tocainide has been researched along with Myotonia in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Camerino, DC; Carocci, A; Catalano, A; Corbo, F; De Bellis, M; De Luca, A; Franchini, C; Muraglia, M; Scilimati, A; Sinicropi, MS; Tortorella, V | 1 |
| Carbonara, R; Carratù, MR; Conte Camerino, D; Corbo, F; De Bellis, M; De Luca, A; Desaphy, JF; Farinato, A; Franchini, C; Massari, A; Muraglia, M; Pierno, S; Roussel, J | 1 |
| Dengler, R; Emser, W; Haass, A; Ricker, K; Rüdel, R | 1 |
| Courtney, KR | 1 |
| Kurihara, T; Nemoto, H | 1 |
| Conte Camerino, D; Corbo, F; De Bellis, M; De Luca, A; Desaphy, JF; Franchini, C; Jockusch, H; Lentini, G; Scilimati, A; Talon, S; Tortorella, P | 1 |
| Kwieciński, H; Ostrzycki, A; Ryniewicz, B | 1 |
| Brinkmeier, H; Jockusch, H; Mehrke, G | 1 |
| Böhlen, R; Kingston, WJ; Moxley, RT; Ricker, K | 1 |
| Bertram, K; Füchtbauer, EM; Jockusch, H; Reininghaus, J | 1 |
| Jockusch, H; Reininghaus, J; Stuhlfauth, I; Zippel, M | 1 |
| Berchtold, MW; Jockusch, H; Kluxen, FW; Schöffl, F | 1 |
| Aichele, R; Heller, AH; Paik, H | 1 |
1 review(s) available for tocainide and Myotonia
| Article | Year |
|---|---|
[Na channel myotonia].
Topics: Chromosomes, Human, Pair 7; Diagnosis, Differential; Exons; Genes, Dominant; Humans; Mexiletine; Mutation; Myotonia; Prognosis; Sodium Channel Blockers; Sodium Channels; Tocainide | 2001 |
1 trial(s) available for tocainide and Myotonia
| Article | Year |
|---|---|
Treatment of myotonia with antiarrhythmic drugs.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Female; Humans; Male; Mexiletine; Middle Aged; Myotonia; Myotonia Congenita; Myotonic Dystrophy; Neurologic Examination; Phenytoin; Prospective Studies; Single-Blind Method; Tocainide | 1992 |
11 other study(ies) available for tocainide and Myotonia
| Article | Year |
|---|---|
Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents.
Topics: Molecular Structure; Muscle, Skeletal; Myotonia; Sodium Channel Blockers; Structure-Activity Relationship; Tocainide | 2008 |
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity.
Topics: Animals; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Humans; Male; Mexiletine; Muscle, Skeletal; Myotonia; NAV1.4 Voltage-Gated Sodium Channel; Rats; Rats, Wistar; Reflex, Righting; Rotarod Performance Test; Tocainide; Voltage-Gated Sodium Channel Blockers | 2017 |
Improved therapy of myotonia with the lidocaine derivative tocainide.
Topics: Adolescent; Adult; Aged; Anilides; Anti-Arrhythmia Agents; Female; Humans; Male; Middle Aged; Myotonia; Tocainide | 1980 |
Depressant effects of drugs used in myotonia therapy.
Topics: Animals; In Vitro Techniques; Ion Channels; Lidocaine; Mexiletine; Muscle Contraction; Myotonia; Phenytoin; Procainamide; Quinidine; Rana catesbeiana; Tocainide | 1982 |
Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na(+) channels enhancing the antimyotonic activity in vivo.
Topics: Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; In Vitro Techniques; Membrane Potentials; Mice; Mice, Mutant Strains; Muscle Contraction; Muscle, Skeletal; Mutation; Myotonia; Rana esculenta; Sodium Channel Blockers; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tocainide | 2001 |
The myotonic mouse mutant ADR: electrophysiology of the muscle fiber.
Topics: Action Potentials; Animals; Chlorides; Ion Channels; Lidocaine; Mice; Mice, Neurologic Mutants; Muscle Contraction; Muscles; Myotonia; Phenotype; Tocainide | 1988 |
Potassium uptake in muscle during paramyotonic weakness.
Topics: Adult; Arteries; Cold Temperature; Exercise; Forearm; Humans; Hyperkalemia; Infant; Lidocaine; Male; Muscles; Myotonia; Paralysis; Periodicity; Potassium; Tocainide; Veins | 1989 |
The myotonic mouse mutant ADR: physiological and histochemical properties of muscle.
Topics: Adenosine Triphosphatases; Animals; Electromyography; Glycerolphosphate Dehydrogenase; Lidocaine; Mice; Mice, Neurologic Mutants; Muscle Contraction; Muscles; Myotonia; Phenotype; Succinate Dehydrogenase; Tocainide | 1988 |
Reduction of myosin-light-chain phosphorylation and of parvalbumin content in myotonic mouse muscle and its reversal by tocainide.
Topics: Animals; Lidocaine; Mice; Mice, Mutant Strains; Muscle Contraction; Muscle Proteins; Muscles; Myosins; Myotonia; Parvalbumins; Phosphoproteins; Phosphorylation; Tocainide | 1988 |
Opposite regulation of the mRNAs for parvalbumin and p19/6.8 in myotonic mouse muscle.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Immunochemistry; Lidocaine; Mice; Mice, Mutant Strains; Muscle Proteins; Muscles; Myotonia; Nucleic Acid Hybridization; Parvalbumins; Protein Biosynthesis; RNA, Messenger; Tocainide | 1988 |
Efficacy of phenytoin, procainamide, and tocainide in murine genetic myotonia.
Topics: Animals; Lidocaine; Mice; Mice, Mutant Strains; Myotonia; Phenytoin; Procainamide; Tocainide | 1985 |