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tolazoline and Hypertension, Pulmonary

tolazoline has been researched along with Hypertension, Pulmonary in 73 studies

Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
"The condition of a neonate with severe persistent pulmonary hypertension who became severely hypoxic and acidotic despite intensive conventional treatment improved dramatically after endotracheal administration of tolazoline."7.69Endotracheal tolazoline for severe persistent pulmonary hypertension of the newborn. ( Bridson, JM; Gibbs, JL; Welch, JC, 1995)
"After antenatal induction of diaphragmatic hernias in fetal lambs, prostaglandins D2, E1, and I2 were compared to tolazoline, or isoprenaline, for the treatment of pulmonary hypertension."7.68Pulmonary hypertension in lambs with congenital diaphragmatic hernia: vasodilator prostaglandins, isoprenaline, and tolazoline. ( Barker, AP; Ford, WD; Lee, CM; Sen, S, 1990)
"Tolazoline Hydrochloride is a pulmonary vasodilator that is used for the treatment of pulmonary hypertension of the newborn."7.67Duodenal ulceration: a complication of tolazoline therapy. ( Auldist, A; Butt, W; Duncan, A; McDougall, P, 1986)
"We studied the separate and combined effects of hyperventilation and administration of dopamine and tolazoline in five infants with pulmonary hypertension managed with indwelling pulmonary artery catheters."7.66The independent effects of hyperventilation, tolazoline, and dopamine on infants with persistent pulmonary hypertension. ( Drummond, WH; Gregory, GA; Heymann, MA; Phibbs, RA, 1981)
"If tolazoline treatment did not fulfill the criteria for pulmonary vasodilation, prostacyclin was given by continuous iv infusion at a starting rate of 5 ng/kg/min, followed by 10 ng/kg/min."5.28Effects of tolazoline and prostacyclin on pulmonary hypertension in infants after cardiac surgery. ( Huth, R; Iversen, S; Jüngst, BK; Oelert, H; Schranz, D; Wippermann, C; Zepp, F; Zimmer, B, 1992)
"Tolazoline treatment of neonates has been reported since 1965."5.27Oliguria and tolazoline pharmacokinetics in the newborn. ( Daniel, CH; Kendig, JW; Ward, RM; Wood, MA, 1986)
"The haemodynamic effects of infusion of epoprostenol (prostacyclin) and bolus injection of tolazoline were compared in a crossover study in 11 children with pulmonary hypertension caused by pulmonary vascular disease."5.06Comparison of the haemodynamic effects of epoprostenol (prostacyclin) and tolazoline. ( Bush, A; Busst, CM; Knight, WB; Shinebourne, EA, 1988)
"We describe a premature baby with X pentasomy, having a severe pulmonary hypertension secondary to perinatal asphyxia and hyaline membrane disease which appeared to be refractory to conventional treatments (hyperventilation, tolazoline, prostacyclin)."3.69[Efficacy of magnesium in a case of neonatal pulmonary hypertension refractory to the usual therapies]. ( Benettoni, A; Ciana, G; Colonna, F; Giorgi, R, 1994)
"The condition of a neonate with severe persistent pulmonary hypertension who became severely hypoxic and acidotic despite intensive conventional treatment improved dramatically after endotracheal administration of tolazoline."3.69Endotracheal tolazoline for severe persistent pulmonary hypertension of the newborn. ( Bridson, JM; Gibbs, JL; Welch, JC, 1995)
"The hemodynamic effects of acute oral administration of a newly-developed prostacyclin analogue (beraprost sodium; 1-2 micrograms/kg), inhaled nitric oxide (NO; 20 ppm) and tolazoline hydrochloride (1 mg/kg) were measured in 17 children (mean age 1 year and 9 months) with pulmonary hypertension complicating congenital heart disease or primary pulmonary hypertension."3.69Acute effect of oral prostacyclin and inhaled nitric oxide on pulmonary hypertension in children. ( Fukahara, K; Hamamichi, Y; Hashimoto, I; Ichida, F; Miyawaki, T; Murakami, A; Tsubata, S; Uese, K, 1997)
