tolazoline has been researched along with Muscle Contraction in 51 studies
Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of metoclopramide on smooth muscle contraction and on release of acetylcholine were studied in the guinea-pig myenteric plexus longitudinal muscle preparation." | 3.66 | The effects of metoclopramide on acetylcholine release and on smooth muscle response in the isolated guinea-pig ileum. ( Kilbinger, H; Kruel, R; Pfeuffer-Friederich, I; Wessler, I, 1982) |
| "Both tolazoline and clonidine produce agonist effects sensitive to histamine H2-receptor antagonism in whole animals and a variety of isolated tissues." | 1.26 | The histamine-like effects of tolazoline and clonidine:: evidence against direct activity at histamine receptors. ( Angus, JA; Kenakin, TP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (88.24) | 18.7374 |
| 1990's | 5 (9.80) | 18.2507 |
| 2000's | 1 (1.96) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| VANALPHEN, GW | 1 |
| KERN, R | 1 |
| ROBINETTE, SL | 1 |
| Fatehi-Hassanabad, Z | 1 |
| Fatehi, M | 1 |
| Badia, A | 1 |
| Bermejo, P | 1 |
| Jané, F | 1 |
| Greenberg, S | 2 |
| Kadowitz, PJ | 1 |
| Hyman, A | 1 |
| Curron, FA | 1 |
| Drummond, WH | 1 |
| Curro, FA | 1 |
| Kilbinger, H | 1 |
| Kruel, R | 1 |
| Pfeuffer-Friederich, I | 1 |
| Wessler, I | 1 |
| Kenakin, TP | 1 |
| Angus, JA | 1 |
| Manning, MM | 1 |
| Broadstone, RV | 1 |
| Lei, L | 2 |
| Slavica, M | 2 |
| Ernsberger, P | 1 |
| Graves, ME | 1 |
| Patil, P | 1 |
| Miller, D | 1 |
| Feller, D | 1 |
| Patil, PN | 3 |
| Kerezy, A | 1 |
| Feller, DR | 1 |
| Miller, DD | 3 |
| Jing, L | 1 |
| Jagadeesh, JM | 1 |
| De Los Angeles, J | 1 |
| Arbilla, S | 1 |
| Langer, SZ | 2 |
| Andersson, RG | 1 |
| Lindgren, BR | 1 |
| Colldahl, H | 1 |
| Holsapple, MP | 1 |
| Blake, DE | 1 |
| Yim, GK | 1 |
| Gintzler, AR | 1 |
| Musacchio, JM | 1 |
| Nakanishi, H | 3 |
| Yoshida, H | 1 |
| Suzuki, T | 2 |
| Nakahata, N | 1 |
| Sanders, J | 1 |
| Wikberg, J | 1 |
| Yanaura, S | 1 |
| Ishikawa, S | 1 |
| Staneva-Stoytcheva, D | 1 |
| Tchakarova, L | 1 |
| Kuchev, V | 1 |
| Yu, DY | 1 |
| Alder, VA | 1 |
| Su, EN | 1 |
| Cringle, SJ | 1 |
| Wick, PF | 1 |
| Keung, AC | 1 |
| Bowler, JJ | 1 |
| Deth, RC | 1 |
| Ruckebusch, Y | 1 |
| Allal, C | 1 |
| Satchell, D | 1 |
| Burnstock, G | 1 |
| Dann, P | 1 |
| MacLeod, DP | 1 |
| Hunter, EG | 1 |
| McNeill, JH | 1 |
| Davis, RS | 1 |
| Muschek, LD | 1 |
| Takeda, H | 1 |
| Dzoljić, M | 1 |
| Takagi, K | 3 |
| Osada, E | 1 |
| Takayanagi, I | 3 |
| Taga, F | 2 |
| Ward, CO | 1 |
| Gautieri, RF | 2 |
| Coupar, IM | 1 |
| Kirby, MJ | 1 |
| Takeshi, O | 1 |
| Tamayo, L | 1 |
| Contreras, E | 1 |
| Quijada, L | 1 |
| O'Shea, JD | 1 |
| Phillips, RE | 1 |
| Toda, N | 2 |
| Usui, H | 2 |
| Mori, J | 1 |
| Nishino, N | 1 |
| Fujiwara, M | 1 |
| Sherman, WT | 1 |
| Lund, GF | 1 |
| Christensen, J | 2 |
| Chopra, YM | 1 |
| Dandiya, PC | 1 |
| Weisbrodt, NW | 3 |
| Hug, CC | 4 |
| Bass, P | 4 |
| Carlson, GM | 1 |
| Ruddon, RW | 1 |
| Schmiege, SK | 1 |
| Butterworth, KR | 1 |
| Randall, MJ | 1 |
| Weisenthal, LM | 1 |
| Daniel, EE | 1 |
| Hoszowska-Owczarek, A | 1 |
| Djordjevic, N | 1 |
| De Schaepdryver, AF | 1 |
| Vohra, MM | 1 |
1 review available for tolazoline and Muscle Contraction
| Article | Year |
|---|---|
Persistent pulmonary hypertension of the neonate (persistent fetal circulation syndrome).
