tolbutamide has been researched along with Amyotrophic Lateral Sclerosis in 6 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STEINKE, J | 1 |
| TYLER, HR | 1 |
| Quick, DT | 2 |
| Greer, M | 1 |
| Collis, WJ | 1 |
| Engel, WK | 1 |
| Mueller, PS | 1 |
| Utterback, RA | 1 |
| Cummins, AJ | 1 |
| Cape, CA | 1 |
| Goldenberg, J | 1 |
| Brown, JC | 1 |
| Kater, RM | 1 |
6 other studies available for tolbutamide and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
THE ASSOCIATION OF AMYOTROPHIC LATERAL SCLEROSIS (MOTOR NEURON DISEASE) AND CARBOHYDRATE INTOLERANCE, A CLINICAL STUDY.
Topics: Amyotrophic Lateral Sclerosis; Blood Glucose; Carbohydrate Metabolism; Carbohydrate Metabolism, Inbo | 1964 |
Pancreatic dysfunction in patients with amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Female; Glucose Tolerance Test; Humans; Injections, Intravenous | 1967 |
Glucose metabolism in five neuromuscular disorders.
Topics: Amyotrophic Lateral Sclerosis; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Insulin; | 1968 |
Studies of glucose, insulin, and lipid metabolism in amyotrophic lateral sclerosis and other neuromuscular disorders.
Topics: Adult; Amyotrophic Lateral Sclerosis; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Female | 1970 |
Pancreatic function in amyotrophic lateral sclerosis.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Deficiency Diseases; Drug Tolerance; Electromyography; F | 1970 |
Pancreatic function in patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amylases; Amyotrophic Lateral Sclerosis; Bicarbonates; Female; Gastric Juice; Glucose T | 1969 |