tolbutamide has been researched along with Alloxan Diabetes in 139 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Stevioside, a glycoside contained in the leaves of Stevia rebaudiana Bertoni (Compositae), was used to screen the effect induced by a diet containing 60% fructose on insulin resistance in rats." | 7.73 | Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats. ( Chang, JC; Cheng, JT; Liu, IM; Wu, MC, 2005) |
| " Stevioside, a glycoside contained in the leaves of Stevia rebaudiana Bertoni (Compositae), was used to screen the effect induced by a diet containing 60% fructose on insulin resistance in rats." | 3.73 | Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats. ( Chang, JC; Cheng, JT; Liu, IM; Wu, MC, 2005) |
| " Treatment of fed mice with MH before alloxan caused a marked "initial" hyperglycaemia but no second hyperglycaemia, and thus no development of alloxan diabetes." | 3.66 | Effects of D-mannoheptulose on blood glucose and alloxan sensitivity in mice. ( Boquist, L, 1980) |
| " When membrane potential was plotted as a function of glucose concentration, the dose-response curve was shifted to the left." | 1.29 | Diminished fraction of blockable ATP-sensitive K+ channels in islets transplanted into diabetic mice. ( Andreu, E; Martín, F; Montana, E; Nacher, V; Sanchez-Andrés, JV; Soria, B, 1996) |
| " Further evidence for a lack of a diabetogenic role for GH comes from the inability of chronic administration of GH to influence the decline in plasma concentrations of glucose following challenge with the insulin secretagogue, tolabutamide." | 1.28 | Lipolytic and diabetogenic effects of native and biosynthetic growth hormone in the chicken: a re-evaluation. ( Scanes, CG, 1992) |
| "Basal values of T increased in both T-IDDM and T-NIDDM, compared to IDDM and NIDDM, respectively." | 1.28 | Chronic effects of tolbutamide on myocardial tension during ischemia and reperfusion in perfused hearts isolated from insulin dependent and non insulin dependent diabetic rats. ( Mimura, G; Murakami, K; Oshiro, K; Sunagawa, R, 1991) |
| "With overt IDDM, insulin levels are low and unresponsive." | 1.27 | Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat. ( Marliss, EB; Nakhooda, AF; Poussier, P, 1983) |
| "The dextran-induced anaphylactoid reaction in the rat is susceptible to changes in carbohydrate metabolism." | 1.26 | Effect of oral antidiabetics on the anaphylactoid reaction. ( Koltai, M; Wellinger, K, 1981) |
| "Sixty-seven mongolian gerbils (Meriones unguiculatus), which seem to resemble the sand rats in the manifestation of diabetic syndrome, were used for observations on the development of diabetic process and on the effect of the long term administration of tolbutamide on it." | 1.26 | Studies on diabetic syndrome and influences of long-term tolbutamide administration in Mongolian gerbils (Meriones unguiculatus). ( Nakama, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 85 (61.15) | 18.7374 |
| 1990's | 22 (15.83) | 18.2507 |
| 2000's | 22 (15.83) | 29.6817 |
| 2010's | 8 (5.76) | 24.3611 |
| 2020's | 2 (1.44) | 2.80 |
| Authors | Studies |
|---|---|
| Schweizer, EH | 1 |
| Märki, F | 1 |
| Lehmann, C | 1 |
| Dietrich, H | 1 |
| de Sousa, E | 2 |
| Zanatta, L | 2 |
| Seifriz, I | 1 |
| Creczynski-Pasa, TB | 1 |
| Pizzolatti, MG | 2 |
| Szpoganicz, B | 2 |
| Silva, FR | 2 |
| Wang, Z | 2 |
| Li, QQ | 2 |
| Huang, CK | 2 |
| Dong, YY | 2 |
| Lang, LP | 2 |
| Sun, W | 2 |
| Qian, JC | 2 |
| Zhang, XD | 2 |
| Dutta, SM | 1 |
| Chen, G | 1 |
| Maiti, S | 1 |
| Shi, Y | 1 |
| Xue, J | 1 |
| Jia, L | 1 |
| Du, Q | 1 |
| Niu, J | 1 |
| Zhang, D | 1 |
| Ma, Z | 1 |
| Moruzzi, N | 1 |
| Catrina, SB | 1 |
| Hals, I | 1 |
| Oberholzer, J | 1 |
| Grill, V | 1 |
| Björklund, A | 1 |
| Zahid, H | 1 |
| Rizwani, GH | 1 |
| Shareef, H | 1 |
| Khursheed, R | 1 |
| Huma, A | 1 |
| Hasan, SM | 1 |
| Liu, R | 1 |
| Wang, H | 1 |
| Xu, B | 1 |
