tolbutamide has been researched along with Autoimmune Diabetes in 131 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Isolated rat islets were incubated in the presence of immunoglobulin preparations from patients with insulin-dependent and non-insulin-dependent diabetes mellitus (IDDM, NIDDM) and healthy subjects, and stimulated with D-glucose, L-arginine or tolbutamide." | 3.68 | Islet cell surface antibodies preferentially inhibit glucose-stimulated insulin release in vitro. ( Kajiyama, S; Kanatsuna, T; Kano, Y; Kitagawa, Y; Kondo, M; Ludvigsson, J; Nakamura, N; Nakamura, Y; Nakano, K, 1990) |
| "Tolbutamide was shown to have no independent effect on VLDL TG or VLDL apo B production in four insulin-deficient diabetic subjects." | 1.29 | VLDL production is decreased to a similar extent by acute portal vs. peripheral venous insulin. ( Lewis, GF; Steiner, G; Szeto, L; Uffelman, KD; Weller, B; Zinman, B, 1994) |
| "Basal values of T increased in both T-IDDM and T-NIDDM, compared to IDDM and NIDDM, respectively." | 1.28 | Chronic effects of tolbutamide on myocardial tension during ischemia and reperfusion in perfused hearts isolated from insulin dependent and non insulin dependent diabetic rats. ( Mimura, G; Murakami, K; Oshiro, K; Sunagawa, R, 1991) |
| "SI was normalized in IDDM in clinical remission despite a continued poor insulin secretory response to both glucose and tolbutamide." | 1.28 | A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes. ( Dupre, J; Finegood, DT; Hramiak, IM, 1990) |
| "No increase was noted in patients with Type 2 diabetes or with IGT." | 1.28 | Basal and tolbutamide-induced plasma somatostatin in healthy subjects and in patients with diabetes and impaired glucose tolerance. ( De Vroede, M; Michotte, Y; Segers, O; Somers, G, 1989) |
| "With overt IDDM, insulin levels are low and unresponsive." | 1.27 | Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat. ( Marliss, EB; Nakhooda, AF; Poussier, P, 1983) |
| "tolbutamide was significantly enhanced compared to the C-peptide secretion observed during arginine infusion alone." | 1.27 | The effect of glucose, tolbutamide, and arginine on C-peptide release during remission in type I diabetes mellitus. ( Beischer, W; Heinze, E; Teller, W; Thon, A; Vetter, U, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 111 (84.73) | 18.7374 |
| 1990's | 15 (11.45) | 18.2507 |
| 2000's | 5 (3.82) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FABRYKANT, M | 3 |
| BERTO, R | 1 |
| ASHE, BI | 1 |
| DI GEORGE, AM | 1 |
| CHIOWANICH, P | 1 |
| HOSTOMSKA, L | 1 |
| KLASCHKOVA, J | 1 |
| SEJDOVA, E | 1 |
| LESTRADET, H | 1 |
| ROYER, P | 1 |
| BOSCHERINI, B | 1 |
| HAUGEN, HN | 1 |
| MOSS, JM | 1 |
| DELAWTER, DE | 1 |
| GALLAGHER, EJ | 1 |
| KEEN, H | 1 |
| RUVALCABA, RH | 1 |
| SAMOLS, E | 1 |
| KELLEY, VC | 1 |
| KAYE, R | 3 |
| DAVIDSON, MH | 1 |
| Koster, JC | 2 |
| Remedi, MS | 1 |
| Dao, C | 1 |
| Nichols, CG | 2 |
| Masia, R | 1 |
| Tumini, S | 1 |
| Chiarelli, F | 1 |
| Colombo, C | 1 |
| Barbetti, F | 1 |
| Babenko, AP | 1 |
| Ivancho, ES | 1 |
| de Belle, R | 1 |
| Belmonte, MM | 1 |
| Colle, E | 2 |
| Baker, L | 2 |
| Root, AW | 1 |
| Ratzmann, KP | 1 |
| Schulz, B | 1 |
