todralazine has been researched along with Blood Pressure, High in 10 studies
Todralazine: An antihypertensive agent with both central and peripheral action; it has some central nervous system depressant effects.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrochlorothiazide and binazine treatment decreased systolic and diastolic blood pressure, the total electromechanical systolic time index (QS2I) and the left ventricular ejection time index (LVETI), and increased the PEP/LVET index at rest and after exercise." | 5.27 | Post-exertion changes in left ventricular systolic time intervals in patients with primary hypertension treated with hydrochlorothiazide, binazine, and propranolol. ( Cholewa, M; Górski, L; Markiewicz, K, 1985) |
| " LD50 values were 72 mg." | 1.29 | Acute systemic toxicity and antihypertensive activity of a novel todralazine analog in rats. ( Aranjo, P; Biniecki, K; Ciszewski, L; Czyzewska-Szafran, H; Fijałek, Z; Goźlińska, B; Jastrzebski, Z; Jedrych, A; Mazurek, AP; Wutkiewicz, M, 1993) |
| "Hydrochlorothiazide and binazine treatment decreased systolic and diastolic blood pressure, the total electromechanical systolic time index (QS2I) and the left ventricular ejection time index (LVETI), and increased the PEP/LVET index at rest and after exercise." | 1.27 | Post-exertion changes in left ventricular systolic time intervals in patients with primary hypertension treated with hydrochlorothiazide, binazine, and propranolol. ( Cholewa, M; Górski, L; Markiewicz, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kolber-Postepska, B | 2 |
| Kleinrok, Z | 1 |
| Markiewicz, M | 4 |
| Cybulska, I | 1 |
| Kedrowa, S | 1 |
| Kudlicki, J | 1 |
| Jastrzebski, Z | 1 |
| Czyzewska-Szafran, H | 1 |
| Goźlińska, B | 1 |
| Wutkiewicz, M | 1 |
| Jedrych, A | 1 |
| Fijałek, Z | 1 |
| Biniecki, K | 1 |
| Aranjo, P | 1 |
| Ciszewski, L | 1 |
| Mazurek, AP | 1 |
| Dohi, Y | 1 |
| Kojima, M | 1 |
| Sato, K | 1 |
| Parravicini, F | 1 |
| Scarpitta, G | 1 |
| Dorigotti, L | 1 |
| Pifferi, G | 1 |
| Reiterer, W | 1 |
| Czitober, H | 1 |
| Markiewicz, K | 1 |
| Górski, L | 1 |
| Cholewa, M | 1 |
10 other studies available for todralazine and Blood Pressure, High
| Article | Year |
|---|---|
[Effect of various hypotensive drugs on the plasma level of kininogen and prekallikrein in hypertension].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Furosemide; Humans; Hypertension; Kallikrein | 1980 |
[Phthalazine derivatives in the treatment of arterial hypertension].
Topics: Arterioles; Blood Pressure; Humans; Hydralazine; Hydrazines; Hypertension; Todralazine; Vasodilator | 1981 |
[Hypotensive action of binazine in the light of our studies].
Topics: Adult; Aged; Female; Humans; Hydrazines; Hypertension; Hypertension, Renal; Male; Middle Aged; Todra | 1980 |
Acute systemic toxicity and antihypertensive activity of a novel todralazine analog in rats.
Topics: Animals; Blood Pressure; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Todralazine | 1993 |
Benidipine improves endothelial function in renal resistance arteries of hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropy | 1996 |
[3-Hydrazinepyridazine derivatives. III. Synthesis and anti-hypertensive activity of new 3-(2-acylhydrazine)-pyridazine-6-alkylamino substitutes].
Topics: Animals; Antihypertensive Agents; Hydralazine; Hydrazines; Hypertension; Pyridazines; Rats; Todralaz | 1979 |
[The influence of guanazodine and todralazine on blood pressure regulation during dynamic and static exercise in essential hypertension (author's transl)].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Guanidines; Heart Rate; Humans; Hydrazines; | 1977 |
[Value of simultaneous administration of propranolol, binazine and furosemide in the treatment of hypertension].
Topics: Adult; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrazines; Hypertension; Male; Middle | 1977 |
[Value of simultaneous administration of Propranolol and Binazin in the treatment of arterial hypertension].
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Male; Middle Aged; Propr | 1975 |
Post-exertion changes in left ventricular systolic time intervals in patients with primary hypertension treated with hydrochlorothiazide, binazine, and propranolol.
Topics: Adult; Aged; Female; Heart Ventricles; Humans; Hydrazines; Hydrochlorothiazide; Hypertension; Male; | 1985 |