| Chen, W | 1 |
| Turlova, E | 1 |
| Dong, N | 1 |
| Sun, CL | 1 |
| Lu, Y | 1 |
| Fu, H | 1 |
| Shi, R | 1 |
| Barszczyk, A | 1 |
| Yang, D | 1 |
| Jin, T | 1 |
| Mannucci, E | 1 |
| Feng, ZP | 1 |
| Sun, HS | 1 |
| Bhaskar, A | 1 |
| Vidhya, VG | 1 |
| Ramya, M | 1 |
| Aguilar-Santamaría, L | 1 |
| Ramírez, G | 1 |
| Nicasio, P | 1 |
| Alegría-Reyes, C | 1 |
| Herrera-Arellano, A | 1 |
| Kumar, G | 2 |
| Banu, S | 1 |
| Murugesan, AG | 2 |
| Gier, B | 1 |
| Krippeit-Drews, P | 1 |
| Sheiko, T | 1 |
| Aguilar-Bryan, L | 1 |
| Bryan, J | 1 |
| Düfer, M | 1 |
| Drews, G | 1 |
| Gayathri, M | 1 |
| Kannabiran, K | 1 |
| Rai, PK | 1 |
| Mehta, S | 1 |
| Watal, G | 2 |
| Fagbohun, TR | 1 |
| Odufuwa, KT | 1 |
| Ahmadi, A | 1 |
| Khalili, M | 1 |
| Seyedhoseyni, S | 1 |
| Roudsari, EM | 1 |
| Nahri-Niknafs, B | 1 |
| MIRSKY, IA | 2 |
| GITELSON, S | 2 |
| PERISUTTI, G | 1 |
| GRYGLEWSKI, R | 1 |
| DUNCAN, LJ | 1 |
| DULIN, WE | 1 |
| ADAMKIEWICZ, VW | 1 |
| FITKO, RJ | 1 |
| FORTIER, AA | 1 |
| DEROETTH, A | 1 |
| PEI, YF | 1 |
| YAMAGATA, S | 1 |
| OHNEDA, A | 1 |
| FOA, PP | 1 |
| CHATTERJEE, KP | 1 |
| TANAYAMA, S | 1 |
| UI, M | 1 |
| LAZAROW, A | 1 |
| TREIBERGS, B | 1 |
| Kesari, AN | 1 |
| Gupta, RK | 1 |
| Orhan, DD | 1 |
| Aslan, M | 1 |
| Sendogdu, N | 1 |
| Ergun, F | 1 |
| Yesilada, E | 1 |
| Kasiviswanath, R | 1 |
| Ramesh, A | 1 |
| Kumar, KE | 1 |
| Liu, TP | 1 |
| Lee, CS | 1 |
| Liou, SS | 1 |
| Liu, IM | 5 |
| Cheng, JT | 5 |
| Kothai, R | 1 |
| Arul, B | 1 |
| Kumar, KS | 1 |
| Christina, AJ | 1 |
| Chang, JC | 1 |
| Wu, MC | 1 |
| Sharma, SB | 1 |
| Nasir, A | 1 |
| Prabhu, KM | 2 |
| Murthy, PS | 3 |
| Momo, CE | 1 |
| Oben, JE | 1 |
| Tazoo, D | 1 |
| Dongo, E | 1 |
| Rajasekara Pandian, M | 1 |
| Cazarolli, LH | 1 |
| Junior, AC | 1 |
| Chen, CC | 1 |
| Murugesh, K | 1 |
| Yeligar, V | 1 |
| Dash, DK | 1 |
| Sengupta, P | 1 |
| Maiti, BC | 1 |
| Maity, TK | 1 |
| Datar, SP | 1 |
| Suryavanshi, DS | 1 |
| Bhonde, RR | 1 |
| Hsu, JH | 1 |
| Wu, YC | 1 |
| Murali, YK | 1 |
| Anand, P | 1 |
| Tandon, V | 1 |
| Singh, R | 1 |
| Chandra, R | 1 |
| McDonald, HJ | 1 |
| DeChatelet, LR | 1 |
| Weir, GC | 1 |
| Clore, ET | 1 |
| Zmachinski, CJ | 1 |
| Bonner-Weir, S | 1 |
| Kobayashi, T | 1 |
| Sawano, S | 1 |
| Itoh, T | 1 |
| Takeda, S | 1 |
| Kokubu, T | 1 |
| Chiba, T | 2 |
| Taminato, T | 2 |
| Kadowaki, S | 2 |
| Chihara, K | 1 |
| Matsukura, S | 1 |
| Seino, Y | 1 |
| Fujita, T | 2 |
| Nozawa, M | 1 |
| Norman, AW | 1 |
| Wellinger, K | 1 |
| Koltai, M | 1 |
| Giroix, MH | 1 |
| Portha, B | 1 |
| Kergoat, M | 1 |
| Bailbe, D | 1 |
| Picon, L | 1 |
| Marliss, EB | 1 |
| Nakhooda, AF | 1 |
| Poussier, P | 1 |
| Valentovic, MA | 1 |
| Lubawy, WC | 1 |
| Tutwiler, GF | 3 |
| Fawthrop, H | 1 |
| Vanderweele, DA | 1 |
| Suzuki, J | 1 |
| Kimura, M | 1 |
| Tan, BH | 1 |
| Wilson, GL | 1 |
| Schaffer, SW | 1 |
| Annamala, PT | 1 |
| Augusti, KT | 4 |
| Boquist, L | 2 |
| Kaul, CL | 1 |
| Talwalker, PK | 1 |
| Grewal, RS | 1 |
| Anton, AH | 1 |
| Berk, AI | 1 |
| Torella, R | 1 |
| Improta, L | 1 |
| Scognamiglio, G | 1 |
| Siniscalchi, N | 1 |
| Jori, GP | 1 |
| Anturlikar, SD | 1 |
| Gopumadhavan, S | 1 |
| Chauhan, BL | 1 |
| Mitra, SK | 1 |
| Chattopadhyay, RR | 1 |
| Kato, A | 1 |
| Miura, T | 1 |
| Katsumata, K | 6 |
| Katsumata, Y | 5 |
| Ozawa, T | 1 |
| Hotta, N | 1 |
| Komori, T | 1 |
| Kobayashi, M | 1 |
| Sakakibara, F | 1 |
| Koh, N | 1 |
| Sakamoto, N | 1 |
| Soria, B | 1 |
| Martín, F | 1 |
| Andreu, E | 1 |
| Sanchez-Andrés, JV | 1 |
| Nacher, V | 1 |
| Montana, E | 1 |
| Mukherjee, PK | 1 |
| Saha, K | 1 |
| Pal, M | 1 |
| Saha, BP | 1 |
| Luo, J | 1 |
| Quan, J | 1 |
| Tsai, J | 1 |
| Hobensack, CK | 1 |
| Sullivan, C | 1 |
| Hector, R | 1 |
| Reaven, GM | 1 |
| Alarcon-Aguilara, FJ | 1 |
| Roman-Ramos, R | 1 |
| Perez-Gutierrez, S | 1 |
| Aguilar-Contreras, A | 1 |
| Contreras-Weber, CC | 1 |
| Flores-Saenz, JL | 1 |
| Leahy, JL | 1 |