| Heinke, P | 1 |
| Besch, W | 1 |
| Traeger, J | 1 |
| Dubernard, JM | 1 |
| Pozza, G | 3 |
| Secchi, A | 1 |
| Bosi, E | 1 |
| Pontiroli, AE | 2 |
| Gelet, A | 1 |
| Martin, X | 1 |
| Touraine, JL | 1 |
| Marliss, EB | 1 |
| Nakhooda, AF | 1 |
| Poussier, P | 1 |
| Vetter, U | 1 |
| Heinze, E | 1 |
| Thon, A | 1 |
| Beischer, W | 1 |
| Teller, W | 1 |
| Ganda, OP | 2 |
| Srikanta, S | 1 |
| Brink, SJ | 1 |
| Morris, MA | 1 |
| Gleason, RE | 3 |
| Soeldner, JS | 3 |
| Eisenbarth, GS | 1 |
| Tripathy, BB | 1 |
| Samal, KC | 1 |
| Murty, VK | 1 |
| Misra, PK | 1 |
| Parida, RK | 1 |
| Alberetto, M | 1 |
| Bertoletti, A | 1 |
| Baio, G | 1 |
| Mirel, RD | 1 |
| Ginsberg-Fellner, F | 1 |
| Horwitz, DL | 1 |
| Rayfield, EJ | 1 |
| Verlohren, HJ | 2 |
| Lohmann, D | 2 |
| Widness, JA | 1 |
| Cowett, RM | 1 |
| Zeller, WP | 1 |
| Susa, JB | 1 |
| Rubenstein, AH | 1 |
| Schwartz, R | 1 |
| Dreyer, M | 1 |
| Kühnau, J | 1 |
| Rüdiger, HW | 1 |
| Quon, MJ | 1 |
| Cochran, C | 1 |
| Taylor, SI | 1 |
| Eastman, RC | 1 |
| Streckfus, CF | 1 |
| Marcus, S | 1 |
| Welsh, S | 1 |
| Brown, RS | 1 |
| Cherry-Peppers, G | 1 |
| Brown, RH | 1 |
| Lewis, GF | 4 |
| Zinman, B | 3 |
| Uffelman, KD | 1 |
| Szeto, L | 1 |
| Weller, B | 2 |
| Steiner, G | 2 |
| Christiansen, E | 2 |
| Tibell, A | 2 |
| Võlund, A | 1 |
| Rasmussen, K | 2 |
| Tydén, G | 2 |
| Pedersen, O | 1 |
| Christensen, NJ | 1 |
| Madsbad, S | 2 |
| Polonsky, KS | 1 |
| Osei, K | 2 |
| Henry, M | 1 |
| Ferguson, R | 1 |
| Williams, AJ | 1 |
| Beales, PE | 1 |
| Krug, J | 1 |
| Procaccini, E | 1 |
| Signore, A | 1 |
| Xu, S | 1 |
| Gale, EA | 1 |
| Pozzilli, P | 1 |
| Groenewoud, Y | 1 |
| Vranic, M | 2 |
| Giacca, A | 2 |
| Cottrell, DA | 2 |
| Buschard, K | 1 |
| Bock, T | 1 |
| Pedersen, CR | 1 |
| Hansen, SV | 1 |
| Aaen, K | 1 |
| Jørgensen, M | 1 |
| Hansen, MW | 1 |
| Kjaer, TW | 1 |
| Hageman, I | 1 |
| Josefsen, K | 1 |
| AvRuskin, TW | 1 |
| Juan, CS | 1 |
| Adibi, SA | 1 |
| Morse, EL | 1 |
| Amin, PM | 1 |
| Smith, TM | 1 |
| Kilo, C | 1 |
| Williamson, JR | 1 |
| Fajans, SS | 2 |
| Cloutier, MC | 1 |
| Crowther, RL | 1 |
| Shen, SW | 1 |
| Bressler, R | 1 |
| Ellorhaoui, M | 1 |
| Jahnke, KA | 1 |
| Reis, HE | 1 |
| Jahnke, K | 1 |
| Willms, B | 1 |
| Takeda, R | 1 |
| Usukura, N | 1 |
| Miwa, U | 1 |
| Nakabayashi, H | 1 |
| Kishitani, M | 1 |
| Krause, U | 1 |
| Cordes, U | 1 |
| Beyer, J | 1 |
| Sodoyez-Goffaux, F | 1 |
| Sodoyez, JC | 1 |
| Atzenhofer, K | 1 |
| Schnetz, H | 1 |
| Johansen, K | 5 |
| Gottlieb, MS | 1 |
| Park, BN | 1 |
| Kaufmann, RL | 1 |
| Tan, MH | 1 |
| Otto-Buczkowska, E | 1 |
| Kokot, F | 1 |
| Kuska, J | 1 |
| Chiumello, G | 4 |
| Bierman, EL | 1 |
| Henry, ML | 1 |
| Tesi, RJ | 1 |
| Ferguson, RM | 1 |
| O'Dorisio, TM | 1 |
| Oshiro, K | 1 |
| Murakami, K | 1 |
| Sunagawa, R | 1 |
| Mimura, G | 1 |
| Finegood, DT | 1 |
| Hramiak, IM | 1 |
| Dupre, J | 1 |
| Kitagawa, Y | 1 |
| Kanatsuna, T | 1 |
| Kajiyama, S | 1 |
| Nakamura, N | 1 |
| Nakamura, Y | 1 |
| Kano, Y | 1 |
| Nakano, K | 1 |
| Kondo, M | 1 |
| Ludvigsson, J | 1 |
| Segers, O | 1 |
| De Vroede, M | 1 |
| Michotte, Y | 1 |
| Somers, G | 1 |
| Borisova, AM | 3 |
| Koev, D | 2 |
| Kirilov, G | 3 |
| Chiba, T | 1 |
