Page last updated: 2024-08-23

tobramycin and Cystic Fibrosis

tobramycin has been researched along with Cystic Fibrosis in 635 studies

Research

Studies (635)

Timeframe	Studies, this research(%)	All Research%
pre-1990	91 (14.33)	18.7374
1990's	78 (12.28)	18.2507
2000's	164 (25.83)	29.6817
2010's	232 (36.54)	24.3611
2020's	70 (11.02)	2.80

Authors

Authors	Studies
Juan, C; Maciá, MD; Mena, A; Mulet, X; Oliver, A; Pérez, JL	1
Attrée, I; Ducruix, A; El Garch, F; Llanes, C; Muller, C; Phan, G; Plésiat, P; Vettoretti, L	1
Christiansen, LE; Ciofu, O; Høiby, N; Kirkby, N; Mandsberg, LF; Poulsen, HE	1
Burns, JL; Dudley, MN; Griffith, DC; King, P; Lomovskaya, O	1
Beceiro, A; Bou, G; Doumith, M; Livermore, DM; Tomás, M; Turton, JF; Warner, M; Woodford, N	1
Blau, H; Kadosh, D; Kalamaro, V; Landau, E; Mantin, H; Mei-Zahav, M; Mussaffi, H; Prais, D; Quittner, A; Taizi, T	1
Abbate, V; Bruce, KD; Cilibrizzi, A; Faure, ME; Hider, RC	1
Haines, RR; Hammer, KA; Putsathit, P; Tai, AS	1
Baines, A; Billings, JL; Caverly, LJ; Chmiel, JF; GIbson, RL; Heltshe, SL; Kirby, S; Kong, A; Lascano, J; Mayer-Hamblett, N; Morgan, SJ; Nichols, DP; Nick, JA; Retsch-Bogart, G; Sadeghi, H; Saiman, L; Singh, PK	1
Bao, X; Bové, M; Coenye, T	1
Cloutier, I; El Hassani, M; Marsot, A; Pilote, S; Simard, C; Soufsaf, S	1
Brodlie, M; Shenton, G; Tumelty, H	1
Buyuksahin, HN; Dogru, D; Emiralioglu, N; Guzelkas, I; Hazirolan, G; Kiper, N; Özçelik, U; Ozsezen, B; Şener, B; Sunman, B; Tural, DA; Yalcin, E	1
Fiel, SB; Roesch, EA	1
Bjarnsholt, T; Jacobs, HM; Lopatto, E; O'Neal, L; Parsek, MR; Wozniak, DJ	1
De Fabritiis, S; Di Bonaventura, G; Di Nicola, M; Lupetti, V; Piccirilli, A; Pompilio, A; Porreca, A	1
Crass, RL; Fitzgerald, LJ; Han, MK; Jia, S; Lenhan, BE; Lipp, MA; Patel, TS; Simon, RH	1
Hosseini, M; Marasini, N; Sheikh, Z; Spicer, PT; Traini, D; Wong, CYJ; Xin Ong, H; Young, P	1
Charbek, E; Rowbotham, NJ; Smith, S	2
Chen, C; Gao, L; Qiao, X; Wan, Y; Wang, Y; Zhang, L	1
Koloskoff, K; Marsot, A; Matouk, E; Thirion, DJG	1
Birket, SE; Bollar, GE; Keith, JD; Kiedrowski, MR; Oden, AM	1
Fitzgerald, DA; Imani, S; Lai, T; Robinson, PD; Sandaradura, I; Selvadurai, H	1
Rowbotham, NJ; Smith, S	1
Aldogan, EH; Hacioglu, M; Yilmaz, FN	1
Friman, VP; Law, JP; Wood, AJ	1
Altenburg, J; Berk, Y; Boersma, WG; Bronsveld, I; de Kruif, MD; Heijerman, HGM; Rozemeijer, W; Snijders, D; Terpstra, LC	1
Coburn, B; DiGiandomenico, A; Eisha, S; Grana-Miraglia, L; Guttman, DS; Hoffman, LR; Howell, PL; McDonald, N; Morris, AJ; Nguyen, D; Park, S; Parsek, MR; Rooney, AM; Wang, P; Waters, VJ; Wozniak, DJ; Yau, YCW	1
Durham, ME; Gilstrap, DL; Green, CL; Kram, BL; Kram, SJ; Kuhrt, M; Parish, A; Schultheis, JM	1
Déziel, E; Groleau, MC; Hampton, TH; Hogan, DA; Jean-Pierre, F; O'Toole, GA; Schultz, D	1
Cloutier, I; El Hassani, M; Koloskoff, K; Marsot, A; Matouk, E; Pilote, S; Simard, C; Thirion, DJG	1
Dell, SD; Gatt, D; Ratjen, F; Shaw, M; Solomon, M; Wee, W	1
Dittrich, AM; Dopfer, C; Fuge, J; Grewendorf, S; Hansen, G; Happle, C; Junge, S; Kontsendorn, J; Rudolf, I; Schütz, K; Sedlacek, L	1
Baniasadi, S; Hassanzad, M; Kouhestani, F	1
Dickinson, KM; Mogayzel, PJ	1
Dumke, M; Hafkemeyer, S; Hammermann, J; Naehrig, S; Naehrlich, L; Schulte-Hubbert, B; Sieber, S	1
Baladi, B; Calmels, MN; Concordet, D; Gallois, Y; Gandia, P; Madaule, J; Mittaine, M; Murris, M; Valenzuela, F	1
Langton Hewer, SC; Rowbotham, NJ; Smith, S; Smyth, AR; Yule, A	1
Beigverdi, R; Emaneini, M; Halimi, S; Jabalameli, F; Siroosi, M	1
Harris, JK; Mayer-Hamblett, N; Ramsey, BW; Retsch-Bogart, G; Robertson, CE; Sagel, SD; Stevens, MJ; Wagner, BD; Zemanick, ET	1
Brown, C; Morrison, L; Stanford, G	1
Albasri, M; Andrinopoulou, ER; Arets, HGM; Heijerman, HGM; Majoor, CJ; Meerburg, JJ; Tiddens, HAWM; van der Eerden, MM; van der Wiel, EC	1
Bilton, D; Cipolli, M; Clancy, JP; Eagle, G; Fajac, I; Galeva, I; Gupta, R; Konstan, MW; Liu, K; McGinnis, JP; Minic, P; Pressler, T; Quittner, AL; Sands, D; Solé, A	1