Topics: Acetylcholine; Calcium; Catecholamines; Epoprostenol; Homeostasis; Humans; Hypertension, Pulmonary; | 1983 |
50 other studies available for tolazoline and Muscle Contraction
| Article | Year |
|---|---|
ADRENERGIC RECEPTORS OF THE INTRAOCULAR MUSCLES: COMPARISON TO CAT, RABBIT, AND MONKEY.
Topics: Animals; Cats; Epinephrine; Haplorhini; Histology, Comparative; Isoproterenol; Muscle Contraction; N | 1965 |
Characterisation of some pharmacological effects of the venom from Vipera lebetina.
Topics: Analysis of Variance; Animals; Blood Pressure; Guinea Pigs; Heart Atria; Ileum; Iran; Male; Muscle C | 2004 |
Pre- and postsynaptic effects of sulpiride in the rat isolated vas deferens.
Topics: Animals; Apomorphine; Dopamine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; | 1982 |
Adrenergic mechanisms in canine intralobar pulmonary arteries and veins.
Topics: Animals; Bretylium Compounds; Clonidine; Cocaine; Dogs; Dose-Response Relationship, Drug; Electric S | 1981 |
Differential inhibition of 5-hydroxytryptamine (5-HT) mediated contraction of rat thoracic aortae by phentolamine and tolazoline: correlation with inhibition of 5-HT binding and calcium ion.
Topics: Animals; Aorta, Thoracic; Calcium; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrin | 1983 |
The effects of metoclopramide on acetylcholine release and on smooth muscle response in the isolated guinea-pig ileum.
Topics: Acetylcholine; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Metoclopramid | 1982 |
The histamine-like effects of tolazoline and clonidine:: evidence against direct activity at histamine receptors.
Topics: Animals; Clonidine; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Male; Muscle Contractio | 1981 |
Effects of alpha 2-adrenergic receptor agonist and antagonist drugs on cholinergic contraction in bovine tracheal smooth muscle in vitro.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrene | 1995 |
Calcium channel-dependent and I1-imidazoline receptor binding properties of 2-(4'-isothiocyanatobenzyl) imidazoline analogs in vascular and brain tissues.
Topics: Aorta; Calcium Channels; Imidazoline Receptors; In Vitro Techniques; Ion Channel Gating; Medulla Obl | 1995 |
Synthesis and biological activities of a new set of irreversibly acting 2-(4'-isothiocyanatobenzyl)imidazoline analogs in rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Calcium Channels; Dioxanes; Idazoxan; Imidazoles; In Vitro Techniques; Mal | 1994 |
Depolarization of membrane potential and the smooth muscle contraction by isothiocyanatobenzyl imidazoline in guinea-pig stomach circular muscle.
Topics: Animals; Atropine; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Te | 1999 |
Differences between presynaptic and postsynaptic alpha-adrenoceptors in the isolated nictitating membrane of the cat: effects of metanephrine and tolazoline.
Topics: Animals; Cats; Electric Stimulation; Epinephrine; Female; In Vitro Techniques; Male; Metanephrine; M | 1978 |
Inhibitory effects of imidazolines on histamine liberation from human leukocytes and on tracheal smooth muscle tone.
