tolazoline has been researched along with Abnormality, Heart in 19 studies
Tolazoline: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
tolazoline : A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "If tolazoline treatment did not fulfill the criteria for pulmonary vasodilation, prostacyclin was given by continuous iv infusion at a starting rate of 5 ng/kg/min, followed by 10 ng/kg/min." | 5.28 | Effects of tolazoline and prostacyclin on pulmonary hypertension in infants after cardiac surgery. ( Huth, R; Iversen, S; Jüngst, BK; Oelert, H; Schranz, D; Wippermann, C; Zepp, F; Zimmer, B, 1992) |
| "The hemodynamic effects of acute oral administration of a newly-developed prostacyclin analogue (beraprost sodium; 1-2 micrograms/kg), inhaled nitric oxide (NO; 20 ppm) and tolazoline hydrochloride (1 mg/kg) were measured in 17 children (mean age 1 year and 9 months) with pulmonary hypertension complicating congenital heart disease or primary pulmonary hypertension." | 3.69 | Acute effect of oral prostacyclin and inhaled nitric oxide on pulmonary hypertension in children. ( Fukahara, K; Hamamichi, Y; Hashimoto, I; Ichida, F; Miyawaki, T; Murakami, A; Tsubata, S; Uese, K, 1997) |
| " Some infants with severe, persistent pulmonary hypertension who were receiving an intravascular infusion of tolazoline and infants with mean arterial blood pressures more than 2." | 3.66 | Transcutaneous oxygen tension in sick infants. ( Gregory, GA; Peabody, JL; Tooley, WH; Willis, MM, 1978) |
| "If tolazoline treatment did not fulfill the criteria for pulmonary vasodilation, prostacyclin was given by continuous iv infusion at a starting rate of 5 ng/kg/min, followed by 10 ng/kg/min." | 1.28 | Effects of tolazoline and prostacyclin on pulmonary hypertension in infants after cardiac surgery. ( Huth, R; Iversen, S; Jüngst, BK; Oelert, H; Schranz, D; Wippermann, C; Zepp, F; Zimmer, B, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (78.95) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yabek, SM | 1 |
| Wille, L | 1 |
| Ulmer, HE | 1 |
| Obladen, M | 1 |
| Friedberg, DZ | 1 |
| Van Liere, T | 1 |
| Litwin, SB | 1 |
| Brook, MM | 1 |
| Fineman, JR | 1 |
| Bolinger, AM | 1 |
| Wong, AF | 1 |
| Heymann, MA | 1 |
| Soifer, SJ | 1 |
| Itoh, Y | 1 |
| Kohya, T | 1 |
| Kitabatake, A | 1 |
| Ichida, F | 1 |
| Uese, K | 1 |
| Hashimoto, I | 1 |
| Hamamichi, Y | 1 |
| Tsubata, S | 1 |
| Fukahara, K | 1 |
| Murakami, A | 1 |
| Miyawaki, T | 1 |
| de Geeter, B | 1 |
| Messer, J | 1 |
| Benoit, M | 1 |
| Willard, D | 1 |
| Peabody, JL | 1 |
| Gregory, GA | 1 |
| Willis, MM | 1 |
| Tooley, WH | 1 |
| Boyle, RJ | 1 |
| Oh, W | 1 |
| Monin, P | 1 |
| Vert, P | 1 |
| Schranz, D | 1 |
| Zepp, F | 1 |
| Iversen, S | 1 |
| Wippermann, C | 1 |
| Huth, R | 1 |
| Zimmer, B | 1 |
| Jüngst, BK | 1 |
| Oelert, H | 1 |
| Bush, A | 1 |
| Busst, CM | 1 |
| Knight, WB | 1 |
| Shinebourne, EA | 1 |
| Salgado-Escobar, JL | 1 |
| Ledesma-Velasco, M | 1 |
| Munayer-Calderón, J | 1 |
| Núñez-Garduño, D | 1 |
| Salas-López, ME | 1 |
| Rodríguez-Hernández, L | 1 |
| Netz, H | 1 |
| Nishigaki, K | 1 |
| Hirose, H | 1 |
| Matsuda, H | 1 |
| Nakano, S | 1 |
| Kishimoto, H | 1 |
| Nomura, F | 1 |
| Shimada, Y | 1 |
| Kawashima, Y | 1 |
| Brammell, HL | 1 |
| Vogel, JH | 2 |
| Pryor, R | 1 |
| Blount, SG | 2 |
| Abrahamsen, AM | 1 |
| Grendahl, H | 1 |
| Müller, C | 1 |
| Moulder, PV | 1 |
| Harrison, RW | 1 |
| Cassels, DE | 1 |
| Long, ET | 1 |
| Covell, JW | 1 |
| Rams, JJ | 1 |
| Daicoff, GR | 1 |
2 reviews available for tolazoline and Abnormality, Heart
| Article | Year |
|---|---|
Neonatal cyanosis. Reappraisal of response to 100% oxygen breathing.
