tolazoline has been researched along with Cystic Fibrosis in 5 studies
Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tolazoline hydrochloride was also ineffective." | 1.26 | Heart failure in cystic fibrosis. Treatment and prognosis of cor pulmonale with failure of the right side of the heart. ( Boat, TF; Borkat, G; Doershuk, CF; Hirschfeld, SS; Liebman, J; Matthews, LW; Stern, RC, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelminson, LL | 2 |
| Cotton, EK | 2 |
| Vogel, JH | 2 |
| Stern, RC | 1 |
| Borkat, G | 1 |
| Hirschfeld, SS | 1 |
| Boat, TF | 1 |
| Matthews, LW | 1 |
| Liebman, J | 1 |
| Doershuk, CF | 1 |
| Feather, EA | 1 |
| Russell, G | 1 |
| Gibson, LE | 1 |
1 trial available for tolazoline and Cystic Fibrosis
| Article | Year |
|---|---|
Effect of tolazoline hydrochloride on sputum viscosity in cystic fibrosis.
Topics: Adolescent; Adult; Bronchi; Child; Cystic Fibrosis; Female; Humans; Male; Placebos; Pulse; Respirati | 1970 |
4 other studies available for tolazoline and Cystic Fibrosis
| Article | Year |
|---|---|
The reversibility of pulmonary hypertension in patients with cystic fibrosis. Observations on the effects of tolazoline hydrochloride.
Topics: Acetylcholine; Adult; Cardiac Catheterization; Child; Child, Preschool; Cystic Fibrosis; Female; Hum | 1967 |
Pulmonary hypertension during sleep.
Topics: Adolescent; Adult; Blood Pressure Determination; Cardiac Catheterization; Child; Child, Preschool; C | 1967 |
Heart failure in cystic fibrosis. Treatment and prognosis of cor pulmonale with failure of the right side of the heart.
Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Diet, Sodium-Restricted; Digitalis Glyc | 1980 |
The effect of adrenergic stimulation upon sweating in normal children and cystic fibrosis patients.
Topics: Adolescent; Adult; Atropine; Child; Child, Preschool; Cystic Fibrosis; Epinephrine; Humans; Iontopho | 1968 |