tolbutamide has been researched along with Arrhythmias, Cardiac in 9 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim was to study the effects of nicorandil (an ATP-sensitive K+ channel opener) and tolbutamide (an ATP-sensitive K+ channel blocker) on reperfusion-induced arrhythmias in pentobarbitone and ketamine anesthetized rabbits." | 7.71 | Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 7.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| "The aim was to study the effects of nicorandil (an ATP-sensitive K+ channel opener) and tolbutamide (an ATP-sensitive K+ channel blocker) on reperfusion-induced arrhythmias in pentobarbitone and ketamine anesthetized rabbits." | 3.71 | Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits. ( Das, B; Karanth, KS; Sarkar, C, 2001) |
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 3.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakaya, H | 1 |
| Das, B | 1 |
| Sarkar, C | 1 |
| Karanth, KS | 1 |
| Zhang, HL | 1 |
| Li, YS | 1 |
| Fu, SX | 1 |
| Yang, XP | 1 |
| Ballagi-Pordány, G | 1 |
| Köszeghy, A | 1 |
| Koltai, MZ | 1 |
| Aranyi, Z | 1 |
| Pogátsa, G | 1 |
| Wolleben, CD | 1 |
| Sanguinetti, MC | 1 |
| Siegl, PK | 1 |
| Bressler, R | 1 |
| Cordon, MV | 1 |
| Clayman, CB | 1 |
| Opie, LH | 1 |
| Keen, H | 1 |
| Jarrett, RJ | 1 |
| Ward, JD | 1 |
| Fuller, JH | 1 |
2 reviews available for tolbutamide and Arrhythmias, Cardiac
| Article | Year |
|---|---|
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias].
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; G | 1993 |
The general and local metabolic response to acute myocardial infarction.
Topics: Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Arrhythmias, Cardiac; Blood Glucose; Catecholamine | 1972 |
1 trial available for tolbutamide and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Borderline diabetics and their response to tolbutamide.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Diab | 1973 |
6 other studies available for tolbutamide and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; | 2001 |
Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig.
Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; Hyp | 1991 |
Divergent cardiac effects of the first and second generation hypoglycemic sulfonylurea compounds.
Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Carbutamide; Dose-Response Relationship, Drug; Electro | 1990 |
Influence of ATP-sensitive potassium channel modulators on ischemia-induced fibrillation in isolated rat hearts.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Coronar | 1989 |
The effect of beta-adrenergic receptor blocking agents on drug-induced insulin secretion.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenocorticotropic Hormon | 1970 |
Letter: Tolbutamide revisited.
Topics: Animals; Arrhythmias, Cardiac; Cardiovascular Diseases; Heart; Humans; Hypoglycemic Agents; Phenform | 1974 |