tolbutamide has been researched along with Acromegaly in 27 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Acromegaly: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In five patients with islet cell tumors and fasting hypoglycemia, basal proinsulin-like component ranged from 26 to 79% of the total immunoreactive insulin." | 1.25 | Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors. ( Gorden, P; Roth, J; Sherman, B, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BERGENSTAL, DM | 1 |
| LUBS, HA | 1 |
| HALLMAN, LF | 1 |
| SCHRICKER, JA | 1 |
| BRUNET, J | 1 |
| NADEAU, G | 1 |
| MOISAN, A | 1 |
| SAUCIER, G | 1 |
| BABA, S | 1 |
| MATSUOKA, A | 1 |
| TAKAISHI, T | 1 |
| Cerasi, E | 2 |
| Luft, R | 1 |
| Pelkonen, R | 1 |
| Taskinen, MR | 1 |
| Nikkilä, EA | 1 |
| Farag, Y | 1 |
| Gaafar, MA | 1 |
| Searle, GL | 1 |
| Adamson, U | 1 |
| Borisova, AM | 1 |
| Ovcharova, N | 1 |
| Kirilov, G | 1 |
| Gropp, C | 1 |
| Moses, AM | 1 |
| Miller, M | 1 |
| Ewer, RW | 1 |
| Deiss, WP | 1 |
| Gorden, P | 2 |
| Roth, J | 3 |
| Sherman, B | 1 |
| Kato, Y | 1 |
| Serrano-Rios, M | 3 |
| Ramos, F | 3 |
| Vivanco, F | 3 |
| Rodriguez-Minon, JL | 2 |
| Taylor, AL | 1 |
| Finster, JL | 1 |
| Raskin, P | 1 |
| Field, JB | 1 |
| Mintz, DH | 1 |
| Crepaldi, G | 1 |
| Tiengo, A | 1 |
| Muggeo, M | 1 |
| Trisotto, A | 1 |
| Federspil, G | 1 |
| Scandellari, C | 1 |
| Glick, SM | 1 |
| Cuatrecasas, P | 1 |
| Hollander, CS | 1 |
| Rodriguez Miñón, JL | 1 |
| Yoshida, T | 1 |
| Boden, G | 1 |
| Soeldner, JS | 1 |
| Beck, P | 1 |
| Schalch, DS | 1 |
| Parker, ML | 1 |
| Kipnis, DM | 2 |
| Daughaday, WH | 1 |
| Massara, F | 1 |
| Camanni, F | 1 |
| Molinatti, GM | 1 |
| Lazarus, L | 1 |
| Young, JD | 1 |
| Perley, M | 1 |
2 reviews available for tolbutamide and Acromegaly
| Article | Year |
|---|---|
[RECENT INFORMATION ON THE ETIOLOGY OF DIABETES MELLITUS AND A STUDY OF IT].
Topics: Acromegaly; Adrenocorticotropic Hormone; Diabetes Mellitus; Endocrine Glands; Exophthalmos; Growth H | 1964 |
The use of isotope turnover techniques in the study of carbohydrate metabolism in man.
Topics: Acromegaly; Alanine; Blood Glucose; Carbohydrate Metabolism; Carbon Dioxide; Carbon Isotopes; Ethano | 1976 |
25 other studies available for tolbutamide and Acromegaly
| Article | Year |
|---|---|
Effects of tolbutamide on the diabetes of acromegaly and on the blood sugar in patients with altered endocrine states.
Topics: Acromegaly; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Endocrine System Diseases; Hem | 1957 |
[EXPERIMENTAL STUDY OF THE INDUCED HYPERGLYCEMIA TEST INDUCED BY VENOUS ROUTE].
Topics: Acromegaly; Androgens; Cortisone; Diabetes Mellitus; Female; Glucose Tolerance Test; Glycosuria; Hyp | 1964 |
"What is inherited--what is added" hypothesis for the pathogenesis of diabetes mellitus.
Topics: Acromegaly; Adult; Carbon Isotopes; Computers, Analog; Diabetes Mellitus; Female; Glucose; Glucose T | 1967 |
Response of plasma insulin to small doses of tolbutamide in obesity and acromegaly.
Topics: Acromegaly; Blood Glucose; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Insulin; | 1977 |
Insulin tolerance test and tolbutamide tolerance test in acromegaly.
Topics: Acromegaly; Adult; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Male; Middle Aged; To | 1977 |
Acute suppressive effect of human growth hormone on insulin release induced by glucagon and tolbutamide in man.