| Okimura, Y | 1 |
| Kodama, H | 1 |
| Kadowaki, S | 1 |
| Chihara, K | 1 |
| Fujita, T | 1 |
| Mokuda, O | 1 |
| Murakami, I | 1 |
| Ikeda, T | 1 |
| Tominaga, M | 1 |
| Mashiba, H | 1 |
| Amemiya, S | 1 |
| Higashida, K | 1 |
| Fujimoto, M | 1 |
| Asayama, K | 1 |
| Ichimura, K | 1 |
| Kusano, S | 1 |
| Ohyama, K | 1 |
| Kato, K | 1 |
| Ovcharova, N | 1 |
| Ser, I | 2 |
| Schemmel, K | 1 |
| Haupt, E | 1 |
| Leybold, K | 1 |
| Lister, J | 1 |
| Lundbaek, K | 1 |
| Lenti, G | 2 |
| Gajdos, A | 1 |
| Pagliara, AS | 1 |
| Karl, IE | 1 |
| Kipnis, DB | 1 |
| Parra, A | 1 |
| Pérez-Pasten, E | 1 |
| Rosales, R | 1 |
| Cervantes, C | 1 |
| Argote, RM | 1 |
| García, G | 1 |
| Adlung, J | 1 |
| Koch, CD | 1 |
| Gottesbüren, H | 1 |
| Schmidt, E | 1 |
| Menge, H | 1 |
| Bloch, R | 1 |
| Lorenz-Meyer, H | 1 |
| Riecken, EO | 1 |
| Del Guercio, MJ | 1 |
| Di Natale, B | 1 |
| Devetta, M | 1 |
| Caccamo, A | 1 |
| Rosenbloom, AL | 3 |
| Bianchi, R | 1 |
| Chin, FT | 1 |
| Guthrie, RA | 2 |
| Guthrie, DW | 1 |
| Baker, HW | 1 |
| Jackson, RL | 2 |
| Cicognani, A | 1 |
| Tassoni, P | 1 |
| Pirazzoli, P | 1 |
| Collina, A | 1 |
| Cacciari, E | 1 |
| Ludwiczak, H | 1 |
| Symonides-Lawecka, A | 1 |
| Rogala, H | 2 |
| Lawecki, J | 2 |
| Fedorowicz, B | 1 |
| Pildes, RS | 2 |
| Drash, A | 3 |
| Ehrlich, RM | 1 |
| Martin, JM | 1 |
| Balsam, MJ | 1 |
| Carroll, KF | 1 |
| Nestel, PJ | 1 |
| Peden, VH | 1 |
| Powell, KR | 1 |
| Rejent, AJ | 1 |
| Grabner, W | 1 |
| Bergner, D | 1 |
| Sommer, B | 1 |
| Ghidoni, A | 1 |
| Lacy, PE | 1 |
| Handwerger, S | 1 |
| Roth, J | 1 |
| Gorden, P | 1 |
| Di Sant' Agnese, P | 1 |
| Carpenter, DF | 1 |
| Peter, G | 1 |
| Jacker, HJ | 1 |
| Kipnis, DM | 3 |
| Hermon-Taylor, J | 1 |
| Parker, ML | 1 |
| Chao, KL | 1 |
| Cornblath, M | 1 |
| Bacon, GE | 1 |
| Parkhurst, RD | 1 |
| Lubetzki, J | 1 |
| Schiff, D | 1 |
| Stern, L | 1 |
| Laor, J | 1 |
| Levitus, Z | 1 |
| Floyd, JC | 1 |
| Pek, S | 1 |
| Conn, JW | 1 |
| Daweke, H | 1 |
| Grote, W | 1 |
| Gries, FA | 1 |
| Liebermeister, H | 1 |
| Rehfeld, JF | 1 |
| Kowalski, H | 1 |
| Kuntz, E | 1 |
| Sperling, M | 1 |
| Schiavini, CA | 1 |
| Quaglia, P | 1 |
| Raptis, S | 1 |
| Rothenbuchner, G | 1 |
| Pfeiffer, EF | 1 |
| Carlström, S | 1 |
| Lundquist, A | 1 |
| Lundquist, I | 1 |
| Nordén, A | 1 |
| Scherstén, B | 1 |
| Wollmark, G | 1 |
| Pagano, G | 2 |
| Mascia, V | 2 |
| Cirillo, R | 2 |
| Pellegrini, A | 2 |
| Falorni, A | 1 |
| Sachsse, B | 1 |
| Yazdanfar, A | 1 |
| Field, JB | 1 |
| Garces, LY | 1 |
| Kenny, FM | 1 |
| Mintz, D | 1 |
| Vazquez, AM | 1 |
| Gellissen, K | 1 |
| Weber, B | 1 |
| Helge, H | 1 |
| Sihombing, G | 1 |
| Orskov, H | 1 |
| Creutzfeldt, W | 1 |
| Frerichs, H | 1 |
| Kosaka, K | 1 |
| Hagura, R | 1 |
| Saito, R | 1 |
| Tsukamoto, F | 1 |
| Kuzuya, T | 1 |
| Murthy, DY | 1 |
| Womack, WN | 1 |
| Muntoni, S | 1 |
| Boero, A | 1 |
| Corona, M | 1 |
| Schneider, H | 1 |
| Colombo, JP | 1 |
| Braunsteiner, H | 1 |
| Hansen, W | 1 |
| Jung, A | 1 |
| Sailer, S | 1 |
8 reviews available for tolbutamide and Autoimmune Diabetes
| Article | Year |
|---|---|
Clinical and etiological heterogeneity of idiopathic diabetes mellitus. The banting memorial lecture.
