Page last updated: 2024-11-05

tolbutamide and Ataxia Telangiectasia

tolbutamide has been researched along with Ataxia Telangiectasia in 1 studies

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schalch, DS1
McFarlin, DE1
Barlow, MH1

Other Studies

1 other study available for tolbutamide and Ataxia Telangiectasia

ArticleYear
An unusual form of diabetes mellitus in ataxia telangiectasia.
    The New England journal of medicine, 1970, Jun-18, Volume: 282, Issue:25

    Topics: Adolescent; Adult; Ataxia Telangiectasia; Blood Glucose; Child; Diabetes Mellitus; Fatty Acids, None

1970