tolbutamide has been researched along with Adverse Drug Event in 12 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Dawson, S | 1 |
| Stahl, S | 1 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Sharma, A | 1 |
| Pagidipati, NJ | 1 |
| Califf, RM | 1 |
| McGuire, DK | 1 |
| Green, JB | 1 |
| Demets, D | 1 |
| George, JT | 1 |
| Gerstein, HC | 1 |
| Hobbs, T | 1 |
| Holman, RR | 1 |
| Lawson, FC | 1 |
| Leiter, LA | 1 |
| Pfeffer, MA | 1 |
| Reusch, J | 1 |
| Riesmeyer, JS | 1 |
| Roe, MT | 1 |
| Rosenberg, Y | 1 |
| Temple, R | 1 |
| Wiviott, S | 1 |
| McMurray, J | 1 |
| Granger, C | 1 |
| Rümke, CL | 1 |
| Domula, M | 1 |
| Weissbach, G | 1 |
| Lenk, H | 1 |
| Keller, J | 1 |
| Eipe, J | 1 |
| Moses, AM | 1 |
| Miller, M | 1 |
| Kewitz, H | 1 |
| de Matteis, F | 1 |
| Ratzenhofer, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria[NCT03906214] | 60 participants (Actual) | Observational | 2019-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for tolbutamide and Adverse Drug Event
| Article | Year |
|---|---|
Drugs affecting therapy with anticoagulants.
Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Intera | 1972 |
Drug-induced dilutional hyponatremia.
Topics: Acetaminophen; Amitriptyline; Animals; Anura; Body Fluids; Carbamazepine; Chlorpropamide; Clofibrate | 1974 |
Disturbances of liver porphyrin metabolism caused by drugs.
Topics: Animals; Chlorpropamide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Griseofulvin; H | 1967 |
9 other studies available for tolbutamide and Adverse Drug Event
| Article | Year |
|---|---|
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug-Related Side Effects and Adverse Reactions; | 2020 |
[Objectionable conservatism or sensible policy in pharmacotherapy?].
Topics: Central Nervous System Stimulants; Child; Clioquinol; Diethylstilbestrol; Drug-Related Side Effects | 1976 |
[Effect of drug therapy during pregnancy on the clotting potential of the newborn].
Topics: Aspirin; Blood Coagulation Disorders; Drug-Related Side Effects and Adverse Reactions; Female; Hemos | 1977 |
[Drugs as causes of diseases].
Topics: Adult; Aged; Contraceptives, Oral; Drug-Related Side Effects and Adverse Reactions; Female; Humans; | 1973 |
[Side-effects and fatal outcome of drug therapy. Pathological and anatomical experiences during the past 18 years in Styrial].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Amines; Analgesics; Anaphylaxis; Anti-Bacterial Ag | 1972 |