tobramycin has been researched along with Infections, Respiratory in 118 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (36.44) | 18.7374 |
| 1990's | 19 (16.10) | 18.2507 |
| 2000's | 20 (16.95) | 29.6817 |
| 2010's | 32 (27.12) | 24.3611 |
| 2020's | 4 (3.39) | 2.80 |
| Authors | Studies |
|---|---|
| Furuno, JP; Graffunder, E; Graves, J; Lodise, TP; Lomaestro, B; McGregor, JC; McNutt, LA; Miller, CD | 1 |
| Ding, HZ; Fu, JL; Jiang, HX; Wu, SL; Zhang, HL | 1 |
| Awad, R; Couet, W; Marchand, S; Tewes, F; Torres, BGS | 1 |
| Bergström, CAS; Friberg, LE; Kukavica-Ibrulj, I; Levesque, RC; Sou, T | 1 |
| Mellies, U; Naehrig, S; Sieder, C; Sutharsan, S; Ziegler, J | 1 |
| Dorgan, D; Fifer, RC; Flume, PA; Harruff, EE; Jain, R; Kil, J; Kim, YJM; Ortiz, MGT; Poth, EA; Shoup, AG | 1 |
| Caljon, G; Cappoen, D; Coenye, T; Cools, F; Cos, P; Delputte, P; Maes, L; Maira, BM; Martinet, W; Torfs, E; Vanhoutte, B | 1 |
| Cao, W; Debonnett, L; Greenwood, J; Hamed, K; Mastoridis, P; Nash, EF; Schwarz, C; Sommerwerck, U; Tamm, M | 1 |
| Cavallaro, G; Craparo, EF; Cusimano, MG; Giammona, G; Porsio, B; Schillaci, D | 1 |
| Bahamondez-Canas, TF; Leal, J; Smyth, HDC; Tewes, F; Zhang, H | 1 |
| Charbek, E; Rowbotham, NJ; Smith, S | 1 |
| Bjarnsholt, T; Ciofu, O; Høiby, N; Jensen, PØ; Kolpen, M; Kragh, KN; Møller, SA | 1 |
| Alkadri, J; Mostofian, F; Radhakrishnan, D; Tang, K; Thampi, N | 1 |
| Amighi, K; Pilcer, G; Rosière, R; Sebti, T; Traina, K; Vanderbist, F | 1 |
| Al-Aloul, M; Nazareth, D; Walshaw, M | 1 |
| Clark, P; Knight, H; Nolan, K | 1 |
| Goss, CH; Quon, BS; Ramsey, BW | 1 |
| Bonten, MJ; de Smet, AM; Oostdijk, EA; Wittekamp, BH | 1 |
| Antoniu, S | 1 |
| Kotsimbos, T; Langan, KM; Peleg, AY | 1 |
| Alonso, T; Ancochea, J; Cisneros, C; Garcia, J; Garcia-Castillo, E; Giron, RM; Gomez-Punter, RM; Marcos, C; Valenzuela, C; Vazquez-Espinosa, E; Zamora, E | 1 |
| Baziard, G; El Hage, S; Furiga, A; Lajoie, B; Roques, C | 1 |
| Cabot, G; Cantón, R; López-Causapé, C; Macià, MD; Moyà, B; Oliver, A; Pérez, JL; Rojo-Molinero, E; Rubio, R | 1 |
| Cohen, F; Elborn, JS; Flume, PA; Loutit, J; VanDevanter, DR | 1 |
| Bresnik, M; Clancy, JP; Derchak, PA; Flume, PA; Lewis, SA; Ramsey, BW; Retsch-Bogart, GZ; Tullis, DE | 1 |
| Beaudoin, T; Klingel, M; McDonald, N; Ratjen, F; Rizvi, L; Tom, SK; Tullis, E; Waters, V; Wettlaufer, J; Yau, Y | 1 |
| Konstan, MW; Mabie, JA; Mayer-Hamblett, N; Mink, DR; Moskowitz, SM; Pasta, DJ; Silva, SJ; Wagener, JS | 1 |
| Chaudhary, M; Sehgal, R; Shrivastava, SM | 1 |
| Bertram, C; Elborn, JS; Hodson, M | 1 |
| Gregori-Roig, P; Pantoja-Martínez, J; Valls-López, S; Yagüe-Muñoz, A | 1 |
| Benus, RF; Bernards, SA; Blok, HE; Bonten, MJ; de Jongh, BM; de Smet, AM; Frénay, IH; Jansz, AR; Kaan, JA; Kluytmans, JA; Leverstein-van Hall, MA; Mascini, EM; Oostdijk, EA; Pauw, W; Sturm, PD; Thieme Groen, ES; Thijsen, SF; van Asselt, GJ | 1 |
| Nagel, JL; Prescott, WA | 1 |
| Bes, M; Cavalié, L; Decousser, JW; Etienne, J; Laurent, F; Robert, J; Tristan, A | 1 |
| Elborn, JS; Parkins, MD | 1 |
| Ballmann, M; Geller, DE; Smyth, A | 1 |
| Alhede, M; Bjarnsholt, T; Christensen, LD; Eberl, L; Friedrich, K; Givskov, M; Høiby, N; Jakobsen, TH; Jensen, PØ; Larsen, TO; Moser, C; Nielsen, KF; Phipps, RK; Rasmussen, TB; Shanmugham, MS; Skindersoe, ME; Tanner, D; Uthe, F; van Gennip, M | 1 |
| Angyalosi, G; Balp, MM; Capkun-Niggli, G; Doering, G; Higashi, K; Jansen, JP; Littlewood, KJ; Tiddens, HA | 1 |
| Brokalaki, EI; Hillen, U; Sommerwerck, U; von Heinegg, EH | 1 |
| Alhariri, M; Omri, A | 1 |
| Jahnke, N; Remmington, T; Ryan, G | 1 |
| Elphick, H; Evans, GS; Everard, ML; Jones, A; Pettitt, E | 1 |
| Bitzan, MM; Hoffmann, IM; Iskandar, SS; Nagaraj, SK; Rubin, BK; Schechter, MS | 1 |
| Accurso, F; Burns, JL; Dovey, M; Emerson, J; Gibson, RL; Hamblett, N; Hiatt, P; Konstan, MW; McNamara, S; Moss, R; Ramsey, B; Retsch-Bogart, G; Rosenfeld, M; Wagener, J; Waltz, D; Wilmott, R; Yunker, A; Zeitlin, PL | 1 |
| Brazier, JL; Ducharme, MP; Lavigne, J; Marier, JF | 1 |
| Klepser, ME | 1 |
| Adrover, M; Alarcón, A; Badia, JR; Codina, C; Ferrer, M; Sarasa, M; Soy, D; Torres, A | 1 |
| Connett, GJ; Jones, G; Nicholson, T; Struthers, SL | 1 |