"A newborn was treated with tolazoline for persistent pulmonary hypertension."3.68[Interaction of tolazoline and cimetidine in persistent fetal circulation of the newborn infant]. ( Hanssler, L; Roll, C, 1993)
"After antenatal induction of diaphragmatic hernias in fetal lambs, prostaglandins D2, E1, and I2 were compared to tolazoline, or isoprenaline, for the treatment of pulmonary hypertension."3.68Pulmonary hypertension in lambs with congenital diaphragmatic hernia: vasodilator prostaglandins, isoprenaline, and tolazoline. ( Barker, AP; Ford, WD; Lee, CM; Sen, S, 1990)
"Tolazoline Hydrochloride is a pulmonary vasodilator that is used for the treatment of pulmonary hypertension of the newborn."3.67Duodenal ulceration: a complication of tolazoline therapy. ( Auldist, A; Butt, W; Duncan, A; McDougall, P, 1986)
"A neonate, managed with tolazoline for pulmonary hypertension after repair of a congenital diaphragmatic hernia, developed a duodenal perforation."3.67Duodenal perforation associated with tolazoline. ( George, RJ; McCormick, WJ; Raine, PA; Wilson, RG, 1985)
"We studied the separate and combined effects of hyperventilation and administration of dopamine and tolazoline in five infants with pulmonary hypertension managed with indwelling pulmonary artery catheters."3.66The independent effects of hyperventilation, tolazoline, and dopamine on infants with persistent pulmonary hypertension. ( Drummond, WH; Gregory, GA; Heymann, MA; Phibbs, RA, 1981)
" Some infants with severe, persistent pulmonary hypertension who were receiving an intravascular infusion of tolazoline and infants with mean arterial blood pressures more than 2."3.66Transcutaneous oxygen tension in sick infants. ( Gregory, GA; Peabody, JL; Tooley, WH; Willis, MM, 1978)
"Tolazoline is an effective treatment of severe resistant hypoxemia in preterm infants who are already on vigorous ventilatory support."1.31Efficacy and safety of tolazoline for treatment of severe hypoxemia in extremely preterm infants. ( Bada, HS; Korones, SB; Nuntnarumit, P; Yang, W, 2002)
"Pretreatment with dipyridamole did not enhance the pulmonary vasodilation induced by Neb-NP, but did reduce systemic arterial pressure."1.30Effects of nebulized nitroprusside on pulmonary and systemic hemodynamics during pulmonary hypertension in piglets. ( Bell, A; Hipps, R; Meadow, W; Rudinsky, B, 1998)
"Pulmonary hypertension was associated with nonresponse to surfactant in six premature infants with respiratory distress syndrome."1.29Pulmonary hypertension in respiratory distress syndrome. ( Golan, A; Shinwell, ES; Zalzstein, E; Zmora, E, 1995)
"A 32-year-old woman was diagnosed with ventricular septal defect (VSD) with severe pulmonary hypertension (PH)."1.29[A case of pulmonary hypertensive crisis (PHC) treated with prostaglandin E1 and tolazolin after surgery of ventricular septal defect in an adult]. ( Abe, T; Baba, M; Inoue, S; Komatsu, S; Tsukamoto, M; Urita, R; Yamada, A, 1994)
"If tolazoline treatment did not fulfill the criteria for pulmonary vasodilation, prostacyclin was given by continuous iv infusion at a starting rate of 5 ng/kg/min, followed by 10 ng/kg/min."1.28Effects of tolazoline and prostacyclin on pulmonary hypertension in infants after cardiac surgery. ( Huth, R; Iversen, S; Jüngst, BK; Oelert, H; Schranz, D; Wippermann, C; Zepp, F; Zimmer, B, 1992)
"Tolazoline treatment of neonates has been reported since 1965."1.27Oliguria and tolazoline pharmacokinetics in the newborn. ( Daniel, CH; Kendig, JW; Ward, RM; Wood, MA, 1986)
"Isosorbide dinitrate was the only drug that elicited any reduction in pulmonary artery pressure; pulmonary vascular resistance decreased modestly."1.26Vasodilators and prostaglandin inhibitors in primary pulmonary hypertension. ( Bambach, D; Fontana, ME; Hermiller, JB; Huss, P; Leier, CV; Magorien, RD; Thompson, MJ; Unverferth, DV, 1982)
"Treatment with isoproterenol and tolazoline was initiated but was unsuccessful: the child died at 18 months."1.26[Primary pulmonary hypertension in children]. ( Bein, G; Jimenez, E; Lange, L; Lichtenstern-Peters, E; Schachinger, H; Schartl, S; Stoltenburg-Didinger, G, 1982)