Topics: Animals; Cattle; Cimetidine; Clemastine; Clonidine; Guinea Pigs; Histamine H1 Antagonists; Histamine | 1978 |
Reversible depression of electrically-induced contractions of guinea pig longitudinal muscle by a reversible inhibitor of prostaglandin synthetase.
Topics: Amidines; Animals; Chlorphenamidine; Clonidine; Cyclooxygenase Inhibitors; Guinea Pigs; Indomethacin | 1979 |
Interactions of morphine, adenosine, adenosine triphosphate and phosphodiesterase inhibitors on the field-stimulated guinea-pig ileum.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; Guinea Pigs; Il | 1975 |
Inhibitory effects of prostaglandin E1 and E2 on cholinergic transmission in isolated canine tracheal muscle.
Topics: Acetylcholine; Animals; Atropine; Dogs; Drug Interactions; Electric Stimulation; Female; In Vitro Te | 1976 |
Depressive effect of epinephrine mediated via adrenergic beta-receptor in isolated rat colon and duodenum.
Topics: Acetylcholine; Animals; Bucladesine; Colon; Depression, Chemical; Duodenum; Epinephrine; In Vitro Te | 1977 |
Alpha adrenergic and histaminergic effects of tolazoline-like imidazolines.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Chlorpheniramine; Guinea Pigs; Heart Atria; His | 1975 |
Differentiation between pre- and postjunctional alpha-receptors in guinea pig ileum and rabbit aorta.
Topics: Animals; Aorta, Thoracic; Cimetidine; Clonidine; Dibenzylchlorethamine; Dose-Response Relationship, | 1978 |
[Adrenoceptors and autonomic nerve control mechanisms in the biliary tract].
Topics: Animals; Atropine; Biliary Tract; Common Bile Duct; Dibenzylchlorethamine; Dose-Response Relationshi | 1975 |
Response to noradrenaline and 14C-noradrenaline uptake of vascular strips in experimental atherosclerosis.
Topics: Animals; Aorta; Arteriosclerosis; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Cont | 1975 |
Relaxation effects of diltiazem, verapamil, and tolazoline on isolated cat ophthalmociliary artery.
Topics: Animals; Cats; Diltiazem; Dose-Response Relationship, Drug; Muscle Contraction; Muscle Relaxation; M | 1992 |
Alpha-1 adrenergic coupling events induced by full and partial agonists in rabbit aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; Dose-Response Rela | 1987 |
Depression of reticulo-ruminal motor functions through the stimulation of alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Cattle; Clonidine; Female; Imidazoles; Muscle Contraction; Retic | 1987 |
Antagonism of the effects of purinergic nerve stimulation and exogenously applied ATP on the guinea-pig taenia coli by 2-substituted imidazolines and related compounds.
Topics: Adenosine Triphosphate; Amyl Nitrite; Aniline Compounds; Animals; Benzyl Compounds; Colon; Electric | 1973 |
The pharmacology of the cardiac muscle of the great veins of the rat.
Topics: Acetylcholine; Action Potentials; Angiotensin II; Animals; Atrial Function; Atropine; Carbachol; Ele | 1967 |
Phenylephrine effects on cardiac contractility adenyl cyclase, and phosphorylase.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Drug Antagonism; Epinephrine; Female; Fluorides; Glucosyltra | 1972 |
The possibility that adenosine triphosphate is an excitatory transmitter in guinea-pig seminal vesicle.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Hypogastric Plexus; In Vitro Tec | 1972 |
Stimulatory effect of tolazoline on smooth muscle.
Topics: Acetylcholine; Anesthetics, Local; Animals; Atropine; Drug Synergism; Electric Stimulation; Ganglion | 1967 |
Adrenergic receptors on some organs.
Topics: Animals; Aorta; Blood Pressure; Cats; Epinephrine; Ethanolamines; Female; Guinea Pigs; Ileum; In Vit | 1967 |
Effect of certain drugs on perfused human placenta. IX. Mode of action of angiotensin.
