tolazamide has been researched along with Insulin Resistance in 3 studies
Tolazamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
tolazamide : An N-sulfonylurea that is 1-tosylurea in which a hydrogen attached to the nitrogen at position 3 is replaced by an azepan-1-yl group. A hypoglycemic agent, it is used for the treatment of type 2 diabetes mellitus.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glyburide and other sulfonylureas consistently enhance receptor binding in cells from patients with non-insulin-dependent diabetes mellitus, whereas no effects and mixed effects have been demonstrated in cells from patients with insulin-dependent diabetes mellitus and in normal cells, respectively." | 3.67 | Dual actions of sulfonylureas and glyburide. Receptor and post-receptor effects. ( Gavin, JR, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Firth, RG | 1 |
| Bell, PM | 1 |
| Rizza, RA | 1 |
| Skillman, CA | 1 |
| Fletcher, HP | 1 |
| Gavin, JR | 1 |
1 trial available for tolazamide and Insulin Resistance
| Article | Year |
|---|---|
Effects of tolazamide and exogenous insulin on insulin action in patients with non-insulin-dependent diabetes mellitus.
Topics: Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Erythrocytes; Glycate | 1986 |
2 other studies available for tolazamide and Insulin Resistance
| Article | Year |
|---|---|
2-Deoxyglucose tissue levels and insulin levels following tolazamide dosing in normal and obese mice.
Topics: Adipose Tissue; Animals; Deoxy Sugars; Deoxyglucose; Insulin; Insulin Resistance; Male; Mice; Mice, | 1986 |
Dual actions of sulfonylureas and glyburide. Receptor and post-receptor effects.
Topics: Adipose Tissue; Animals; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mel | 1985 |