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tolazoline and Diaphragmatic Hernia

tolazoline has been researched along with Diaphragmatic Hernia in 21 studies

Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.

Research Excerpts

ExcerptRelevanceReference
"After antenatal induction of diaphragmatic hernias in fetal lambs, prostaglandins D2, E1, and I2 were compared to tolazoline, or isoprenaline, for the treatment of pulmonary hypertension."7.68Pulmonary hypertension in lambs with congenital diaphragmatic hernia: vasodilator prostaglandins, isoprenaline, and tolazoline. ( Barker, AP; Ford, WD; Lee, CM; Sen, S, 1990)
"After antenatal induction of diaphragmatic hernias in fetal lambs, prostaglandins D2, E1, and I2 were compared to tolazoline, or isoprenaline, for the treatment of pulmonary hypertension."3.68Pulmonary hypertension in lambs with congenital diaphragmatic hernia: vasodilator prostaglandins, isoprenaline, and tolazoline. ( Barker, AP; Ford, WD; Lee, CM; Sen, S, 1990)
"There were 47 seriously-ill neonates with medical causes of respiratory distress and 10 infants with severe respiratory distress secondary to a congenital diaphragmatic hernia treated with tolazoline according to a strict protocol designed to manage persistent fetal circulation (PFC)."3.66An analysis of tolazoline therapy in the critically-ill neonate. ( Bryson, CQ; Bull, MJ; Gresham, EL; Grosfeld, JL; Lemons, JA; Schreiner, RL; Stevens, DC; Weber, TR, 1980)
"Tolazoline did not lower AaDO2 and OI values, but MABP dropped significantly."2.67Persistent pulmonary hypertension in high-risk congenital diaphragmatic hernia patients: incidence and vasodilator therapy. ( Bos, AP; Hazebroek, FW; Koot, VC; Molenaar, JC; Tibboel, D, 1993)
"Infants with congenital diaphragmatic hernia (CDH) die, because their lungs are hypoplastic and their pulmonary vascular resistance remains elevated after birth."1.29High-frequency ventilation in newborn lambs after intra-uterine creation of diaphragmatic hernia. ( Chourrout, Y; Ghnassia, D; Harf, A; Isabey, D; Jaubert, F; Martelli, H; Piquet, J; Revillon, Y; Sidi, D, 1993)
"Two infants had undergone repair of a diaphragmatic hernia and the third had correction of a tracheoesophageal fistula."1.27Persistent fetal circulation in neonates postoperatively: the value of manual ventilation. ( Gaulin, P; Rubin, SZ, 1983)
"After repair of a Bochdalek diaphragmatic hernia, shunting of blood away from the lungs produced progressive hypoxaemia in a neonate."1.27Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations. ( Ford, WD; James, MJ; Walsh, JA, 1984)
"Twenty-two cases of diaphragmatic hernia, presenting from 1978 to 1982, were reviewed."1.27Congenital diaphragmatic hernia and the management of persistent foetal circulation. ( Fong, LV; Pemberton, PJ, 1985)
"The incidence of death from congenital diaphragmatic hernia appears to be unchanged in recent years despite advances in resuscitation, transport, and ventilatory support."1.26Congenital diaphragmatic hernia: pathophysiology and pharmacologic support. ( Aranda, JV; Beardmore, HE; Bloss, RS, 1981)
"In three babies' hypoxemia was present from birth."1.26[Pulmonary hypertension and fetal circulation after severe congenital diaphragmatic hernia (author's transl)]. ( Besson-Leaud, M; Cloup, M; Laufenburger, A; Lavaud, J; Mselati, JC; Pellerin, D; Revillon, Y, 1979)
"Seven infants with progressive hypoxemia were treated with a vasodilator, tolazoline."1.26Congenital diaphragmatic hernia. New concept in management. ( Ford, WD; Maisels, MJ; Naeye, RL; Shochat, SJ; Whitman, V, 1979)
"Tolazoline was infused directly into the pulmonary circulation via the catheter."1.26Pulmonary artery pressure monitoring in persistent fetal circulation (PFC). ( Amlie, R; Bartlett, RH; Gazzaniga, AB; German, JC; Huxtable, RF; Sperling, DR, 1977)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199018 (85.71)18.7374
1990's3 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gaulin, P1
Rubin, SZ1
Ihara, K1
Maeda, S1
Otani, M1
Sasako, Y1
Kinoshita, M1
Nakaba, H1
Takao, T1
Miyagawa, S1
Kashii, H1
Shiga, S1
Ford, WD3
James, MJ1
Walsh, JA1
Sumner, E1
Frank, JD1
Stevens, DC1
Schreiner, RL1
Bull, MJ1
Bryson, CQ1
Lemons, JA1
Gresham, EL1
Grosfeld, JL1
Weber, TR1
Wiener, ES2
Bloss, RS2
Aranda, JV2
Beardmore, HE2
Ein, SH1
Barker, G1
Olley, P1
Shandling, B1
Simpson, JS1
Stephens, CA1
Filler, RM1
Lassaletta, L1
Ros, Z1
Queizán, A1
Benavent, M1
Cabrera, R1
Jaureguizar, E1
Martínez, A1
Bos, AP1
Tibboel, D1
Koot, VC1
Hazebroek, FW1
Molenaar, JC1
Revillon, Y2
Sidi, D1
Chourrout, Y1
Martelli, H1
Ghnassia, D1
Piquet, J1
Isabey, D1
Harf, A1
Jaubert, F1
Mselati, JC1
Besson-Leaud, M1
Laufenburger, A1
Lavaud, J1
Cloup, M1
Pellerin, D1
Shochat, SJ1
Naeye, RL1
Whitman, V1
Maisels, MJ1
German, JC1
Bartlett, RH1
Gazzaniga, AB1
Huxtable, RF1
Amlie, R1
Sperling, DR1
Collins, DL1
Pomerance, JJ1
Travis, KW1
Turner, SW1
Pappelbaum, SJ1
Levy, RJ1
Rosenthal, A1
Freed, MD1
Smith, CD1
Eraklis, A1
Nadas, AS1
Sen, S1
Barker, AP1
Lee, CM1
Brereton, RJ1
Kumar, D1
Spitz, L1
Fong, LV1
Pemberton, PJ1
Dibbins, AW1

