Page last updated: 2024-08-23

tobramycin and Osteomyelitis

tobramycin has been researched along with Osteomyelitis in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (27.63)	18.7374
1990's	15 (19.74)	18.2507
2000's	20 (26.32)	29.6817
2010's	16 (21.05)	24.3611
2020's	4 (5.26)	2.80

Authors

Authors	Studies
Li, M; Ni, H; Qi, B; Shi, X; Wang, T; Wei, M; Wu, Y; Xu, Y; Zhang, C	1
Gu, H; Tong, K; Wei, J; Zhou, S	1
Ahmed, S; Naik, P; Qamar, N; Richards, E	1
Chisena, E; Jortani, SA; Korte, EA; Lindner, JR; Seligson, D	1
Karr, JC	1
Brizzi, BN; Fernández Alonso, C; González Del Castillo, J; Nieto Sánchez, A	1
Alberghina, F; Andreacchio, A; Canavese, F; Cravino, M; De Rosa, V; Paonessa, M	2
Castellazzi, ML; Claut, LE; Colombo, C; Daccò, V; Esposito, S	1
Abba, Y; Karunanidhi, A; Lulu, GA; Mohamad Yusof, L; Mohd Fauzi, F; Othman, F	1
Shekhar, C	1
Agrawal, S; Kumar, P; Rajnish, RK; Sudesh, P	1
Dong, Y; Shen, L; Shou, D; Wu, R; Zhang, C; Zhang, Y; Zhu, Y	1
Walsh, TP; Yates, BJ	1
Atkins, BL; Dudareva, M; Ferguson, JY; McNally, MA; Riley, ND; Stubbs, D	1
Bode-Böger, SM; Kirchner, R; Knobloch, JK; Krajewski, J; Martens-Lobenhoffer, J; Mittelstädt, H; Mulrooney, T; Russlies, M; Tröger, U	1
Cheng, Z; Wu, G; Wu, W; Ye, C; Zheng, Q	1
Conway, JD; Thonse, R	1
Dagum, AB; Khan, SU; Lau, KN; Park, DJ	1
Ramanujam, CL; Zgonis, T	1
Li-Bland, EA; McKee, MD; Schemitsch, EH; Wild, LM	1
Archdeacon, MT; Foad, M; Kazemi, N	1
McLaren, SG; Nelson, CL; Olsen, KM; Skinner, RA; Smeltzer, MS; Thomas, JR	1
Hanssen, AD; Khaliq, Y; Osmon, DR; Patel, R; Perry, AC; Piper, KE; Rouse, MS; Steckelberg, JM	1
Calhoun, JH; Lathrop, JT; Mader, JT; Ruble, R; Stevens, CM; Stevens, JH	1
Brebach, GT; Gitelis, S	1
Anglen, J; Day, D; Huyette, D; Rutledge, B	1
Anderson, RB; Bibbo, C; Davis, WH; Lee, S	1
Ambrose, CG; Clyburn, TA; Gogola, GR; Mikos, AG; Peng, AS; Raymond, AK	1
Ambrose, CG; Clyburn, TA; Gogola, GR; Gulati, P; Joseph, J; Louden, K; Mikos, AG; Wright, J	1
Abdullah, A; DiCicco, M; Goldfinger, A; Guirand, F; Jansen, SA	1
Chye, PC; Gitelis, S; Hall, DJ; Segreti, J; Turner, TM; Urban, RM	1
Bice, TG; Brooks, DE; DeJong, ES; Lonergan, KT; Thomas, DB; Wenke, JC	1
Alvarez, FG; Amorena, B; García-Alvarez, F; García-Alvarez, I; Grasa, JM; Laclériga, A; Monzón, M; Navarro-Zorraquino, M	1
Boulton, AJ; Bowling, FL; Salgami, EV; Whitehouse, RW	1
Chang, W; Colangeli, M; Colangeli, S; Di Bella, C; Donati, D; Gozzi, E	1
Moye, RA; Nisly, SA; Ray, SM	1
Horváth, A; Kubatov, M; Laky, R	1
Higham, M	1
Petri, WH; Schaberg, SJ	1
Kinberg, P	1
Kocsis, B; Kubatov, M; Laky, R; Szittyai, B	1
Norden, CW; Shaffer, MA	1
Marklein, G; Reichertz, C; Waschkowski, G	1
Henry, SL; Ostermann, PA; Seligson, D	5
Chisholm, BB; Lew, D; Sadasivan, K	1
Bramlage, LR; Embertson, RM; Holcombe, SJ; Schneider, RK	1
Hudson, MC; Murakami, H; Murakami, T; Nousiainen, MT; Ramp, WK	1
Barbaglio, A; Cortelazzi, R; Martignoni, G; Nocini, PF	1
Greene, N; Holtom, PD; McPherson, EJ; Patzakis, MJ; Ressler, RL; Shepherd, L; Warren, CA	1
Amorena, B; Gracia, E; Laclériga, A; Leiva, J; Monzón, M; Oteiza, C	1
Dumbleton, JH; Higham, PA; Scott, CP	1
Amorena, B; García-Alvarez, F; Gracia, E; Laclériga, A; Leiva, J; Monzón, M; Oteiza, C	1
Anglen, JO; Burd, TA; Day, D; Hendricks, KJ; Lane, D; Lowry, KJ; Phaup, JG	1
Dhert, WJ; Fleer, A; Hardus, K; Nijhof, MW; Schouls, LM; Verbout, AJ; Vogely, HC	1
Ferlic, RM; Petersen, RJ; Smith, PW	1
Ratschow, R	1
Fiala, M; Mandal, AK; Oparah, SS; Thadepalli, H	1
Dierks, EJ; Potter, BE	1
Dash, AK; Suryanarayanan, R	1
Ekkernkamp, A; Henry, SL; Ostermann, PA; Seligson, D	1
Petri, WH	1
Maale, GE; Meyerhoff, WL; Roland, PS; Yellin, W	1
Norden, CW; Shinners, E	1
Adams, KR; Cierny, G; Mader, JT; Wilson, KJ	1
Behrens, F; Rotschafer, JC; Scott, DM	1
Breit, R; Nade, S	1
Gustilo, RB; Merkow, RL; Tsukayama, DT	1
Mader, JT; Sheftel, TG	1
Becker, A; Burdge, RE; Ellington, LL; Greenberg, RN; Perry, CR; Vossen, MK	1
Tomczak, RL	1
Cierny, G; Mader, JT; Pennick, JJ; Sheftel, TG	1