| Smith, AL | 1 |
| Bertran, S; Gómez, E; Jiménez de Anta, MT; Julià, A; Ruiz, J; Sauca, G; Vila, J; Vila, X | 1 |
| Zagólski, O | 1 |
| Korzeniewska, A; Stelmach, I; Stelmach, W | 1 |
| Duh, MS; Sacco, P; Toy, EL; Weiner, JR | 1 |
| Fitzpatrick, SB; Rosenstein, BJ | 1 |
| Duma, RJ | 1 |
| Miranda, DR; Stoutenbeek, CP; Van Saene, HK; Zandstra, DF | 1 |
| Weippl, G | 1 |
| Alfredson, H; Ericsson, A; Malmborg, AS; Strandvik, B | 1 |
| Christensen, HO; Høiby, N; Koch, C; Møller, AF; Møller, S; Permin, H | 1 |
| Fleming, PC; Gold, R; Isles, A; Jin, E; Levison, H | 1 |
| Connor, PJ; David, TJ; Phillips, BM | 1 |
| Ito, C; Kamada, H; Kikuiri, T; Masuyama, E; Nakagawa, S; Saito, A; Tango, M; Ujiie, A; Yajima, O; Yoshitani, S | 1 |
| Gui, D; Pittiruti, M; Ronconi, P | 1 |
| Belbusti, F; Ricci, L; Rosati, F | 1 |
| Kuch, H; Makowieczki, K | 1 |
| Alfredsson, H; Malmborg, AS; Strandvik, B | 1 |
| Braude, AC; Hornstein, A; Klein, M; Rebuck, AS; Vas, S | 1 |
| Hiraga, Y; Kikuchi, K; Nakahashi, M | 1 |
| Ramsey, B; Smith, AL | 1 |
| Davidson, TM; Light, M; Mitchell, M; Murphy, C; Smith, C | 1 |
| Bonten, MJ; Gaillard, CA; Johanson, WG; Smeets, HG; Stobberingh, EE; van der Geest, S; van Tiel, FH | 1 |
| Bakker, W; Heijerman, HG; Hermans, J; Touw, DJ; Vinks, AA | 1 |
| Hirose, S; Inoue, T; Ito, K; Mano, K; Mita, S; Morita, Y; Sukoh, M; Takahashi, T; Togano, Y; Yamanaka, K | 1 |
| Corti, G; Paradisi, F | 1 |
| Gialdroni Grassi, G | 1 |
| De Lalla, F; Mazzei, T; Mini, E; Novelli, A; Periti, P | 1 |
| Periti, P | 1 |
| Barson, WJ; Bates, RD; Cox, S; Jones, JW; McCoy, K; Nahata, MC; Young, G | 1 |
| Berman, SJ; Farkas, SA; Geckler, RW; Sieger, B | 1 |
| Bauernfeind, A; Döring, G; Przyklenk, B; Ratjen, F; Steinkamp, G; von der Hardt, H; Wiesemann, HG | 1 |
| Alvarado, F; Delgado, MA; Dorao, P; García, S; Goded, F; Herruzo, R; Ruza, F | 1 |
| Bernstein, J; Joshi, M; Kuye, O; Solomkin, J; Wester, BA | 1 |
| Campbell, PW; Saiman, L | 1 |
| Baghurst, PA; Colebatch, KA; Coulthard, KP; Hansman, D; Holmes, M; Jarvinen, A; Kennedy, D; Linke, RJ; Martin, A; Martin, AJ; Master, V; Onishko, CR; Parsons, DW; Roberts, GW; Roberts, ME | 1 |
| He, G; Li, H; Xu, H | 1 |
| Moss, RB | 1 |
| LiPuma, JJ | 1 |
| Bogle, S; Caldwell, NA; Conway, SP; Etherington, C; Setchfield, N; Whitehead, A | 1 |
| Appel, GB; Neu, HC | 1 |
| Bak-Pedersen, K; Friis, B; Jensen, K; Larsen, PK; Thomsen, J | 1 |
| Friis, B; Thomsen, J | 1 |
| Bodey, GP; Ketchel, S; Rodriguez, V | 1 |
| Bendush, CL; Weber, R | 1 |
| Neu, HC | 2 |
| Krasemann, C; Schmalz, W | 1 |
| Abbate, GF; Alagia, I; Altucci, P; Leonessa, V | 1 |
| Bondia Roman, A; De Castro Del Pozo, S; Macias Nuñez, JF; Sanchez Sanchez, R; Tabernero Romo, JM | 1 |
| Andersen, BM; Bergan, T; Brubakk, O; Bruun, JN; Døskeland, B; Hellum, KB; Hopen, G; Kalager, T; Rahm, V; von der Lippe, E | 1 |
| Igari, H; Ishiyama, N; Kanno, H; Kawashima, T; Kikuchi, N; Kohno, N; Kuriyama, T; Miyazaki, RM; Muraki, N; Onozaki, I | 1 |
| Altuna-Cuesta, A; Carrillo, A; Garcia, J; León, J; López, A; Martínez-Pellús, AJ; Rodríguez-Roldán, JM | 1 |
| Albus, A; Döring, G; Gappa, M; Potel, J; Steinkamp, G; Tümmler, B; von der Hardt, H | 1 |
| Malottke, R; Steinkamp, G; Tümmler, B; von der Hardt, H | 1 |
| Langrehr, D; Miranda, DR; Stoutenbeek, CP; van Saene, HK; Zandstra, DF | 1 |
| Morgan, JR; Paull, A | 1 |
| Black, PG; Bosso, JA | 1 |
| Gappa, M; Steinkamp, G; Tümmler, B; von der Hardt, H | 1 |
| Faragó, E; Kakuk, G; Löcsey, L | 1 |
| Black, P; Blumer, J; Craft, JC; Halsey, NA; McCarty, JM; Tilden, SJ; Waring, W | 1 |
| Bán, E; Ferencz, A; Prinz, G; Szalka, A | 1 |
| Jensen, T; Osterhammel, D; Osterhammel, P; Pedersen, SS | 1 |
| Rommes, JH; van Saene, HK; van Uffelen, R | 1 |
| Conway, SP; Littlewood, JM; Miller, MG; Ramsden, C | 1 |
| Grassi, C | 1 |
| Degener, JE; Driessen, O; Dzoljic-Danilovic, G; Hermans, J; Horrevorts, AM; Kerrebijn, KF; Michel, MF | 1 |
| Alexander, JM; Chrystyn, H | 1 |
| Ramirez-Ronda, CH; Rodriguez, JR | 1 |
| Nevárez, M; Ramírez-Ronda, CH; Rodríguez, JR | 1 |
| Holloway, WJ | 1 |
19 review(s) available for tobramycin and Infections, Respiratory
| Article | Year |
|---|---|
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis.
Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Cystic Fibrosis; Disease Progression; Forced Expiratory Volume; Humans; Injections, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Ticarcillin; Tobramycin | 2018 |
Inhaled antibiotics for lower airway infections.
Topics: Administration, Inhalation; Amikacin; Amphotericin B; Anti-Bacterial Agents; Aztreonam; Ceftazidime; Colistin; Cystic Fibrosis; Gentamicins; Humans; Nebulizers and Vaporizers; Respiratory Tract Infections; Tobramycin | 2014 |
Managing Pseudomonas aeruginosa respiratory infections in cystic fibrosis.
Topics: Administration, Inhalation; Administration, Oral; Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Fungal; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2015 |
Tobramycin inhalation powder (TOBI Podhaler) for the treatment of lung infection in patients with cystic fibrosis.
Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Dry Powder Inhalers; Humans; Lung; Opportunistic Infections; Prognosis; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2016 |
Extended-interval once-daily dosing of aminoglycosides in adult and pediatric patients with cystic fibrosis.
Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Child; Clinical Trials as Topic; Cystic Fibrosis; Drug Administration Schedule; Drug Monitoring; Humans; Middle Aged; Respiratory Tract Infections; Tobramycin; Treatment Outcome; Young Adult | 2010 |
Tobramycin Inhalation Powder™: a novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Cystic Fibrosis; Dry Powder Inhalers; Humans; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Tobramycin; Treatment Outcome | 2011 |
A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Load; Bayes Theorem; Biological Availability; Chronic Disease; Colistin; Cystic Fibrosis; Disease Progression; Female; Forced Expiratory Volume; Humans; Information Services; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2012 |
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis.
Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Cystic Fibrosis; Disease Progression; Humans; Injections, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Ticarcillin; Tobramycin | 2012 |
Role of nebulized antibiotics for the treatment of respiratory infections.
Topics: Administration, Inhalation; Aerosols; Anti-Infective Agents; Humans; Nebulizers and Vaporizers; Respiratory Tract Infections; Tobramycin | 2004 |
Inhaled antibiotic therapy: What drug? What dose? What regimen? What formulation?
Topics: Administration, Inhalation; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2002 |
Costs, quality of life and treatment compliance associated with antibiotic therapies in patients with cystic fibrosis: a review of the literature.
Topics: Anti-Bacterial Agents; Azithromycin; Cystic Fibrosis; Health Care Costs; Humans; Patient Compliance; Quality of Life; Respiratory Tract Infections; Severity of Illness Index; Tobramycin | 2008 |
Once-daily dosing regimen for aminoglycoside plus betalactam combination therapy of serious lower respiratory tract infections.
Topics: Administration, Oral; Anti-Bacterial Agents; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lactams; Respiratory Tract Infections; Tobramycin | 1995 |
The place of tobramycin in lower respiratory tract infections (LRTI).
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacteria; Cost-Benefit Analysis; Drug Administration Schedule; Drug Evaluation; Humans; Microbial Sensitivity Tests; Respiratory Tract Infections; Tobramycin | 1995 |
[Tobramycin--clinical pharmacology and chemotherapy].
Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Microbial; Humans; Respiratory Tract Infections; Tobramycin | 1996 |
Use of aerosolized antibiotics in patients with cystic fibrosis.
Topics: Aerosols; Anti-Bacterial Agents; Bacterial Infections; Cystic Fibrosis; Drug Monitoring; Drug Resistance, Microbial; Humans; Patient Selection; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1999 |
Gentamicin in 1978.
Topics: Amikacin; Animals; Bacterial Infections; Drug Synergism; Ear Diseases; Gentamicins; Humans; Kidney; Kidney Diseases; Netilmicin; Penicillin Resistance; Penicillins; Respiratory Tract Infections; Sisomicin; Tobramycin; Urinary Tract Infections | 1978 |
Tobramycin sulfate: a summary of worldwide experience from clinical trials.
Topics: Abdomen; Anti-Bacterial Agents; Bacterial Infections; Bone Diseases; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Digestive System; Humans; Kidney; Liver; Respiratory Tract Infections; Sepsis; Skin Diseases, Infectious; Tobramycin; Urinary Tract Infections; Vestibulocochlear Nerve | 1976 |
Tobramycin: an overview.
Topics: Adolescent; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Child; Child, Preschool; Depression, Chemical; Drug Resistance, Microbial; Drug Synergism; Humans; Infant; Kinetics; Male; Protein Biosynthesis; Pseudomonas; Respiratory Tract Infections; Sepsis; Skin Diseases, Infectious; Staphylococcus; Streptococcus; Tobramycin; Urinary Tract Infections | 1976 |
Respiratory infections: clinical evaluation.