"In three babies' hypoxemia was present from birth."1.26[Pulmonary hypertension and fetal circulation after severe congenital diaphragmatic hernia (author's transl)]. ( Besson-Leaud, M; Cloup, M; Laufenburger, A; Lavaud, J; Mselati, JC; Pellerin, D; Revillon, Y, 1979)
"Tolazoline was infused directly into the pulmonary circulation via the catheter."1.26Pulmonary artery pressure monitoring in persistent fetal circulation (PFC). ( Amlie, R; Bartlett, RH; Gazzaniga, AB; German, JC; Huxtable, RF; Sperling, DR, 1977)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199057 (78.08)18.7374
1990's12 (16.44)18.2507
2000's3 (4.11)29.6817
2010's1 (1.37)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vakrilova, L1
Radulova, P1
Hitrova, S1
Slancheva, B1
GARDINER, JM1
WIDIMSKY, J2
KASALICKY, J2
VALACH, A1
DEJDAR, R2
VYSLOUZIL, Z1
LUKES, M1
SAMET, P1
BERNSTEIN, WH1
VOGEL, JH6
AVERILL, KH1
POOL, PE1
BLOUNT, SG4
Greenough, A1
Khetriwal, B1
Kelminson, LL2
Cotton, EK2
Yuceoglu, YZ1
Dresdale, DT1
Valensi, QJ1
Narvas, RM1
Gottlieb, NT1
Tikoff, G1
Schmidt, AM1
Tsagaris, TJ1
Peter, RH1
Rubin, L1
Yabek, SM1
Ward, RM2
Drummond, WH3
Lock, JE1
Nomura, F2
Hirose, H2
Matsuda, H2
Shimazaki, Y1
Shimada, Y2
Kawashima, Y2
Gregory, GA2
Heymann, MA2
Phibbs, RA1
Rich, S1
Martinez, J1
Lam, W1
Levy, PS1
Rosen, KM1
Fishman, AP1
Pietra, GG1
Fennell, WH1
Farmer, JA1
Graf, RH1
Young, JB1
Durandy, Y1
Pansard, Y1
Mankikian, B1
Dequirot, A1
Hermiller, JB1
Bambach, D1
Thompson, MJ1
Huss, P1
Fontana, ME1
Magorien, RD1
Unverferth, DV1
Leier, CV1
Lichtenstern-Peters, E1
Bein, G1
Lange, L1
Jimenez, E1
Schachinger, H2
Schartl, S1
Stoltenburg-Didinger, G1
Peabody, JL2
Huch, R1
Huch, A1
Momma, K1
Takao, A1
Ando, M1
Nakazawa, M1
Takamizawa, K1
Bloss, RS1
Turmen, T1
Beardmore, HE1
Aranda, JV1
Goldenring, J1
Franklin, LC1
Golan, A1
Zalzstein, E1
Zmora, E1
Shinwell, ES1
Colonna, F1
Giorgi, R1
Ciana, G1
Benettoni, A1
Welch, JC1
Bridson, JM1
Gibbs, JL1
Inoue, S1
Abe, T1
Yamada, A1
Urita, R1
Baba, M1
Tsukamoto, M1
Komatsu, S1
Brook, MM1
Fineman, JR1
Bolinger, AM1
Wong, AF1
Soifer, SJ1
Roll, C1
Hanssler, L1
Wolfson, MR1
Greenspan, JS1
Shaffer, TH1
Ichida, F1
Uese, K1
Hashimoto, I1
Hamamichi, Y1
Tsubata, S1
Fukahara, K1
Murakami, A1
Miyawaki, T1
Meadow, W1
Rudinsky, B1
Bell, A1
Hipps, R1
Suematsu, Y1
Yagu, K1
Egami, J1
Yoda, H1
Tsuchiya, K1
Nuntnarumit, P1
Korones, SB1
Yang, W1
Bada, HS1
Omeñaca, F1
Navarro, C1
Barrio, C1
Pérez Rodríguez, J1
García Frías, E1
Quero, J1
Moreno, F1
Mselati, JC1
Besson-Leaud, M1
Revillon, Y1
Laufenburger, A1
Lavaud, J1
Cloup, M1
Pellerin, D1
Wheller, J1
George, BL1
Mulder, DG1
Jarmakani, JM1
Laloum, D1
Bonte, JB1
Kobilinsky, G1
Venezia, R1
German, JC1
Bartlett, RH1
Gazzaniga, AB1
Huxtable, RF1
Amlie, R1
Sperling, DR1
Willis, MM1
Tooley, WH1
Monin, P1
Vert, P1
Peckham, GJ1
Fox, WW1
Collins, DL1
Pomerance, JJ1
Travis, KW1
Turner, SW1
Pappelbaum, SJ1
Levy, RJ1
Rosenthal, A1
Freed, MD1
Smith, CD1
Eraklis, A1
Nadas, AS1
Schranz, D1
Zepp, F1
Iversen, S1
Wippermann, C1
Huth, R1
Zimmer, B1
Jüngst, BK1
Oelert, H1
Ford, WD1
Sen, S1
Barker, AP1
Lee, CM1
Yamaki, S2
Ogata, H2
Haneda, K2
Mohri, H1
Bush, A1
Busst, CM1
Knight, WB1
Shinebourne, EA1
Rodríguez Santana, JR1
Suárez, E1
Sifontes, JE1
Gotay, F1
Mayol, PM1
Pérez, C1
Salgado-Escobar, JL1
Ledesma-Velasco, M1
Munayer-Calderón, J1
Núñez-Garduño, D1
Salas-López, ME1
Rodríguez-Hernández, L1
Ito, T1
Suzuki, Y1
Ishizawa, E1
Ohara, T1
Netz, H1
Nishigaki, K1
Nakano, S1
Kishimoto, H1
Butt, W1
Auldist, A1
McDougall, P1
Duncan, A1
Daniel, CH1
Kendig, JW1
Wood, MA1
Wilson, RG1
George, RJ1
McCormick, WJ1
Raine, PA1
Grover, RF1
Jamieson, G1
Dibbins, AW1
Wiener, ES1
Yoran, C1
Glassman, E1
Both, A1
Abrahamsen, AM1
Grendahl, H1
Müller, C1
Lenz, J1
Hartel, W1
Schuster, G1
Kohlhepp, E1
Moulder, PV1
Harrison, RW1
Cassels, DE1
Long, ET1
Covell, JW1
Rams, JJ1
Daicoff, GR1
Kuzman, WJ1
Satyanarayana Rao, BN1
Moller, JH1
Edwards, JE1

