Brain | 2000 |