Topics: Amikacin; Carbenicillin; Cefotaxime; Cystic Fibrosis; Drug Therapy, Combination; Enterobacteriaceae; Haemophilus influenzae; Humans; Piperacillin; Pseudomonas Infections; Respiratory Tract Infections; Streptococcus; Streptococcus pneumoniae; Tobramycin | 1985 |
34 trial(s) available for tobramycin and Infections, Respiratory
| Article | Year |
|---|---|
An 8 week open-label interventional multicenter study to explore the lung clearance index as endpoint for clinical trials in cystic fibrosis patients ≥8 years of age, chronically infected with Pseudomonas aeruginosa.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Pilot Projects; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Young Adult | 2020 |
Ease of use of tobramycin inhalation powder compared with nebulized tobramycin and colistimethate sodium: a crossover study in cystic fibrosis patients with pulmonary Pseudomonas aeruginosa infection.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Colistin; Cross-Over Studies; Cystic Fibrosis; Equipment Contamination; Equipment Design; Europe; Female; Forced Expiratory Volume; Humans; Lung; Male; Nebulizers and Vaporizers; Patient Satisfaction; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome; Young Adult | 2017 |
Nebulized tobramycin in the treatment of adult CF pulmonary exacerbations.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Disease Progression; England; Female; Humans; Injections, Intravenous; Kidney; Lung; Male; Nebulizers and Vaporizers; Pilot Projects; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Time Factors; Tobramycin; Treatment Outcome; Young Adult | 2014 |
Safety and efficacy of prolonged levofloxacin inhalation solution (APT-1026) treatment for cystic fibrosis and chronic Pseudomonas aeruginosa airway infection.
Topics: Administration, Inhalation; Adult; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Levofloxacin; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2016 |
Continuous alternating inhaled antibiotics for chronic pseudomonal infection in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Medication Therapy Management; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome | 2016 |
Pilot trial of tobramycin inhalation powder in cystic fibrosis patients with chronic Burkholderia cepacia complex infection.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Canada; Child; Cystic Fibrosis; Drug Monitoring; Female; Forced Expiratory Volume; Humans; Male; Pilot Projects; Respiratory Tract Infections; Sputum; Tobramycin; Treatment Outcome | 2017 |
Evaluation of efficacy and safety of fixed dose combination of ceftazidime-tobramycin in comparison with ceftazidime in lower respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Ceftazidime; Drug Combinations; Female; Humans; India; Male; Middle Aged; Respiratory Tract Infections; Tobramycin | 2009 |
Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis.
Topics: Administration, Inhalation; Age Factors; Anti-Bacterial Agents; Audiometry; Bronchoalveolar Lavage Fluid; Carrier State; Child, Preschool; Creatinine; Cystic Fibrosis; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Female; Genotype; Hearing Disorders; Humans; Kidney Diseases; Male; Oropharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Safety; Severity of Illness Index; Sputum; Tobramycin; Treatment Outcome | 2003 |
Disposition of instilled versus nebulized tobramycin and imipenem in ventilated intensive care unit (ICU) patients.
Topics: Administration, Inhalation; Aged; Anti-Bacterial Agents; Bronchi; Calibration; Chromatography, High Pressure Liquid; Clinical Protocols; Critical Care; Female; Humans; Imipenem; Immunoenzyme Techniques; Male; Middle Aged; Nebulizers and Vaporizers; Prospective Studies; Respiration, Artificial; Respiratory Tract Infections; Spectrophotometry, Ultraviolet; Tobramycin | 2004 |
Long-term benefits of inhaled tobramycin in children with cystic fibrosis: first clinical observations from Poland.
Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Humans; Male; Poland; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2008 |
Comparative clinical efficacy and safety of netilmicin and tobramycin in children with serious gram-negative infections.
Topics: Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Clinical Trials as Topic; Escherichia coli Infections; Female; Gentamicins; Humans; Male; Netilmicin; Respiratory Tract Infections; Tobramycin; Urinary Tract Infections | 1983 |
Ceftazidime treatment of chronic Pseudomonas aeruginosa respiratory tract infection in cystic fibrosis.
Topics: Adolescent; Adult; Carbenicillin; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Penicillin Resistance; Prospective Studies; Pseudomonas Infections; Random Allocation; Respiratory Function Tests; Respiratory Tract Infections; Tobramycin | 1983 |
[Clinical study on dosage schedule of tobramycin: controlled comparison between 180 mg b.i.d. and t.i.d].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Respiratory Tract Infections; Tobramycin | 1983 |
[Is it necessary to carry out antibiotic prophylaxis after surgical intervention? Prospective and randomized study in urologic surgery].
Topics: Clinical Trials as Topic; Female; Humans; Male; Postoperative Care; Prospective Studies; Random Allocation; Respiratory Tract Infections; Sepsis; Surgical Wound Infection; Tobramycin; Urinary Calculi; Urinary Tract Infections | 1983 |
[Clinical efficacy and safety of the cefamandole-tobramycin combination in the prevention and treatment of surgical infections in high-risk patients].
Topics: Adult; Age Factors; Aged; Cefamandole; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Postoperative Complications; Premedication; Respiratory Tract Infections; Risk; Surgical Wound Infection; Tobramycin; Urinary Tract Infections | 1983 |
Colonization in patients receiving and not receiving topical antimicrobial prophylaxis.
Topics: Administration, Topical; Aged; Amphotericin B; Colistin; Colony Count, Microbial; Cross Infection; Drug Therapy, Combination; Enterobacteriaceae; Female; Humans; Intensive Care Units; Male; Middle Aged; Oropharynx; Prospective Studies; Pseudomonadaceae; Respiratory Tract Infections; Tobramycin; Trachea | 1994 |
[Clinical evaluation of combination therapy of sulbactam/cefoperazone and aminoglycoside in respiratory tract infections].
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Bronchitis; Cefoperazone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pneumonia; Respiratory Tract Infections; Sulbactam; Tobramycin | 1994 |
Tissue penetration and pulmonary disposition of tobramycin.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Bronchoscopy; Critical Care; Diffusion; Drug Administration Schedule; Female; Humans; Injections, Intramuscular; Lung; Macrophages, Alveolar; Male; Middle Aged; Respiratory Tract Infections; Tissue Distribution; Tobramycin | 1995 |
Empiric treatment of hospital-acquired lower respiratory tract infections with meropenem or ceftazidime with tobramycin: a randomized study. Meropenem Lower Respiratory Infection Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Cross Infection; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Middle Aged; Prospective Studies; Respiratory Tract Infections; Thienamycins; Time Factors; Tobramycin | 1997 |
Placebo-controlled, double-blind, randomized study of aerosolized tobramycin for early treatment of Pseudomonas aeruginosa colonization in cystic fibrosis.
Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Pharynx; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Tobramycin | 1998 |
Prevention of nosocomial infection in a pediatric intensive care unit (PICU) through the use of selective digestive decontamination.
Topics: Adolescent; Antibiotic Prophylaxis; Child; Child, Preschool; Colistin; Cross Infection; Digestive System; Drug Therapy, Combination; Female; Hexetidine; Humans; Infant; Intensive Care Units, Pediatric; Male; Multiple Organ Failure; Multivariate Analysis; Nystatin; Prospective Studies; Regression Analysis; Respiratory Tract Infections; Severity of Illness Index; Tobramycin; Urinary Tract Infections | 1998 |
Piperacillin/tazobactam plus tobramycin versus ceftazidime plus tobramycin for the treatment of patients with nosocomial lower respiratory tract infection. Piperacillin/tazobactam Nosocomial Pneumonia Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ceftazidime; Cross Infection; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Piperacillin; Respiratory Tract Infections; Tobramycin | 1999 |
Efficacy of once-daily tobramycin monotherapy for acute pulmonary exacerbations of cystic fibrosis: a preliminary study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Child; Cystic Fibrosis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Pseudomonas Infections; Respiratory Function Tests; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome | 2001 |
Microbiological and immunologic considerations with aerosolized drug delivery.
Topics: Aerosols; Child; Colony Count, Microbial; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Long-Term Care; Microbial Sensitivity Tests; Nebulizers and Vaporizers; Opportunistic Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Stenotrophomonas maltophilia; Tobramycin | 2001 |
Once-daily tobramycin in the treatment of adult patients with cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Drug Administration Schedule; Forced Expiratory Volume; Humans; Lactams; Maximal Midexpiratory Flow Rate; Middle Aged; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Vital Capacity | 2002 |
Ciprofloxacin versus a tobramycin/cefuroxime combination in the treatment of serious systemic infections: a prospective, randomized and controlled study of efficacy and safety.
Topics: Adult; Aged; Bacteremia; Cefuroxime; Ciprofloxacin; Drug Therapy, Combination; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Respiratory Tract Infections; Tobramycin; Treatment Outcome; Urinary Tract Infections | 1992 |
[Clinical evaluation of combined therapy of ceftazidime and tobramycin for intractable pulmonary infection mainly caused by Pseudomonas aeruginosa].
Topics: Aged; Aged, 80 and over; Ceftazidime; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pneumonia; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1992 |
Prevention of nosocomial lung infection in ventilated patients: use of an antimicrobial pharyngeal nonabsorbable paste.
Topics: Administration, Topical; Adolescent; Adult; Aged; Amphotericin B; Child; Colistin; Cross Infection; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Oropharynx; Prospective Studies; Respiration, Artificial; Respiratory Tract Infections; Tobramycin | 1990 |
Controlled trial of aztreonam vs. tobramycin and azlocillin for acute pulmonary exacerbations of cystic fibrosis.
Topics: Adolescent; Azlocillin; Aztreonam; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Liver; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Respiratory Tract Infections; Sputum; Tobramycin; Transaminases | 1988 |
Comparison of piperacillin alone versus piperacillin plus tobramycin for treatment of respiratory infections in children with cystic fibrosis.
Topics: Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Half-Life; Humans; Infant; Piperacillin; Pseudomonas Infections; Random Allocation; Respiratory Tract Infections; Sputum; Tobramycin | 1988 |
[In vivo evaluation of the effectiveness of a cefamandole-tobramycin combination].
Topics: Cefamandole; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Respiratory Tract Infections; Sepsis; Tobramycin | 1986 |
Intensive treatment of pseudomonas chest infection in cystic fibrosis: a comparison of tobramycin and ticarcillin, and netilmicin and ticarcillin.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; Drug Combinations; Female; Gentamicins; Humans; Lung Volume Measurements; Male; Netilmicin; Penicillins; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Ticarcillin; Tobramycin | 1985 |
Efficacy and safety of aztreonam-clindamycin versus tobramycin-clindamycin in the treatment of lower respiratory tract infections caused by aerobic gram-negative bacilli.
Topics: Aged; Anti-Bacterial Agents; Aztreonam; Bacteria, Aerobic; Clindamycin; Drug Therapy, Combination; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Respiratory Tract Infections; Tobramycin | 1985 |
Treatment of infections in hospitalized patients with ticarcillin plus clavulanic acid. A comparative study.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefoxitin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Female; Gram-Negative Bacteria; Hospitalization; Humans; Male; Penicillins; Piperacillin; Respiratory Tract Infections; Sepsis; Ticarcillin; Tobramycin | 1985 |
65 other study(ies) available for tobramycin and Infections, Respiratory
| Article | Year |
|---|---|
Clinical prediction tool to identify patients with Pseudomonas aeruginosa respiratory tract infections at greatest risk for multidrug resistance.
Topics: Adult; Anti-Bacterial Agents; Case-Control Studies; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Predictive Value of Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Retrospective Studies; Risk; Risk Factors | 2007 |
Research Note: Epidemiological cutoff values and acquired resistance mechanisms of three veterinary antibiotics against Escherichia coli from chicken respiratory tract infections.
Topics: Animals; Anti-Bacterial Agents; Chickens; China; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Microbial Sensitivity Tests; Nebramycin; Poultry Diseases; Respiratory Tract Infections; Thiamphenicol | 2021 |
In vitro evaluation of Pseudomonas aeruginosa chronic lung infection models: Are agar and calcium-alginate beads interchangeable?
Topics: Agar; Alginates; Animals; Anti-Bacterial Agents; Ciprofloxacin; Disease Models, Animal; Lung; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2019 |
Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic
Topics: Animals; Anti-Bacterial Agents; Chronic Disease; Drug Development; Lung; Male; Models, Biological; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Respiratory Tract Infections; Tobramycin | 2020 |
Ototoxicity in cystic fibrosis patients receiving intravenous tobramycin for acute pulmonary exacerbation: Ototoxicity following tobramycin treatment.