Reviews

2 review(s) available for tobramycin and Osteomyelitis

Article	Year
Antibiotic-loaded calcium sulfate in clinical treatment of chronic osteomyelitis: a systematic review and meta-analysis. Journal of orthopaedic surgery and research, 2022, Feb-19, Volume: 17, Issue:1 Topics: Anti-Bacterial Agents; Calcium Sulfate; Gentamicins; Humans; Incidence; Osteomyelitis; Postoperative Complications; Tobramycin; Vancomycin	2022
[Antibiotics combination cefradin-tobramycin for the treatment of severe infections in trauma surgery]. Die Medizinische Welt, 1979, Nov-09, Volume: 30, Issue:45 Topics: Anti-Bacterial Agents; Burns; Cephalosporins; Cephradine; Drug Resistance, Microbial; Drug Therapy, Combination; Emergency Medical Services; Fractures, Open; Humans; Infections; Osteomyelitis; Pneumonia; Surgical Wound Infection; Tobramycin; Urinary Tract Infections	1979

Article

Year

Antibiotic-loaded calcium sulfate in clinical treatment of chronic osteomyelitis: a systematic review and meta-analysis.

Journal of orthopaedic surgery and research, 2022, Feb-19, Volume: 17, Issue:1

Topics: Anti-Bacterial Agents; Calcium Sulfate; Gentamicins; Humans; Incidence; Osteomyelitis; Postoperative Complications; Tobramycin; Vancomycin

2022

[Antibiotics combination cefradin-tobramycin for the treatment of severe infections in trauma surgery].

Die Medizinische Welt, 1979, Nov-09, Volume: 30, Issue:45

Topics: Anti-Bacterial Agents; Burns; Cephalosporins; Cephradine; Drug Resistance, Microbial; Drug Therapy, Combination; Emergency Medical Services; Fractures, Open; Humans; Infections; Osteomyelitis; Pneumonia; Surgical Wound Infection; Tobramycin; Urinary Tract Infections

1979

Trials

2 trial(s) available for tobramycin and Osteomyelitis

Article	Year
A prospective, randomized clinical trial comparing an antibiotic-impregnated bioabsorbable bone substitute with standard antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis and infected nonunion. Journal of orthopaedic trauma, 2010, Volume: 24, Issue:8 Topics: Absorption; Adult; Aged; Anti-Bacterial Agents; Bone Cements; Bone Substitutes; Chronic Disease; Drug Implants; Female; Fractures, Ununited; Humans; Male; Middle Aged; Osteomyelitis; Prospective Studies; Tobramycin; Treatment Outcome; Young Adult	2010
Randomized evaluation of ceftazidime or ticarcillin and tobramycin for the treatment of osteomyelitis caused by gram-negative bacilli. Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:1 Topics: Adolescent; Adult; Ceftazidime; Clinical Trials as Topic; Female; Gram-Negative Bacteria; Humans; Male; Osteomyelitis; Penicillins; Random Allocation; Ticarcillin; Tobramycin	1986

Article

Year

A prospective, randomized clinical trial comparing an antibiotic-impregnated bioabsorbable bone substitute with standard antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis and infected nonunion.

Journal of orthopaedic trauma, 2010, Volume: 24, Issue:8

Topics: Absorption; Adult; Aged; Anti-Bacterial Agents; Bone Cements; Bone Substitutes; Chronic Disease; Drug Implants; Female; Fractures, Ununited; Humans; Male; Middle Aged; Osteomyelitis; Prospective Studies; Tobramycin; Treatment Outcome; Young Adult

2010

Randomized evaluation of ceftazidime or ticarcillin and tobramycin for the treatment of osteomyelitis caused by gram-negative bacilli.

Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:1

Topics: Adolescent; Adult; Ceftazidime; Clinical Trials as Topic; Female; Gram-Negative Bacteria; Humans; Male; Osteomyelitis; Penicillins; Random Allocation; Ticarcillin; Tobramycin

1986

Other Studies

72 other study(ies) available for tobramycin and Osteomyelitis

Article	Year
Meropenem-loaded Cement Is Effective in Preventing Gram-negative Osteomyelitis in an Animal Model. Clinical orthopaedics and related research, 2023, 01-01, Volume: 481, Issue:1 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bone Cements; Ceftazidime; Ciprofloxacin; Escherichia coli; Male; Meropenem; Microbial Sensitivity Tests; Models, Animal; Osteomyelitis; Piperacillin; Rats; Tobramycin	2023
Use of tobramycin-impregnated antibiotic beads in frontal sinus osteomyelitis. The Journal of laryngology and otology, 2023, Volume: 137, Issue:8 Topics: Anti-Bacterial Agents; Frontal Sinus; Humans; Osteomyelitis; Tobramycin	2023
Does an antibiotic nail made in a lubricated tube release antibiotic? European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2020, Volume: 30, Issue:1 Topics: Bone Nails; Case-Control Studies; Coated Materials, Biocompatible; Drug Delivery Systems; Femoral Fractures; Fracture Fixation, Intramedullary; Fractures, Open; Humans; Kentucky; Mineral Oil; Osteomyelitis; Reference Values; Sampling Studies; Sensitivity and Specificity; Surgical Wound Infection; Tibial Fractures; Tobramycin	2020
An Overview of the Percutaneous Antibiotic Delivery Technique for Osteomyelitis Treatment and a Case Study of Calcaneal Osteomyelitis. Journal of the American Podiatric Medical Association, 2017, Volume: 107, Issue:6 Topics: Anti-Bacterial Agents; Calcaneus; Female; Humans; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Osteomyelitis; Staphylococcal Infections; Tobramycin; Vancomycin	2017
[Vertebral osteomyelitis due to Actinomyces: a case report]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2018, Volume: 31, Issue:1 Topics: Actinomycosis; Aged; Anti-Bacterial Agents; Ceftriaxone; Humans; Male; Osteomyelitis; Tobramycin	2018
Tobramycin-impregnated calcium sulfate pellets for the treatment of chronic osteomyelitis in children and adolescents. Journal of pediatric orthopedics. Part B, 2019, Volume: 28, Issue:3 Topics: Adolescent; Anti-Bacterial Agents; Calcium Sulfate; Child; Child, Preschool; Chronic Disease; Drug Implants; Female; Follow-Up Studies; Humans; Male; Osteomyelitis; Retrospective Studies; Tobramycin; Treatment Outcome	2019
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in two young children: the importance of an early diagnosis. Italian journal of pediatrics, 2018, Aug-15, Volume: 44, Issue:1 Topics: Child, Preschool; Drug Hypersensitivity Syndrome; Drug Therapy, Combination; Early Diagnosis; Eosinophilia; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Osteomyelitis; Piperacillin; Pneumonia, Bacterial; Risk Assessment; Sampling Studies; Tobramycin; Vancomycin; Withholding Treatment	2018
In vivo efficacy of tobramycin-loaded synthetic calcium phosphate beads in a rabbit model of staphylococcal osteomyelitis. Annals of clinical microbiology and antimicrobials, 2018, Dec-28, Volume: 17, Issue:1 Topics: Animals; Anti-Bacterial Agents; Calcium Phosphates; Disease Models, Animal; Drug Delivery Systems; Humans; Male; Osteomyelitis; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tobramycin	2018
An Innovative Technique in Local Antibiotic Delivery Method in Open Infected Wounds of the Musculoskeletal System. The international journal of lower extremity wounds, 2019, Volume: 18, Issue:2 Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Cholecalciferol; Cohort Studies; Drug Carriers; Female; Fractures, Open; Humans; Male; Middle Aged; Osteomyelitis; Prognosis; Retrospective Studies; Risk Assessment; Severity of Illness Index; Soft Tissue Infections; Staphylococcal Infections; Tobramycin; Vancomycin; Wound Healing; Wound Infection	2019
Tobramycin-impregnated calcium sulfate pellets for the treatment of chronic osteomyelitis in children and adolescents: is the rationale of antibiotics use appropriate? Journal of pediatric orthopedics. Part B, 2019, Volume: 28, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Calcium; Calcium Sulfate; Child; Humans; Osteomyelitis; Tobramycin	2019
Response to 'Tobramycin-impregnated calcium sulfate pellets for the treatment of chronic osteomyelitis in children and adolescents: is the rationale of antibiotics use appropriate?' by Rajnish et al. Journal of pediatric orthopedics. Part B, 2019, Volume: 28, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Calcium; Calcium Sulfate; Child; Humans; Osteomyelitis; Tobramycin	2019