Carroll, WD; Ditchfield, N; Gilchrist, FJ	1
Bell, SC; Brockway, B; Lamont, IL; Patrick, WM; Ramsay, KA; Reid, DW; Wardell, SJT; Winstanley, C	1
Elgaher, WAM; Haupenthal, J; Hirsch, AKH; Lababidi, N; Ofosu Kissi, E; Rades, T; Schneider, M; Schwarz, BC; Sigal, V	1
Cogen, JD; Goss, CH; Heltshe, SL; Nichols, DP; Odem-Davis, K; Ren, CL; Skalland, M; Somayaji, R	1
Agarwal, A; Nash, EF; Palser, S; Smith, S; Smyth, AR	1
Bauza, C; Berman, DM; Chojnacki, M; Dudas, RA; Dunman, PM; Fadrowski, JJ; Goldenberg, NA; Morrison, JM	1
Greenhalf, W; Jaki, T; Jones, AP; McWilliam, SJ; Pirmohamed, M; Rosala-Hallas, A; Shaw, V; Smyth, AR; Smyth, RL	1
Heijerman, HGM; Neef, C; Touw, DJ; van der Meer, R; van Maarseveen, EM	1
Christophersen, L; Henneberg, KÅ; Høiby, N; Kragh, KN; Laulund, AS; Lerche, CJ; Moser, C; Sams, T; Schwartz, FA; Svanekjær, T; Thomsen, K	1
Armijo, LM; Brandt, YI; Cook, NC; Huber, DL; Kopciuch, M; Monson, TC; Osiński, M; Rivera, AC; Smyth, HDC; Wawrzyniec, SJ; Withers, NJ	1
Andrinopoulou, ER; Bos, AC; Hamed, K; Mastoridis, P; Meerburg, JJ; Shin, H; Tiddens, HAWM; van Straten, M	1
Bear, CE; Deber, CM; Laselva, O; Stone, TA	1
Cheng, Z; Daboor, SM; Rohde, JR	1
Mellies, U; Naehrig, S; Sieder, C; Sutharsan, S; Ziegler, J	1
Albright, JC; Houck, AP; Pettit, RS	1
Bautista, G; Blackledge, M; Borenstein, E; Brittnacher, MJ; Eng, A; Hayden, HS; Hoffman, LR; LiPuma, JJ; Majors, C; McNamara, S; Miller, SI; Nay, L; Nelson, MT; Ratjen, A; Ravishankar, S; Simon, RH; Vo, AT; Weiss, EJ; Wolter, DJ	1
Garinis, A; Gleser, M; Johns, A; Larsen, E; Vachhani, J	1
Cogen, JD; Faino, AV; Gibson, RL; Hoffman, LR; Kronman, MP; Nichols, DP; Onchiri, F; Rosenfeld, M	1
Autry, EB; Beckman, EJ; Gardner, BM; Kuhn, RJ; Saad, A; Schadler, A; Studtmann, AE; Wurth, MA; Young, MR	1
Ashby, D; Brown, M; Hewer, SCL; Hickey, H; Jones, AP; Kenna, D; Smyth, AR; Thompson, A; Williamson, PR	1
Burr, LD; Keating, RL; Leong, LEX; Mobegi, FM; Papanicolas, LE; Richard, A; Rogers, GB; Sims, SK; Taylor, SL; Wesselingh, S	1
Dorgan, D; Fifer, RC; Flume, PA; Harruff, EE; Jain, R; Kil, J; Kim, YJM; Ortiz, MGT; Poth, EA; Shoup, AG	1
Chin, M; Somayaji, R; Thornton, C	1
Benedetti, A; Kwong, K; Nguyen, D; Waters, V; Yau, Y	1
Goss, CH; Heltshe, S; Khan, U; Laguna, TA; Pittman, JE; Sanders, DB	1
Kemper, EM; Majoor, CJ; Vonk, SEM; Weersink, EJM	1
Bradbury, P; Kassiou, M; Ong, HX; Pozzoli, M; Reekie, TA; Robinson, PD; Sheikh, Z; Traini, D; Young, PM	1
Barry, L; Drennan, PG; Matthey, J; Sivam, S; Thoma, Y; van Hal, SJ	1
Carvalho-Wodarz, CS; Horstmann, JC; Lehr, CM; Prestidge, CA; Thomas, N; Thorn, CR	1
Caverly, LJ; Chaffee, VD; Dillman, NO; Ochs, MA	1
Cheah, R; Le, T; Lord, L; Pignataro, S; Simioni, D	1
Cambridge, L; Millar, BC; Moore, JE; Ollman-Selinger, M	1
Burrus, TE; Pettit, RS; Vogt, H	1
Autry, EB; Bosko, KA; Gardner, BM; Kuhn, RJ; Landmesser, KB; Schadler, A	1
Kolls, JK; Lu, S	1
Beaudoin, T; Cw Yau, Y; DiGiandomenico, A; Guttman, DS; Guttman, KM; Hoffman, LR; Jackson, L; Lynne Howell, P; Morris, AJ; Nguyen, D; Parsek, MR; Reichhardt, C; Uwumarenogie, S; Waters, VJ; Wozniak, DJ	1
Blankenship, CA; Dong, M; Hunter, LL; McPhail, G; Rodriguez, AV; Vinks, AA	1
Bhatt, J; Nevitt, SJ; Smyth, AR	1
Cogen, J; Rosenfeld, M	1
Langton Hewer, SC; Smyth, AR	3
LeCleir, LK; Pettit, RS	1
Debonnett, L; Hamed, K	1
Cao, W; Debonnett, L; Greenwood, J; Hamed, K; Mastoridis, P; Nash, EF; Schwarz, C; Sommerwerck, U; Tamm, M	1
Anumolu, SS; Koehne-Voss, S; Wang, X; Yu, J	1
Debonnett, L; Gunda, P; Hamed, K; Panguluri, S	1
Baker, SM; Giatpaiboon, S; LiPuma, JJ; Narayanaswamy, VP; Townsend, SM; Wiesmann, WP	1
Armstrong, ME; Bernhagen, J; Bucala, R; Caraher, E; Cooke, G; Donnelly, SC; Fabre, A; Jülicher, K; Kennedy, S; Leng, L; Maher, L; Mawhinney, L; McKone, EF; O'Dwyer, D; O'Reilly, C; Schaffer, K; Tynan, A	1
