tolbutamide has been researched along with Blood Pressure, High in 38 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia." | 7.65 | Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972) |
| "Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment." | 7.65 | Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971) |
| "Treatment with oral diazoxide for periods of 4 to 10 weeks in hospital allowed adequate control of hypertension with continuation of fetal growth in four patients with severe toxaemia." | 3.65 | Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy. ( Davis, D; Morgan, MY; Pohl, JE; Thurston, H, 1972) |
| "Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment." | 3.65 | Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (89.47) | 18.7374 |
| 1990's | 4 (10.53) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GELFAND, M | 1 |
| FORBES, JI | 1 |
| SCHWARTZ, W | 1 |
| WOLFF, FW | 1 |
| LANGDON, RG | 1 |
| FABRYKANT, M | 1 |
| GELFAND, ML | 1 |
| ROSENBERG, AS | 1 |
| Dieterle, P | 2 |
| Fehm, H | 2 |
| Ströder, W | 2 |
| Henner, J | 2 |
| Bottermann, P | 2 |
| Schwarz, K | 2 |
| Ziegelasch, HJ | 1 |
| Ziegelasch, H | 1 |
| Mauve, L | 1 |
| Tötterman, KJ | 1 |
| Groop, LC | 1 |
| Deng, LY | 1 |
| Li, JS | 1 |
| Schiffrin, EL | 1 |
| Kau, ST | 1 |
| Zografos, P | 1 |
| Do, ML | 1 |
| Halterman, TJ | 1 |
| McConville, MW | 1 |
| Yochim, CL | 1 |
| Trivedi, S | 1 |
| Howe, BB | 1 |
| Li, JH | 1 |
| Ferrara, A | 1 |
| Wijdeveld, P | 1 |
| Koene, R | 1 |
| Buchanan, TA | 1 |
| Youn, JH | 1 |
| Campese, VM | 1 |
| Sipos, GF | 1 |
| Dzúrik, R | 1 |
| Dzúriková, K | 1 |
| Spustová, V | 1 |
| Koev, D | 1 |
| Borisova, AM | 1 |
| Zlatareva, N | 1 |
| Kirilov, G | 1 |
| Ryan, JR | 1 |
| Podolsky, S | 1 |
| Pattavina, CG | 1 |
| Catellier, C | 1 |
| Ringuet, J | 1 |
| Rivière, L | 1 |
| Plamondon, C | 1 |
| Finnerty, FA | 1 |
| Tanaka, N | 1 |
| Takenouchi, A | 1 |
| Trautwein, H | 3 |
| Julitz, R | 3 |
| Prout, TE | 1 |
| Pohl, JE | 2 |
| Thurston, H | 2 |
| Davis, D | 1 |
| Morgan, MY | 1 |
| Constam, GR | 1 |
| Keen, H | 1 |
| Juhl, F | 1 |
| Persson, I | 2 |
| Schwarzbach, W | 1 |
| Möller, E | 1 |
| Klein, B | 1 |
| Andersen, OO | 1 |
| Krecke, HJ | 1 |
| Timmler, R | 1 |
| Betzien, G | 1 |
| Hanusch, AW | 1 |
| Kaiser, G | 1 |
| Lenti, G | 1 |
| Pellegrini, A | 1 |
| Pagano, G | 1 |
| Porrazzo, G | 1 |
| Brotzu, M | 1 |
| Srivastava, SC | 1 |
| Singh, A | 1 |
| Arora, BS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective, Parallel Goups Study, Aimed to Evaluating Possible Benefits of the Treatment of New Generation Hypoglycaemic Drugs Compared to Sulphonylureas for the Tratment of Type 2 Diabetes Mellitus[NCT04272359] | 138 participants (Anticipated) | Observational [Patient Registry] | 2019-05-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for tolbutamide and Blood Pressure, High
| Article | Year |
|---|---|
No effect of propranolol and metoprolol on tolbutamide-stimulated insulin-secretion in hypertensive diabetic and non-diabetic patients.