Rapid quantification of tobramycin and vancomycin by UPLC-TQD and application to osteomyelitis patient samples. Journal of chromatographic science, 2014, Volume: 52, Issue:6 Topics: Chromatography, High Pressure Liquid; Humans; Osteomyelitis; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tobramycin; Vancomycin	2014
Calcanectomy: avoiding major amputation in the presence of calcaneal osteomyelitis-A case series. Foot (Edinburgh, Scotland), 2013, Volume: 23, Issue:4 Topics: Aged; Aged, 80 and over; Amputation, Surgical; Anti-Bacterial Agents; Calcaneus; Calcium Sulfate; Debridement; Diabetic Foot; Gentamicins; Hemostatics; Humans; Length of Stay; Limb Salvage; Middle Aged; Osteomyelitis; Retrospective Studies; Tendons; Tobramycin; Wound Healing	2013
The use of a biodegradable antibiotic-loaded calcium sulphate carrier containing tobramycin for the treatment of chronic osteomyelitis: a series of 195 cases. The bone & joint journal, 2014, Volume: 96-B, Issue:6 Topics: Absorbable Implants; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Calcium Sulfate; Chronic Disease; Cohort Studies; Debridement; Drug Carriers; Female; Follow-Up Studies; Humans; Intraoperative Care; Kaplan-Meier Estimate; Male; Middle Aged; Osteomyelitis; Prospective Studies; Severity of Illness Index; Statistics, Nonparametric; Tobramycin; Treatment Outcome; Wound Healing	2014
Successful treatment of extensively drug-resistant Pseudomonas aeruginosa osteomyelitis using a colistin- and tobramycin-impregnated PMMA spacer. International journal of antimicrobial agents, 2014, Volume: 44, Issue:4 Topics: Anti-Bacterial Agents; Colistin; Drug Carriers; Drug Resistance, Multiple, Bacterial; Humans; Male; Middle Aged; Osteomyelitis; Plasma; Polymethyl Methacrylate; Pseudomonas aeruginosa; Pseudomonas Infections; Synovial Fluid; Tobramycin; Treatment Outcome	2014
A therapeutic delivery system for chronic osteomyelitis via a multi-drug implant based on three-dimensional printing technology. Journal of biomaterials applications, 2016, Volume: 31, Issue:2 Topics: Animals; Drug Delivery Systems; Drug Implants; Drug Liberation; Levofloxacin; Male; Osteomyelitis; Polyesters; Printing, Three-Dimensional; Rabbits; Tobramycin	2016
Antibiotic cement-coated nails for the treatment of infected nonunions and segmental bone defects. The Journal of bone and joint surgery. American volume, 2008, Volume: 90 Suppl 4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Cements; Bone Nails; Female; Fracture Fixation, Intramedullary; Fractures, Ununited; Humans; Male; Middle Aged; Osteomyelitis; Postoperative Complications; Reoperation; Retrospective Studies; Surgical Wound Infection; Tobramycin; Treatment Outcome; Vancomycin; Young Adult	2008
Antibiotic-impregnated polymethylmethacrylate beads and cement in the treatment of posttraumatic infections of the frontal sinus. Plastic and reconstructive surgery, 2009, Volume: 123, Issue:6 Topics: Bone Cements; Combined Modality Therapy; Delayed-Action Preparations; Drug Combinations; Frontal Sinus; Humans; Methylmethacrylates; Osteomyelitis; Surgical Flaps; Tobramycin; Vancomycin	2009
Antibiotic-loaded cement beads for Charcot ankle osteomyelitis. Foot & ankle specialist, 2010, Volume: 3, Issue:5 Topics: Ankle Joint; Anti-Bacterial Agents; Arthropathy, Neurogenic; Bone Cements; Diabetic Foot; Drug Implants; External Fixators; Female; Humans; Middle Aged; Osteomyelitis; Tobramycin	2010
Fellow's corner: grand rounds from the university of cincinnati medical center - chronic osteomyelitis of the tibia. Journal of orthopaedic trauma, 2011, Volume: 25, Issue:11 Topics: Adult; Anti-Bacterial Agents; Bacitracin; Bone Transplantation; Debridement; Hospitals, University; Humans; Male; Orthopedics; Osseointegration; Osteomyelitis; Teaching Rounds; Tibia; Tobramycin; Treatment Outcome	2011
The treatment of experimental osteomyelitis by surgical debridement and the implantation of calcium sulfate tobramycin pellets. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2002, Volume: 20, Issue:4 Topics: Animals; Anti-Bacterial Agents; Calcium Sulfate; Debridement; Drug Delivery Systems; Drug Implants; Osteomyelitis; Rabbits; Tobramycin	2002
Antimicrobial release kinetics from polymethylmethacrylate in a novel continuous flow chamber. Clinical orthopaedics and related research, 2002, Issue:403 Topics: Amikacin; Anti-Bacterial Agents; Drug Carriers; Drug Delivery Systems; Gentamicins; Humans; In Vitro Techniques; Models, Immunological; Osteomyelitis; Polymethyl Methacrylate; Reproducibility of Results; Time Factors; Tobramycin; Vancomycin; Vasodilator Agents	2002