Reviews

8 reviews available for tolazoline and Hypertension, Pulmonary

ArticleYear
[Pulmonary hypertension of the newborn--recent advances in the management and treatment].
    Akusherstvo i ginekologiia, 2014, Volume: 53, Issue:4

    Topics: Antioxidants; Bronchodilator Agents; Extracorporeal Membrane Oxygenation; Humans; Hypertension, Pulm

2014
Pulmonary hypertension in the newborn.
    Paediatric respiratory reviews, 2005, Volume: 6, Issue:2

    Topics: Calcium Channel Blockers; Epoprostenol; Extracorporeal Membrane Oxygenation; Humans; Hypertension, P

2005
The pharmacologic control of the pulmonary circulation in pulmonary hypertension.
    Advances in internal medicine, 1984, Volume: 29

    Topics: Acetylcholine; Adult; Aminophylline; Calcium Channel Blockers; Diazoxide; Female; Humans; Hydralazin

1984
Neonatal cyanosis. Reappraisal of response to 100% oxygen breathing.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:9

    Topics: Adult; Age Factors; Blood Pressure; Child; Cyanosis; Diagnosis, Differential; Heart Defects, Congeni

1984
Pharmacology of tolazoline.
    Clinics in perinatology, 1984, Volume: 11, Issue:3

    Topics: Adult; Age Factors; Animals; Cardiovascular System; Child; Child, Preschool; Guinea Pigs; Half-Life;

1984
Neonatal 'pulmonary vasodilator' drugs. Current status.
    Developmental pharmacology and therapeutics, 1984, Volume: 7, Issue:1

    Topics: Acetylcholine; Animals; Calcium Channel Blockers; Cardiac Output; Catecholamines; Humans; Hypertensi

1984
Persistent pulmonary hypertension of the neonate (persistent fetal circulation syndrome).
    Advances in pediatrics, 1983, Volume: 30

    Topics: Acetylcholine; Calcium; Catecholamines; Epoprostenol; Homeostasis; Humans; Hypertension, Pulmonary;

1983
Primary pulmonary hypertension.
    Annual review of medicine, 1980, Volume: 31

    Topics: Acetylcholine; Aminorex; Diet; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Isoproterenol;

1980

Trials

4 trials available for tolazoline and Hypertension, Pulmonary

ArticleYear
Use of ATP-MgCl2 in the evaluation and treatment of children with pulmonary hypertension secondary to congenital heart defects.
    Circulation, 1994, Volume: 90, Issue:3

    Topics: Adenosine Triphosphate; Blood Pressure; Cardiac Catheterization; Cardiac Surgical Procedures; Female

1994
Comparison of the haemodynamic effects of epoprostenol (prostacyclin) and tolazoline.
    British heart journal, 1988, Volume: 60, Issue:2

    Topics: Blood Pressure; Child; Child, Preschool; Clinical Trials as Topic; Epoprostenol; Heart Rate; Hemodyn

1988
[Vasodilation in children with left-right shunt. Effect of tolazoline].
    Fortschritte der Medizin, 1986, Mar-13, Volume: 104, Issue:10

