Page last updated: 2024-08-23

tobramycin and Ventilator-Associated Pneumonia

tobramycin has been researched along with Ventilator-Associated Pneumonia in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (36.84)29.6817
2010's7 (36.84)24.3611
2020's5 (26.32)2.80

Authors

AuthorsStudies
Dumas, JL; Köhler, T; Reinhardt, A; Ricou, B; Rohner, P; van Delden, C; Wood, P1
Abbasi, S; Ataei, B; Hakamifard, A; Homayouni, A; Khorvash, F; Torfeh Esfahani, AA1
Dhand, R1
Akbari, N; Angermair, S; Asgarpur, G; Deja, M; Grehn, C; Schwarz, C; Spies, C; Thronicke, A; Treskatsch, S; Uhrig, A1
Ataei, B; Farsaei, S; Gudarzi, M; Hakamifard, A; Khorvash, F; Mohajeri, F; Yaghoubi, S1
Gommers, D; Hoek, R; Karami, M; Stokker, J; van der Eerden, M1
Hirosako, S; Kamohara, H; Kinoshita, Y; Kohrogi, H; Migiyama, E; Migiyama, Y; Sagishima, K; Tashiro, T; Tokunaga, K1
Confreda, K; LaPlante, K; Shurko, J; Tarquinio, K1
Farrell, DJ; Jones, RN; Rhomberg, PR; Sader, HS1
Eagye, KJ; Kuti, JL; Nicasio, AM; Nicolau, DP; Palter, M; Pepe, J; Shore, E1
Boucher, BA; Croce, MA; Czosnowski, QA; Fabian, TC; Magnotti, LJ; Swanson, JM; Wood, GC1
Cox, JC; Drachman, DA; Hibbard, ML; Kopelman, TR; Maly, TJ; Matthews, MR; O'Neill, PJ; Quan, AN; Vail, SJ1
Arnold, HM; Kollef, MH; Sawyer, AM1
Moore, ME; Mueller, EW1
Cooper, A; Joshi, M; Kassira, W; McCarthy, M; Metzler, M; Olvey, S1
Baracco, G; Cohn, SM; Crookes, B; Habib, F; Hallal, A; Manning, RJ; Namias, N; Schulman, CI1
Allaouchiche, B; Boselli, E; Breilh, D; Djabarouti, S; Gordien, JB; Guillaume, C; Rimmelé, T; Saux, MC; Xuereb, F1
Dahyot-Fizelier, C; Mimoz, O1
Bulut, T; Dongelmans, DA; Korevaar, JC; Schultz, MJ; Spronk, PE; Veelo, DP1

Trials

7 trial(s) available for tobramycin and Ventilator-Associated Pneumonia

ArticleYear
Comparing inhaled colistin with inhaled fosfomycin/tobramycin as an adjunctive treatment for ventilator-associated pneumonia: An open-label randomized controlled trial.
    The clinical respiratory journal, 2023, Volume: 17, Issue:4

    Topics: Administration, Inhalation; Anti-Bacterial Agents; Colistin; Fosfomycin; Humans; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Tobramycin; Treatment Outcome

2023
A prospective phase IIA multicenter double-blinded randomized placebo-controlled clinical trial evaluating the efficacy and safety of inhaled Tobramycin in patients with ventilator-associated pneumonia (iToVAP).
    Anaesthesia, critical care & pain medicine, 2023, Volume: 42, Issue:5

    Topics: Administration, Inhalation; Anti-Bacterial Agents; Humans; Pneumonia, Ventilator-Associated; Prospective Studies; Tobramycin; Treatment Outcome

2023
Comparison of two therapeutic approaches for the management of ventilator-associated pneumonia due to multidrug-resistant Acinetobacter: a randomized clinical trial study.
    Journal of immunoassay & immunochemistry, 2020, Volume: 41, Issue:1

    Topics: Acinetobacter; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Ventilator-Associated; Tobramycin

2020
Effect of adjunctive tobramycin inhalation versus placebo on early clinical response in the treatment of ventilator-associated pneumonia: the VAPORISE randomized-controlled trial.
    Intensive care medicine, 2020, Volume: 46, Issue:3

    Topics: Administration, Inhalation; Anti-Bacterial Agents; Double-Blind Method; Humans; Pneumonia, Ventilator-Associated; Pseudomonas Infections; Tobramycin; Treatment Outcome

2020
Comparison of piperacillin/tazobactam and imipenem/cilastatin, both in combination with tobramycin, administered every 6 h for treatment of nosocomial pneumonia.
    Respiratory medicine, 2006, Volume: 100, Issue:9

    Topics: Anti-Bacterial Agents; Cilastatin; Cross Infection; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Imipenem; Male; Middle Aged; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Protease Inhibitors; Tazobactam; Tobramycin; Treatment Outcome

2006
Aerosolized tobramycin in the treatment of ventilator-associated pneumonia: a pilot study.
    Surgical infections, 2007, Volume: 8, Issue:1

    Topics: Acinetobacter; Acinetobacter Infections; Administration, Inhalation; Adult; Aged; Anti-Bacterial Agents; APACHE; Creatinine; Double-Blind Method; Female; Hospitals, University; Humans; Injections, Intravenous; Male; Middle Aged; Multiple Organ Failure; Pilot Projects; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome

2007
Reliability of mini-bronchoalveolar lavage for the measurement of epithelial lining fluid concentrations of tobramycin in critically ill patients.
    Intensive care medicine, 2007, Volume: 33, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bronchoalveolar Lavage; Chromatography, High Pressure Liquid; Critical Illness; Female; Humans; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Pneumonia, Ventilator-Associated; Prospective Studies; Reproducibility of Results; Respiratory Mucosa; Tobramycin

2007

Other Studies

12 other study(ies) available for tobramycin and Ventilator-Associated Pneumonia

ArticleYear
Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Humans; Longitudinal Studies; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections

2007
Inhaled Tobramycin for Treatment of Ventilator-Associated Pneumonia: The Interplay of Patient, Drug, and Device.
    Respiratory care, 2022, Volume: 67, Issue:1

    Topics: Administration, Inhalation; Anti-Bacterial Agents; Humans; Patients; Pneumonia, Ventilator-Associated; Pseudomonas Infections; Tobramycin

2022
Aerosolized tobramycin for Pseudomonas aeruginosa ventilator-associated pneumonia in patients with acute respiratory distress syndrome.
    Pulmonary pharmacology & therapeutics, 2017, Volume: 45

    Topics: Administration, Inhalation; Aerosols; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cohort Studies; Female; Hospitals, University; Humans; Intensive Care Units; Male; Middle Aged; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Distress Syndrome; Retrospective Studies; Tobramycin; Treatment Outcome

2017
Activities of tobramycin and polymyxin E against Pseudomonas aeruginosa biofilm-coated medical grade endotracheal tubes.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3

    Topics: Anti-Bacterial Agents; Biofilms; Drug Therapy, Combination; Humans; Intubation, Intratracheal; Microbial Sensitivity Tests; Pneumonia, Ventilator-Associated; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin

2014
Arbekacin activity against contemporary clinical bacteria isolated from patients hospitalized with pneumonia.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6

    Topics: Amikacin; Anti-Bacterial Agents; Dibekacin; Enterobacter; Humans; Klebsiella; Microbial Sensitivity Tests; Pneumonia; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Staphylococcus aureus; Tobramycin

2015
Pharmacodynamic-based clinical pathway for empiric antibiotic choice in patients with ventilator-associated pneumonia.
    Journal of critical care, 2010, Volume: 25, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Pathways; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Observation; Pneumonia, Ventilator-Associated; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin; Treatment Outcome; Vancomycin; Young Adult

2010
Adjunctive aerosolized antibiotics for treatment of ventilator-associated pneumonia.
    Pharmacotherapy, 2009, Volume: 29, Issue:9

    Topics: Acinetobacter baumannii; Adult; Aerosols; Amikacin; Anti-Bacterial Agents; APACHE; Colistin; Critical Illness; Drug Resistance, Multiple; Female; Glasgow Coma Scale; Gram-Negative Bacteria; Humans; Male; Middle Aged; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Retrospective Studies; Tobramycin; Treatment Outcome

2009
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia.
    Surgical infections, 2010, Volume: 11, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tobramycin

2010
Use of adjunctive aerosolized antimicrobial therapy in the treatment of Pseudomonas aeruginosa and Acinetobacter baumannii ventilator-associated pneumonia.
    Respiratory care, 2012, Volume: 57, Issue:8

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Administration, Inhalation; Aerosols; Anti-Bacterial Agents; APACHE; Bronchoalveolar Lavage; Colistin; Comorbidity; Female; Humans; Male; Middle Aged; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Statistics, Nonparametric; Survival Rate; Tobramycin; Treatment Outcome

2012
Aerosolized antibiotic therapy: a forward aerial assault or forced contingency for ventilator-associated pneumonia?
    Respiratory care, 2012, Volume: 57, Issue:8

    Topics: Acinetobacter Infections; Anti-Bacterial Agents; Colistin; Female; Humans; Male; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pseudomonas Infections; Tobramycin

2012
Mini-broncho-alveolar lavage: a simple and promising method for assessment of antibiotic concentration in epithelial lining fluid.
    Intensive care medicine, 2007, Volume: 33, Issue:9

    Topics: Anti-Bacterial Agents; Bronchoalveolar Lavage; Chromatography, High Pressure Liquid; Critical Illness; Humans; Infusions, Intravenous; Intensive Care Units; Pneumonia, Ventilator-Associated; Respiratory Mucosa; Tobramycin

2007
The incidence and microbial spectrum of ventilator-associated pneumonia after tracheotomy in a selective decontamination of the digestive tract-setting.
    The Journal of infection, 2008, Volume: 56, Issue:1

    Topics: Administration, Buccal; Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colistin; Critical Illness; Cross Infection; Decontamination; Enteral Nutrition; Female; Gastrointestinal Tract; Humans; Incidence; Intensive Care Units; Male; Methicillin; Microbial Sensitivity Tests; Middle Aged; Netherlands; Pneumonia, Ventilator-Associated; Retrospective Studies; Risk Factors; Staphylococcus aureus; Tobramycin; Tracheotomy

2008