Ausubel, FM; Gutu, AD; Hebert, W; Joseph-McCarthy, D; Koeva, M; Moskowitz, SM; O'Toole, GA; Wager, JD; Yonker, LM	1
Andrinopoulou, ER; Bos, AC; Janssens, HM; Mouton, JW; Tiddens, HAWM; van Westreenen, M	1
Cavallaro, G; Craparo, EF; Cusimano, MG; Giammona, G; Porsio, B; Schillaci, D	1
Burgard, M; Hennig, S; Sandaradura, I; Stacey, S; van Hal, SJ	1
Chaaban, H; Johnson, PN; Lepa, TM; Miller, JL; Ranallo, C; Skrepnek, GH	1
Barras, M; Gao, Y; Hennig, S	2
Hayes, D; Li, SS; Morgan, WJ; Tobias, JD; Tumin, D	1
Antony, VB; Carden, JL; Gaggar, A; Garcia, BA; Goodwin, DL; Leon, K; Rowe, SM; Smith, TA; Solomon, GM	1
Bahamondez-Canas, TF; Leal, J; Smyth, HDC; Tewes, F; Zhang, H	1
Antoine, DJ; Jorgensen, AL; McWilliam, SJ; Pirmohamed, M; Smyth, RL	1
Alon, N; Angyalosi, G; Asherova, I; Maykut, R; McKinney, ML; Moeller, A; Ratjen, F	1
Bartezaghi, M; Blasi, F; Carnovale, V; Cimino, G; Lucidi, V; Messore, B; Muscianisi, E; Porpiglia, PA; Salvatore, D	1
Accurso, F; Albers, G; Black, P; Brown, P; Buckingham, R; Cairns, A; Davis, SD; Graff, GR; Kerby, GS; Kloster, M; Mayer-Hamblett, N; Orenstein, D; Ramsey, BW; Retsch-Bogart, G; Rosenfeld, M	1
Deka, R; Hong, LT; King, JB; Liou, TG; Stevens, V; Young, DC	1
Arnold, K; Ernst, J; Fischer, D; Hartung, A; Klinger-Strobel, M; Makarewicz, O; Pletz, MW; Thamm, J	1
Crass, RL; Lodise, TP; Pai, MP	1
Bar-Yoseph, R; Bentur, L; Geffen, Y; Gur, M; Hakim, FH; Nir, V; Toukan, Y	1
Barnes, LA; Demirel, N; Gaillard, PR; Menk, JS; Regelmann, WE; Wey, AR	1
Barnaby, R; Gerber, SA; Hogan, DA; Jackson, AA; Koeppen, K; Stanton, BA	1
Bjarnsholt, T; Ciofu, O; Høiby, N; Jensen, PØ; Kolpen, M; Kragh, KN; Møller, SA	1
Claude, F; Hafen, GM; Rochat, I	1
Cogen, JD; Goss, CH; Nichols, DP; Nick, JA; Nick, SE; Russell, R; Saavedra, MT; Somayaji, R; Taylor-Cousar, JL	1
Klingel, M; Ratjen, F; Stanojevic, S; Tullis, E; Waters, V	1
Baravalle-Einaudi, M; Dubus, JC; Dupont, C; Le Pennec, D; Vecellio, L	1
Ascenzioni, F; Cavallaro, G; De Rocco, D; Di Domenico, EG; Giammona, G; Porsio, B; Santucci, R; Sardo, C	1
Crass, RL; Pai, MP	1
Arets, BGM; Heijerman, HGM; Janssens, HM; Nuijsink, M; Pullens, B; Touw, DJ; Uges, JWF; van der Wiel-Kooij, EC; van Maarseveen, EM; van Velzen, AJ; van Zanten, GA	1
Alkadri, J; Mostofian, F; Radhakrishnan, D; Tang, K; Thampi, N	1
Grimwood, K; Harun, SN; Hennig, S; Holford, NHG; Wainwright, CE	1
Marsot, A; Pasche, V; Thirion, DJG	1
Alghanem, SS; Thomson, AH; Touw, DJ	1
Hennig, S; Staatz, CE; Standing, JF; Thomson, AH	1
Alghanem, S; Paterson, I; Thomson, AH; Touw, DJ	1
Altamura, N; Borgatti, M; Breveglieri, G; Castaldo, R; Finotti, A; Gambari, R; Panin, GC; Salvatori, F; Zuccato, C	1
Amighi, K; Pilcer, G; Rosière, R; Sebti, T; Traina, K; Vanderbist, F	1
Cantón, R; Girón, RM; Lamas, A; Máiz, L; Mensa, J; Olveira, C; Pastor, D; Quintana, E	1
Daniels, T; Mills, N; Whitaker, P	1
Amighi, K; De Bueger, V; Pilcer, G; Sebti, T; Traina, K; Traore, H; Vanderbist, F	1
Kemper, AL; Young, DC; Zobell, JT	1
Angyalosi, G; Brockhaus, F; Chuchalin, AG; Galeva, I; Higgins, M; Konstan, MW; Piggott, S; Thomas, K	1
Börner, G; Denk, O; Eismann, C; Griese, M; Kappler, M; Keller, M; Mazurek, H; Schierholz, JM	1
Amin, RS; Carle, AC; Chini, BA; Fenchel, MC; Huang, B; McPhail, GL; Seid, M; VanDyke, RD	1
Elkin, EP; Emerson, J; Gibson, RL; Khan, U; Konstan, MW; Mayer-Hamblett, N; Morgan, W; Ramsey, BW; Retsch-Bogart, G; Rosenfeld, M; Thompson, V; Treggiari, MM; Wagener, J	1
Beegle, S; Butterfield, JM; Farkas, J; Lodise, TP; Pai, MP; Rosen, J	1
Coenye, T; Messiaen, AS; Nelis, H	1
Diamond, P; Elborn, JS; McCaughey, G; McKevitt, M; Tunney, MM	1
Elborn, JS; Gilpin, DF; Hoffman, LR; McCaughey, G; McKevitt, M; Schneiders, T; Tunney, MM	1
Angyalosi, G; Geller, DE; He, E; Higgins, M; Nasr, SZ; Piggott, S	1
Ampofo, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Waters, CD; Young, DC; Zobell, JT	1
Konstan, MW; Millar, SJ; Morgan, WJ; Pasta, DJ; Wagener, JS	1