Topics: Adult; Age Factors; Blood Pressure; Child; Cyanosis; Diagnosis, Differential; Heart Defects, Congeni | 1984 |
[Measurement of vascular resistance].
Topics: Cardiac Catheterization; Heart Defects, Congenital; Heart Valve Diseases; Humans; Oxygen; Pulmonary | 1997 |
3 trials available for tolazoline and Abnormality, Heart
| Article | Year |
|---|---|
Use of ATP-MgCl2 in the evaluation and treatment of children with pulmonary hypertension secondary to congenital heart defects.
Topics: Adenosine Triphosphate; Blood Pressure; Cardiac Catheterization; Cardiac Surgical Procedures; Female | 1994 |
[Vasodilation in children with left-right shunt. Effect of tolazoline].
Topics: Child; Child, Preschool; Heart Defects, Congenital; Hemodynamics; Humans; Hypertension, Pulmonary; I | 1986 |
Therapeutic enigma of unilateral pulmonary artery coarctation in pulmonary hypertension.
Topics: Adolescent; Adult; Angiocardiography; Blood Circulation; Child; Child, Preschool; Clinical Trials as | 1965 |
14 other studies available for tolazoline and Abnormality, Heart
| Article | Year |
|---|---|
Persistence of fetal circulation in the newborn.
Topics: Diagnosis, Differential; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Persisten | 1981 |
Cor triatriatum.
Topics: Heart Atria; Heart Defects, Congenital; Humans; Infant; Male; Postoperative Complications; Pulmonary | 1981 |
Acute effect of oral prostacyclin and inhaled nitric oxide on pulmonary hypertension in children.
Topics: Administration, Inhalation; Administration, Oral; Child, Preschool; Epoprostenol; Heart Defects, Con | 1997 |
Right-to-left ductal shunt and transcutaneous PO2.
Topics: Blood Gas Analysis; Diagnosis, Differential; Ductus Arteriosus, Patent; Heart Defects, Congenital; H | 1979 |
Transcutaneous oxygen tension in sick infants.
Topics: Blood Pressure; Electrodes; Evaluation Studies as Topic; Heart Defects, Congenital; Heart Rate; Huma | 1978 |
Transcutaneous PO2 monitoring in infants with persistent fetal circulation who are receiving tolazoline therapy.
Topics: Heart Defects, Congenital; Humans; Infant, Newborn; Monitoring, Physiologic; Oxygen; Partial Pressur | 1978 |
[The persistence of foetal circulation. Neonatal pulmonary arterial hypertension. Favourable action of tolazoline (author's transl)].
Topics: Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Infant, Newborn, Diseas | 1978 |
Effects of tolazoline and prostacyclin on pulmonary hypertension in infants after cardiac surgery.
Topics: Drug Evaluation; Epoprostenol; Heart Defects, Congenital; Hemodynamics; Humans; Hypertension, Pulmon | 1992 |
Cardiovascular effects of tolazoline and ranitidine.
Topics: Blood Circulation; Blood Pressure; Child; Child, Preschool; Drug Therapy, Combination; Heart Defects | 1987 |
[Oxygen and tolazoline as vasodilators in pulmonary arterial hypertension secondary to high pulmonary blood flow].
Topics: Child; Child, Preschool; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant; | 1987 |
[Causation and management of pulmonary hypertensive crisis after open heart surgery].
Topics: Adult; Child, Preschool; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant, | 1986 |
The Eisenmenger syndrome. A clinical and physiologic reappraisal.
Topics: Adolescent; Adult; Angina Pectoris; Blood Pressure; Cardiac Catheterization; Child; Child, Preschool | 1971 |
Hemodynamic effects of tolazoline. Studies in normal subjects and patients with mitral valvular disease, congenital heart disease and primary pulmonary hypertension.
Topics: Adolescent; Adult; Blood Flow Velocity; Blood Pressure; Cardiac Catheterization; Female; Heart Defec | 1971 |
Pulmonary hypertension.
Topics: Altitude; Child; Child, Preschool; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infan | 1967 |