Topics: Acromegaly; Adult; Blood Glucose; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; Growt | 1975 |
[Insulin secretion and action in acromegaly].
Topics: Acromegaly; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Gro | 1987 |
[Staining and immunohistological differentiation of acidophilic cells of the pituitary gland anterior lobe].
Topics: Acromegaly; Adult; Animals; Cats; Cattle; Dogs; Female; Fetus; Fluorescent Antibody Technique; Human | 1971 |
Stimulation and inhibition of ACTH release in patients with pituitary disease.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adrenocorticotropic Hormone; Adult; Aged; Dexamethasone; Diab | 1968 |
Clinical experience with human growth hormone immunoassay by a two-antibody method.
Topics: Acromegaly; Adenoma, Chromophobe; Adenoma, Islet Cell; Amenorrhea; Anorexia Nervosa; Arginine; Dwarf | 1969 |
Plasma insulin: fluctuations in the "big" insulin component in man after glucose and other stimuli.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Arginine; Fasting; Female; Glucose; Glucose Tole | 1969 |
Proinsulin-like component of circulating insulin in the basal state and in patients and hamsters with islet cell tumors.
Topics: Acromegaly; Adenoma, Islet Cell; Adolescent; Adult; Animals; Child; Chromatography, Gel; Cricetinae; | 1971 |
[Secretion of human growth hormone (HGH). 1. Basic study of HGH determination and serum HGH in normal subjects].
Topics: Acromegaly; Adult; Animals; Antibodies; Arginine; Blood Glucose; Female; Glucose Tolerance Test; Gro | 1972 |
[Secretion of insulin during the first phases of diabetes. Summary of the experiments of the authors].
Topics: Acromegaly; Adolescent; Adult; Body Weight; Diabetes Mellitus; Female; Glucose Tolerance Test; Human | 1973 |
[Insulin secretion in the early stages of diabetes mellitus (author's transl)].
Topics: Acromegaly; Diabetes Mellitus; Glucose Tolerance Test; Humans; Insulin; Obesity; Prediabetic State; | 1973 |
Pituitary apoplexy in acromegaly.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adult; Arginine; Blood; Blood Glucose; Diabe | 1968 |
[Primary and secondary hyperinsulinism].
Topics: Acromegaly; Cushing Syndrome; Diabetes Complications; Glucagon; Glucose Tolerance Test; Humans; Hype | 1970 |
Acromegaly and other disorders of growth hormone secretion. Combined clinical staff conference at the National Institutes of Health.
Topics: Acromegaly; Adolescent; Adult; Aged; Blood Glucose; Child; Diabetes Mellitus; Diagnosis, Differentia | 1967 |
Glucose tolerance in acromegaly: a study of insulin secretion.
Topics: Acromegaly; Adult; Female; Glucose Tolerance Test; Growth Hormone; Humans; Hyperinsulinism; Insulin; | 1972 |
[Clinical studies on the immunoreactive insulin. II. The immunoreactive insulin (IRI) in normal subjects and patients with diabets mellitus and other endocrinopathy].
Topics: Acromegaly; Adolescent; Adult; Aged; Anemia, Aplastic; Arginine; Child; Child, Preschool; Circadian | 1970 |
A sensitive double antibody radioimmunoassay for human growth hormone (HGH): levels of serum HGH following rapid tolbutamide infusion.
Topics: Acromegaly; Animals; Anura; Cattle; Female; Growth Hormone; Guinea Pigs; Humans; Hypophysectomy; Ins | 1967 |
Correlative studies of growth hormone and insulin plasma concentrations with metabolic abnormalities in acromegaly.
Topics: Acromegaly; Blood; Blood Glucose; Fatty Acids; Glucose Tolerance Test; Growth Hormone; Humans; Hyper | 1965 |
[The tolbutamide test in acromegaly. Preliminary observations].
Topics: Acromegaly; Adult; Female; Glucose Tolerance Test; Humans; Male; Middle Aged; Tolbutamide | 1966 |
Radioimmunoassay of human growth hormone using ion exchange resin.
Topics: Acromegaly; Adolescent; Adult; Aged; Child; Child, Preschool; Cryosurgery; Growth Hormone; Humans; H | 1966 |
Effect of glucocorticoids on plasma insulin.
Topics: Acromegaly; Blood; Dexamethasone; Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Injections, Int | 1966 |