Cios, D; DeGrado, JR; Greenwood, BC; Kubiak, DW; Szumita, PM	1
Mathew, JL; Ratjen, F; Stanojevic, S; Taylor, L; Waters, V	1
Pierart, F	1
McKeage, K	1
Al-Aloul, M; Nazareth, D; Walshaw, M	1
Cantrell, A; Carroll, C; Harnan, S; Mildred, M; Tappenden, P; Uttley, L	1
Brownlee, K; Cantrell, A; Harnan, S; Tappenden, P; Taylor, C; Uttley, L; Walshaw, M	1
Brownlee, K; Harnan, S; Mildred, M; Tappenden, P; Taylor, C; Uttley, L; Walshaw, M	1
Barraud, N; Buson, A; Jarolimek, W; Rice, SA	1
Ampofo, K; McCrory, BE; Olson, J; Sherwin, CM; Spigarelli, MG; Stockmann, C; Wisdom, M; Young, DC; Zobell, JT	1
Clark, P; Knight, H; Nolan, K	1
Antipkin, YG; Blanco-Aparicio, M; Bolbas, K; Chiron, R; Chuchalin, A; Cicirello, HG; Geidel, C; Kucerova, T; Mazurek, H; Santoro, D; Varoli, G; Zibellini, M	1
Chmiel, JF; Forssén, AV; Kim, SH; Moskowitz, SM; Nichols, DP; Nick, JA; Saavedra, MT; Saiman, L; Taylor-Cousar, JL	1
Cheney, J; Hennig, S; McKay, K; O'Brien, K; Stacey, S; Vidmar, S; Wainwright, CE	1
Gokdemir, Y; Karadag, B; Kargul, B; Mete, S; Peker, S	1
Beck, JF; Keller, PM; Koitschev, A; Koitschev, C; Mainz, JG; Michl, R; Riethmüller, J; Schädlich, K; Schelhorn-Neise, P; Schien, C; Wiedemann, B	1
Alicandro, G; Cariani, L; Claut, L; Colombo, C; Costantini, D; Defilippi, G; Di Cicco, M; Luca, N	1
Steinkamp, G	1
McColley, SA	1
Goss, CH; Quon, BS; Ramsey, BW	1
Prescott, WA	1
Barry, PJ; Jones, AM	1
Eustace, JA; Fleming, C; Harrison, MJ; Hickey, C; McCarthy, M; Murphy, DM; Plant, BJ; Shortt, C	1
Accurso, FJ; Ajayi, T; Barth, J; Branstrom, A; Bronsveld, I; De Boeck, K; Elborn, JS; Elfring, GL; Fajac, I; Kerem, E; Knoop, C; Konstan, MW; Malfroot, A; McColley, SA; Melotti, P; Peltz, SW; Quattrucci, S; Rietschel, E; Rosenbluth, DB; Rowe, SM; Sermet-Gaudelus, I; Spiegel, RJ; Walker, PA; Welch, EM; Wilschanski, M; Zeitlin, PL	1
Gąszczyk, G; Mazurek, H; Sands, D; Sapiejka, E	1
Fiel, SB	2
Berkhout, MC; de Kok, BM; Fokkens, WJ; Heijerman, HG; Touw, DJ; van Velzen, AJ	1
Deane, J; Denys, GA; Goering, RV; Locke, JB; Sahm, DF; Scharn, CR; Shaw, KJ; Zuill, DE	1
Bratton, DL; Burns, JL; Caceres, SM; Malcolm, KC; Moskowitz, SM; Nichols, DP; Nick, JA; Saavedra, MT; Taylor-Cousar, JL	1
Catal, F; Karadag, A	1
Arnold, C; Mainz, JG	1
Tappenden, P; Uttley, L	1
Bos, AC; Devadason, S; Janssens, HM; Mouton, JW; Tiddens, HA	1
LiPuma, JJ; Matukas, L; Ratjen, A; Speert, DP; Tullis, E; Waters, V; Wettlaufer, J; Yau, Y; Zlosnik, JE	1
Hennig, S; Holthouse, F; Staatz, CE	1
Abdelghany, SM; Deacon, J; Donnelly, RF; Elborn, JS; Gilmore, BF; Jones, DS; Kissenpfennig, A; Megaw, J; Quinn, DJ; Schmid, D; Scott, CJ; Taggart, CC	1
Dasenbrook, EC; Konstan, MW; VanDevanter, DR	1
Aaron, SD; Bell, SC; Conrad, D; Dudley, MN; Fischer, R; Flume, PA; Geller, DE; Kerem, E; Loutit, JS; Morgan, EE; Smyth, AR; Stuart Elborn, J; VanDevanter, DR	1
Elborn, JS; Shteinberg, M	1
Arslanov, DD; Cristescu, SM; Harren, FJ; Mandon, J; Merkus, PJ; Mouton, JW; Neerincx, AH; van Ingen, J	1
Heijerman, HG; Le Brun, PP; Shahbabai, P; Touw, DJ; Uges, JW; van Velzen, AJ	1
Cooper, R; Howe, R; Jenkins, R; Wootton, M	1
Parkins, MD; Somayaji, R	1
Hayes, D; Kopp, BT; Nicholson, L; Paul, G; Ramanathan, C; Tobias, J	1
Antoniu, S	1
Daines, CL; Farquharson, R; Higuchi, K; Schechter, MS; Trueman, D	1
Bielecki, P; Gocht, B; Häussler, S; Kasnitz, N; Komor, U; Moter, A; Pawar, V; Pils, MC; Rohde, M; Weiss, S	1
Farinde, A	1
Campbell, KC; Cooper, MD; Fox, DJ; Hargrove, TL; Meech, RP; Roberts, MH; Rybak, LP; Speil, CA; Verhulst, SJ; Yanik, SC	1
Jain, K; Knox, AJ; Koch, BC; Prayle, AP; Smyth, AR; Touw, DJ; Watson, A	1
Biondo, L; Brigg Turner, R; Elbarbry, F	1
Bay, C; Griffin, EF; Naimie, AA; O'Toole, GA; Price, KE	1
Beaudoin, T; Clark, S; Coburn, B; Guttman, DS; Hwang, DM; Smith, L; Vidya, P; Waters, V; Yau, YC	1
Beaudoin, T; Caraher, E; Kennedy, S; LiPuma, JJ; Speert, DP; Tullis, E; Waters, V; Yau, YC; Zlosnik, JE	1
