Compounds > tolbutamide
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tolbutamide and Alcoholism

tolbutamide has been researched along with Alcoholism in 39 studies

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)

Research Excerpts

ExcerptRelevanceReference
" over forty minutes) on plasma pancreatic glucagon-like immunoreactivity (PGLI), serum insulin, and blood glucose were studied in six patients with chronic pancreatitis and six matched controls."7.65Immunoreactive glucagon responses to intravenous tolbutamide in chronic pancreatitis. ( Jackson, WP; Kalk, WJ; Leller, P; Paul, M; Vinik, AI, 1975)
" over forty minutes) on plasma pancreatic glucagon-like immunoreactivity (PGLI), serum insulin, and blood glucose were studied in six patients with chronic pancreatitis and six matched controls."3.65Immunoreactive glucagon responses to intravenous tolbutamide in chronic pancreatitis. ( Jackson, WP; Kalk, WJ; Leller, P; Paul, M; Vinik, AI, 1975)
"A case of hypoglycemic coma after alcohol ingestion was observed in a chronic alcoholic."1.26Isolated corticotrophin-deficiency found through alcohol-induced hypoglycemic coma. ( Baba, S; Hishida, S; Mizoi, Y; Morita, S; Takase, S; Uenoyama, R, 1976)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199039 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
COHN, HJ1
PERLMUTTER, M1
SILVERSTEIN, JN1
NUMEROFF, M1
MARKS, V1
MEDD, WE1
KAHIL, ME1
BROWN, H1
DOBSON, HL1
MOORHEAD, HH1
MCKINLEY, RA1
ROBERTS, HJ1
GEBBIE, T1
REID, JD1
DeMoura, MC1
Correia, JP1
Madeira, F1
Petersen, DR1
Hjelle, JJ1
Goldberg, DM1
Baba, S1
Takase, S1
Uenoyama, R1
Morita, S1
Mizoi, Y1
Hishida, S1
Peña Yáñez, A1
López Luque, A1
Osorio, J1
del Arbol, L1
Rico Irles, J1
Palomo, S1
Hed, R4
Nygren, A4
Röjdmark, S2
Sundblad, L3
Mütting, D1
Kaufmann, M1
Iber, FL5
Thiessen, JJ1
Sellers, EM1
Denbeigh, P1
Dolman, L1
Kalk, WJ1
Vinik, AI1
Paul, M1
Leller, P1
Jackson, WP1
Chvíla, L1
Kostelnik, ME1
Steer, P1
Marnell, R1
Werk, EE1
De Matteis, F1
Caquet, R1
Horowitz, SH1
Johnson, BF1
Hausmann, L1
Schubotz, R1
Born, H1
Kaffarnik, H1
Gundert-Remy, U1
Marquardt, R1
Andritsch, F1
Weber, E1
Müller, MM1
Frank, O1
Knick, B1
Kater, RM2
Roggin, G1
Tobon, F2
Zieve, P1
Berkowitz, D1
Shah, MN1
Clancy, BA1
Erwald, R1
Wiechel, KL1
Manenti, F1
Carulli, N1
Agnolucci, MT1
Coppo, M1
Fourlinnie, JC1
Bedoret, JM1
Duc-Cuvelier, MF1
Caridroit, M1
Fontan, M1
Linquette, M1
Fuchs, T1
Immich, H1
Nedden, R1
Rhomberg, HP1
Bank, S1

Reviews

4 reviews available for tolbutamide and Alcoholism

ArticleYear
ALCOHOLISM.
    Progress in neurology and psychiatry, 1963, Volume: 18

    Topics: Alcoholism; Chlordiazepoxide; Chlormethiazole; Chlorpropamide; Culture; Lysergic Acid Diethylamide;

1963
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
    Clinical chemistry, 1980, Volume: 26, Issue:6

    Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; E

1980
Toxic hepatic porphyrias.
    Seminars in hematology, 1968, Volume: 5, Issue:4

    Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyc

1968
[Current problems of fatty liver].
    Deutsches medizinisches Journal, 1968, May-15, Volume: 19, Issue:10

    Topics: Alcoholism; Diabetes Complications; Fatty Liver; Humans; Liver; Obesity; Tolbutamide

1968

Trials

2 trials available for tolbutamide and Alcoholism

ArticleYear
Increased rate of clearance of drugs from the circulation of alcoholics.
    The American journal of the medical sciences, 1969, Volume: 258, Issue:1

    Topics: Alcoholism; Clinical Trials as Topic; Ethanol; Humans; Liver; Microsomes; Phenytoin; Tolbutamide; Wa

1969
Glucose tolerance, free fatty acid, and serum insulin responses in patients with cirrhosis.
    The American journal of digestive diseases, 1969, Volume: 14, Issue:10

    Topics: Adult; Alcoholism; Blood Glucose; Clinical Trials as Topic; Fatty Acids, Nonesterified; Female; Gluc