Topics: Adenoma, Islet Cell; Adult; Antibodies, Viral; Autoantibodies; Cell Adhesion; Chlorpropamide; Chromo | 1979 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
[Early diagnosis and prevention of Diabetes mellitus].
Topics: Austria; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; England; Female; Germany, East | 1975 |
Pathobiology of the islets of Langerhans.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose; Insulin; Insulin Secretion; Islets of Langerh | 1969 |
[Antidiabetics. 42].
Topics: Adolescent; Adult; Aged; Biguanides; Carbutamide; Child; Child, Preschool; Diabetes Mellitus; Diabet | 1969 |
Insulin secretion in normal and diabetic individuals.
Topics: Adolescent; Amino Acids; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose; | 1970 |
[A review of pancreatic transplantation in man, and function of the pancreaticoduodenal graft].
Topics: Adult; Diabetes Mellitus, Type 1; Duodenum; Humans; Insulin; Pancreas; Pancreas Transplantation; Pan | 1970 |
Metabolic considerations in the treatment of juvenile diabetes mellitus.
Topics: Acid-Base Equilibrium; Amino Acids; Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Diab | 1969 |
9 trials available for tolbutamide and Autoimmune Diabetes
| Article | Year |
|---|---|
Direct comparison of standard and insulin modified protocols for minimal model estimation of insulin sensitivity in normal subjects.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Insulin; In | 1994 |
Insulin secretion, insulin action and non-insulin-dependent glucose uptake in pancreas transplant recipients.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Glucose | 1994 |
Role of insulin and glucose in the induction of hypoaminoacidemia in man: studies in normal, juvenile diabetic, and insuloma patients.
Topics: Adenoma, Islet Cell; Administration, Oral; Adolescent; Adult; Amino Acids; Blood Glucose; Clinical T | 1975 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
Chemical diabetes mellitus in siblings of children with overt diabetes.
Topics: Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Hyperins | 1972 |
Tolbutamide in chemical diabetes mellitus in children.
Topics: Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; | 1973 |
Criteria for the selection of patients for treatment with tolbutamide.
Topics: Child; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diet Therapy; Evaluation Studies as Topi | 1973 |
Oral substitutes for insulin: modern appraisal of their action and indications.
Topics: Adolescent; Adult; Aged; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet, | 1972 |
Studies in subjects with positive postprandial Clinistix test. 3. Special studies and follow-up of cases with borderline glucose tolerance.
Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Fas | 1971 |
115 other studies available for tolbutamide and Autoimmune Diabetes
| Article | Year |
|---|---|
Favorable effects of supplemental orinase in insulin-treated labile diabetes.
Topics: Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Tolbutamide | 1957 |
Use of orinase as a basic adjuvant in management of insulin-dependent diabetes.
Topics: Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Insulin; Tolbutamide | 1958 |
[Clinical study of tolbutamide therapy of juvenile diabetes].
Topics: Diabetes Mellitus, Type 1; Humans; Hypoglycemic Agents; Tolbutamide | 1958 |
Combined insulin-tolbutamide therapy in the management of insulin-dependent diabetes.
Topics: Diabetes Mellitus, Type 1; Disease Management; Insulin; Tolbutamide | 1959 |
The intravenous tolbut-amide response test in infants and children. A preliminary report.