Trials

1 trial available for tolazoline and Diaphragmatic Hernia

ArticleYear
Persistent pulmonary hypertension in high-risk congenital diaphragmatic hernia patients: incidence and vasodilator therapy.
    Journal of pediatric surgery, 1993, Volume: 28, Issue:11

    Topics: Blood Pressure; Combined Modality Therapy; Epoprostenol; Hernia, Diaphragmatic; Hernias, Diaphragmat

1993

Other Studies

20 other studies available for tolazoline and Diaphragmatic Hernia

ArticleYear
Persistent fetal circulation in neonates postoperatively: the value of manual ventilation.
    Canadian journal of surgery. Journal canadien de chirurgie, 1983, Volume: 26, Issue:3

    Topics: Carbon Dioxide; Hernia, Diaphragmatic; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infant,

1983
[A survival case of persistent fetal circulation following surgery of diaphragmatic hernia by ligature of the ductus arteriosus].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1984, Volume: 32, Issue:9

    Topics: Ductus Arteriosus; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newbor

1984
Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations.
    Archives of disease in childhood, 1984, Volume: 59, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Inf

1984
Tolazoline in the treatment of congenital diaphragmatic hernias.
    Archives of disease in childhood, 1981, Volume: 56, Issue:5

    Topics: Carbon Dioxide; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, N

1981
An analysis of tolazoline therapy in the critically-ill neonate.
    Journal of pediatric surgery, 1980, Volume: 15, Issue:6

    Topics: Erythema; Gastrointestinal Hemorrhage; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hu

1980
Congenital posterolateral diaphragmatic hernia: new dimensions in management.
    Surgery, 1982, Volume: 92, Issue:4

    Topics: Chlorpromazine; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn;

1982
Congenital diaphragmatic hernia: pathophysiology and pharmacologic support.
    Surgery, 1981, Volume: 89, Issue:4

    Topics: Animals; Cattle; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn;

1981
Vasodilator response and prediction of survival in congenital diaphragmatic hernia.
    Journal of pediatric surgery, 1981, Volume: 16, Issue:2

    Topics: Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Oxygen; Persiste

1981
The pharmacologic treatment of newborn diaphragmatic hernia--a 2-year evaluation.
    Journal of pediatric surgery, 1980, Volume: 15, Issue:4

    Topics: Acetylcholine; Chlorpromazine; Dopamine; Ductus Arteriosus, Patent; Hernia, Diaphragmatic; Hernias,

1980
[Tolazoline in postoperative period of diaphragmatic hernia (author's transl)].
    Anales espanoles de pediatria, 1980, Volume: 13, Issue:8

    Topics: Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Infant, Newborn,

1980
High-frequency ventilation in newborn lambs after intra-uterine creation of diaphragmatic hernia.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1993, Volume: 3, Issue:3

    Topics: Animals; Animals, Newborn; Female; Hemodynamics; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Cong

1993
[Pulmonary hypertension and fetal circulation after severe congenital diaphragmatic hernia (author's transl)].
    Chirurgie pediatrique, 1979, Volume: 20, Issue:1

    Topics: Ductus Arteriosus, Patent; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypert

1979
Congenital diaphragmatic hernia. New concept in management.
    Annals of surgery, 1979, Volume: 190, Issue:3

    Topics: Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypoxia; Infant, Newborn;

1979
Pulmonary artery pressure monitoring in persistent fetal circulation (PFC).
    Journal of pediatric surgery, 1977, Volume: 12, Issue:6

    Topics: Blood Pressure; Ductus Arteriosus, Patent; Female; Hernia, Diaphragmatic; Humans; Hypertension, Pulm

1977
A new approach to congenital posterolateral diaphragmatic hernia.
    Journal of pediatric surgery, 1977, Volume: 12, Issue:2

    Topics: Acetylcholine; Blood Gas Analysis; Chlorpromazine; Ductus Arteriosus, Patent; Hernia, Diaphragmatic;

1977
Persistent pulmonary hypertension in a newborn with congenital diaphragmeatic hernia: successful management with tolazoline.
    Pediatrics, 1977, Volume: 60, Issue:5

    Topics: Hernia, Diaphragmatic; Humans; Hypertension, Pulmonary; Infant, Newborn; Male; Pulmonary Circulation

1977
Pulmonary hypertension in lambs with congenital diaphragmatic hernia: vasodilator prostaglandins, isoprenaline, and tolazoline.
    Journal of pediatric surgery, 1990, Volume: 25, Issue:5

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Disease Models, Animal; Hernia, Diaphragmatic; Hernias

1990
Diaphragmatic hernia in neonate.
    Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1985, Volume: 40, Issue:2

    Topics: Carbon Dioxide; Dopamine; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant,

1985
Congenital diaphragmatic hernia and the management of persistent foetal circulation.
    Anaesthesia and intensive care, 1985, Volume: 13, Issue:4

    Topics: Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hyperventilation; Infant,

1985
Mortality from neonatal diaphragmatic hernia.
    Journal of pediatric surgery, 1974, Volume: 9, Issue:5

    Topics: Acidosis, Respiratory; Bicarbonates; Blood; Blood Volume; Carbon Dioxide; Cardiac Catheterization; C

1974