Topics: Angiotensin II; Blood Vessels; Constriction; Dipyridamole; Ethanolamines; Female; Humans; Hydralazin | 1969 |
The effect of clonidine on human isolated smooth muscle.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Colon; Drug Antagon | 1972 |
Interrelation between the alpha- and beta-receptor activating actions of catecholamines in the tracheal muscle.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Catecholamines; Dibenzylchlorethamine; Epinephrine; | 1969 |
Supersensitivity to alpha and beta effects of adrenaline induced by cocaine.
Topics: Animals; Cocaine; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Drug Interactions; Epinep | 1974 |
Contractility in vitro of ovarian follicles from sheep, and the effects of drugs.
Topics: Acetylcholine; Animals; Carbachol; Corpus Luteum; Epinephrine; Estrus; Female; Histamine; In Vitro T | 1974 |
Contractile responses of spiral strips of large blood vessels from rabbits to transmural stimulation and tyramine.
Topics: Animals; Aorta; Arteries; Bretylium Compounds; Dopamine; Electric Stimulation; Female; Male; Mesente | 1972 |
Cardiovascular effects of capsaicin in dogs and rabbits.
Topics: Alkaloids; Amides; Animals; Aorta; Arteries; Atropine; Blood Pressure; Calcium; Capsicum; Depression | 1972 |
Effect of certain drugs on perfused human placenta. X. Norepinephrine release by bradykinin.
Topics: Atropine; Bradykinin; Diphenhydramine; Drug Interactions; Female; Fluorescence; Humans; Muscle Contr | 1972 |
Electrical stimulation of esophageal smooth muscle and effects of antagonists.
Topics: Acetylcholine; Animals; Atropine; Autonomic Nervous System; Electric Stimulation; Esophagus; Hexamet | 1969 |
On the mechanism of reversal of reserpine action by pargyline hydrochloride.
Topics: Animals; Atropine; Blood Pressure; Cyproheptadine; Dogs; Epinephrine; Female; Heart Rate; Male; Meth | 1969 |
Separation of the effects of alpha and beta adrenergic receptor stimulation on taenia coli.
Topics: Aminophylline; Animals; Catecholamines; Cell Membrane; Epinephrine; Guinea Pigs; Isoproterenol; Male | 1969 |
Effects of nicotine on gastric antral and duodenal contractile activity in the dog.
Topics: Anilides; Animals; Carbamates; Dogs; Duodenum; Epinephrine; Ergotamine; Gastrointestinal Motility; M | 1970 |
Partial agonists and acetylcholine liberation.
Topics: Acetylcholine; Animals; Atropine; Cocaine; Cold Temperature; Dibenzylchlorethamine; Guinea Pigs; Hex | 1970 |
Effects of nicotine and tyramine on contractile activity of the colon.
Topics: Adrenal Glands; Adrenalectomy; Animals; Catecholamines; Cocaine; Colon; Dogs; Female; Gastrointestin | 1970 |
The effects of alpha- and beta-adrenoceptor blocking agents on the responses of the rat uterus to catecholamines throughout the oestrus cycle.
Topics: Animals; Catecholamines; Epinephrine; Estrus; Female; Isoproterenol; Muscle Contraction; Norepinephr | 1970 |
Adrenergic mechanisms in the relaxation of guinea-pig taenia coli in vitro.
Topics: Animals; Catecholamines; Colon; Electric Stimulation; Female; Guanethidine; Guinea Pigs; Hexamethoni | 1971 |
Effects of some autonomic drugs on circular esophageal smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Autonomic Agents; Carbachol; Cats; Electrophysiology; Epinephrine; | 1968 |
Electrophysiological experiments on the action of some partial agonists and their application to receptor theory.
Topics: Acetylcholine; Animals; Atropine; Cecum; Choline; Dibenzylchlorethamine; Diphenhydramine; Electrophy | 1968 |
Stimulant action of tolazoline on the nictitating membrane of the pithed cat.
Topics: Animals; Cats; Cocaine; Drug Antagonism; Female; Male; Muscle Contraction; Nictitating Membrane; Nor | 1968 |
The responses of rat and guinea pig vas deferens to cocaine.
Topics: Acetylcholine; Animals; Atropine; Cocaine; Guinea Pigs; Male; Muscle Contraction; Norepinephrine; Ph | 1969 |