    Topics: Child; Child, Preschool; Heart Defects, Congenital; Hemodynamics; Humans; Hypertension, Pulmonary; I

1986
Therapeutic enigma of unilateral pulmonary artery coarctation in pulmonary hypertension.
    Annals of surgery, 1965, Volume: 162, Issue:4

    Topics: Adolescent; Adult; Angiocardiography; Blood Circulation; Child; Child, Preschool; Clinical Trials as

1965

Other Studies

61 other studies available for tolazoline and Hypertension, Pulmonary

ArticleYear
The effect of priscol in pulmonary hypertension.
    Australasian annals of medicine, 1954, Volume: 3, Issue:1

    Topics: Hypertension; Hypertension, Pulmonary; Sympatholytics; Tolazoline

1954
Effect of priscol on the pulmonary circulation in cor pulmonale.
    British heart journal, 1960, Volume: 22

    Topics: Chronic Disease; Humans; Hypertension, Pulmonary; Pulmonary Circulation; Pulmonary Heart Disease; Sy

1960
LOSS OF REACTIVITY OF THE PULMONARY VASCULAR BED IN PRIMARY PULMONARY HYPERTENSION.
    American heart journal, 1963, Volume: 66

    Topics: Acetylcholine; Blood Pressure; Blood Vessels; Cardiac Catheterization; Cardiomegaly; Digoxin; Famili

1963
THE EFFECT OF MUSCULAR EXERCISE, OXYGEN INHALATION, SERPASIL AND PRISCOL ON THE LESSER CIRCULATION IN SILICOSIS.
    Cor et vasa, 1963, Volume: 5

    Topics: Cardiac Catheterization; Humans; Hypertension; Hypertension, Pulmonary; Lung; Oxygen; Physical Exert

1963
EXPERIMENTAL PULMONARY ARTERIAL HYPERTENSION IN THE NEWBORN CALF.
    Circulation research, 1963, Volume: 13

    Topics: Acetylcholine; Animals; Animals, Newborn; Atropine; Cattle; Guanethidine; Hypertension; Hypertension

1963
MASKED INFUNDIBULAR PULMONARY OBSTRUCTION IN VENTRICULAR SEPTAL DEFECT WITH PULMONARY HYPERTENSION.
    Circulation, 1965, Volume: 31

    Topics: Adolescent; Angiocardiography; Cardiac Catheterization; Cardiac Surgical Procedures; Cardiomyopathie

1965
The reversibility of pulmonary hypertension in patients with cystic fibrosis. Observations on the effects of tolazoline hydrochloride.
    Pediatrics, 1967, Volume: 39, Issue:1

    Topics: Acetylcholine; Adult; Cardiac Catheterization; Child; Child, Preschool; Cystic Fibrosis; Female; Hum

1967
Pulmonary hypertension during sleep.
    American journal of diseases of children (1960), 1967, Volume: 113, Issue:5

    Topics: Adolescent; Adult; Blood Pressure Determination; Cardiac Catheterization; Child; Child, Preschool; C

1967
Primary pulmonary hypertension with hoarseness and massive (fatal) hemoptysis. Review of the literature and report of a case.
    Vascular diseases, 1967, Volume: 4, Issue:5

    Topics: Acetylcholine; Adult; Angiocardiography; Anticoagulants; Child, Preschool; Electrocardiography; Fema

1967
Isoproterenol-induced right ventricular infundibular obstruction. Study in adult with a large ventricular septal defect.
    The American journal of cardiology, 1967, Volume: 20, Issue:6

    Topics: Adult; Blood Pressure; Cardiac Catheterization; Heart Diseases; Heart Septal Defects, Ventricular; H

1967
[Postoperative pulmonary hypertensive crisis in a case of transposition of the great arteries (type I): the effectiveness of tolazoline hydrochloride].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1984, Volume: 32, Issue:4

    Topics: Female; Humans; Hypertension, Pulmonary; Infant; Postoperative Complications; Tolazoline; Transposit

1984
The independent effects of hyperventilation, tolazoline, and dopamine on infants with persistent pulmonary hypertension.
    The Journal of pediatrics, 1981, Volume: 98, Issue:4

    Topics: Alkalosis, Respiratory; Blood Pressure; Carbon Dioxide; Cardiac Catheterization; Catheterization; Do

1981
Reassessment of the effects of vasodilator drugs in primary pulmonary hypertension: guidelines for determining a pulmonary vasodilator response.
    American heart journal, 1983, Volume: 105, Issue:1