| Fineman, MS | 1 |
| Chang, SL | 1 |
| Lin, JG | 1 |
| Chi, TC | 1 |
| Ohta, T | 1 |
| Furukawa, N | 1 |
| Yonemori, F | 1 |
| Wakitani, K | 1 |
| Jafri, MA | 1 |
| Aslam, M | 1 |
| Javed, K | 1 |
| Singh, S | 1 |
| Perez Gutierrez, RM | 1 |
| Ramirez, E | 1 |
| Vargas, R | 1 |
| Kirsch, T | 2 |
| Bridi, G | 1 |
| Palma, JA | 1 |
| Paglini de Oliva, P | 1 |
| Enders, J | 1 |
| Kretschmer, GJ | 1 |
| Sutherland, DE | 1 |
| Matas, AJ | 1 |
| Steffes, MW | 1 |
| Najarian, JS | 1 |
| Leiter, EH | 1 |
| Coleman, DL | 1 |
| Eppig, JJ | 1 |
| Nakagawara, G | 1 |
| Yamasaki, G | 1 |
| Kimura, S | 1 |
| Kojima, Y | 1 |
| Miyazaki, I | 1 |
| Nakama, K | 1 |
| Mohrbacher, RJ | 1 |
| Ho, W | 1 |
| Chempakam, B | 2 |
| Kurup, PA | 5 |
| Wu, CF | 1 |
| Haider, B | 1 |
| Ahmed, SS | 1 |
| Oldewurtel, HA | 1 |
| Lyons, MM | 1 |
| Regan, TJ | 1 |
| Tragl, KH | 1 |
| Jain, RC | 1 |
| Vyas, CR | 1 |
| Ahmed, HM | 1 |
| Román Ramos, R | 1 |
| Lara Lemus, A | 1 |
| Alarcón Aguilar, F | 1 |
| Flores Saenz, JL | 1 |
| Scanes, CG | 1 |
| Wadood, N | 2 |
| Wadood, A | 3 |
| Shah, SA | 2 |
| Mori, K | 1 |
| Kaku, K | 1 |
| Inoue, H | 1 |
| Aoki, M | 1 |
| Matsutani, A | 1 |
| Kaneko, T | 1 |
| Sato, Y | 1 |
| Nishikawa, M | 1 |
| Shinkai, H | 1 |
| Sukegawa, E | 1 |
| Oshiro, K | 1 |
| Murakami, K | 1 |
| Sunagawa, R | 1 |
| Mimura, G | 1 |
| Iwu, MM | 1 |
| Igboko, OA | 1 |
| Okunji, CO | 1 |
| Tempesta, MS | 1 |
| Hussin, AH | 1 |
| Skett, P | 1 |
| Anand, KK | 1 |
| Singh, B | 1 |
| Chand, D | 1 |
| Chandan, BK | 1 |
| Gupta, VN | 1 |
| Philipps, AF | 1 |
| Rosenkrantz, TS | 1 |
| Grunnet, ML | 1 |
| Connolly, ME | 1 |
| Porte, PJ | 1 |
| Raye, JR | 1 |
| Cook, GA | 1 |
| Khan, HH | 1 |
| Noreen, W | 1 |
| Hidayat, HK | 1 |
| Wahid, SA | 1 |
| Babu, BV | 1 |
| Moorti, R | 1 |
| Pugazhenthi, S | 1 |
| Nakagawa, T | 1 |
| Yen, TT | 1 |
| Undie, AS | 1 |
| Akubue, PI | 1 |
| Hosokawa, T | 1 |
| Ando, K | 1 |
| Tamura, G | 1 |
| Begum, H | 1 |
| Bari, MA | 1 |
| Akhtar, MS | 1 |
| Khan, QM | 1 |
| Khaliq, T | 1 |
| Rahman, H | 1 |
| Tyeb, M | 1 |
| Saleemuddin, M | 1 |
| Iwata, H | 1 |
| Baba, A | 1 |
| Baba, T | 1 |
| Nishikawa, T | 1 |
| Foy, JM | 1 |
| Standing, VF | 1 |
| Poser, W | 1 |
| Hasselblatt, A | 2 |
| Schwabe, U | 1 |
| Dean, PM | 1 |
| Matthews, EK | 1 |
| Malathy, K | 3 |
| Saleh, S | 1 |
| Abdel-Khalek, A | 1 |
| Khayyal, MT | 1 |
| Masri, AM | 1 |
| Sharat, AA | 1 |
| Romsos, DR | 1 |
| Leveille, GA | 1 |
| Allee, GL | 1 |
| Mathew, PT | 1 |
| Takasaki, K | 1 |
| Kaneko, M | 1 |
| Fujii, T | 1 |
| Kobayashi, H | 1 |
| Voronkova, LA | 1 |
| Creutzfeldt, W | 1 |
| Loubatières, A | 1 |
| Pemberton, LB | 1 |
| Manax, WG | 1 |
| Kocialski, AB | 1 |
| Marozzi, FJ | 1 |
| Malone, MH | 1 |
| Chaudhury, RR | 1 |
| Bänder, A | 1 |
| Pfaff, W | 2 |
| Schmidt, FH | 1 |
| Stork, H | 1 |
| Schröder, HG | 2 |
| Lundquist, I | 1 |
| Rerup, C | 2 |
| Bauman, N | 1 |
| Gordon, S | 1 |
| Pease, BS | 1 |
| Reissert, K | 1 |
| Rudas, B | 1 |
| Tarding, F | 1 |
| Menahan, LA | 1 |
| Schultz, LH | 1 |
| Hoekstra, WG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Oral Administration of a Herbarium Mixture (Guazuma Ulmifolia and Tecoma Stans) on Metabolic Profile in Type 2 Diabetic Patients[NCT03313856] | Phase 2/Phase 3 | 40 participants (Actual) | Interventional | 2010-01-10 | Completed | ||
| Study of Improving Insulin Sensitivity by Combined Both Electroacupuncture and Drug Therapy[NCT00379379] | 26 participants | Interventional | 2005-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for tolbutamide and Alloxan Diabetes
| Article | Year |
|---|---|
EXPERIMENTAL DIABETES AND THE MODE OF ACTION OF THE SULFONYLUREAS. WITH SOME SPECULATIONS ON THE PREVENTION OF DIABETES.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Cortisone; Diabetes Mellitus; Diabete | 1964 |
The alimentary canal, liver and vagus play a role in short-term feeding: but is the role regulation, correlation, glucostasis or spurious association?