Treatment of experimental osteomyelitis with a fibrin sealant antibiotic implant. Clinical orthopaedics and related research, 2002, Issue:403 Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Implants; Female; Fibrin Tissue Adhesive; Microbial Sensitivity Tests; Osteomyelitis; Polymethyl Methacrylate; Rabbits; Tissue Adhesives; Tobramycin; Vasodilator Agents	2002
The treatment of chronic osteomyelitis with a biodegradable antibiotic-impregnated implant. Journal of orthopaedic surgery (Hong Kong), 2002, Volume: 10, Issue:1 Topics: Absorbable Implants; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Calcium Sulfate; Chronic Disease; Drug Delivery Systems; Drug Implants; Female; Humans; Male; Middle Aged; Osteomyelitis; Tobramycin; Treatment Outcome; Vancomycin	2002
Treatment of osteomyelitis with local antibiotics delivered via bioabsorbable polymer. Clinical orthopaedics and related research, 2003, Issue:411 Topics: Absorbable Implants; Animals; Anti-Bacterial Agents; Chi-Square Distribution; Drug Implants; Osteomyelitis; Polyesters; Polymethyl Methacrylate; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tobramycin	2003
Limb salvage: the infected retrograde tibiotalocalcaneal intramedullary nail. Foot & ankle international, 2003, Volume: 24, Issue:5 Topics: Adult; Aged; Anti-Bacterial Agents; Arthrodesis; Bone Nails; Drug Delivery Systems; Female; Humans; Immunocompromised Host; Leg; Male; Middle Aged; Osteomyelitis; Prospective Studies; Reoperation; Salvage Therapy; Tobramycin; Vancomycin	2003
Antibiotic microspheres: preliminary testing for potential treatment of osteomyelitis. Clinical orthopaedics and related research, 2003, Issue:415 Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Evaluation, Preclinical; Female; Fluorescence Polarization Immunoassay; Inflammation; Mice; Mice, Inbred ICR; Microspheres; Molecular Weight; Muscle, Skeletal; Osteomyelitis; Polyethylene Glycols; Polyglactin 910; Tobramycin	2003
Effective treatment of osteomyelitis with biodegradable microspheres in a rabbit model. Clinical orthopaedics and related research, 2004, Issue:421 Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Cefazolin; Disease Models, Animal; Drug Carriers; Infusions, Parenteral; Lactic Acid; Male; Microspheres; Osteomyelitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polymethyl Methacrylate; Rabbits; Radiography; Radius; Staphylococcal Infections; Tobramycin	2004
In vitro tobramycin elution analysis from a novel beta-tricalcium phosphate-silicate-xerogel biodegradable drug-delivery system. Journal of biomedical materials research. Part B, Applied biomaterials, 2004, Jul-15, Volume: 70, Issue:1 Topics: Anti-Bacterial Agents; Benzoates; Biocompatible Materials; Bone Substitutes; Calcium Carbonate; Calcium Phosphates; Drug Delivery Systems; Gels; Humans; Hydroxyapatites; Materials Testing; Molecular Structure; Osteomyelitis; Quinolines; Reproducibility of Results; Silicates; Tobramycin	2004
Local and systemic levels of tobramycin delivered from calcium sulfate bone graft substitute pellets. Clinical orthopaedics and related research, 2005, Issue:437 Topics: Animals; Anti-Bacterial Agents; Bone Substitutes; Bone Transplantation; Calcium Sulfate; Dogs; Dose-Response Relationship, Drug; Drug Implants; Follow-Up Studies; Humerus; Male; Osteomyelitis; Radiography; Tobramycin	2005
Tobramycin-impregnated calcium sulfate prevents infection in contaminated wounds. Clinical orthopaedics and related research, 2005, Volume: 441 Topics: Animals; Anti-Bacterial Agents; Bone Substitutes; Calcium Sulfate; Drug Delivery Systems; Fractures, Open; Goats; Male; Osteomyelitis; Radiography; Staphylococcal Infections; Tobramycin	2005
Interleukin-1, interleukin-6, and interleukin-10 responses after antibiotic treatment in experimental chronic Staphylococcus aureus osteomyelitis. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2006, Volume: 11, Issue:4 Topics: Animals; Anti-Bacterial Agents; Biofilms; Cefuroxime; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Interleukin-1; Interleukin-10; Interleukin-6; Interleukins; Male; Osteomyelitis; Rats; Rats, Wistar; Staphylococcal Infections; Tibia; Tobramycin; Vancomycin	2006
Use of tobramycin-impregnated calcium sulphate pellets in addition to oral antibiotics: an alternative treatment to minor amputation in a case of diabetic foot osteomyelitis. Diabetes care, 2007, Volume: 30, Issue:1 Topics: Administration, Oral; Administration, Topical; Amputation, Surgical; Bacterial Infections; Diabetic Foot; Humans; Osteomyelitis; Postoperative Complications; Tobramycin	2007
Adult osteomyelitis: debridement versus debridement plus Osteoset T pellets. Acta orthopaedica Belgica, 2007, Volume: 73, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Calcium Sulfate; Debridement; Drug Delivery Systems; Female; Humans; Male; Middle Aged; Osteomyelitis; Radiography; Retrospective Studies; Staphylococcal Infections; Tobramycin	2007