Topics: Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Hu | 1982 |
The University Group Diabetes Program. A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. V. Evaluation of pheniformin therapy.
Topics: Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Clinical Tri | 1975 |
A prospective view of the treatment of adult-onset diabetes with special reference to the University Group Diabetes Program and oral hypoglycemic agents.
Topics: Angina Pectoris; Blood Glucose; Clinical Trials as Topic; Creatinine; Diabetes Complications; Diabet | 1971 |
Carbohydrate metabolism during treatment with chlorthalidone and ethacrynic acid.
Topics: Aged; Blood Glucose; Carbohydrate Metabolism; Chlorthalidone; Cortisone; Diabetes Mellitus; Ethacryn | 1968 |
34 other studies available for tolbutamide and Blood Pressure, High
| Article | Year |
|---|---|
DIABETES MELLITUS IN THE RHODESIAN AFRICAN.
Topics: Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Coma; Diabetic | 1963 |
MEBUTAMATE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION.
Topics: Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure Determination; Carbamates; | 1964 |
CONJOINT CLINIC ON DRUGS AND DIABETES.
Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose | 1964 |
FURTHER EXPERIENCE WITH ANABOLIC STEROIDS IN DIABETIC RETINOPATHY: FACTORS PRECIPITATING RETINAL HEMORRHAGES.
Topics: Diabetic Nephropathies; Diabetic Retinopathy; Diet, Diabetic; Drug Therapy; Estrogens; Geriatrics; H | 1964 |
[Asymptomatic diabetes mellitus in normal weight subjects with hypertension. Studies on glucose tolerance, serum insulin and nonesterified fatty acids in essential hypertension].
Topics: Blood Glucose; Body Weight; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose Tolerance Test; H | 1967 |
[Incidence of pathological ECG findings, hypertension and obesity in diabetic patients depending on their mode of therapy].
Topics: Cardiomegaly; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Electrocardiograph | 1981 |
Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats.
Topics: Acetylcholine; Adult; Animals; Apamin; Arginine; Arterioles; Charybdotoxin; Endothelium, Vascular; H | 1995 |
Characterization of ATP-sensitive potassium channel-blocking activity of ZENECA ZM181,037, a eukalemic diuretic.
Topics: Acetamides; Adenosine Triphosphate; Administration, Oral; Animals; Benzopyrans; Blood Glucose; Blood | 1994 |
[Effect of prolonged nicotinic acid load on the tolbutamide test].
Topics: Aged; Blood Glucose; Diabetes Mellitus; Endarteritis; Female; Humans; Hyperglycemia; Hypertension; H | 1979 |
A study of the effects of hypoglycemia agents on vascular complications in patients with adult-onset diabetes. VI. Supplementary report on nonfatal events in patients treated with tolbutamide.
Topics: Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic | 1976 |
[Diazoxide: new way in treatment of hypertension].
Topics: Adult; Chlorthalidone; Diazoxide; Diet, Sodium-Restricted; Female; Humans; Hydralazine; Hypertension | 1975 |
Enhanced glucose tolerance in spontaneously hypertensive rats. Pancreatic beta-cell hyperfunction with normal insulin sensitivity.
Topics: 3-O-Methylglucose; Animals; Blood Glucose; Glucose Tolerance Test; Hypertension; Insulin; Insulin Se | 1992 |
[Improvement in glucose tolerance and insulin sensitivity after a single administration of tolbutamide in hypertensive patients].
Topics: Blood Glucose; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin; Insulin Resistance; Ma | 1991 |
[Effect of antihypertensive drugs on insulin secretion and efficacy].
Topics: Adult; Aged; Antihypertensive Agents; C-Peptide; Diabetes Mellitus, Type 2; Drug Evaluation; Drug In | 1989 |
Clinical pharmacology of acebutolol.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Digoxin; Drug Interactions; Female; Humans; Hy | 1985 |
Hyperosmolar nonketotic diabetic coma: a complication of propranolol therapy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Diabetes Complications; Diabetes Mellitus; Diabet | 1973 |
[Insulinoma in aged patients].