Hebert, WP; Mastoridis, P; O'Toole, GA; Orazi, G; Price, KE; Ruoff, KL	1
Kotsimbos, T; Langan, KM; Peleg, AY	1
Beaudoin, T; LiPuma, JJ; Tom, SK; Waters, V; Yau, YC	1
Alonso, T; Ancochea, J; Cisneros, C; Garcia, J; Garcia-Castillo, E; Giron, RM; Gomez-Punter, RM; Marcos, C; Valenzuela, C; Vazquez-Espinosa, E; Zamora, E	1
Heuer, HE; Krippner, F; Merkel, N; Posselt, HG; Rietschel, E; Sieder, C; Staab, D; van Koningsbruggen-Rietschel, S; Ziegler, J	1
Bachiller, D; Esquisabel, A; Fleischer, A; Moreno-Sastre, M; Palomino, E; Pastor, M; Pedraz, JL; Sans, E; Viñas, M	1
Angyalosi, G; Debonnett, LM; Flume, PA; Galeva, I; Konstan, MW; Maykut, RJ; Wan, R	1
Baziard, G; El Hage, S; Furiga, A; Lajoie, B; Roques, C	1
Bos, AC; Heijerman, HG; Janssens, HM; Tiddens, HA; Touw, DJ; van Velzen, AJ	1
Cohen, F; Elborn, JS; Flume, PA; Loutit, J; VanDevanter, DR	1
Akkerman, OW; Alffenaar, JW; de Boer, AH; Frijlink, HW; Hagedoorn, P; Hoppentocht, M; Kerstjens, HA; van der Werf, TS	1
Gilchrist, FJ; Kitt, H; Lenney, W	1
Colombo, G; Crapper, J; Padroni, M; Phillips, G; Traini, D; Young, PM; Zhu, B	1
Metzger, NL; Peasah, SK; Staubes, BA; Walker, SD	1
Gomes, T; Juurlink, DN; Khuu, W; Mamdani, MM; Paterson, JM; Tadrous, M	1
Bresnik, M; Clancy, JP; Derchak, PA; Flume, PA; Lewis, SA; Ramsey, BW; Retsch-Bogart, GZ; Tullis, DE	1
Angyalosi, G; Cao, W; Debonnett, L; Sommerwerck, U; Viegas, A; Virella-Lowell, I	1
Fraser-Pitt, D; Lovie, E; Mercer, D; O'Neil, D; Robertson, J	1
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Bennett, MR; Clancy, JP; Dong, M; Downes, KJ; Fukuda, T; Goldstein, SL; Haffner, C; Vinks, AA	1
Elborn, JS; van der Ent, CK	1
Cavallaro, G; Craparo, EF; Cusimano, MG; Giammona, G; Porsio, B; Schillaci, D; Spigolon, D	1
Lazova, S; Miteva, D; Perenovska, P; Petrova, G; Strateva, T	1
Bratcher, PE; Caceres, SM; Chmiel, JF; Happoldt, CL; Malcolm, KC; Nichols, DP; Nick, JA; Saavedra, MT; Saiman, L; Taylor-Cousar, JL	1
Aslam, AA; Higgins, C; Sinha, IP; Southern, KW	1
Carroll, K; Cohen, DM; Cross, CP; Feeney, MP; Garinis, AC; Gold, JA; Hunter, LL; Keefe, DH; Putterman, DB; Srikanth, P; Steyger, PS	1
Beaudoin, T; Klingel, M; McDonald, N; Ratjen, F; Rizvi, L; Tom, SK; Tullis, E; Waters, V; Wettlaufer, J; Yau, Y	1
Iglewski, BH; Wagner, VE	1
George, AM; Iredell, J; Middleton, PG; Treerat, P; Widmer, F	1
Heijerman, HG; Kingma, H; Rijntjes, E; Scheenstra, RJ; Tavy, DL	1
Chan, J; Charron, M; Coates, AL; Green, M; Keller, M; Leung, K; Louca, E; Ratjen, F; Ribeiro, N; Tservistas, M	1
Konstan, MW; Mabie, JA; Mayer-Hamblett, N; Mink, DR; Moskowitz, SM; Pasta, DJ; Silva, SJ; Wagener, JS	1
Boer, AH; Brun, PP; Frijlink, HW; Heijerman, HG; Roldaan, AC; Touw, DJ; Westerman, EM	1
Devleeschouwer, MJ; El Manssouri, N; Macé, C; Traore, H; Tré-Hardy, M; Vanderbist, F	1
Kamin, W; Krämer, I; Lichtinghagen, R; Schwabe, A	1
Culumber, ZW; Purdy Drew, KR; Sanders, LK; Wong, GC; Zribi, O	1
Moreau-Marquis, S; O'Toole, GA; Stanton, BA	1
Etchebere, EC; Grotta, MB; Ribeiro, AF; Ribeiro, JD; Ribeiro, MA; Romanato, J	1
Boni, V; Braccini, G; Braggion, C; Ciuti, R; De Martino, M; Festini, F; Lori, I; Neri, AS; Pela, I; Taccetti, G; Zavataro, L	1
Ahern, JW; Corriveau, M; Lahiri, T; Van Meter, DJ	1
Bertram, C; Elborn, JS; Hodson, M	1
Grimwood, K; Kidd, TJ; Tweed, M	1
Church, AC; Foweraker, J; Parmer, J; Sivasothy, P	1
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Lamb, S; Ludgate, MW; Patel, D	1
Boer, AH; Frijlink, HW; Heijerman, HG; Rottier, BL; Sluyter, TS; van Erp, CJ	1
Emerson, J; Gibson, RL; Kronmal, RA; Mayer-Hamblett, N; Ramsey, BW; Retsch-Bogart, G; Rosenfeld, M; Treggiari, MM; Williams, J	1
Alipour, M; Azghani, AO; Halwani, M; Omri, A; Suntres, ZE	1
Heijerman, HG; Rijntjes, E; Scheenstra, RJ; Touw, DJ; Zuur, CL	1
Devleeschouwer, MJ; El Manssouri, N; Traore, H; Tré-Hardy, M; Vanderbist, F; Vaneechoutte, M	1
Amelina, E; Bianco, F; Chuchalin, A	1