    Topics: Adult; Blood Pressure; Cardiac Catheterization; Cardiac Output; Diazoxide; Female; Humans; Hydralazi

1983
Unanticipated response to alpha-adrenergic blockade in pulmonary hypertension.
    Chest, 1982, Volume: 81, Issue:1

    Topics: Adult; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Tolazoline; Vascular Resistance

1982
[Comparative effects of tolazoline and nifedipine on hypoxic pulmonary arterial hypertension in the dog (author's transl)].
    Le Poumon et le coeur, 1982, Volume: 38, Issue:1

    Topics: Animals; Dogs; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary Circulation; Pyridines; Tolaz

1982
Vasodilators and prostaglandin inhibitors in primary pulmonary hypertension.
    Annals of internal medicine, 1982, Volume: 97, Issue:4

    Topics: Adolescent; Adult; Aspirin; Diazoxide; Dipyridamole; Female; Hemodynamics; Humans; Hydralazine; Hype

1982
[Primary pulmonary hypertension in children].
    Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:11

    Topics: Cardiac Catheterization; Electrocardiography; Humans; Hypertension, Pulmonary; Infant; Isoproterenol

1982
Use of tcPO2 for evaluation of right to left shunts in patent ductus arteriosus.
    Journal of perinatal medicine, 1981, Volume: 9 Suppl 1

    Topics: Cardiography, Impedance; Ductus Arteriosus, Patent; Heart Rate; Humans; Hypertension, Pulmonary; Inf

1981
Natural and post-operative history of pulmonary vascular obstruction associated with ventricular septal defect.
    Japanese circulation journal, 1981, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Constriction, Pathologic; Heart Septal Defe

1981
Tolazoline therapy for persistent pulmonary hypertension after congenital diaphragmatic hernia repair.
    The Journal of pediatrics, 1980, Volume: 97, Issue:6

    Topics: Blood Gas Analysis; Diaphragmatic Eventration; Female; Humans; Hypertension, Pulmonary; Infant, Newb

1980
Cimetidine and pulmonary hypertension.
    Pediatrics, 1980, Volume: 66, Issue:6

    Topics: Cimetidine; Guanidines; Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Newborn, Diseases;

1980
Pulmonary hypertension in respiratory distress syndrome.
    Pediatric pulmonology, 1995, Volume: 19, Issue:4

    Topics: Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Premature, Diseases; Respiratory Distress

1995
[Efficacy of magnesium in a case of neonatal pulmonary hypertension refractory to the usual therapies].
    Minerva pediatrica, 1994, Volume: 46, Issue:12

    Topics: Asphyxia Neonatorum; Epoprostenol; Female; Humans; Hyaline Membrane Disease; Hypertension, Pulmonary

1994
Endotracheal tolazoline for severe persistent pulmonary hypertension of the newborn.
    British heart journal, 1995, Volume: 73, Issue:1

    Topics: Acidosis; Administration, Topical; Humans; Hyaline Membrane Disease; Hypertension, Pulmonary; Hypoxi

1995
[A case of pulmonary hypertensive crisis (PHC) treated with prostaglandin E1 and tolazolin after surgery of ventricular septal defect in an adult].
    Kyobu geka. The Japanese journal of thoracic surgery, 1994, Volume: 47, Issue:12

    Topics: Adult; Alprostadil; Arthralgia; Drug Therapy, Combination; Female; Heart Septal Defects, Ventricular

1994
[Interaction of tolazoline and cimetidine in persistent fetal circulation of the newborn infant].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1993, Volume: 141, Issue:4

    Topics: Blood Pressure; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Humans;

1993
Pulmonary administration of vasoactive substances by perfluorochemical ventilation.
    Pediatrics, 1996, Volume: 97, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Acetylcholine; Acid-Base Equilibrium; Administration, Inhalation

1996
Acute effect of oral prostacyclin and inhaled nitric oxide on pulmonary hypertension in children.
    Journal of cardiology, 1997, Volume: 29, Issue:4

    Topics: Administration, Inhalation; Administration, Oral; Child, Preschool; Epoprostenol; Heart Defects, Con

1997
Effects of nebulized nitroprusside on pulmonary and systemic hemodynamics during pulmonary hypertension in piglets.
    Pediatric research, 1998, Volume: 44, Issue:2

    Topics: Administration, Inhalation; Aerosols; Animals; Blood Gas Analysis; Cyclic GMP; Dipyridamole; Hemodyn

1998
[A case of Down syndrome with ventricular septal defect and hemodynamical Eisenmenger syndrome].
    Kyobu geka. The Japanese journal of thoracic surgery, 2001, Volume: 54, Issue:5

