tolbutamide has been researched along with Adenomatosis, Familial Endocrine in 7 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The data indicate: 1) insulin-secreting islet cell tumors have decreased storage capacity for insulin, 2) elevated concentration of proinsulin in tumors may be due to decreased capacity to store insulin and in some to decreased conversion of proinsulin to insulin as well, 3) tolbutamide stimulates the exaggerated release of a relatively constant fraction of insulin stored in adenomas." | 5.26 | Insulin, proinsulin, glucagon and gastrin in pancreatic tumors and in plasma of patients with organic hyperinsulinism. ( Fajans, SS; Floyd, JC; Hayashi, M; Pek, S, 1977) |
| "The data indicate: 1) insulin-secreting islet cell tumors have decreased storage capacity for insulin, 2) elevated concentration of proinsulin in tumors may be due to decreased capacity to store insulin and in some to decreased conversion of proinsulin to insulin as well, 3) tolbutamide stimulates the exaggerated release of a relatively constant fraction of insulin stored in adenomas." | 1.26 | Insulin, proinsulin, glucagon and gastrin in pancreatic tumors and in plasma of patients with organic hyperinsulinism. ( Fajans, SS; Floyd, JC; Hayashi, M; Pek, S, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| UNDERWOOD, LE | 1 |
| JACOBS, NM | 1 |
| Hayashi, M | 1 |
| Floyd, JC | 1 |
| Pek, S | 1 |
| Fajans, SS | 1 |
| Tragl, KH | 1 |
| Mayr, WR | 1 |
| Vance, JE | 4 |
| Kitabchi, AE | 3 |
| Buchanan, KD | 2 |
| Stoli, RW | 1 |
| Hollander, D | 2 |
| Wood, FC | 2 |
| Stoll, RW | 3 |
| Williams, RH | 3 |
| Fariss, BL | 1 |
7 other studies available for tolbutamide and Adenomatosis, Familial Endocrine
| Article | Year |
|---|---|
FAMILIAL ENDOCRINE ADENOMATOSIS. A FAMILY WITH HYPERINSULINISM AS THE PREDOMINANT MANIFESTATION.
Topics: Adenoma; Adenoma, Islet Cell; Adolescent; Carcinoma, Bronchogenic; Child; Clinical Laboratory Techni | 1963 |
Insulin, proinsulin, glucagon and gastrin in pancreatic tumors and in plasma of patients with organic hyperinsulinism.
Topics: Adenoma; Adenoma, Islet Cell; Adolescent; Adult; Aged; Antigen-Antibody Reactions; Carcinoma; Female | 1977 |
Familial islet-cell adenomatosis.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Diabetes Complications; Female; Glucagon; HLA Antigens; H | 1977 |
Hypersecretion of insulin, glucagon and gastrin in a kindred with multiple adenomatosis.
Topics: Adenoma, Islet Cell; Adrenal Gland Diseases; Gastrins; Glucagon; Glucose Tolerance Test; Humans; Hyp | 1968 |
Nesidioblastosis in familial endocrine adenomatosis.
Topics: Adrenal Gland Neoplasms; Adult; Child; Gastrins; Glucagon; Glucose Tolerance Test; Humans; Insulin; | 1969 |
Familial nesidioblastosis as the predominant manifestation of multiple endocrine adenomatosis.
Topics: Adenoma, Islet Cell; Adolescent; Adult; Aged; Diazoxide; Female; Gastric Mucosa; Gastrins; Glucagon; | 1972 |
Exaggerated intestinal glucagon and insulin responses in human subjects.
Topics: Administration, Oral; Blood Glucose; Female; Gastrectomy; Glucagon; Glucose Tolerance Test; Humans; | 1972 |