Topics: Animals; Cholecystokinin; Deoxyglucose; Diabetes Mellitus, Experimental; Eating; Feeding Behavior; G | 1984 |
[Current views on the mode of action of hypoglycemic sulfonamides].
Topics: Amino Acids; Animals; Blood Glucose; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus, Experime | 1969 |
[Physiological and pharmacological aspects of the central role of the pancreas in the mode of action of hypoglycemic sulfonamides].
Topics: Action Potentials; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diazoxide; Dogs; Drug An | 1969 |
135 other studies available for tolbutamide and Alloxan Diabetes
| Article | Year |
|---|---|
Sulfonyliminoimidazolidines. A new class of oral hypoglycemic agents. 1. 1-[[p-[2-(acylamino)ethyl]phenyl]sulfonyl]-2-iminoimidazolidines.
Topics: Animals; Biological Assay; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Imid | 1983 |
Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside from Bauhinia forficata leaves.
Topics: Animals; Antioxidants; Bauhinia; Biphenyl Compounds; Blood Glucose; Brazil; Diabetes Mellitus, Exper | 2004 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Profiles of Two Glycaemia Modifying Drugs on the Expression of Rat and Human Sulfotransferases.
Topics: Animals; Biotransformation; Blood Glucose; Diabetes Mellitus, Experimental; Drug Interactions; Hep G | 2021 |
Surface-modified PLGA nanoparticles with chitosan for oral delivery of tolbutamide.
Topics: Administration, Oral; Animals; Blood Glucose; Cell Survival; Chitosan; Diabetes Mellitus, Experiment | 2018 |
Preconditioning with associated blocking of Ca2+ inflow alleviates hypoxia-induced damage to pancreatic β-cells.
Topics: AMP-Activated Protein Kinases; Animals; Calcium; Calcium Channel Blockers; Cell Hypoxia; Cells, Cult | 2013 |
Antihyperglycemic and hypolipidemic effects of Hibiscus schizopetalus (Mast) Hook in alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Hibiscus; Hypoglycemic Age | 2014 |
Cerebrovascular Safety of Sulfonylureas: The Role of KATP Channels in Neuroprotection and the Risk of Stroke in Patients With Type 2 Diabetes.
Topics: Animals; Blotting, Western; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ | 2016 |
Hypoglycemic effect of Mucuna pruriens seed extract on normal and streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hypoglycemic Agents | 2008 |
Antidiabetic activities of Tecoma stans (L.) Juss. ex Kunth.
Topics: Acarbose; Animals; Bignoniaceae; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Female | 2009 |
Influence of Helicteres isora administration for diabetes mellitus: Its effect on erythrocyte membrane and antioxidant status.
Topics: Adenosine Triphosphatases; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Er | 2009 |
Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Blood Glucose; Calcium; Diabetes Mellitus, Experime | 2009 |
2-hydroxy 4-methoxy benzoic acid isolated from roots of Hemidesmus indicus ameliorates liver, kidney and pancreas injury due to streptozotocin-induced diabetes in rats.
Topics: Animals; Benzoic Acid; Diabetes Mellitus, Experimental; Hemidesmus; Hypoglycemic Agents; Kidney; Liv | 2010 |
Hypolipidaemic & hepatoprotective effects of Psidium guajava raw fruit peel in experimental diabetes.
Topics: Animals; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Experimental; Fruit; Hypoglycemic Agents; | 2010 |
Hypoglycemic effect of methanolic extract of Anacardium occidentale leaves in alloxan-induced diabetic rats.
Topics: Alloxan; Anacardium; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; M | 2010 |
Synthesis, antidiabetic and hypolipidemic activities of new diethylamine and triethoxysilyl derivatives of tolbutamide on rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diethylamines; Glyburide; Hypoglycemic Agen | 2012 |
Comparison of the hypoglycemic action of tolbutamide in the fowl and other species.