Delaisi, B; Dominique, S; Hubert, D; Kho, P; Kovarik, JM; Leroy, S; Mely, L; Murris-Espin, M; Nove-Josserand, R	1
Angyalosi, G; Brockhaus, F; Ratjen, F	1
Ballmann, M; Claass, A; Doering, G; Franke, P; Junge, S; Riethmueller, J; Schroeter, TW; Stern, M; von Butler, R	1
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Gregori-Roig, P; Pantoja-Martínez, J; Valls-López, S; Yagüe-Muñoz, A	1
Bjarnsholt, T; Calum, H; Christensen, LD; Christophersen, L; Ciofu, O; Givskov, M; Hougen, HP; Høiby, N; Jensen, PØ; Molin, S; Moser, C; van Gennip, M	1
Ball, R; Brownlee, KG; Conway, SP; Denton, M; Duff, AJ; Lee, TW	1
Angyalosi, G; Kho, P; Munck, A; Ratjen, F	1
Nagel, JL; Prescott, WA	1
Bhatt, J; Smyth, AR	2
Coulthard, K; Doecke, C; Greville, H; Soulsby, N	1
Elborn, JS; Goldsmith, CE; Maeda, Y; Moore, JE; Rendall, JC	1
Burns, JL; Elliott, D; Hoffman, LR	1
Christodoulou, E; Eckhardt, BP; Nasr, SZ; Sakmar, E; Streetman, DS; Strouse, PJ	1
Bosomworth, M; Brownlee, KG; Conway, SP; Denton, M; Guy, EL; Lee, TW	1
Accurso, FJ; Harris, JK; Sagel, SD; Wagener, JS; Wagner, BD; Zemanick, ET	1
Smyth, AR	1
Griese, M; Hector, A; Kappler, M	1
Brown, R; Sacco, P; Woodward, TC; Zhang, J	1
Baquero, F; Cantón, R; del Campo, R; García-Castillo, M; Morosini, MI; Turrientes, MC; Zamora, J	1
Abele-Horn, M; Frosch, M; Hebestreit, H; Horn, S; Oesterlein, A; Radike, K; Schoen, C; Valenza, G	1
Prayle, A; Smyth, AR	1
Chermenskiĭ, AG; Gembitskaia, TE	1
Boyle, J; Elborn, JS; Hall, V; McKenna, KE; Tolland, JP	1
Edenborough, F; Kho, P; Kovarik, JM; Lenney, W	1
Adeboyeku, D; Hodson, ME; Jones, AL	1
Acton, JD; Amin, RS; Chima, A; Ednick, M; Fenchel, MC; McPhail, GL; Seid, M; VanDyke, R; Weiland, J	1
Döring, G; Herrmann, G; Høiby, N; Molin, S; Riethmüller, J; Song, Z; Ulrich, M; Wang, H; Wu, H; Yang, L	1
Angyalosi, G; Brockhaus, F; Geller, DE; Konstan, MW; Minić, P; Zhang, J	1
Abdelrahim, ME; Diot, P; Dubus, JC; Galle, J; Montharu, J; Vecellio, L	1
Angyalosi, G; Brockhaus, F; Chiron, R; Flume, PA; Geller, DE; He, E; Higgins, M; Kappler, M; Konstan, MW; Zhang, J	1
Neale, R; Rose, LM	1
Briesacher, BA; Fouayzi, H; Quittell, LM; Quittner, AL; Sacco, P; Saiman, L	1
Berlana, D; Jódar, R; Llop, JM; Manresa, F	1
Davis, GA; Feola, DJ; Hayes, D; Kuhn, RJ; Murphy, BS	1
Mitov, I; Petrova, G; Strateva, T	1
Cho, E; Davidson, AG; Lillquist, YP	1
Atenafu, E; Corey, M; Leahy, TR; Ratjen, F; Waters, V; Yau, YC	1
Appelbaum, PC; Beachel, L; Clark, C; Credito, K; Kosowska-Shick, K; McGhee, P; Pankuch, GA	1
Geller, DE; Heuerding, S; Weers, J	1
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Bilderback, A; Boyle, MP; Eakin, MN; Mogayzel, PJ; Riekert, KA	1
Knox, A; Smyth, A	1
Davis, GA; Flynn, JD; Hayes, D; Kuhn, RJ; Walsh, KA; Weant, KA	1
Hayes, D; Mansour, HM	1
Latremouille-Viau, D; Sawicki, GS; Shi, L; Signorovitch, JE; von Wartburg, M; Wu, EQ; Zhang, J	1
Burns, JL; Gibson, RL; Khan, U; Kronmal, RA; Mayer-Hamblett, N; Ramsey, BW; Retsch-Bogart, G; Rosenfeld, M; Treggiari, MM	1
Di Bonaventura, G; Di Primio, A; Fiscarelli, E; Gennaro, R; Guida, F; Pompilio, A; Pomponio, S; Scocchi, M	1
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Chang, CL; Kuhn, RJ; Stephenson, JJ; Wertz, DA; Zhang, J	1
Elborn, JS; Parkins, MD	1
Beck, JF; Mainz, JG; Michl, R; Pfister, W	1
Geller, DE; Kissner, DG; McColley, SA; McKevitt, M; Montgomery, AB; Moorehead, L; Rolfe, MW; Rosen, JM; Trapnell, BC	1
Elborn, JS; McCaughey, G; McKevitt, M; Tunney, MM	1
Martin, L; Rajendran, R; Ramage, G; Rinaldi, A; Smith, K; Walker, D	1
Ballmann, M; Geller, DE; Smyth, A	1
Bozkurt-Guzel, C; Gerceker, AA; Savage, PB	1
Geara, AS; Parikh, A; Rao, MK; Rekhtman, Y	1
Bianchini, E; Buzzetti, R; Campana, S; Cariani, L; Costantini, D; Taccetti, G; Trevisan, F; Zavataro, L	1
Fillaus, J; Florescu, DF; Florescu, MC; Lyden, E; Murphy, PJ	1
Abdolrasulnia, M; Debonnett, L; Glauser, TA; Nevins, PH; Riekert, KA; Salinas, GD; Williamson, JC; Zhang, J	1
