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tolazoline and Gastrointestinal Hemorrhage

tolazoline has been researched along with Gastrointestinal Hemorrhage in 16 studies

Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.

Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"Forty-six neonates with hypoxemia were treated with tolazoline, a pulmonary vasodilator, within the first two days of life."5.26Neonatal hypoxia and pulmonary vasospasm: response to tolazoline. ( Bartoletti, AL; Goetzman, BW; Hackel, A; Johnson, JD; Merten, DF; Silverman, NH; Sunshine, P; Wennberg, RP, 1976)
"There were 47 seriously-ill neonates with medical causes of respiratory distress and 10 infants with severe respiratory distress secondary to a congenital diaphragmatic hernia treated with tolazoline according to a strict protocol designed to manage persistent fetal circulation (PFC)."3.66An analysis of tolazoline therapy in the critically-ill neonate. ( Bryson, CQ; Bull, MJ; Gresham, EL; Grosfeld, JL; Lemons, JA; Schreiner, RL; Stevens, DC; Weber, TR, 1980)
"We randomly assigned 24 neonates with hypoxemia to receive tolazoline hydrochloride."2.66Bolus and continuous infusion of tolazoline in neonates with hypoxemia. ( McMillan, DD; Sauve, RS, 1986)
"Forty-six neonates with hypoxemia were treated with tolazoline, a pulmonary vasodilator, within the first two days of life."1.26Neonatal hypoxia and pulmonary vasospasm: response to tolazoline. ( Bartoletti, AL; Goetzman, BW; Hackel, A; Johnson, JD; Merten, DF; Silverman, NH; Sunshine, P; Wennberg, RP, 1976)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's2 (12.50)18.2507
2000's3 (18.75)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Humphrey, M1
Kennon, S1
Pramanik, AK1
Stevens, DC1
Schreiner, RL1
Bull, MJ1
Bryson, CQ1
Lemons, JA1
Gresham, EL1
Grosfeld, JL1
Weber, TR1
Dillard, RG1
Rösch, J2
Keller, FS2
Wawrukiewicz, AS1
Krippaehne, WW1
Dotter, CT2
Kuint, J1
Linder, N1
Reichman, B1
Huang, CB1
Huang, SC1
Bloomfeld, RS1
Smith, TP2
Schneider, AM1
Rockey, DC1
Ryan, JM1
Key, SM1
Dumbleton, SA1
Smith, DC1
Watkins, GE1
Menzel, K1
Schambach, K1
Töpke, B1
Goetzman, BW1
Sunshine, P1
Johnson, JD1
Wennberg, RP1
Hackel, A1
Merten, DF1
Bartoletti, AL1
Silverman, NH1
McMillan, DD1
Sauve, RS1
Kozak, BE1
Okabe, S1
Saziki, R1
Takagi, K1
Turcotte, JG1
Child, CG1
Silverman, AG1
Wilner, HI1
Okun, R1

Reviews

1 review available for tolazoline and Gastrointestinal Hemorrhage

ArticleYear
[The patent ductus arteriosus from a perinatological viewpoint].
    Zeitschrift fur arztliche Fortbildung, 1978, May-15, Volume: 72, Issue:10

    Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Fetus; Gastrointestinal Hemorrhage; Growth; Hu

1978

Trials

1 trial available for tolazoline and Gastrointestinal Hemorrhage

ArticleYear
Bolus and continuous infusion of tolazoline in neonates with hypoxemia.
    Developmental pharmacology and therapeutics, 1986, Volume: 9, Issue:3

    Topics: Female; Gastrointestinal Hemorrhage; Humans; Hypotension; Hypoxia; Infant, Newborn; Infusions, Paren

1986

Other Studies

14 other studies available for tolazoline and Gastrointestinal Hemorrhage

ArticleYear
Hypermagnesemia from antacid administration in a newborn infant.
    The Journal of pediatrics, 1981, Volume: 98, Issue:2

    Topics: Antacids; Gastrointestinal Hemorrhage; Humans; Infant, Newborn; Infant, Newborn, Diseases; Magnesium

1981
An analysis of tolazoline therapy in the critically-ill neonate.
    Journal of pediatric surgery, 1980, Volume: 15, Issue:6

    Topics: Erythema; Gastrointestinal Hemorrhage; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hu

1980
Fatal gastrointestinal hemorrhage in a neonate treated with tolazoline.
    Clinical pediatrics, 1982, Volume: 21, Issue:12

    Topics: Gastrointestinal Hemorrhage; Humans; Infant, Newborn; Infant, Newborn, Diseases; Meconium; Pneumonia

1982
Pharmacoangiography in the diagnosis of recurrent massive lower gastrointestinal bleeding.
    Radiology, 1982, Volume: 145, Issue:3

    Topics: Aged; Angiography; Female; Gastrointestinal Hemorrhage; Heparin; Humans; Middle Aged; Recurrence; St

1982
Hypoxemia associated with cimetidine therapy in a newborn infant.
    American journal of perinatology, 1996, Volume: 13, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Cimetidine; Female; Fetal Diseases; Gastrointestinal Hemorrhage

1996
Caution with use of cimetidine in tolazoline induced upper gastrointestinal bleeding.
    Changgeng yi xue za zhi, 1996, Volume: 19, Issue:3

    Topics: Cimetidine; Drug Interactions; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Infant

1996
Provocative angiography in patients with gastrointestinal hemorrhage of obscure origin.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Female; Gastrointestinal Hemorrhage; Heparin; Humans; M

2000
Nonlocalized lower gastrointestinal bleeding: provocative bleeding studies with intraarterial tPA, heparin, and tolazoline.
    Journal of vascular and interventional radiology : JVIR, 2001, Volume: 12, Issue:11

    Topics: Adult; Aged; Angiography; Female; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Heparin; Humans;

2001
Re: Nonlocalized lower gastrointestinal bleeding: provocative bleeding studies with intraarterial tPA, heparin, and tolazoline.
    Journal of vascular and interventional radiology : JVIR, 2002, Volume: 13, Issue:5

    Topics: Anticoagulants; Embolization, Therapeutic; Gastrointestinal Hemorrhage; Heparin; Humans; Infusions,

2002
Neonatal hypoxia and pulmonary vasospasm: response to tolazoline.
    The Journal of pediatrics, 1976, Volume: 89, Issue:4

    Topics: Female; Gastrointestinal Hemorrhage; Humans; Hypoxia; Infant, Newborn; Infant, Newborn, Diseases; Lu

1976
Interventional angiography in the diagnosis of acute lower gastrointestinal bleeding.
    European journal of radiology, 1986, Volume: 6, Issue:2

    Topics: Aged; Angiography; Anticoagulants; Carcinoid Tumor; Catheters, Indwelling; Female; Fibrinolytic Agen

1986
Effects of adrenergic blocking agents on gastric secretion and stress-induced gastric ulcer in rats.
    Japanese journal of pharmacology, 1970, Volume: 20, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Depression, Chemical; Dibenzylch

1970
Idiopathic extrahepatic portal hypertension in adults.
    American journal of surgery, 1972, Volume: 123, Issue:1

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bi

1972
A case of gastrointestinal bleeding following the use of tolazoline.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:2

    Topics: Aged; Foot Diseases; Gangrene; Gastrointestinal Hemorrhage; Humans; Male; Tolazoline

1970