Topics: Diabetes Mellitus; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Sulfanilamide; Sulfanilamid | 1957 |
The effect of tolbutamide on the diabetogenic action of somatotropin.
Topics: Animals; Diabetes Mellitus, Experimental; Growth Hormone; Human Growth Hormone; Hypoglycemic Agents; | 1959 |
The effect of tolbutamide and insulin on the reduced glutathione content of the blood and liver of normal and alloxan-diabetic rats.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Glutathione; Insulin; Liver; Rats; Tolbutamide | 1961 |
Effects of long-term tolbutamide therapy on severity of diabetes in partially depancreatized rats.
Topics: Animals; Diabetes Mellitus, Experimental; Pancreas; Rats; Tolbutamide | 1960 |
Hypoglycemic drugs and the dextran 'anaphylactoid' inflammation.
Topics: Animals; Dextrans; Diabetes Mellitus, Experimental; Hypersensitivity; Hypoglycemic Agents; Immune Sy | 1960 |
METABOLISM OF THE ALLOXAN DIABETIC RAT RETINA.
Topics: Adrenalectomy; Alloxan; Animals; Chlorpropamide; Diabetes Mellitus, Experimental; Diabetic Retinopat | 1964 |
HISTOLOGICAL CHANGES IN NORMAL AND ALLOXANIZED RATS WITH PROLONGED ADMINISTRATION OF SULFONYLUREAS.
Topics: Adrenal Glands; Animals; Carbutamide; Chlorpropamide; Diabetes Mellitus, Experimental; Islets of Lan | 1963 |
ON THE PRESENCE OF AN ANTIDIABETIC PRINCIPLE IN MOMORDICA CHARANTIA.
Topics: Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Momordica charantia; Pharmacology; Pl | 1963 |
DECREASE IN THE CONCENTRATIONS OF KETONE BODIES AND FREE FATTY ACIDS IN RAT BLOOD IN RESPONSE TO A GLUCOSE LOAD: ITS POSSIBLE RELATION TO ENDOGENOUS INSULIN ACTIVITY.
Topics: Acidosis; Adrenalectomy; Animals; Blood Chemical Analysis; Blood Glucose; Diabetes Mellitus, Experim | 1965 |
The effects of long-term administration of tolbutamide to (alloxan)-subdiabetic rats.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Rats; Tolbutamide | 1959 |
Hypoglycemic effects of Murraya koenigii on normal and alloxan-diabetic rabbits.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Murraya; Phytoth | 2005 |
Evaluation of the hypoglycemic effect and antioxidant activity of three Viscum album subspecies (European mistletoe) in streptozotocin-diabetic rats.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Disease | 2005 |
Hypoglycemic and antihyperglycemic effect of Gmelina asiatica LINN. in normal and in alloxan induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Inte | 2005 |
Improvement of insulin resistance by Acanthopanax senticosus root in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Eleuthe | 2005 |
Hypoglycemic and antiperglycemic effects of Semecarpus anacardium linn in normal and alloxan-induced diabetic rats.
Topics: Administration, Oral; Alloxan; Analysis of Variance; Animals; Antioxidants; Blood Glucose; Diabetes | 2005 |
Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Diterpenes, Kaurane; | 2005 |
Antihyperglycemic effect of the fruit-pulp of Eugenia jambolana in experimental diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fruit; Hypoglycemic Agents; Insulin; Phytot | 2006 |
Antidiabetic and hypolipidaemic effects of a methanol/methylene-chloride extract of Laportea ovalifolia (Urticaceae), measured in rats with alloxan-induced diabetes.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Melli | 2006 |
Effect of Helicteres isora bark extract on blood glucose and hepatic enzymes in experimental diabetes.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Eating; Glycosuria; | 2006 |
Effect of crude extract and fractions from Vitex megapotamica leaves on hyperglycemia in alloxan-diabetic rats.
Topics: Acetates; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hyperglyc | 2007 |
Improvement of insulin resistance by miracle fruit (Synsepalum dulcificum) in fructose-rich chow-fed rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Dose-Respo | 2006 |
Antidiabetic, antioxidant and antihyperlipidemic status of Heliotropium zeylanicum extract on streptozotocin-induced diabetes in rats.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus | 2006 |
Chick pancreatic B islets as an alternative in vitro model for screening insulin secretagogues.
Topics: Animals; Cells, Cultured; Chick Embryo; Chickens; Diabetes Mellitus, Experimental; Female; Hypoglyce | 2006 |
Dioscorea as the principal herb of Die-Huang-Wan, a widely used herbal mixture in China, for improvement of insulin resistance in fructose-rich chow-fed rats.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Carbohydrates | 2007 |
Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced diabetic rats.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Fruit; Glucose Tolerance Test; Glyca | 2007 |
The effects of three oral hypoglycemic agents on the incorporation of leucine-C14 into protein by liver microsomes of normal and alloxan-diabetic rats.
Topics: Animals; Biguanides; Carbon Isotopes; Chlorpropamide; Diabetes Mellitus, Experimental; Female; Leuci | 1967 |
Islet secretion in a new experimental model for non-insulin-dependent diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucagon; Glucos | 1981 |
The effect of glucose and tolbutamide on immunoreactive somatostatin release from perifused pancreatic islets of normal and streptozotocin diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Islets of Lange | 1980 |
Tolbutamide stimulates gastric somatostatin release from isolated perfused rat stomach.