Topics: Adolescent; Amides; Child; Diabetes Mellitus, Type 1; Humans; Infant; Tolbutamide | 1962 |
[EFFECT OF TOLBUTAMIDE IN DIABETES IN CHILDREN AND ADOLESCENTS].
Topics: Adolescent; Blood Glucose; Child; Diabetes Mellitus, Type 1; Humans; Tolbutamide | 1963 |
[SECONDARY HEPATIC GLYCOGENOSIS].
Topics: Adolescent; Adrenocortical Hyperfunction; Carbohydrate Metabolism; Cataract; Child; Diabetes Mellitu | 1963 |
[DIABETES MELLITUS IN THE WILLI-PRADER SYNDROME].
Topics: Adolescent; Child; Congenital Abnormalities; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dwarfism; | 1963 |
[EXPLORATION OF CARBOHYDRATE METABOLISM IN CHILDREN BY INTRAVENOUS ADMINISTRATION OF TOLBUTAMIDE].
Topics: Administration, Intravenous; Adolescent; Blood Glucose; Carbohydrate Metabolism; Child; Diabetes Mel | 1963 |
THE BLOOD CONCENTRATION OF THIAMINE IN DIABETES.
Topics: Blood; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Drug Therapy; Fasting; Geriatric | 1964 |
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN.
Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabete | 1964 |
THE FAMILY DOCTOR AND THE DIABETIC.
Topics: Acidosis; Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic | 1965 |
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Dru | 1965 |
LIMITATIONS IN THE USE OF ORAL HYPOGLYCEMIC AGENTS IN JUVENILE PATIENTS WITH DIABETES.
Topics: Adolescent; Blood Chemical Analysis; Blood Glucose; Body Weight; Child; Cholesterol; Diabetes Mellit | 1965 |
ATP and sulfonylurea sensitivity of mutant ATP-sensitive K+ channels in neonatal diabetes: implications for pharmacogenomic therapy.
Topics: Adenosine Triphosphate; Animals; Cell Line; Diabetes Mellitus, Type 1; Glyburide; Humans; Hypoglycem | 2005 |
An ATP-binding mutation (G334D) in KCNJ11 is associated with a sulfonylurea-insensitive form of developmental delay, epilepsy, and neonatal diabetes.
Topics: Adenosine Triphosphate; Adolescent; Alleles; ATP-Binding Cassette Transporters; Binding Sites; Devel | 2007 |
A novel ABCC8 (SUR1)-dependent mechanism of metabolism-excitation uncoupling.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cell Polarity; Chlorocebus aethi | 2008 |
[Hypoglycemic coma due to oranyl].
Topics: Adolescent; Diabetes Mellitus, Type 1; Diabetic Coma; Humans; Male; Tolbutamide | 1966 |
Effect of intravenous tolbutamide in juvenile diabetes mellitus.
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids; Fatty Acids, Nonesterif | 1967 |
The early partial remission of juvenile diabetes mellitus. The roles of insulin and growth hormone.
Topics: Blood Glucose; Body Height; Body Weight; Calorimetry; Child; Diabetes Mellitus, Type 1; Fatty Acids, | 1967 |
Tolbutamide does not alter insulin requirement in Type 1 (insulin-dependent) diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Fatty Acids, Nonesterified; Glucagon; G | 1984 |
Functional study of insulin secretion pattern following segmental neoprene-injected pancreatic allograft in insulin-dependent (type 1) diabetic recipients.
Topics: Adult; Arginine; Cyclosporins; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; I | 1983 |
Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 1983 |
The effect of glucose, tolbutamide, and arginine on C-peptide release during remission in type I diabetes mellitus.
Topics: Adolescent; Arginine; C-Peptide; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose | 1983 |
Differential sensitivity to beta-cell secretagogues in "early," type I diabetes mellitus.
Topics: Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Insulin Secr | 1984 |
Insulin response to sulphonylureas in diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; Tolbutamide | 1984 |
Sulfonylureas enhance in vivo the effectiveness of insulin in type 1 (insulin dependent) diabetes mellitus.
Topics: Adolescent; Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Female; Glipizide; | 1984 |
C-Peptide reserve in insulin-dependent diabetes. Comparative responses to glucose, glucagon and tolbutamide.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glu | 1980 |
[The significance of insulin secretion in the pathogenesis of diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucagon; Humans; Insulin; Insulin Secretion; Islets o | 1981 |
Permanent neonatal diabetes in an infant of an insulin-dependent mother.
Topics: C-Peptide; Diabetes Mellitus, Type 1; Humans; Infant, Newborn; Insulin; Male; Receptor, Insulin; Tol | 1982 |
Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients.
Topics: Adolescent; Adult; Blushing; C-Peptide; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, | 1980 |
Parotid function and composition of parotid saliva among elderly edentulous African-American diabetics.