1969

Other Studies

33 other studies available for tolbutamide and Alcoholism

ArticleYear
PROLONGED HYPOGLYCEMIA IN RESPONSE TO INTRAVENOUS TOLBUTAMIDE IN A PATIENT WITH LAENNEC'S CIRRHOSIS AND SEVERE MALNUTRITION.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Alcoholism; Glucose Tolerance Test; Humans; Hypoglycemia; Injections; Injections, Intravenous; Liver

1964
ALCOHOL-INDUCED HYPOGLYCAEMIA.
    The British journal of psychiatry : the journal of mental science, 1964, Volume: 110

    Topics: Alcoholism; Blood Chemical Analysis; Blood Glucose; Ethanol; Glucagon; Humans; Hypoglycemia; Liver F

1964
POSTALCOHOLIC HYPOGLYCEMIA VERSUS ISLET CELL TUMOR.
    Gastroenterology, 1964, Volume: 46

    Topics: Adenoma, Islet Cell; Alcoholism; Diagnosis, Differential; Glucose Tolerance Test; Humans; Hypoglycem

1964
AFTERNOON GLUCOSE TOLERANCE TESTING: A KEY TO THE PATHOGENESIS, EARLY DIAGNOSIS AND PROGNOSIS OF DIABETOGENIC HYPERINSULINISM.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Adolescent; Alcoholism; Black People; Cortisone; Diabetes Mellitus; Diet; Diet Therapy; Early Diagno

1964
EFFECT OF TOLBUTAMIDE IN CLEARING INDUCED ALIMENTARY LIPAEMIA AFTER ALCOHOLIC HEPATOPANCREATIC DAMAGE.
    Lancet (London, England), 1964, Sep-26, Volume: 2, Issue:7361

    Topics: Alcoholism; Blood Glucose; Dietary Fats; Fatty Acids; Glycerides; Hyperlipidemias; Injections, Intra

1964
Clinical alcohol hypoglycemia.
    Annals of internal medicine, 1967, Volume: 66, Issue:5

    Topics: Aged; Alcoholic Intoxication; Alcoholism; Blood Glucose; Ethanol; Fasting; Female; Glucagon; Glucose

1967
Metabolic interactions of aldehyde dehydrogenase with therapeutic and toxic agents.
    Progress in clinical and biological research, 1982, Volume: 114

    Topics: Alcohol Oxidoreductases; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Anti

1982
Isolated corticotrophin-deficiency found through alcohol-induced hypoglycemic coma.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1976, Volume: 8, Issue:4

    Topics: Adrenocorticotropic Hormone; Alcoholism; Coma; Galactose; Glucagon; Glucose Tolerance Test; Humans;

1976
[Insulin reserve in chronic alcoholics without pancreatitis and hepatic cirrhosis. Etiological role of alcohol in diabetes].
    Revista clinica espanola, 1978, Volume: 150, Issue:1-2

    Topics: Adult; Aged; Alcoholism; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Humans;

1978
Does a disturbed insulin release promote hypoglycemia in alcoholics?
    Acta medica Scandinavica, 1978, Volume: 204, Issue:1-2

    Topics: Adult; Alcoholism; Fasting; Glucose Tolerance Test; Humans; Hypoglycemia; Injections, Intravenous; I

1978
[Disorders of glucose tolerance in 2600 histologically confirmed acute and chronic liver patients (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Oct-17, Volume: 117, Issue:42

    Topics: Acute Disease; Administration, Oral; Alcoholism; Chronic Disease; Diabetes Complications; Fatty Live

1975
Drug metabolism in heavy consumers of ethyl alcohol.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:5 Pt 2

    Topics: Adult; Alcohol Drinking; Alcoholism; Aminopyrine; Chemical and Drug Induced Liver Injury; Humans; Li

1977
Plasma protein binding of diazepam and tolbutamide in chronic alcoholics.
    Journal of clinical pharmacology, 1976, Volume: 16, Issue:7

    Topics: Alcoholism; Blood Proteins; Chemical and Drug Induced Liver Injury; Chronic Disease; Diazepam; Femal

1976
Immunoreactive glucagon responses to intravenous tolbutamide in chronic pancreatitis.
    Diabetes, 1975, Volume: 24, Issue:9

    Topics: Adult; Alcoholism; Blood Glucose; Chronic Disease; Glucagon; Humans; Insulin; Male; Middle Aged; Pan

1975
[Changes in glucose metabolism in persons dependent on alcohol].
    Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum, 1987, Volume: 30, Issue:2

    Topics: Adult; Alcoholism; Glucose; Humans; Male; Tolbutamide

1987
Correlation of alcohol and tolbutamide blood clearance rates with microsomal alcohol-metabolizing enzyme activity.
    The American journal of clinical nutrition, 1973, Volume: 26, Issue:2

    Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Biopsy; Chronic Disease; Ethanol; Half-Life; Humans; Inj

