tolbutamide and Abnormalities, Multiple studies

tolbutamide and Abnormalities, Multiple

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Abnormalities, Multiple: Congenital abnormalities that affect more than one organ or body structure.

Research Excerpts

Excerpt	Relevance	Reference
"Cromakalim is a K(+) channel opener that causes smooth muscle relaxation by activating ATP-sensitive K(+) (K(ATP)) channels and producing membrane hyperpolarization."	1.30	Cromakalim: embryonic effects and reduction of tolbutamide-induced dysmorphogenesis in vitro. ( Smoak, IW, 1999)

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (60.00)	18.7374
1990's	2 (40.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

3 (60.00)

18.7374

1990's

2 (40.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Smoak, IW	1
Schabel, F	1
Frisch, H	1
Saili, A	1
Sarna, MS	1
Schiff, D	1
Colle, E	1
Wells, D	1
Stern, L	1
Cotton, RB	1
Keats, TE	1
McCoy, EE	1

Studies

Smoak, IW

Schabel, F

Frisch, H

Saili, A

Sarna, MS

Schiff, D

Colle, E

Wells, D

Stern, L

Cotton, RB

Keats, TE

McCoy, EE

Other Studies

5 other studies available for tolbutamide and Abnormalities, Multiple

Article	Year
Cromakalim: embryonic effects and reduction of tolbutamide-induced dysmorphogenesis in vitro. Teratology, 1999, Volume: 60, Issue:5 Topics: Abnormalities, Multiple; Animals; Cromakalim; Embryonic and Fetal Development; Female; Hypoglycemic	1999
[Exaggerated somatomedin activity in the Beckwith-Wiedemann syndrome (author's transl)]. Padiatrie und Padologie, 1979, Volume: 14, Issue:3 Topics: Abnormalities, Multiple; Gigantism; Glucose Tolerance Test; Hernia, Umbilical; Humans; Hypoglycemia;	1979
Tolbutamide: teratogenic effects. Indian pediatrics, 1991, Volume: 28, Issue:8 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Arm; Female; Humans; Infant, Newborn; Leg; Mal	1991
Metabolic aspects of the Beckwith-Wiedemann syndrome. The Journal of pediatrics, 1973, Volume: 82, Issue:2 Topics: Abnormalities, Multiple; Adrenal Gland Diseases; Blood Glucose; Child, Preschool; Diazoxide; Epineph	1973
Abnormal blood glucose regulation in Cockayne's syndrome. Pediatrics, 1970, Volume: 46, Issue:1 Topics: Abnormalities, Multiple; Adolescent; Black or African American; Blood Glucose; Chromosomes, Human, 6	1970

Article

Year

Cromakalim: embryonic effects and reduction of tolbutamide-induced dysmorphogenesis in vitro.

Teratology, 1999, Volume: 60, Issue:5

Topics: Abnormalities, Multiple; Animals; Cromakalim; Embryonic and Fetal Development; Female; Hypoglycemic

1999

[Exaggerated somatomedin activity in the Beckwith-Wiedemann syndrome (author's transl)].

Padiatrie und Padologie, 1979, Volume: 14, Issue:3

Topics: Abnormalities, Multiple; Gigantism; Glucose Tolerance Test; Hernia, Umbilical; Humans; Hypoglycemia;

1979

Tolbutamide: teratogenic effects.

Indian pediatrics, 1991, Volume: 28, Issue:8

Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Arm; Female; Humans; Infant, Newborn; Leg; Mal

1991

Metabolic aspects of the Beckwith-Wiedemann syndrome.

The Journal of pediatrics, 1973, Volume: 82, Issue:2

Topics: Abnormalities, Multiple; Adrenal Gland Diseases; Blood Glucose; Child, Preschool; Diazoxide; Epineph

1973

Abnormal blood glucose regulation in Cockayne's syndrome.

Pediatrics, 1970, Volume: 46, Issue:1

Topics: Abnormalities, Multiple; Adolescent; Black or African American; Blood Glucose; Chromosomes, Human, 6

1970