    Topics: Down Syndrome; Eisenmenger Complex; Female; Heart Septal Defects, Ventricular; Humans; Hypertension,

2001
Efficacy and safety of tolazoline for treatment of severe hypoxemia in extremely preterm infants.
    Pediatrics, 2002, Volume: 109, Issue:5

    Topics: Blood Pressure; Blood Proteins; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Gestationa

2002
[Meconium aspiration syndrome with severe hypoxemia. Treatment with a pulmonary vasodilator (tolarzoline) (author's transl)].
    Anales espanoles de pediatria, 1979, Volume: 12, Issue:2

    Topics: Ductus Arteriosus, Patent; Female; Humans; Hyaline Membrane Disease; Hypertension, Pulmonary; Hypoxi

1979
[Pulmonary hypertension and fetal circulation after severe congenital diaphragmatic hernia (author's transl)].
    Chirurgie pediatrique, 1979, Volume: 20, Issue:1

    Topics: Ductus Arteriosus, Patent; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypert

1979
Diagnosis and management of postoperative pulmonary hypertensive crisis.
    Circulation, 1979, Volume: 60, Issue:7

    Topics: Heart Septal Defects, Ventricular; Humans; Hypertension, Pulmonary; Hyperventilation; Infant; Infant

1979
[Refractory hypoxemia in the newborn. Treatment with tolazoline].
    Archives francaises de pediatrie, 1979, Volume: 36, Issue:10

    Topics: Female; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; Infant, Newborn, Diseases; Lung;

1979
Pulmonary artery pressure monitoring in persistent fetal circulation (PFC).
    Journal of pediatric surgery, 1977, Volume: 12, Issue:6

    Topics: Blood Pressure; Ductus Arteriosus, Patent; Female; Hernia, Diaphragmatic; Humans; Hypertension, Pulm

1977
Transcutaneous oxygen tension in sick infants.
    The American review of respiratory disease, 1978, Volume: 118, Issue:1

    Topics: Blood Pressure; Electrodes; Evaluation Studies as Topic; Heart Defects, Congenital; Heart Rate; Huma

1978
[The persistence of foetal circulation. Neonatal pulmonary arterial hypertension. Favourable action of tolazoline (author's transl)].
    La Nouvelle presse medicale, 1978, Sep-23, Volume: 7, Issue:32

    Topics: Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Newborn, Diseas

1978
Physiologic factors affecting pulmonary artery pressure in infants with persistent pulmonary hypertension.
    The Journal of pediatrics, 1978, Volume: 93, Issue:6

    Topics: Blood Pressure; Carbon Dioxide; Cardiac Catheterization; Catheters, Indwelling; Humans; Hypertension

1978
A new approach to congenital posterolateral diaphragmatic hernia.
    Journal of pediatric surgery, 1977, Volume: 12, Issue:2

    Topics: Acetylcholine; Blood Gas Analysis; Chlorpromazine; Ductus Arteriosus, Patent; Hernia, Diaphragmatic;

1977
Persistent pulmonary hypertension in a newborn with congenital diaphragmeatic hernia: successful management with tolazoline.
    Pediatrics, 1977, Volume: 60, Issue:5

    Topics: Hernia, Diaphragmatic; Humans; Hypertension, Pulmonary; Infant, Newborn; Male; Pulmonary Circulation

1977
Effects of tolazoline and prostacyclin on pulmonary hypertension in infants after cardiac surgery.
    Critical care medicine, 1992, Volume: 20, Issue:9

    Topics: Drug Evaluation; Epoprostenol; Heart Defects, Congenital; Hemodynamics; Humans; Hypertension, Pulmon

1992
Pulmonary hypertension in lambs with congenital diaphragmatic hernia: vasodilator prostaglandins, isoprenaline, and tolazoline.
    Journal of pediatric surgery, 1990, Volume: 25, Issue:5

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Disease Models, Animal; Hernia, Diaphragmatic; Hernias

1990
Indications for open lung biopsy in patients with ventricular septal defect and/or patent ductus arteriosus with pulmonary hypertension.
    Heart and vessels, 1990, Volume: 5, Issue:3

    Topics: Adult; Biopsy; Child; Child, Preschool; Ductus Arteriosus, Patent; Heart Septal Defects, Ventricular

1990
Neonatal pulmonary hypertension: unusual presentation.
    Boletin de la Asociacion Medica de Puerto Rico, 1986, Volume: 78, Issue:9

    Topics: Female; Humans; Hypertension, Pulmonary; Infant, Newborn; Respiration, Artificial; Tolazoline