Topics: Aged; Analysis of Variance; Baltimore; Black People; Case-Control Studies; Diabetes Mellitus; Diabet | 1994 |
VLDL production is decreased to a similar extent by acute portal vs. peripheral venous insulin.
Topics: Adult; Apolipoproteins B; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Humans; Hyperinsuli | 1994 |
A new method for comparing portal and peripheral venous insulin delivery in humans: tolbutamide versus insulin infusion.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Clamp Technique; Humans; | 1994 |
Differential effects of systemic insulin delivery and prednisone on tissue glucose and insulin sensitivity in insulin-dependent diabetes mellitus pancreas recipients.
Topics: Adult; Azathioprine; Blood Glucose; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; | 1994 |
Tolbutamide reduces the incidence of diabetes mellitus, but not insulitis, in the non-obese-diabetic mouse.
Topics: Aging; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Diazoxide; Female; Insulin; Islets of Lang | 1993 |
Defects in quantitative and qualitative beta-cell function following successful segmental pancreas transplantation. Danish-Swedish Study Group of Metabolic Effect of Pancreas Transplantation (DSSGMEPT).
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Eating; Fasting; | 1993 |
Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans.
Topics: Adult; Algorithms; Analysis of Variance; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Glucon | 1996 |
Normalization of insulin sensitivity and glucose homeostasis in type I diabetic pancreas transplant recipients: a 48-month cross-sectional study--a clinical research center study.
Topics: Adult; Blood Glucose; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Female; Food; G | 1996 |
Glucagon enhances the direct suppressive effect of insulin on hepatic glucose production in humans.
Topics: Adult; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Drug Synergism; Glucagon; Glucose; Human | 1997 |
Neonatal treatment with beta-cell stimulatory agents reduces the incidence of diabetes in BB rats.
Topics: Animals; Animals, Newborn; Arginine; Diabetes Mellitus, Type 1; Drug Combinations; Female; Glucagon; | 2000 |
Transient neonatal diabetes mellitus, type 4, type 1 diabetes mellitus, or MODY: which disease is it, anyway?
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 2002 |
Monozygotic triplets with discordance for diabetes mellitus and diabetic microangiopathy.
Topics: Adolescent; Adult; Antigens; Basement Membrane; Blood Glucose; Capillaries; Cortisone; Diabetes Mell | 1977 |
[Various disturbances in beta cell function in diabetes mellitus].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose; Humans; Insulin; Islets of | 1977 |
[Assessment of the B-cell function in diabetic patients by means of the determination of insulin secretion following glucose-tolbutamide stimulation].
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Insulin | 1976 |
[The importance of serum insulin determination in the diagnosis and treatment of diabetes mellitus (author's transl)].
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Dose-Response Relationshi | 1975 |
Plasma immunoreactive insulin response to 100g-glucose-glucagon-tolbutamide stimulation in juvenile-onset diabetics.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin | 1977 |
[C-peptide: secretion and metabolism in different functional states and with abnormal B-cell function (author's transl)].
Topics: C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose; Half-Life; Humans; Insulin; Pancre | 1977 |
Transient diabetes mellitus in a neonate. Evaluation of insulin, glucagon, and growth hormone secretion and management with a continuous low-dose insulin infusion.
Topics: Adolescent; Antigens; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance | 1977 |
Serum insulin and growth hormone response patterns in monozygotic twin siblings of patients with juvenile-onset diabetes.
Topics: Adolescent; Adult; Antigens; Blood Glucose; Child; Diabetes Mellitus, Type 1; Diseases in Twins; Fat | 1975 |
[Benign diabetes in children (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diagnosis, Differential; Female; Hum | 1975 |
[Infantile diabetes].
Topics: Adolescent; Arginine; Child; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Test; Hu | 1976 |
The oral antidiabetic agents.
Topics: Administration, Oral; Adult; Blood Glucose; Body Weight; Cardiovascular Diseases; Diabetes Mellitus; | 1976 |
Minimal model analysis of insulin sensitivity and glucose-mediated glucose disposal in type 1 (insulin-dependent) diabetic pancreas allograft recipients.
Topics: Adult; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 1; Female; Humans; Insul | 1992 |
Chronic effects of tolbutamide on myocardial tension during ischemia and reperfusion in perfused hearts isolated from insulin dependent and non insulin dependent diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1991 |
A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes.
Topics: Adolescent; Adult; Blood Glucose; Child; Computer Simulation; Diabetes Mellitus, Type 1; Dose-Respon | 1990 |
Islet cell surface antibodies preferentially inhibit glucose-stimulated insulin release in vitro.