Topics: Administration, Intravenous; Adolescent; Adult; Aminoglycosides; Audiometry, Pure-Tone; Cystic Fibrosis; Female; Hearing Loss; Humans; Male; Middle Aged; Ototoxicity; Respiratory Tract Infections; Symptom Flare Up; Tobramycin | 2021 |
Optimization and characterization of a murine lung infection model for the evaluation of novel therapeutics against Burkholderia cenocepacia.
Topics: Animals; Anti-Bacterial Agents; Burkholderia cenocepacia; Burkholderia Infections; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Liver; Lung; Mice; Mice, Inbred BALB C; Pneumonia; Respiratory Tract Infections; Spleen; Tobramycin | 2017 |
Nano into Micro Formulations of Tobramycin for the Treatment of Pseudomonas aeruginosa Infections in Cystic Fibrosis.
Topics: Anti-Bacterial Agents; Biofilms; Bronchi; Cells, Cultured; Chemistry, Pharmaceutical; Cystic Fibrosis; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Dry Powder Inhalers; Epithelial Cells; Humans; Nanoparticles; Particle Size; Polyelectrolytes; Polymers; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2017 |
PEGylation of Tobramycin Improves Mucus Penetration and Antimicrobial Activity against Pseudomonas aeruginosa Biofilms in Vitro.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Chickens; Cystic Fibrosis; Humans; Lung; Microbial Sensitivity Tests; Mucus; Polyethylene Glycols; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Swine; Tobramycin | 2018 |
Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Bacteriological Techniques; Cystic Fibrosis; Humans; Hyperbaric Oxygenation; Lung; Models, Biological; Neutrophils; Oxygen; Pseudomonas aeruginosa; Respiratory Tract Infections; Tobramycin | 2019 |
A real world evaluation of the long-term efficacy of strategies to prevent chronic Pseudomonas aeruginosa pulmonary infection in children with cystic fibrosis.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Cohort Studies; Cystic Fibrosis; Female; Humans; Infant; Infant, Newborn; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Retrospective Studies; Tobramycin | 2019 |
New co-spray-dried tobramycin nanoparticles-clarithromycin inhaled powder systems for lung infection therapy in cystic fibrosis patients.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Clarithromycin; Cystic Fibrosis; Desiccation; Drug Delivery Systems; Humans; Lung; Lung Diseases; Nanoparticles; Powders; Respiratory Tract Infections; Solubility; Tobramycin | 2013 |
NICE guidance on colistimethate sodium and tobramycin for pseudomonas lung infection in cystic fibrosis.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Clinical Trials as Topic; Colistin; Cystic Fibrosis; Drug Monitoring; Drug Therapy, Combination; Dry Powder Inhalers; Humans; Practice Guidelines as Topic; Pseudomonas Infections; Respiratory Function Tests; Respiratory Tract Infections; State Medicine; Tobramycin; United Kingdom | 2013 |
Colistin and tobramycin resistance during long- term use of selective decontamination strategies in the intensive care unit: a post hoc analysis.
Topics: Anti-Bacterial Agents; Colistin; Decontamination; Drug Resistance, Bacterial; Gastrointestinal Tract; Gram-Negative Bacteria; Humans; Intensive Care Units; Oropharynx; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin | 2015 |
Novel inhaled combined antibiotic formulations in the treatment of Pseudomonas aeruginosa airways infections in cystic fibrosis.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Clinical Trials as Topic; Cystic Fibrosis; Drug Combinations; Fosfomycin; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2015 |
Impairment of Pseudomonas aeruginosa Biofilm Resistance to Antibiotics by Combining the Drugs with a New Quorum-Sensing Inhibitor.
Topics: Amides; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Synergism; Drug Therapy, Combination; Humans; Lung; Microscopy, Confocal; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrimidines; Quorum Sensing; Respiratory Tract Infections; Tobramycin | 2015 |
Sequential Treatment of Biofilms with Aztreonam and Tobramycin Is a Novel Strategy for Combating Pseudomonas aeruginosa Chronic Respiratory Infections.
Topics: Anti-Bacterial Agents; Aztreonam; Biofilms; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2016 |
Shifting patterns of inhaled antibiotic use in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Colistin; Cystic Fibrosis; Drug Utilization; Female; Humans; Male; Respiratory Tract Infections; Tobramycin | 2008 |
Implementation of European standards of care for cystic fibrosis--control and treatment of infection.
Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Bacterial Infections; Burkholderia cepacia; Burkholderia Infections; Child; Child, Preschool; Ciprofloxacin; Colistin; Cystic Fibrosis; Europe; Guideline Adherence; Humans; Infection Control; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Surveys and Questionnaires; Tobramycin; Young Adult | 2009 |
[Ochrobactrum anthropi bacteremia in a child with cystic fibrosis].
Topics: Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Child; Cholecystitis; Cystic Fibrosis; Disease Susceptibility; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Male; Ochrobactrum anthropi; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2010 |
Ecological effects of selective decontamination on resistant gram-negative bacterial colonization.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Ceftazidime; Ciprofloxacin; Cross Infection; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Intensive Care Units; Longitudinal Studies; Rectum; Respiratory System; Respiratory Tract Infections; Tobramycin | 2010 |
Panton-valentine leukocidin-positive and toxic shock syndrome toxin 1-positive methicillin-resistant Staphylococcus aureus: a French multicenter prospective study in 2008.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Bacterial Toxins; Community-Acquired Infections; Enterotoxins; Exotoxins; France; Humans; Kanamycin; Leukocidins; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Respiratory Tract Infections; Skin Diseases, Bacterial; Superantigens; Tetracycline; Tobramycin | 2011 |
Therapeutic approaches to chronic cystic fibrosis respiratory infections with available, emerging aerosolized antibiotics.
Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2011 |
Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Chemical Fractionation; Disulfides; Drug Synergism; Garlic; Gene Expression Regulation, Bacterial; Genes, Reporter; Glycolipids; Mice; Neutrophils; Plant Extracts; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Respiratory Tract Infections; Sulfoxides; Tobramycin; Virulence Factors | 2012 |
Ochroconis gallopavum infection in a lung transplant recipient: report of a case.
Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Biopsy; Bronchiolitis Obliterans; Disease Progression; Drug Administration Schedule; Enterobacter cloacae; Enterococcus; Fatal Outcome; Humans; Imipenem; Lung Transplantation; Male; Opportunistic Infections; Phaeohyphomycosis; Pyrimidines; Respiratory Tract Infections; Skin; Sputum; Tobramycin; Treatment Outcome; Triazoles; Voriconazole | 2012 |
Efficacy of liposomal bismuth-ethanedithiol-loaded tobramycin after intratracheal administration in rats with pulmonary Pseudomonas aeruginosa infection.
Topics: Acyl-Butyrolactones; Administration, Inhalation; Animals; Anti-Bacterial Agents; Biological Availability; Bismuth; Drug Compounding; Kidney; Liposomes; Lung; Mercaptoethanol; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Rats; Respiratory Tract Infections; Tobramycin; Treatment Outcome; Virulence Factors | 2013 |
Colistin stimulates the activity of neutrophil elastase and Pseudomonas aeruginosa elastase.
Topics: Adolescent; Adult; alpha 1-Antitrypsin; Amino Acid Chloromethyl Ketones; Anti-Bacterial Agents; Anticoagulants; Bacterial Proteins; Ceftazidime; Child; Colistin; Cystic Fibrosis; Enzyme Activation; Erythromycin; Female; Gentamicins; Heparin; Humans; In Vitro Techniques; Leukocyte Elastase; Male; Metalloendopeptidases; Respiratory Tract Infections; Serine Proteinase Inhibitors; Sputum; Tobramycin | 2002 |
Acute renal failure in cystic fibrosis: association with inhaled tobramycin therapy.
Topics: Acute Kidney Injury; Administration, Inhalation; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2002 |
Liposomal tobramycin against pulmonary infections of Pseudomonas aeruginosa: a pharmacokinetic and efficacy study following single and multiple intratracheal administrations in rats.
Topics: Animals; Injections, Spinal; Liposomes; Lung; Male; Pseudomonas aeruginosa; Rats; Rats, Sprague-Dawley; Respiratory Tract Infections; Tobramycin | 2003 |
Falsely elevated serum tobramycin levels in a patient receiving nebulised tobramycin.
Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Cystic Fibrosis; Drug Monitoring; False Positive Reactions; Female; Humans; Infusions, Intravenous; Nebulizers and Vaporizers; Respiratory Tract Infections; Tobramycin | 2002 |
Isolation of an amikacin-resistant Escherichia coli strain after tobramycin treatment of previous recurrent episodes of respiratory tract infections caused by Pseudomonas aeruginosa.
Topics: Amikacin; Anti-Bacterial Agents; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Respiratory Tract Infections; Tobramycin | 2005 |
[Vestibular tests in infants after treatment with aminoglycosides].
Topics: Amikacin; Anti-Bacterial Agents; Drug Combinations; Female; Gentamicins; Humans; Infant; Male; Respiratory Tract Infections; Tobramycin; Vestibular Function Tests | 2005 |
Moxalactam-tobramycin-resistant Pseudomonas aeruginosa isolates in patients with cystic fibrosis.
Topics: Adolescent; Anti-Bacterial Agents; Cephalosporins; Cephamycins; Child; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Male; Moxalactam; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1983 |
Summary of comparative clinical studies of ceftizoxime and cefamandole, cefazolin and tobramycin.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefamandole; Cefazolin; Cefotaxime; Ceftizoxime; Cephalosporins; Humans; Respiratory Tract Infections; Skin Diseases, Infectious; Tobramycin; Urinary Tract Infections | 1982 |
A new technique of infection prevention in the intensive care unit by selective decontamination of the digestive tract.
Topics: Anti-Bacterial Agents; Cefotaxime; Cross Infection; Digestive System; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Intensive Care Units; Polymyxins; Respiratory Tract Infections; Sepsis; Tobramycin | 1983 |
Clinical results and pharmacokinetics of ceftazidime treatment in patients with cystic fibrosis.
Topics: Adolescent; Adult; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Half-Life; Humans; Kinetics; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Tobramycin | 1983 |
Ceftazidime alone and in combination in patients with cystic fibrosis: lack of efficacy in treatment of severe respiratory infections caused by Pseudomonas cepacia.
Topics: Adolescent; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Piperacillin; Pseudomonas Infections; Respiratory Tract Infections; Sulfamethoxazole; Tobramycin; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1983 |
Ceftazidime - a significant advance in the treatment of cystic fibrosis.
Topics: Adolescent; Adult; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Floxacillin; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Staphylococcal Infections; Tobramycin | 1983 |
Evaluation of the clinical efficiency of brulamycin in the treatment of infections of the respiratory and urinary tracts.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Respiratory Tract Infections; Tobramycin; Urinary Tract Infections | 1984 |
Azlocillin in cystic fibrosis.
Topics: Adolescent; Adult; Azlocillin; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Gentamicins; Humans; Male; Penicillins; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1983 |
Pulmonary disposition of tobramycin.
Topics: Adult; Aged; Anti-Bacterial Agents; Biological Transport; Bronchi; Exudates and Transudates; Female; Humans; Kinetics; Lung; Male; Middle Aged; Protein Binding; Respiratory Tract Infections; Therapeutic Irrigation; Tobramycin | 1983 |
[Clinical studies on tobramycin by intravenous drip infusion for Pseudomonas aeruginosa infection in chronic respiratory diseases (author's transl)].
Topics: Adult; Aged; Anti-Bacterial Agents; Chronic Disease; Drug Evaluation; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Pseudomonas Infections; Radiography; Respiratory Tract Infections; Tobramycin | 1981 |
Aerosol administration of antibiotics.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Child, Preschool; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Respiratory Function Tests; Respiratory Tract Infections; Tobramycin | 1995 |
Management of chronic sinusitis in cystic fibrosis.
Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Clinical Protocols; Combined Modality Therapy; Cystic Fibrosis; Endoscopy; Humans; Lung Transplantation; Maxillary Sinus; Nasal Polyps; Nasal Septum; Pneumonia, Bacterial; Preoperative Care; Pseudomonas Infections; Respiratory Tract Infections; Rhinitis; Sinusitis; Sodium Chloride; Therapeutic Irrigation; Tobramycin; Turbinates | 1995 |
Suggestions for the optimization of the initial tobramycin dose in adolescent and adult patients with cystic fibrosis.
Topics: Adolescent; Adult; Body Weight; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Humans; Male; Mathematics; Pseudomonas Infections; Regression Analysis; Respiratory Tract Infections; Retrospective Studies; Tobramycin | 1994 |
Pharmacokinetics and safety of tobramycin after once-daily administration in patients with cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cost-Benefit Analysis; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fluorescence Polarization Immunoassay; Half-Life; Humans; Length of Stay; Male; Respiratory Tract Infections; Safety; Tobramycin; Treatment Outcome | 1997 |
[The relationship between different serological types of Pseudomonas aeruginosa strain in lower respiratory tract and its clinical significance].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bronchiectasis; Drug Resistance, Microbial; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Serotyping; Tobramycin | 1998 |
Administration of aerosolized antibiotics in cystic fibrosis patients.
Topics: Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Nebulizers and Vaporizers; Opportunistic Infections; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2001 |
Tobramycin ototoxicity. Repeated courses of high dosage treatment in children with cystic fibrosis.
Topics: Anti-Bacterial Agents; Child; Cystic Fibrosis; Drug Administration Schedule; Ear Diseases; Female; Hearing Disorders; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1979 |
High dosage tobramycin treatment of children with cystic fibrosis. Bacteriological effect and clinical ototoxicity.
Topics: Anti-Bacterial Agents; Carbenicillin; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1979 |
Carbenicillin plus cefamandole in the treatment of infections in patients with cancer.
Topics: Adolescent; Aeromonas; Aged; Bacterial Infections; Carbenicillin; Cefamandole; Cephalosporins; Corynebacterium Infections; Drug Therapy, Combination; Enterobacteriaceae Infections; Female; Flavobacterium; Humans; Listeriosis; Male; Middle Aged; Neoplasms; Respiratory Tract Infections; Sepsis; Tobramycin | 1978 |
[Tobramycin sensitivity of bacteria from the Klebsiella-Enterobacter group (author's transl)].
Topics: Anti-Bacterial Agents; Humans; Klebsiella; Microbial Sensitivity Tests; Respiratory Tract Infections; Tobramycin; Urinary Tract Infections | 1976 |
Clinical evaluation of tobramycin in respiratory and systemic infections in immunodepressed and normal patients.
Topics: Anti-Bacterial Agents; Bacterial Infections; Humans; Immunosuppression Therapy; Pneumonia; Respiratory Tract Infections; Sepsis; Tobramycin | 1976 |
[Acute renal failure caused by tobramycin].
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Female; Humans; Respiratory Tract Infections; Tobramycin | 1976 |
Newer antimicrobial agents.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefazolin; Cephalosporins; Cephapirin; Cephradine; Clindamycin; Drug Combinations; Gastrointestinal Diseases; Humans; Minocycline; Penicillins; Respiratory Tract Infections; Sexually Transmitted Diseases; Sulfamethoxazole; Tobramycin; Trimethoprim; Urinary Tract Infections | 1975 |
Long-term tobramycin aerosol therapy in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Aerosols; Child; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin | 1989 |
Treatment of pseudomonas aeruginosa colonisation in cystic fibrosis.
Topics: Adolescent; Azlocillin; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Serotyping; Sputum; Time Factors; Tobramycin | 1989 |
The effect of oropharyngeal decontamination using topical nonabsorbable antibiotics on the incidence of nosocomial respiratory tract infections in multiple trauma patients.
Topics: Administration, Topical; Adolescent; Adult; Amphotericin B; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cross Infection; Decontamination; Female; Humans; Intestines; Male; Middle Aged; Oropharynx; Pneumonia; Pneumonia, Staphylococcal; Polymyxins; Prospective Studies; Respiratory System; Respiratory Tract Infections; Retrospective Studies; Tobramycin; Wounds and Injuries | 1987 |
Emergence of ceftriaxone-resistant strains of Pseudomonas aeruginosa in cystic fibrosis patients.
Topics: Adolescent; Adult; beta-Lactamases; Ceftriaxone; Child; Cystic Fibrosis; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1986 |
Long-term tobramycin aerosol therapy of chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Aerosols; Child; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin | 1988 |
Experience with brulamycin therapy in dialysed patients.
Topics: Adolescent; Adult; Bacterial Infections; Drug Administration Routes; Female; Humans; Male; Middle Aged; Peritoneal Dialysis; Renal Dialysis; Respiratory Tract Infections; Tobramycin; Urinary Tract Infections | 1988 |
Cumulative and acute toxicity of repeated high-dose tobramycin treatment in cystic fibrosis.
Topics: Adolescent; Adult; Child; Cystic Fibrosis; Female; Hearing Loss, Sensorineural; Humans; Kidney Diseases; Labyrinth Diseases; Male; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 1987 |
Preventing lower airway colonization and infection in mechanically ventilated patients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Colistin; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Humans; Male; Middle Aged; Pneumonia; Prospective Studies; Respiration, Artificial; Respiratory System; Respiratory Tract Infections; Tobramycin | 1987 |
Pharmacokinetics of tobramycin in patients with cystic fibrosis. Implications for the dosing interval.
Topics: Adolescent; Adult; Age Factors; Body Weight; Child; Chronic Disease; Cystic Fibrosis; Female; Half-Life; Humans; Kinetics; Male; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin | 1985 |
Dosage of tobramycin in cystic fibrosis--a short report.
Topics: Child; Cystic Fibrosis; Female; Half-Life; Humans; Respiratory Tract Infections; Tobramycin | 1985 |
Efficacy and safety of aztreonam versus tobramycin for aerobic gram-negative bacilli lower respiratory tract infections.
Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Drug Administration Schedule; Drug Evaluation; Gram-Negative Aerobic Bacteria; Humans; Random Allocation; Respiratory Tract Infections; Tobramycin | 1985 |