Page last updated: 2024-11-05

tolbutamide and Adenoma, alpha-Cell

tolbutamide has been researched along with Adenoma, alpha-Cell in 4 studies

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Research Excerpts

ExcerptRelevanceReference
" This study investigated the interactions of calcium and somatostatin analogues on peptide release in two patients, one with a glucagonoma (patient A) and one with an insulinoma (patient B)."9.08Calcium reverses octreotide inhibition of insulin and glucagon levels in patients with insulinoma and glucagonoma. ( O'Dorisio, TM; Thompson, CS; Woltering, EA, 1996)
"Thus, alpha-TC glucagonoma cells contain ATP-sensitive K+ channels that regulate glucagon release, yet allow inhibition of hormone release by glucose."5.29Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. ( Buettger, C; Epstein, AJ; Hang, TL; Matschinsky, FM; Ronner, P, 1993)
" This study investigated the interactions of calcium and somatostatin analogues on peptide release in two patients, one with a glucagonoma (patient A) and one with an insulinoma (patient B)."5.08Calcium reverses octreotide inhibition of insulin and glucagon levels in patients with insulinoma and glucagonoma. ( O'Dorisio, TM; Thompson, CS; Woltering, EA, 1996)
"Thus, alpha-TC glucagonoma cells contain ATP-sensitive K+ channels that regulate glucagon release, yet allow inhibition of hormone release by glucose."1.29Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. ( Buettger, C; Epstein, AJ; Hang, TL; Matschinsky, FM; Ronner, P, 1993)
"All of the clinical manifestations of glucagonoma syndrome so far reported in the literature were noted but there was no evidence indicating the presence of multiple endocrine adenomatosis."1.26A case with glucagonoma syndrome--endocrine and metabolic studies. ( Fukushima, H; Kitoh, M; Konno, T; Takemiya, M; Uzawa, H; Yamaguchi, K, 1981)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hendriks, T1
Jansen, JB1
van Tongeren, JH1
Fukushima, H1
Yamaguchi, K1
Uzawa, H1
Kitoh, M1
Takemiya, M1
Konno, T1
Ronner, P1
Matschinsky, FM1
Hang, TL1
Epstein, AJ1
Buettger, C1
Thompson, CS1
O'Dorisio, TM1
Woltering, EA1

Trials

1 trial available for tolbutamide and Adenoma, alpha-Cell

ArticleYear
Calcium reverses octreotide inhibition of insulin and glucagon levels in patients with insulinoma and glucagonoma.
    Digestion, 1996, Volume: 57 Suppl 1

    Topics: Antineoplastic Agents, Hormonal; Calcium; Glucagon; Glucagonoma; Humans; Hypoglycemic Agents; Infusi

1996

Other Studies

3 other studies available for tolbutamide and Adenoma, alpha-Cell

ArticleYear
The glucagonoma syndrome: stimulus-induced plasma responses of circulating glucagon components IRG9000 and IRG3500.
    Acta endocrinologica, 1984, Volume: 105, Issue:2

    Topics: Adenoma, Islet Cell; Arginine; Calcitonin; Calcium; Chromatography, Gel; Fasting; Female; Glucagon;

1984
A case with glucagonoma syndrome--endocrine and metabolic studies.
    Endocrinologia japonica, 1981, Volume: 28, Issue:2

    Topics: Adenoma, Islet Cell; C-Peptide; Endocrine Glands; Female; Glucagon; Glucagonoma; Glucose Tolerance T

1981
Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells.
    Diabetes, 1993, Volume: 42, Issue:12

    Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Diazoxide; Glucagon; Glucagono

1993