Topics: Adolescent; Adult; Animals; Arginine; Autoantibodies; Child; Diabetes Mellitus; Diabetes Mellitus, T | 1990 |
Basal and tolbutamide-induced plasma somatostatin in healthy subjects and in patients with diabetes and impaired glucose tolerance.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucose To | 1989 |
[An improvement in insulin efficacy in patients with type-1 diabetes mellitus following treatment using an insulin infusion pump].
Topics: Blood Glucose; C-Peptide; Chronic Disease; Diabetes Mellitus, Type 1; Drug Evaluation; Humans; Insul | 1989 |
[Factors affecting stability in the course of insulin-dependent diabetes mellitus].
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Chronic Disease; Circadian Rhythm; Diabetes Mellitus, T | 1989 |
Tolbutamide inhibits gastrin release in man.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Drug Administration Routes; Female; Gastric Acid; G | 1988 |
Plasma glucose response after intravenous injection of tolbutamide in insulin-treated type I and type II diabetic patients.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; | 1988 |
Residual pancreatic beta-cell function in insulin-dependent diabetes mellitus.
Topics: Adolescent; Arginine; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucagon; Glucose Toleranc | 1987 |
[Insulin secretion and action in acromegaly].
Topics: Acromegaly; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Gro | 1987 |
Plasma-insulin in a young diabetic after 13 years' oral therapy.
Topics: Administration, Oral; Adolescent; Child; Chlorpropamide; Diabetes Mellitus, Type 1; Humans; Insulin; | 1971 |
[In-vitro changes of the serum binding capacity for 131 I-insulin under tolbutamide and glybenclamide in normal persons, in juvenile and senile diabetes, as well as in insulin resistance].
Topics: Age Factors; Blood Glucose; Chromatography, Gel; Cyclohexanes; Diabetes Mellitus; Diabetes Mellitus, | 1970 |
The clinical spectrum of juvenile diabetes.
Topics: Child; Child, Preschool; Classification; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; | 1966 |
Plasma-insulin in mild juvenile diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Immunoassay; Insulin; Insu | 1967 |
[The diabetic disease (M.D.). Clinical picture and complications].
Topics: Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabeti | 1974 |
[Some new data on the biochemistry of insulin].
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Amino Acid Sequence; Amino Acids; Animals; Chemical Phe | 1969 |
Transient neonatal diabetes: delayed maturation of the pancreatic beta cell.
Topics: Adenylyl Cyclases; Blood Glucose; Caffeine; Cyclic AMP; Diabetes Mellitus, Type 1; Female; Glucose T | 1973 |
[Hyperinsulinemia in children with chemical diabetes mellitus].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose Toler | 1974 |
Influence of tolbutamide on serum glucose level, specific activity of glucose and glucose oxidation in severe diabetes.
Topics: Adolescent; Adult; Aged; Blood Glucose; Carbon Dioxide; Carbon Radioisotopes; Diabetes Mellitus; Dia | 1974 |
The effect of diabetes mellitus and insulin on the absorption of glucose, water and electrolytes by the small intestine in man.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose; Humans; Insulin; Intestinal Absorption; Jejun | 1973 |
B-pancreatic function in obese and diabetic children.
Topics: Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Ethylenediamines; Female; Glucagon; Gluco | 1972 |
[Infantile diabetes and treatment with oral hypoglycemizing agents (function tests of the endocrine pancreatic before and after one year of therapy)].
Topics: Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Glyburide; Human | 1972 |
[Spontaneous remissions in the early stage of diabetes in children].
Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Humans; Male; Remissio | 1972 |
Adult-onset diabetes mellitus in childhood.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fa | 1973 |
Treatment of the child with chemical diabetes mellitus.
Topics: Child; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucose Tolerance Test; Humans; Hypoglycemia; I | 1973 |
Early diabetes mellitus in children.
Topics: Body Weight; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diet Therapy; Female; Follow-Up Stu | 1973 |
Chemical diabetes in children: tolbutamide experience.
Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Follow-Up Studies; Glucose Tolerance | 1973 |
Diurnal variation in glucose tolerance and in insulin secretion in man.
Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 1; | 1973 |
Glucose intolerance in a three-year-old child with cystic fibrosis.
Topics: Anti-Bacterial Agents; Blood Glucose; Child, Preschool; Cystic Fibrosis; Diabetes Mellitus, Type 1; | 1974 |
[Accuracy of radioimmunologic insulin determination].
Topics: Diabetes Mellitus, Type 1; Glucagon; Glucose; Humans; Insulin; Iodine Isotopes; Isotope Labeling; Pa | 1974 |
[Behavior of insulin-like activity in juvenile diabetics].
Topics: Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Humans; Insulin; Islets | 1966 |
Glucose intolerance in cystic fibrosis.