Tobramycin-induced hepatotoxicity. The Annals of pharmacotherapy, 2007, Volume: 41, Issue:12 Topics: Adult; Anti-Bacterial Agents; Bacteremia; Chemical and Drug Induced Liver Injury; Female; Humans; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2007
[Treatment of experimental osteomyelitis with polymethyl methacrylate pellets containing tobramycin or cephalothin]. Magyar traumatologia, orthopaedia es helyreallito sebeszet, 1982, Volume: 25, Issue:4 Topics: Animals; Anti-Bacterial Agents; Cephalothin; Drug Implants; Osteomyelitis; Polymethacrylic Acids; Rabbits; Tobramycin	1982
Infection in a puncture wound after it 'healed'. Hospital practice (Office ed.), 1983, Volume: 18, Issue:4 Topics: Child; Foot Injuries; Humans; Male; Osteomyelitis; Pseudomonas Infections; Ticarcillin; Tobramycin; Wound Infection; Wounds, Penetrating	1983
The effects of antibiotic-supplemented bone allografts on contaminated, partially avulsive fractures of the canine ulna. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1984, Volume: 42, Issue:11 Topics: Animals; Bone Transplantation; Cephalothin; Dogs; Male; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Staphylococcus aureus; Tissue Preservation; Tobramycin; Ulna; Ulna Fractures; Wound Healing	1984
Osteomyelitis of an epiphyseal region. The Journal of foot surgery, 1983,Fall, Volume: 22, Issue:3 Topics: Adolescent; Drainage; Drug Therapy, Combination; Follow-Up Studies; Foot Diseases; Humans; Length of Stay; Male; Nafcillin; Osteomyelitis; Pseudomonas Infections; Staphylococcal Infections; Staphylococcus aureus; Ticarcillin; Time Factors; Tobramycin; Toes	1983
[Model studies of the antibiotic release of gentamycin, tobramycin and cephalothin polymethylmethacrylate beads in vivo]. Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1983, Volume: 16, Issue:5 Topics: Animals; Bone and Bones; Cephalothin; Drug Implants; Gentamicins; Methylmethacrylates; Osteomyelitis; Rabbits; Tibia; Tobramycin	1983
Activities of tobramycin and azlocillin alone and in combination against experimental osteomyelitis caused by Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:1 Topics: Animals; Anti-Bacterial Agents; Azlocillin; Drug Therapy, Combination; Osteomyelitis; Penicillins; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Tobramycin	1982
[Septicaemia caused by Erwinia herbicola in an 8-year-old boy (author's transl)]. Klinische Padiatrie, 1981, Volume: 193, Issue:5 Topics: Carbenicillin; Cephalothin; Child; Erwinia; Humans; Male; Osteomyelitis; Sepsis; Tobramycin	1981
Local antibiotic therapy for severe open fractures. A review of 1085 consecutive cases. The Journal of bone and joint surgery. British volume, 1995, Volume: 77, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefazolin; Chronic Disease; Drug Therapy, Combination; Extremities; Female; Fractures, Open; Humans; Male; Methylmethacrylates; Middle Aged; Osteomyelitis; Penicillins; Retrospective Studies; Tobramycin; Wound Infection	1995
The role of local antibiotic therapy in the management of compound fractures. Clinical orthopaedics and related research, 1993, Issue:295 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Drug Delivery Systems; Drug Therapy, Combination; Female; Fractures, Open; Humans; Male; Middle Aged; Osteomyelitis; Retrospective Studies; Tobramycin; Wound Infection	1993
The antibiotic bead pouch technique. The management of severe compound fractures. Clinical orthopaedics and related research, 1993, Issue:295 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Delivery Systems; Drug Therapy, Combination; Female; Fractures, Open; Humans; Male; Middle Aged; Osteomyelitis; Retrospective Studies; Tobramycin; Wound Infection	1993
[Value of adjuvant local antibiotic administration in therapy of open fractures. A comparative analysis of 704 consecutive cases]. Langenbecks Archiv fur Chirurgie, 1993, Volume: 378, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Implants; External Fixators; Female; Fracture Healing; Fractures, Open; Humans; Male; Methylmethacrylates; Middle Aged; Osteomyelitis; Retrospective Studies; Tobramycin	1993
The use of tobramycin-impregnated polymethylmethacrylate beads in the treatment of osteomyelitis of the mandible: report of three cases. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1993, Volume: 51, Issue:4 Topics: Adult; Drug Implants; Female; Humans; Male; Mandibular Diseases; Methylmethacrylates; Osteomyelitis; Tobramycin	1993