Topics: Adenoma, Islet Cell; Age Factors; Aged; Female; Glucagon; Glucose Tolerance Test; Humans; Hyperglyce | 1968 |
Hypertensive crisis.
Topics: Acute Disease; Cerebrovascular Circulation; Cerebrovascular Disorders; Diagnosis, Differential; Diaz | 1974 |
[A case of acute erythremia occurring during treatment of diabetes and hypertension].
Topics: Chlorothiazide; Diabetes Complications; Diabetes Mellitus; Humans; Hydroflumethiazide; Hypertension; | 1972 |
[Diabetic metabolism and arteriosclerosis].
Topics: Adult; Aged; Arteries; Arteriosclerosis; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopa | 1973 |
Successful use of oral diazoxide in the treatment of severe toxaemia of pregnancy.
Topics: Acute Disease; Administration, Oral; Adult; Albuminuria; Blood Glucose; Diazoxide; Female; Furosemid | 1972 |
Is the use of sulphonylurea derivatives in the treatment of diabetes mellitus dangerous?
Topics: Adult; Aged; Autopsy; Diabetes Complications; Diabetes Mellitus; Diet Therapy; Drug Synergism; Femal | 1971 |
Use of diazoxide in hypertension with renal failure.
Topics: Adolescent; Adult; Blood Glucose; Creatine; Diazoxide; Dietary Proteins; Female; Humans; Hyperglycem | 1971 |
Factors influencing the progress of atherosclerosis in the diabetic.
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Child; Diabetes Mellitus; Diabetic Angiopathies; Female; | 1971 |
[Carbohydrate metabolism during treatment with chlorthalidone and cyclothiazide].
Topics: Aged; Antihypertensive Agents; Benzothiadiazines; Carbohydrate Metabolism; Chlorthalidone; Cortisone | 1970 |
[Extracellular potassium concentration and fasting blood sugar in diabetes mellitus].
Topics: Biological Transport; Blood Glucose; Cell Membrane Permeability; Diabetes Mellitus; Diuretics; Extra | 1970 |
[Heart infarct and subclinical diabetes].
Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Diabetes Complications; Female; Humans; Hyperte | 1970 |
[Myocardial infarct, diabetic metabolism and lipid value].
Topics: Adult; Aged; Blood Glucose; Cholesterol; Diabetes Complications; Diabetes Mellitus; Diagnosis, Diffe | 1967 |
[Clinical experience with a new spironolactone-thiabuzide combination].
Topics: Aged; Body Weight; Digoxin; Diuretics; Drug Synergism; Edema; Female; Furosemide; Glycosuria; Humans | 1968 |
Asymptomatic diabetes mellitus in hypertensive patients of normal weight. Glucose tolerance and serum levels of insulin and nonesterified fatty acids in essential hypertension.
Topics: Adult; Blood Glucose; Body Weight; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose Tolerance | 1968 |
[Studies of latent diabetes mellitus].
Topics: Adult; Aged; Blood Glucose; Cortisone; Diabetes Mellitus; Diagnosis, Differential; Female; Glucose; | 1969 |
[Early diagnosis of diabetes mellitus by means of the tolbutamide test, especially in adipose, hypertensive and cardiovascular patients].
Topics: Diabetes Mellitus; Humans; Hypertension; Myocardial Infarction; Obesity; Tolbutamide | 1966 |
[Familial aspects of the relations between diabetes mellitus and cardiovascular diseases. Clinico-experimental research].
Topics: Adult; Coronary Disease; Cryoglobulins; Diabetes Complications; Diabetes Mellitus; Female; Glucose T | 1966 |
Chemical and latent chemical diabetes in myocardial infarction, cerebral thrombosis and hypertension.
Topics: Adult; Aged; Diabetes Complications; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hype | 1966 |