Topics: Adolescent; Adult; Blood Glucose; Child; Cystic Fibrosis; Diabetes Mellitus; Diabetes Mellitus, Type | 1969 |
Juvenile diabetes mellitus, a deficiency in insulin.
Topics: Arginine; Child; Diabetes Mellitus, Type 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Insuli | 1968 |
[Considerations on diabetic angiopathies. Relations to hypoglycemic treatments].
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dia | 1972 |
Metabolic and growth patterns in transient neonatal diabetes.
Topics: Birth Weight; Blood Glucose; Body Height; Body Weight; Diabetes Mellitus, Type 1; Glucose; Glucose T | 1972 |
[The diagnostic value of insulin measurement in juvenile diabetes and in diabetics on peroral therapy].
Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Humans | 1971 |
The course of asymptomatic diabetes in young people, as determined by levels of blood glucose and plasma insulin.
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; | 1969 |
[Genetics of diabetes mellitus: glucose tolerance, serum insulin and free fatty acids in monozygotic twins].
Topics: Adult; Blood Glucose; Blood Group Antigens; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Dis | 1970 |
Insulin responses of children with chemical diabetes mellitus.
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fe | 1970 |
A case of asymptomatic juvenile diabetes mellitus with severe insulin deficiency.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Glycosuria; Hum | 1970 |
Studies on the radioimmunological determination of blood insulin by means of 125-I-insulin of high specific activity.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Animals; Blood Glucose; Diabetes Mellitus, Type 1; | 1970 |
[Classification and clinical picture of diabetes mellitus].
Topics: Age Factors; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Neuropat | 1970 |
Evolution of diabetes mellitus from hypoglycemia.
Topics: Adolescent; Blood Glucose; Child; Chronic Disease; Diabetes Mellitus, Type 1; Drug Tolerance; Female | 1971 |
[On a case of diabetes mellitus with unusual evolution].
Topics: Adolescent; Arginine; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Tes | 1971 |
[Progress in the therapy of diabetes].
Topics: Adrenal Cortex Hormones; Adult; Aged; Aminocaproates; Animals; Biguanides; Blood Glucose; Child; Dia | 1971 |
Mild carbohydrate intolerance developing into classic juvenile diabetes.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Diabetes Mellitus, Type 1; Glucose Tol | 1971 |
[The dynamics of free and conugated insulin of the blood in infantile prediabetes and diabetes. Physiopathological considerations].
Topics: Adolescent; Adult; Child; Child, Preschool; Diabetes Mellitus, Type 1; Glucose Tolerance Test; Human | 1967 |
[Criteria for the diagnosis of early diabetes].
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Child, Preschool; Cortisone; Diabetes Mellitus; Diabe | 1968 |
[The dynamics of insulinemia in man after administration of tolbutamide].
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Insulin; Mid | 1968 |
Endogenous insulin and growth hormone response in children with newly diagnosed diabetes mellitus.
Topics: Adolescent; Arginine; Carbon Dioxide; Child; Child, Preschool; Chlorides; Diabetes Mellitus, Type 1; | 1968 |
[The intravenous tolbutamide test in childhood].
Topics: Adolescent; Age Factors; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; | 1968 |
[Mild diabetes mellitus in children and young adults. Clinical features and endogenous insulin response].
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Glucose Toleran | 1968 |
Insulin secretion in diabetes mellitus.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; | 1968 |
[Plasma concentrations of insulin and free fatty acids in juvenile diabetes after loading with tolbutamide and glucagon].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Fatty Acids; Glucagon | 1968 |
Plasma insulin during remission in juvenile diabetes mellitus.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Female; Glucose Tolerance | 1969 |
[Hypoglycemia factitia. A differential diagnostic significant form of hyperinsulinism].
Topics: Adolescent; Diabetes Mellitus, Type 1; Diabetic Coma; Diagnosis, Differential; Female; Humans; Hyper | 1969 |
Changes in plasma insulin and glucose tolerance in stable diabetes in a young woman.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glucagon; Glucose Tolerance Tes | 1969 |
Chemical and early overt diabetes mellitus in children. II. Effect of intravenous tolbutamide on "insulin reserve".
Topics: Adolescent; Adult; Blood Glucose; Child; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; | 1969 |
[Significance and importance of fibrinolytic activation due to tolbutamide].
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Fibrinolysis; Humans; Tolbutamide | 1965 |
[Tolbutamide tests in children].
Topics: Adenoma; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diagnosis, Differential; | 1965 |
[Latent diabetic metabolic state in parents of juvenile diabetics].
Topics: Adolescent; Adult; Blood Glucose; Carbohydrate Metabolism; Child; Child, Preschool; Diabetes Mellitu | 1966 |