Balp, MM; Kulich, K; Regnault, A; Viala-Danten, M	1
Anderson, G; Burns, JL; Emerson, J; Genatossio, A; McNamara, S; Moss, R; Rosenfeld, M; Ruddy, J	1
Beisty, J; Clough, D; Jones, A; Keevil, B; McKenna, D; Morris, J; Webb, K	1
Al-Khadra, ES; Barone, CP; Chau, KW; Colin, AA	1
Hewer, SL	1
Fothergill, JL; James, CE; Kirchner, S; Mowat, E; Winstanley, C; Wright, EA	1
Angyalosi, G; Balp, MM; Capkun-Niggli, G; Doering, G; Higashi, K; Jansen, JP; Littlewood, KJ; Tiddens, HA	1
Filkins, LM; Gifford, AH; Gross, MJ; Hampton, TH; Hogan, DA; Morrison, HG; O'Toole, GA; Paster, BJ; Sogin, ML	1
Boulanger, L; De Boeck, K; Proesmans, M; Verhaegen, J; Vermeulen, F	1
Griffin, EF; Moreau-Marquis, S; O'Toole, GA; Schwartzman, JD; Stanton, BA; Yu, Q	1
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Bell, SC; Goss, CH	1
Döring, G; Goldman, MH; Haliburn, C; Schuster, A	1
Acerbi, D; Annoni, O; Cicirello, H; Govoni, M; Poli, G; Ružička, J; Santoro, D	1
Jahnke, N; Remmington, T; Ryan, G	1
Ayyagari, R; Fan, L; Latremouille-Viau, D; Sawicki, GS; Shi, L; Signorovitch, JE; Swallow, E; Wu, EQ; Zhang, J	1
Bullington, WM; Flume, PA; Heh, JL; Stenbit, AE	1
Jamerson, PA; Wilson, K	1
Calero, C; Dapena, FJ; Lopez-Campos, JL; Quintana-Gallego, E	1
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Elphick, H; Evans, GS; Everard, ML; Jones, A; Pettitt, E	1
Geller, DE; Nardella, PA; Pitlick, WH; Ramsey, BW; Tracewell, WG	1
Nikolaizik, WH; Ratjen, F; Trociewicz, K	1
Govan, J	1
Alothman, GA; Alsaadi, MM; Coates, AL; Corey, M; Dupuis, A; Ho, BL; Ho, SL	1
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Aminimanizani, A; Beringer, PM; Jelliffe, RW; Kang, J; Shapiro, BJ; Tsang, L	1
Bitzan, MM; Hoffmann, IM; Iskandar, SS; Nagaraj, SK; Rubin, BK; Schechter, MS	1
Gallagher, CG; Govan, JR; Hodson, ME	1
Accurso, F; Burns, JL; Dovey, M; Emerson, J; Gibson, RL; Hamblett, N; Hiatt, P; Konstan, MW; McNamara, S; Moss, R; Ramsey, B; Retsch-Bogart, G; Rosenfeld, M; Wagener, J; Waltz, D; Wilmott, R; Yunker, A; Zeitlin, PL	1
Borel, B; Charara, O; Foucaud, P; Nathanson, S; Petitprez, P; Pin, I	1
Rothman, KJ; Wentworth, CE	1
Boyle, MP	1
Geller, DE; Rosenfeld, M; Waltz, DA; Wilmott, RW	1
Burns, JL; Fiel, SB; Mayer-Hamblett, N; Ramsey, B; Smith, AL	1
Dolovich, MB; Freitag, AP; Labiris, NR; Nahmias, C; Thompson, ML	1
Adriensen, B; Husson, MO; Loiez, C; Massoni-Cristante, S	1
Pitt, TL; Sparrow, M; Stefanidou, M; Warner, M	1
Jarvinen, AO; Martin, AJ; Nation, RL; Roberts, GW	1
Cheer, SM; Noble, S; Waugh, J	1
Brennan, AL; Geddes, DM	1
Scott, EM; Tunney, MM	1
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Ancochea, J; Antelo, C; Barrio, I; Beltrán, B; Cabanillas, J; Girón, RM; Máiz, L; Martínez, A; Martínez, MT; Prados, C; Salcedo, A	1
Cleveland, RH; Colin, AA; Slattery, DM; Zurakowski, D	1
Anbar, RD; Colin, AA; Lester, LA; Murphy, TD; Nasr, SZ; Nickerson, B; VanDevanter, DR	1
Connett, GJ; Jones, G; Nicholson, T; Struthers, SL	1
Smith, AL	1
Bowman, CM	1
Gallagher, CG; Hodson, ME	1
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Dennis, JH; Pieron, CA	1
Drummond, M; Iles, R; Legh-Smith, J; Prevost, A; Vowler, S	1
Coulthard, K; Lind, A; Madsen, V; Rasmussen, M	1
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Elborn, S; Moriarty, F; Tunney, M	1
Andrés, MT; Fierro, JF; Pérez, F; Viejo-Diaz, M	1
Lobue, PA	1
Gosset, P; Husson, MO; Turck, D; Wallaert, B; Wizla-Derambure, N	1
Horrevorts, AM; Jacobs, N; Mouton, JW; Tiddens, H	1
Chadwick, M; Davies, JC; Kerr, J; Kozlowska, W; Makhecha, S; Spencer, H; Webber, P	1
Campbell, P; Marshall, BC; Mayer-Hamblett, N; Saiman, L	1
Kidd, TJ; Middleton, PG; Williams, B	1
Alvarez, A; Baquero, F; Cantón, R; Cobos, N; de Gracia, J; García-Quetglas, E; Gartner, S; Honorato, J; Oliver, A; Salcedo, A	1
Baquero, F; Cantón, R; García-Castillo, M; Loza, E; Morosini, MI; Pérez-Vázquez, M	1