Topics: Animals; Diabetes Mellitus, Experimental; Gastric Mucosa; Glucose; In Vitro Techniques; Male; Perfus | 1982 |
Effect of tolbutamide on insulin, glucagon, and somatostatin release from the diabetic rat pancreas with special reference to glucose concentration.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secreti | 1983 |
Effect of oral antidiabetics on the anaphylactoid reaction.
Topics: Anaphylaxis; Animals; Blood Glucose; Buformin; Dextrans; Diabetes Mellitus, Experimental; Female; Hy | 1981 |
Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas.
Topics: Acetylcholine; Amino Acids; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Gluco | 1983 |
Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 1983 |
Impact of insulin or tolbutamide treatment on 14C-arachidonic acid conversion to prostacyclin and/or thromboxane in lungs, aortas, and platelets of streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Arachidonic Acids; Blood Platelets; Diabetes Mellitus, Experimental; Epoprostenol; I | 1983 |
Effect of the oral hypoglycemic agent pirogliride (McN-3495) on glycogen levels of normal and diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Fasting; Glycogen; Hypoglycemic Agents; Insulin; Kinetics; | 1983 |
[Hypoglycemic effects of the blended Chinese traditional medicines in genetically and chemically diabetic mice].
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic Agents; Ma | 1984 |
Effect of tolbutamide on myocardial metabolism and mechanical performance of the diabetic rat.
Topics: Animals; Cardiac Output; Diabetes Mellitus, Experimental; Glucose; Heart; Kinetics; Lactates; Lactic | 1984 |
Serum glycohydrolases in compensated & decompensated alloxan diabetic rabbits.
Topics: Animals; Diabetes Mellitus, Experimental; Glyburide; Glycoside Hydrolases; Insulin; Kinetics; Male; | 1981 |
Effects of D-mannoheptulose on blood glucose and alloxan sensitivity in mice.
Topics: Alloxan; Animals; B-Lymphocytes; Blood Glucose; Diabetes Mellitus, Experimental; Female; Heptoses; H | 1980 |
Oral glucose tolerance test in normal sympathectomized & streptozotocin induced diabetic rhesus monkeys: effect on plasma immunoreactive insulin, free fatty acids & blood lactate.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Insulin; Lactates; | 1980 |
Effect of oral hypoglycemic drugs on heart norepinephrine (NE) in rats and mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Induction; Female; Hypoglycemic Agen | 1982 |
[Effect of circulating insulin on liver damage by CCl4 in the rat. II. Histological aspects].
Topics: Animals; Carbon Tetrachloride Poisoning; Diabetes Mellitus, Experimental; Hyperinsulinism; Liver; Ra | 1980 |
Effect of D-400, a herbal formulation, on blood sugar of normal and alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Epinephrine; Fasting; | 1995 |
Hypoglycemic effect of Ocimum sanctum leaf extract in normal and streptozotocin diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Male; Plant Ex | 1993 |
Hypoglycemic activity of polygonati rhizoma in normal and diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Epinephrine; Glucose Tolerance Test; Glycog | 1993 |
Potentiating effects of combined usage of three sulfonylurea drugs on the occurrence of alloxan diabetes in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Combinations; Drug Synergism; Gliclazi | 1993 |
The inhibitory action of buformin, a biguanide on gluconeogenesis from alanine and its transport system in rat livers.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Biological Transport, Active; Buformin; Cell | 1993 |
Diminished fraction of blockable ATP-sensitive K+ channels in islets transplanted into diabetic mice.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cytosol; Diabetes Mellitus, Experimental; Gluco | 1996 |
Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucose Tolerance Test; Hypoglycemi | 1997 |
Nongenetic mouse models of non-insulin-dependent diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Di | 1998 |
Study of the anti-hyperglycemic effect of plants used as antidiabetics.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glucose Tolerance Test; Hyperglyce | 1998 |
Impaired phasic insulin and amylin secretion in diabetic rats.
Topics: Activity Cycles; Amyloid; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose | 1998 |
An insulin-dependent hypoglycaemia induced by electroacupuncture at the Zhongwan (CV12) acupoint in diabetic rats.
Topics: Acupuncture Points; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Diabete | 1999 |
JTT-608 controls blood glucose by enhancement of glucose-stimulated insulin secretion in normal and diabetes mellitus rats.
Topics: Administration, Oral; Animals; Animals, Newborn; Blood Glucose; Butyrates; Cyclohexanes; Diabetes Me | 1999 |
Effect of Punica granatum Linn. (flowers) on blood glucose level in normal and alloxan-induced diabetic rats.
Topics: Animals; Behavior, Animal; Blood Glucose; Diabetes Mellitus, Experimental; Fasting; Female; Glucose | 2000 |
Effect of Cirsium pascuarense on blood glucose levels of normoglycaemic and alloxan-diabetic mice.
Topics: Alloxan; Animals; Asteraceae; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; M | 2001 |
A pharmacologic profile of McN-3495 [N-(1-methyl-2-pyrrolidinylidene)-N'-phenyl-1-pyrrolidinecarboximidamide], a new, orally effective hypoglycemic agent.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Drug Evaluation, Preclinical; Female; | 1978 |
Effects of insulin on plasma fibrinogen levels in rats submitted to tissue injury or ACTH administration.
Topics: Adrenocorticotropic Hormone; Animals; Diabetes Mellitus, Experimental; Female; Fibrinogen; Insulin; | 1979 |
The dispersed pancreas: transplantation without islet purification in totally pancreatectomized dogs.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucose Tolerance Test; Pancreas; Pan | 1977 |
Endocrine pancreatic cells of postnatal "diabetes" (db) mice in cell culture.