Use of antibiotic-impregnated polymethyl methacrylate in horses with open or infected fractures or joints: 19 cases (1987-1995). Journal of the American Veterinary Medical Association, 1997, Oct-01, Volume: 211, Issue:7 Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefazolin; Combined Modality Therapy; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Fracture Fixation, Internal; Fractures, Open; Gentamicins; Horse Diseases; Horses; Joint Diseases; Joints; Osteomyelitis; Polymethyl Methacrylate; Retrospective Studies; Synovitis; Tobramycin	1997
Calcium hydroxide ameliorates tobramycin toxicity in cultured chick tibiae. Bone, 1997, Volume: 21, Issue:5 Topics: Animals; Anti-Bacterial Agents; Calcium; Calcium Hydroxide; Chick Embryo; Culture Media; Drug Carriers; Hydrogen-Ion Concentration; Organ Culture Techniques; Osteomyelitis; Polymethyl Methacrylate; Staphylococcus aureus; Tibia; Tobramycin	1997
Osteopetrosis complicated by osteomyelitis of the mandible: a case report including gross and microscopic findings. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1998, Volume: 56, Issue:3 Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Disease Susceptibility; Humans; Male; Mandible; Mandibular Diseases; Osteomyelitis; Osteopetrosis; Recurrence; Tobramycin	1998
In vitro elution of tobramycin and vancomycin polymethylmethacrylate beads and spacers from Simplex and Palacos. American journal of orthopedics (Belle Mead, N.J.), 1998, Volume: 27, Issue:3 Topics: Anti-Bacterial Agents; Bone Cements; Humans; Methylmethacrylates; Orthopedic Equipment; Osteomyelitis; Polymethyl Methacrylate; Polystyrenes; Prostheses and Implants; Tobramycin; Vancomycin	1998
Application of a rat osteomyelitis model to compare in vivo and in vitro the antibiotic efficacy against bacteria with high capacity to form biofilms. The Journal of surgical research, 1998, Volume: 79, Issue:2 Topics: Animals; Anti-Bacterial Agents; Biofilms; Cefuroxime; Cephalosporins; Male; Microbial Sensitivity Tests; Osteomyelitis; Predictive Value of Tests; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Tobramycin; Vancomycin	1998
Effectiveness of bone cement containing tobramycin. An in vitro susceptibility study of 99 organisms found in infected joint arthroplasty. The Journal of bone and joint surgery. British volume, 1999, Volume: 81, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Infections; Bone Cements; Dose-Response Relationship, Drug; Drug Stability; Humans; Methylmethacrylate; Microbial Sensitivity Tests; Osteomyelitis; Surgical Wound Infection; Tobramycin	1999
A simple infection model using pre-colonized implants to reproduce rat chronic Staphylococcus aureus osteomyelitis and study antibiotic treatment. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2001, Volume: 19, Issue:5 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Cefuroxime; Cephalosporins; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Male; Osteomyelitis; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Tibia; Tobramycin; Vancomycin	2001
Elution characteristics of tobramycin from polycaprolactone in a rabbit model. Clinical orthopaedics and related research, 2001, Issue:392 Topics: Animals; Biodegradation, Environmental; Drug Delivery Systems; Male; Models, Animal; Osteomyelitis; Polyesters; Rabbits; Tobramycin	2001
Tobramycin-containing bone cement and systemic cefazolin in a one-stage revision. Treatment of infection in a rabbit model. Journal of biomedical materials research, 2001, Volume: 58, Issue:6 Topics: Animals; Arthroplasty, Replacement; Bone Cements; Bone Marrow; Cefazolin; Debridement; DNA, Bacterial; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Implants, Experimental; Injections; Injections, Subcutaneous; Joint Prosthesis; Models, Animal; Osteomyelitis; Prosthesis-Related Infections; Rabbits; Radiography; Reoperation; Staphylococcal Infections; Staphylococcus aureus; Surgical Wound Infection; Tibia; Tobramycin	2001
Gallium scan in sternal osteomyelitis. AJR. American journal of roentgenology, 1979, Volume: 132, Issue:5 Topics: Carbenicillin; Gallium Radioisotopes; Gentamicins; Humans; Injections, Intravenous; Male; Middle Aged; Osteomyelitis; Radionuclide Imaging; Sternum; Thoracic Diseases; Tobramycin	1979
Osteolytic lesion indicating Pseudomonas sternal osteomyelitis. Archives of surgery (Chicago, Ill. : 1960), 1976, Volume: 111, Issue:7 Topics: Accidents, Traffic; Adult; Heroin Dependence; Humans; Male; Middle Aged; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Sternum; Tobramycin	1976