1973
Insulin response in chronic alcoholism.
    Lancet (London, England), 1968, Jan-20, Volume: 1, Issue:7534

    Topics: Alcoholism; Blood Glucose; Carbohydrate Metabolism; Glucose Tolerance Test; Humans; Hyperinsulinism;

1968
Clinical alcohol hypoglycemia and isolated adrenocorticotrophic hormone deficiency.
    Annals of internal medicine, 1969, Volume: 71, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Blood Glucose; Coma; Deficiency Diseases; Ethanol; G

1969
[Alcoholic hypoglycemia in adults].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Nov-14, Volume: 44, Issue:47

    Topics: Adult; Alcoholism; Diet; Glucagon; Glucose Tolerance Test; Hepatic Encephalopathy; Humans; Hypoglyce

1968
[Spontaneous hypoglycemias in adults].
    La Presse medicale, 1969, May-28, Volume: 77, Issue:26

    Topics: Addison Disease; Adenoma; Adenoma, Islet Cell; Adrenal Insufficiency; Adult; Alcoholism; Blood Gluco

1969
The efficacy of oral tolbutamide in chronic alcoholics.
    The American journal of the medical sciences, 1972, Volume: 264, Issue:5

    Topics: Adult; Alcoholism; Drug Interactions; Ethanol; Humans; Hypoglycemia; Male; Tolbutamide

1972
[Carbohydrate tolerance and insulin secretion in patients with fatty liver].
    Schweizerische medizinische Wochenschrift, 1972, Jul-14, Volume: 103, Issue:28

    Topics: Adult; Aged; Alcoholism; Antigens; Diabetes Mellitus; Fatty Liver; Female; Glucose Tolerance Test; H

1972
[Induction of drug-catabolizing enzymes in chronic alcoholics].
    Archives of biochemistry and biophysics, 1974, Volume: 160, Issue:1

    Topics: Alcoholism; Antipyrine; Chronic Disease; Enzyme Induction; Humans; Microsomes, Liver; Pharmaceutical

1974
Lipid and purine metabolism in benign symmetric lipomatosis.
    Advances in experimental medicine and biology, 1974, Volume: 41

    Topics: Adult; Alcohol Drinking; Alcoholism; Blood Glucose; Blood Protein Electrophoresis; Carbon Radioisoto

1974
Comparison of blood clearance of ethanol and tolbutamide and the activity of hepatic ethanol-oxidizing and drug-metabolizing enzymes in chronic alcoholic subjects.
    The American journal of clinical nutrition, 1972, Volume: 25, Issue:2

    Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Aniline Compounds; Chronic Disease; Ethanol; Half-Life;

1972
Immunoreactive insulin in the portal and the peripheral venous blood after intravenous tolbutamide administration.
    Diabetes, 1971, Volume: 20, Issue:10

    Topics: Adult; Aged; Alanine Transaminase; Alcoholism; Alkaline Phosphatase; Antigen-Antibody Reactions; Asp

1971
[The liver and alcohol. Results of our research].
    Revue medico-chirurgicale des maladies du foie, 1971, Volume: 46, Issue:6

    Topics: Adult; Alcohol Oxidoreductases; Alcoholic Intoxication; Alcoholism; Animals; Chemical and Drug Induc

1971
[Variations of glycemia and insulinemia induced by glucose and tolbutamide in chronic alcoholics].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1970, Volume: 15, Issue:5

    Topics: Alcoholism; Blood Glucose; Chronic Disease; Female; Glucose; Humans; Insulin; Male; Tolbutamide

1970
[Quantitative relations between sero-chemical findings, fatty degeneration of the liver, alcohol drinking and body weight in a diabetic and non-diabetic collective with fatty degeneration of the liver].
    Die Medizinische Welt, 1971, Mar-06, Volume: 10

    Topics: Alanine Transaminase; Alcoholism; Body Weight; Diabetes Complications; Electrophoresis; Fatty Liver;

1971
[Dupuytren's contracture and internal diseases].
    Wiener klinische Wochenschrift, 1967, Oct-27, Volume: 79, Issue:43

    Topics: Adult; Age Factors; Aged; Alcoholism; Diabetes Complications; Dupuytren Contracture; Electrophoresis

1967
Alcohol-induced hypoglycaemia in chronic alcoholics with liver disease.
    Acta medica Scandinavica, 1968, Volume: 183, Issue:6

    Topics: Adult; Alcoholism; Blood Glucose; Carbohydrates; Diabetes Mellitus; Fasting; Fatty Liver; Female; Gl

1968
Increased rate of tolbutamide metabolism in alcoholic patients.
    JAMA, 1969, Jan-13, Volume: 207, Issue:2

    Topics: Adolescent; Adult; Alcoholism; Ethanol; Female; Humans; Liver; Male; Microsomes; Middle Aged; Tolbut

1969
The management of diabetes in the underprivileged, with special reference to pancreatic diabetes.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1966, Apr-23, Volume: 40, Issue:15

    Topics: Africa, Southern; Alcoholism; Black or African American; Black People; Diabetes Mellitus; Diet, Diab

1966