Topics: Animals; Cell Differentiation; Culture Techniques; Cytoplasmic Granules; Diabetes Mellitus, Experime | 1979 |
Insulin-releasing activity and successful transplantation of pancreatic islets preserved by tissue culture.
Topics: Animals; Culture Techniques; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Se | 1978 |
Differences in the blood glucose response of mice to alloxan and alloxan-inhibiting compounds.
Topics: Acetazolamide; Alloxan; Animals; Bicarbonates; Blood Glucose; Deoxy Sugars; Diabetes Mellitus, Exper | 1979 |
Studies on diabetic syndrome and influences of long-term tolbutamide administration in Mongolian gerbils (Meriones unguiculatus).
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Ge | 1977 |
Pharmacologic profile of methyl 2-tetradecylglycidate (McN-3716)--an orally effective hypoglycemic agent.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Fats; Dogs; Dose-Response Relations | 1978 |
Effect of administration of insulin, tolbutamide & phenformin on tissue glycoproteins in alloxan diabetic rabbits.
Topics: Animals; Aorta; Cartilage; Diabetes Mellitus, Experimental; Glycoproteins; Insulin; Male; Phenformin | 1978 |
Stability of lysosomes in tissues of alloxan diabetic rabbits & effect of administration of insulin, tolbutamide & phenformin.
Topics: Animals; Diabetes Mellitus, Experimental; Glucuronidase; Insulin; Lysosomes; Male; Phenformin; Rabbi | 1978 |
The effects of tolbutamide on the myocardium in experimental diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Heart; Hemody | 1977 |
[On the influence of oral antidiabetics on protein biosynthesis in vitro (author's transl)].
Topics: Animals; Buformin; Centrifugation, Density Gradient; Diabetes Mellitus, Experimental; Hypoglycemic A | 1976 |
Garlic in alloxan-induced diabetic rabbits.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fasting; Garlic; Hypogly | 1975 |
Effect of calcium chloride on some metabolic actions of certain antidiabetic drugs in normal and alloxanised rabbits.
Topics: Animals; Calcium Chloride; Diabetes Mellitus, Experimental; Drug Antagonism; Drug Synergism; Insulin | 1975 |
Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes.
Topics: Allyl Compounds; Animals; Blood Glucose; Caseins; Diabetes Mellitus, Experimental; Disulfides; Glyco | 1975 |
Hypoglycemic activity of some antidiabetic plants.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Hyperglycemia; Hypoglycemic | 1992 |
Lipolytic and diabetogenic effects of native and biosynthetic growth hormone in the chicken: a re-evaluation.
Topics: Animals; Blood Glucose; Chickens; Corticosterone; Diabetes Mellitus, Experimental; Fatty Acids, None | 1992 |
Effect of Tinospora cordifolia on blood glucose and total lipid levels of normal and alloxan-diabetic rabbits.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Lipids; Male; Plant Extracts; Plants, Medic | 1992 |
Effects of tolbutamide on fructose-2,6-bisphosphate formation and ketogenesis in hepatocytes from diabetic rats.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fructosediphosphates | 1992 |
Possibility of ideal blood glucose control by a new oral hypoglycemic agent, N-[(trans-4-isopropylcyclohexyl)-carbonyl]-D-phenylalanine (A-4166), and its stimulatory effect on insulin secretion in animals.
Topics: Animals; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Experimental; Dogs; Glucose Tolerance Test; | 1991 |
Chronic effects of tolbutamide on myocardial tension during ischemia and reperfusion in perfused hearts isolated from insulin dependent and non insulin dependent diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitu | 1991 |
Antidiabetic and aldose reductase activities of biflavanones of Garcinia kola.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Flavonoids; Hypoglycemi | 1990 |
The potentiating effect of the simultaneous administration of tolbutamide, glibenclamide, and gliclazide on the development of alloxan-induced diabetes in rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drug Synergism; Gliclazide; Gl | 1990 |
The interaction of oral hypoglycaemic drugs with insulin on steroid metabolism in hepatocytes isolated from control and diabetic male rats.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Insul | 1990 |
Effect of a single administration of tolbutamide on the occurrence of alloxan diabetes in rats.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Dr | 1990 |
Effect of Zizyphus sativa leaves on blood glucose levels in normal and alloxan-diabetic rats.
Topics: Animals; Behavior, Animal; Blood Glucose; Diabetes Mellitus, Experimental; India; Male; Plant Extrac | 1989 |
Effects of fetal insulin secretory deficiency on metabolism in fetal lamb.
Topics: Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Fetal Blood; Fetus; Hyper | 1986 |
Potentiating effect of glibenclamide on the occurrence of alloxan diabetes in rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Glyburide; Male; R | 1986 |
The hypoglycemic sulfonylureas glyburide and tolbutamide inhibit fatty acid oxidation by inhibiting carnitine palmitoyltransferase.
Topics: Acyltransferases; Animals; Carnitine O-Palmitoyltransferase; Diabetes Mellitus, Experimental; Fatty | 1987 |
Effect of Eriobotrya japonica on blood glucose levels of normal and alloxan diabetic rabbits.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Male; Plant Extracts; Plants, Medicinal; Ra | 1988 |
Effect of Eriobotrya japonica on blood glucose levels of normal and alloxan-diabetic rabbits.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Male; Plant Extracts; Rabbits; Tolbutamide | 1988 |
Alloxan recovered rabbits as animal model for screening for hypoglycaemic activity of compounds.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Hypoglycemic Agents; Male; P | 1988 |
Effect of fasting upon the potentiating effect of tolbutamide on the occurrence of alloxan diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Fasting; Insulin; Male; Pancreas; Rats; Rats, Inbred Strai | 1986 |
MTP-1307, a novel antidiabetic agent, improves the glucose intolerance of viable yellow obese-diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fasting; Glucose Toleran | 1987 |
Pharmacological evaluation of Dioscorea dumetorum tuber used in traditional antidiabetic therapy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Medicine, Traditional; | 1986 |
An ascochlorin derivative, AS-6, reduces insulin resistance in the genetically obese diabetic mouse, db/db.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drinking; | 1985 |
Effect of garlic oil on the pancreas of experimental diabetes in guineapigs.