Treatment of an infected mandibular graft using tobramycin-impregnated methylmethacrylate beads: report of a case. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1992, Volume: 50, Issue:11 Topics: Adult; Ameloblastoma; Bone Transplantation; Drug Implants; Eikenella corrodens; Gram-Negative Bacterial Infections; Humans; Male; Mandibular Neoplasms; Methylmethacrylate; Methylmethacrylates; Osteomyelitis; Reoperation; Surgical Wound Infection; Tobramycin	1992
An implantable dosage form for the treatment of bone infections. Pharmaceutical research, 1992, Volume: 9, Issue:8 Topics: Cross-Linking Reagents; Dimethylpolysiloxanes; Drug Delivery Systems; Drug Implants; Drug Stability; Glycerol; In Vitro Techniques; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Osteomyelitis; Silicones; Tobramycin	1992
[Treatment of type II B open fracture--therapeutic regimen and results]. Zentralblatt fur Chirurgie, 1992, Volume: 117, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Female; Fracture Fixation, Internal; Fracture Healing; Fractures, Open; Humans; Male; Methylmethacrylates; Middle Aged; Osteomyelitis; Tobramycin; Wound Infection	1992
Evaluation of antibiotic-supplemented bone allograft in a rabbit model. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1991, Volume: 49, Issue:4 Topics: Animals; Bone Transplantation; Cephalothin; Disease Models, Animal; Mandibular Fractures; Osteomyelitis; Prevotella melaninogenica; Rabbits; Staphylococcus aureus; Tobramycin; Transplantation, Homologous	1991
[Treatment of 2d and 3d degree complicated tibial shaft fractures with the PMMA bead pouch technic]. Der Unfallchirurg, 1989, Volume: 92, Issue:11 Topics: Adolescent; Adult; Combined Modality Therapy; Female; Fracture Fixation, Internal; Fractures, Open; Humans; Male; Methylmethacrylates; Middle Aged; Osteomyelitis; Polyurethanes; Retrospective Studies; Tibial Fractures; Tobramycin; Wound Healing	1989
Audiologic threshold monitoring of patients receiving ototoxic drugs. Preliminary report. The Annals of otology, rhinology, and laryngology, 1989, Volume: 98, Issue:12 Pt 1 Topics: Adolescent; Adult; Aged; Audiometry; Auditory Threshold; Female; Hearing Disorders; Humans; Kidney Function Tests; Male; Middle Aged; Monitoring, Physiologic; Osteomyelitis; Prospective Studies; Time Factors; Tobramycin; Vancomycin	1989
Ciprofloxacin as therapy for experimental osteomyelitis caused by Pseudomonas aeruginosa. The Journal of infectious diseases, 1985, Volume: 151, Issue:2 Topics: Animals; Anti-Bacterial Agents; Bone and Bones; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Rabbits; Tobramycin	1985
Comparative evaluation of the diffusion of tobramycin and cefotaxime out of antibiotic-impregnated polymethylmethacrylate beads. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1988, Volume: 6, Issue:2 Topics: Anti-Bacterial Agents; Cefotaxime; Diffusion; Escherichia coli; Klebsiella; Methylmethacrylates; Microbial Sensitivity Tests; Osteomyelitis; Postoperative Complications; Time Factors; Tobramycin	1988
Use of vancomycin and tobramycin polymethylmethacrylate impregnated beads in the management of chronic osteomyelitis. Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:6 Topics: Adult; Chronic Disease; Female; Fluorescent Antibody Technique; Humans; Male; Methylmethacrylates; Osteomyelitis; Spectrometry, Fluorescence; Tobramycin; Vancomycin	1988
Pseudomonas osteomyelitis of the spine. Report of a case not associated with drug abuse. The Australian and New Zealand journal of surgery, 1987, Volume: 57, Issue:11 Topics: Aged; Humans; Male; Osteomyelitis; Pseudomonas Infections; Radiography; Spondylitis; Thoracic Vertebrae; Ticarcillin; Tobramycin	1987
The use of tobramycin-impregnated polymethylmethacrylate beads in the therapy of deep bone and joint infections. Journal of orthopaedic trauma, 1987, Volume: 1, Issue:3 Topics: Bacterial Infections; Humans; Joint Diseases; Joint Prosthesis; Methylmethacrylates; Osteomyelitis; Tobramycin	1987
Antibiotic stability in an implantable pump. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1986, Volume: 4, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Clindamycin; Drug Stability; Gentamicins; Humans; Infusion Pumps; Microbial Sensitivity Tests; Netilmicin; Osteomyelitis; Tobramycin	1986
Outpatient treatment of osteomyelitis. Journal of the American Podiatric Medical Association, 1985, Volume: 75, Issue:5 Topics: Ambulatory Care; Female; Heparin; Humans; Metatarsus; Middle Aged; Osteomyelitis; Self Administration; Tobramycin	1985
Methicillin-resistant Staphylococcus aureus osteomyelitis. Clinical orthopaedics and related research, 1985, Issue:198 Topics: Adult; Combined Modality Therapy; Debridement; Drug Therapy, Combination; Female; Humans; Hyperbaric Oxygenation; Male; Methicillin; Middle Aged; Osteomyelitis; Penicillin Resistance; Staphylococcal Infections; Staphylococcus aureus; Tobramycin; Vancomycin	1985