tobramycin and Ophthalmoplegia

Injection of hyaluronic acid (HA) filler is a common aesthetic procedure. Impairment of vision, although rare, is a devastating complication of this procedure, which may not be reversible. We report on a patient who experienced visual acuity impairment and ischemic oculomotor nerve palsy after injection of HA into the nasal dorsum. In this case, clinical signs improved within 14 days of treatment. We also provide a review of the mechanism, clinical features, risk factors, and prevention and treatment strategies relating to embolization of ocular circulation after injection of HA. Vision loss is a rare but devastating complication of injection of hyaluronic acid (HA) in the face. Visual acuity seldom recovers completely. We report on a 22-year-old Asian woman who experienced obstruction of a branch of the retinal artery after injection of HA to augment her nose. The patient's visual acuity declined shortly after the procedure, and ophthalmoplegia occurred. Combination treatment was administered to restore the perfusion and oxygen supply to the retina and optic nerve. Within 14 days of rigorous treatment, the patient experienced improvement in visual acuity, extraocular movement, and visual field defects. LEVEL OF EVIDENCE 5: Risk.

Topics: Adult; Alprostadil; Arterial Occlusive Diseases; Cosmetic Techniques; Dexamethasone; Dextrans; Female; Humans; Hyaluronic Acid; Methacrylates; Nasal Cavity; Ophthalmoplegia; Oxygen; Retinal Artery; Solanaceous Alkaloids; Timolol; Tobramycin; Vision Disorders; Vitamin B 12; Young Adult

Topics: Adolescent; Dexamethasone; Drug Therapy, Combination; Eye Injuries; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Ophthalmic Solutions; Ophthalmoplegia; Recovery of Function; Severity of Illness Index; Time Factors; Tobramycin; Treatment Outcome; Visual Acuity