Topics: Allyl Compounds; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Female; Garli | 1985 |
Effects of Portulaca oleracae (Kulfa) and Taraxacum officinale (Dhudhal) in normoglycaemic and alloxan-treated hyperglycaemic rabbits.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hyperglycemia; Male; Pakistan; Plant Extrac | 1985 |
Hypoglycemic activity of Tephrosea purpurea Linn. seeds.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Male; Plant Extracts; Rabbits | 1985 |
Glucose intolerance in thiamine-deficient rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Insulin; Rats; Thia | 1974 |
The effect of glibenclamide on non-esterified fatty acid levels in the plasma of the severely alloxan diabetic rat.
Topics: Animals; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; | 1973 |
[The blood sugar lowering effect of sulfafurazole and sulfamethoxazole in the rat].
Topics: Animals; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hepatectomy; Hypoglycemia; Mal | 1969 |
[Inhibition of ketogenesis in liver tissue by tolbutamide and glycodiazine in vitro].
Topics: Acetates; Acetoacetates; Animals; Carbon Isotopes; Depression, Chemical; Diabetes Mellitus, Experime | 1969 |
The bioelectrical properties of pancreatic islet cells: effects of diabetogenic agents.
Topics: Action Potentials; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Female; | 1972 |
Effect of administration of insulin and tolbutamide on the glycosaminoglycan levels in diabetic rat tissues.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Glycosaminoglycans; Insulin; Kidney; Male; Rats; Re | 1973 |
Studies on the effect of oral hypoglycaemic agents on hepatic glycogenolysis.
Topics: Acetohexamide; Animals; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Experimental; Glucos | 1974 |
Alloxan diabetes in the pig (Sus domesticus). Response to glucose, tolbutamide and insulin administration.
Topics: Acetoacetates; Ammonium Chloride; Animals; Antigens; Blood Glucose; Body Weight; Diabetes Mellitus, | 1971 |
Metabolism of glycosaminoglycans in alloxan diabetic rats--hepatic UDPG pyrophosphorylase activity.
Topics: Alcohol Oxidoreductases; Animals; Diabetes Mellitus, Experimental; Enzyme Activation; In Vitro Techn | 1972 |
Tissue lipid pattern, tissue lipoprotein lipase activity and effect of administration of insulin and tolbutamide on the tissue lipid levels in alloxan diabetic rats.
Topics: Animals; Cholesterol; Diabetes Mellitus, Experimental; Insulin; Lipids; Lipoprotein Lipase; Liver; M | 1972 |
Studies on the effects of a hypoglycemic principle from Allium Cepa Linn.
Topics: Animals; Biological Assay; Blood Glucose; Depression, Chemical; Diabetes Mellitus, Experimental; Ins | 1973 |
Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes. I. Hypoglycaemic action and enhancement of serum insulin effect and glycogen synthesis.
Topics: Administration, Oral; Allyl Compounds; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Garl | 1973 |
[Hypoglycemic action of certain heterocyclic carboxylic acid derivatives].
Topics: Adrenal Glands; Animals; Blood Glucose; Carboxylic Acids; Diabetes Mellitus, Experimental; Dogs; Epi | 1973 |
[Comparative characteristics of the hypoglycemic effect of a new 3,5-dioxopyrazolidine derivative, DSB, and butamide].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemia; Hypoglycemic Agents; Pyrazole | 1973 |
Control of alloxan diabetes in dogs by islet cell transplantation.
Topics: Animals; Atrophy; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Gluc | 1971 |
Effects of certain nonsteroid anti-inflammatory drugs, tolbutamide, and tetrahydroalstonine on blood glucose and carrageen in-induced pedal edema in rats.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Blood Glucose; Carrageenan; Chlorpromazine; Diabetes M | 1972 |
Response of a diabetic strain of mouse to oral tolbutamide.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Mice; Tolbutamide | 1968 |
[Pharmacology of HB 419, a new strongly effective oral antidiabetic].
Topics: Adrenalectomy; Animals; Blood Glucose; Carbutamide; Chlorpropamide; Depression, Chemical; Diabetes M | 1969 |
[Effect of HB 419 on exogenous and endogenous insulin in dogs and rabbits].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Hypoglycemic Agents; Insulin; Male; P | 1969 |
On the development of alloxan diabetes in mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Guinea Pigs; Hyperglycemia; Immune | 1967 |
Indole-2-carboxylic acids, a new class of hypoglycemic compounds.
Topics: Acids; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Indoles; Male; | 1969 |
[Effect of antidiabetics on the fat metabolism of alloxan-diabetic rats].
Topics: Animals; Chronic Disease; Depression, Chemical; Diabetes Mellitus, Experimental; Fatty Acids, Nonest | 1969 |
Streptozotocin- and alloxan-diabetes in mice.
Topics: Animals; Anti-Bacterial Agents; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Ex | 1969 |
Relationship of ketone body metabolism and carbohydrate utilization to fat mobilization in the ruminant.
Topics: Animals; Blood Glucose; Cattle; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Fats; Fatty | 1966 |