tolazoline has been researched along with Hypotension in 15 studies
Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combined application of Tolazoline and Dopamine for the treatment of the persistent fetal circulation syndrome showed that Dopamine prevented the most common side effects of Tolazoline i." | 7.66 | [Tolazoline and dopamine in the treatment of the persistent fetal circulation syndrome]. ( Csömör, S; Kiszel, J; Machay, T; Seri, I; Téglás, E; Tulassay, TL, 1983) |
| "Clonidine poisoning usually causes depressed sensorium, hypotension, and bradycardia." | 4.76 | Clonidine overdose: report of six cases and review of the literature. ( Anderson, RJ; Crumpler, CP; Hart, GR; Lerman, MJ, 1981) |
| " Reversal of xylazine-induced sedation with tolazoline caused transient sinus bradycardia and sinus arrest, accompanied by severe systemic arterial hypotension." | 3.70 | Sedation with xylazine and lumbosacral epidural administration of lidocaine and xylazine for umbilical surgery in calves. ( Constable, PD; Huhn, JC; Lewis, CA; Morin, DE, 1999) |
| "The combined application of Tolazoline and Dopamine for the treatment of the persistent fetal circulation syndrome showed that Dopamine prevented the most common side effects of Tolazoline i." | 3.66 | [Tolazoline and dopamine in the treatment of the persistent fetal circulation syndrome]. ( Csömör, S; Kiszel, J; Machay, T; Seri, I; Téglás, E; Tulassay, TL, 1983) |
| " Ventilatory support must be available if apnea occurs." | 3.66 | Clonidine poisoning. A complex problem. ( Artman, M; Boerth, RC, 1983) |
| " Some infants with severe, persistent pulmonary hypertension who were receiving an intravascular infusion of tolazoline and infants with mean arterial blood pressures more than 2." | 3.66 | Transcutaneous oxygen tension in sick infants. ( Gregory, GA; Peabody, JL; Tooley, WH; Willis, MM, 1978) |
| "We randomly assigned 24 neonates with hypoxemia to receive tolazoline hydrochloride." | 2.66 | Bolus and continuous infusion of tolazoline in neonates with hypoxemia. ( McMillan, DD; Sauve, RS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KOKHNACHEVA, AI | 1 |
| SAMOILOVA, ZT | 1 |
| Seri, I | 2 |
| Tulassay, T | 1 |
| Kiszel, J | 2 |
| Machay, T | 2 |
| Lipták, M | 1 |
| Csömör, S | 2 |
| Tulassay, TL | 1 |
| Téglás, E | 1 |
| Artman, M | 1 |
| Boerth, RC | 1 |
| Anderson, RJ | 1 |
| Hart, GR | 1 |
| Crumpler, CP | 1 |
| Lerman, MJ | 1 |
| Lewis, CA | 1 |
| Constable, PD | 1 |
| Huhn, JC | 1 |
| Morin, DE | 1 |
| Menzel, K | 1 |
| Schambach, K | 1 |
| Töpke, B | 1 |
| Carlon, GC | 1 |
| Peabody, JL | 1 |
| Gregory, GA | 1 |
| Willis, MM | 1 |
| Tooley, WH | 1 |
| Mendoza, JE | 1 |
| Medalie, M | 1 |
| Poyner, TF | 1 |
| Gennery, BA | 1 |
| Vasey, RH | 1 |
| Nolan, AM | 1 |
| Erhardt, W | 1 |
| Balsan, MJ | 1 |
| Cronin, CM | 1 |
| Shaw, MD | 1 |
| Milley, JR | 1 |
| McMillan, DD | 1 |
| Sauve, RS | 1 |
| Stern, L | 1 |
3 reviews available for tolazoline and Hypotension
| Article | Year |
|---|---|
Clonidine overdose: report of six cases and review of the literature.
Topics: Adolescent; Adult; Atropine; Bradycardia; Child, Preschool; Clonidine; Dopamine; Female; Humans; Hyp | 1981 |
[The patent ductus arteriosus from a perinatological viewpoint].
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Fetus; Gastrointestinal Hemorrhage; Growth; Hu | 1978 |
Therapy of the respiratory distress syndrome.
Topics: Body Temperature Regulation; Catecholamines; Fibrinolytic Agents; Histamine H1 Antagonists; Homeosta | 1972 |
2 trials available for tolazoline and Hypotension
| Article | Year |
|---|---|
[Tolazoline and dopamine in the management of persistent fetal circulation].
Topics: Blood Circulation; Clinical Trials as Topic; Dopamine; Drug Interactions; Drug Therapy, Combination; | 1984 |
Bolus and continuous infusion of tolazoline in neonates with hypoxemia.
Topics: Female; Gastrointestinal Hemorrhage; Humans; Hypotension; Hypoxia; Infant, Newborn; Infusions, Paren | 1986 |
10 other studies available for tolazoline and Hypotension
| Article | Year |
|---|---|
[Hypotensive effects of priscol].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypotension; Tolazoline | 1950 |
[Tolazoline and dopamine in the treatment of the persistent fetal circulation syndrome].
Topics: Dopamine; Drug Therapy, Combination; Female; Humans; Hypotension; Infant, Newborn; Male; Oliguria; P | 1983 |
Clonidine poisoning. A complex problem.
Topics: Apnea; Bradycardia; Child, Preschool; Clonidine; Dopamine; Female; Fluid Therapy; Gastric Lavage; Hu | 1983 |
Sedation with xylazine and lumbosacral epidural administration of lidocaine and xylazine for umbilical surgery in calves.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia, Epidural; Anesthetics, Local; An | 1999 |
Fatal association of tolazoline and dopamine.
Topics: Adenocarcinoma; Adult; Anuria; Dopamine; Drug Synergism; Esophageal Neoplasms; Humans; Hypotension; | 1979 |
Transcutaneous oxygen tension in sick infants.
Topics: Blood Pressure; Electrodes; Evaluation Studies as Topic; Heart Defects, Congenital; Heart Rate; Huma | 1978 |
Clonidine poisoning with marked hypotension in a 2 1/2-year-old child.
Topics: Child, Preschool; Clonidine; Female; Humans; Hypotension; Tolazoline | 1979 |
Management in cases of clonidine overdosage.
Topics: Adolescent; Atropine; Blood Pressure; Bradycardia; Clonidine; Diuresis; Female; Humans; Hypotension; | 1976 |
The cardiorespiratory effects of intrathecal xylazine in the conscious rabbit.
Topics: Animals; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Cardiac Output; Hypotension; Injectio | 1990 |
Blood flow distribution and brain metabolism during tolazoline-induced hypotension in newborn dogs.
Topics: Animals; Animals, Newborn; Brain; Cerebrovascular Circulation; Dogs; Hemodynamics; Hypotension; Hypo | 1990 |