1986
[Oxygen and tolazoline as vasodilators in pulmonary arterial hypertension secondary to high pulmonary blood flow].
    Boletin medico del Hospital Infantil de Mexico, 1987, Volume: 44, Issue:3

    Topics: Child; Child, Preschool; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant;

1987
[Oxygen test and tolazoline test in patients with ventricular septal defect and/or patent ductus arteriosus and pulmonary hypertension].
    Kyobu geka. The Japanese journal of thoracic surgery, 1987, Volume: 40, Issue:11

    Topics: Adolescent; Adult; Biopsy; Child; Child, Preschool; Ductus Arteriosus, Patent; Heart Septal Defects,

1987
[Causation and management of pulmonary hypertensive crisis after open heart surgery].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1986, Volume: 34, Issue:2

    Topics: Adult; Child, Preschool; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant,

1986
Duodenal ulceration: a complication of tolazoline therapy.
    Australian paediatric journal, 1986, Volume: 22, Issue:3

    Topics: Duodenal Ulcer; Female; Humans; Hypertension, Pulmonary; Infant, Newborn; Peptic Ulcer Perforation;

1986
Oliguria and tolazoline pharmacokinetics in the newborn.
    Pediatrics, 1986, Volume: 77, Issue:3

    Topics: Animals; Anuria; Half-Life; Humans; Hyaline Membrane Disease; Hypertension, Pulmonary; Infant, Newbo

1986
Duodenal perforation associated with tolazoline.
    Archives of disease in childhood, 1985, Volume: 60, Issue:9

    Topics: Duodenal Diseases; Humans; Hypertension, Pulmonary; Infant, Newborn; Intestinal Perforation; Male; T

1985
Long-term physiologic observations in patients with ventricular septal defect and increased pulmonary vascular resistance (with 2 color plates).
    Advances in cardiology, 1974, Volume: 11, Issue:00

    Topics: Adolescent; Adult; Biopsy; Blood Pressure; Cardiac Catheterization; Cardiac Output; Child; Child, Pr

1974
Mortality from neonatal diaphragmatic hernia.
    Journal of pediatric surgery, 1974, Volume: 9, Issue:5

    Topics: Acidosis, Respiratory; Bicarbonates; Blood; Blood Volume; Carbon Dioxide; Cardiac Catheterization; C

1974
The paradoxic effect of tolazoline hydrochloride on pulmonary hypertension of mitral stenosis.
    Chest, 1973, Volume: 63, Issue:5

    Topics: Adult; Blood Pressure; Cardiac Catheterization; Cardiac Output; Humans; Hypertension, Pulmonary; Inj

1973
[Therapy of primary pulmonary hypertension].
    Zeitschrift fur Kreislaufforschung, 1970, Volume: 59, Issue:10

    Topics: Acetylcholine; Amino Alcohols; Carbachol; Child; Diazepam; Diazoxide; Female; Humans; Hypertension,

1970
Hemodynamic effects of tolazoline. Studies in normal subjects and patients with mitral valvular disease, congenital heart disease and primary pulmonary hypertension.
    Acta medica Scandinavica, 1971, Volume: 190, Issue:3

    Topics: Adolescent; Adult; Blood Flow Velocity; Blood Pressure; Cardiac Catheterization; Female; Heart Defec

1971
[Effect of lung resection on the decrease of hypertension in the pulmonary artery by means of drugs].
    Thoraxchirurgie, vaskulare Chirurgie, 1970, Volume: 18, Issue:1

    Topics: Acetylcholine; Aminophylline; Blood Pressure Determination; Hypertension, Pulmonary; Nicotinic Acids

1970
Primary pulmonary hypertension.
    Medical times, 1970, Volume: 98, Issue:3

    Topics: Adolescent; Adult; Anticoagulants; Cardiac Catheterization; Cardiovascular Diseases; Child; Child, P

1970
Pulmonary hypertension.
    Modern concepts of cardiovascular disease, 1967, Volume: 36, Issue:11

    Topics: Altitude; Child; Child, Preschool; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infan

1967
Reversibility of pulmonary hypertension.
    British medical journal, 1969, Jan-25, Volume: 1, Issue:5638

    Topics: Humans; Hypertension, Pulmonary; Hypoventilation; Pulmonary Artery; Tolazoline; Vascular Diseases

1969
Primary pulmonary hypertension in a child. Response to pharmacologic agents.
    Circulation, 1969, Volume: 40, Issue:4

    Topics: Acetylcholine; Blood Pressure; Cardiac Catheterization; Cardiac Output; Child; Heart Ventricles; Hex

1969