Al-Bakri, AG; Allison, DG; Gilbert, P	1
Alonzo, TA; Brumback, LC; Pepe, MS	1
Blumer, JL; Konstan, MW; Melnick, D; Saiman, L	1
Glass, S; Plant, ND; Spencer, DA	1
Elborn, JS; Field, TR; Tunney, MM; White, A	1
Bourget, C; Lafleur, L; Lagacé, J; Lapointe, JR; Mainville, S; Montplaisir, S	1
Balke, B; Häussler, S; Hogardt, M; Hoy, L; Schmoldt, S; Weissbrodt, H	1
Smyth, AR; Wood, DM	1
Patatanian, L	1
Kamin, W; Krämer, I; Schwabe, A	1
Bossuyt, X; Godding, V; Leal, T; Lebecque, P; Reychler, G; Zylberberg, K	1
Campana, S; Ciuti, R; De Martino, M; Festini, F; Repetto, T; Taccetti, G	1
Hyman-Taylor, P; Knox, A; Lewis, S; Mulheran, M; Smyth, A; Stableforth, D; Tan, KH	1
Adeboyeku, D; Hodson, ME; Scott, S	1
Bell, J; Conway, SP; Coulthard, KP; Peckham, DG; Smith, CA; Turnidge, J	1
Goss, CH; Kronmal, RA; Mayer-Hamblett, N; Ramsey, BW; Williams, J	1
Andrieu, V; Bosdure, E; Boulaméry, A; Clavel, A; Dubus, JC; Gorincour, G; Lanteaume, A; Luc, C; Sarles, J; Stremler-Lebel, N	1
Bosomworth, M; Clifton, I; Conway, SP; Etherington, C; Peckham, DG	1
Burkhardt, O; Derendorf, H; Kumar, V; Lehmann, C; Madabushi, R; Welte, T	1
Cranswick, N; Massie, J	1
Ratjen, F	1
Christodoulou, E; Eckhardt, BP; Gordon, D; Nasr, SZ; Sakmar, E; Strouse, PJ; Yu, X	1
Knox, AJ; Smyth, A; Touw, DJ	1
Hagerman, JK; Klepser, ME; Knechtel, SA	1
Anbar, RD; Awa, E; Santos, RP	1
Conrad, C; Geller, DE; Konstan, MW; Noonberg, SB; Smith, J	1
Korzeniewska, A; Stelmach, I; Stelmach, W	1
Atenafu, E; Bitnun, A; Dekker, A; Lam, W; Ratjen, F; Seto, W; Solomon, M; Tjon, J; Waters, V; Wong, C; Yau, Y	1
Accurso, FJ; Acton, J; Burns, JL; Chatfield, BA; Emerson, J; Gibson, RL; Hiatt, P; Konstan, MW; Mayer-Hamblett, N; McNamara, S; Moss, R; Ramsey, BW; Retsch-Bogart, G; Waltz, DA; Williams, J; Zeitlin, P	1
Southern, KW	1
Acerbi, D; Corrado, ME; Eichler, HG; Eichler, I; Pennini, R; Poli, G; Soliani Raschini, A	1
Antypkin, YG; Aryayev, NL; Lenoir, G; Miano, A; Monici Preti, PA; Moretti, P; Varoli, G; Zanda, M	1
Bartnicka, MT; Chuchalin, A; Csiszér, E; Gyurkovics, K; Kapranov, N; Mazurek, H; Monici Preti, PA; Sands, D; Varoli, G	1
Amighi, K; Blocklet, D; Goole, J; Knoop, C; Pilcer, G; Van Gansbeke, B; Vanderbist, F	1
Boyle, MP; Diener-West, M; Goss, CH; Lechtzin, N; Marshall, BC; Merlo, CA	1
Bauernfeind, A; Fehling, M; Griese, M; Kappler, M; Latzin, P; Reinhardt, D	1
Hasan, MA; Lange, CF	1
Elborn, JS; McElnay, JC; Moriarty, TF; Tunney, MM	1
Elborn, JS; Moriarty, TF; Tunney, MM	1
Hennig, S; Kirkpatrick, CM; Norris, R	1
Brand, P; Dopfer, R; Häussermann, S; Hunger, T; Meyer, T; Müllinger, B; Scheuch, G; Siekmeier, R	1
Anderson, GG; Moreau-Marquis, S; O'Toole, GA; Stanton, BA	1
Devleeschouwer, MJ; Traore, H; Tré-Hardy, M; Vanderbist, F	1
Duh, MS; Sacco, P; Toy, EL; Weiner, JR	1
Dodd, ME; Jones, AM; Webb, AK; Weidmann, A	1
Anderson, GG; Bomberger, JM; Moreau-Marquis, S; O'Toole, GA; Stanton, BA; Swiatecka-Urban, A; Ye, S	1
Anderson, GJ; Lamont, IL; Reid, DW	1
Fitzpatrick, SB; Rosenstein, BJ	1
Goldmann, DA; Matthews, WJ; McLaughlin, FJ; Murphy, P; Strieder, DJ; Sullivan, B; Taneja, A	1
Goldmann, DA; Matthews, WJ; McLaughlin, FJ; Strieder, DJ; Sullivan, B	1
Alfredson, H; Ericsson, A; Malmborg, AS; Strandvik, B	1
Christensen, HO; Høiby, N; Koch, C; Møller, AF; Møller, S; Permin, H	1
Fleming, PC; Gold, R; Isles, A; Jin, E; Levison, H	1
Connor, PJ; David, TJ; Phillips, BM	1
Koup, JR; Levy, J; Ramsey, B; Smith, AL; Williams-Warren, J	1
Batten, JC; Hodson, ME; Wingfield, HJ	1
Heilesen, AM; Høiby, N; Koch, C; Permin, H	1
Bryan, LE; Godfrey, AJ; Rabin, HR	1
Eriksen, KR; Feddersen, C; Flensborg, EW; Høiby, N; Møller, NE; Norn, S; Rosendal, K; Schiøtz, PO; Skov, PS	1
Hoogkamp-Korstanje, JA; van der Laag, J	1
Flensborg, EW; Høiby, N; Szaff, M	1
Alfredsson, H; Malmborg, AS; Strandvik, B	1
Boat, TF; Cheng, PW; Powell, SH; Reed, MD; Stern, RC; Vermeulen, MW	1
Kluge, RM	1
Marks, MI; Scribner, RK; Tarpay, MM; Weber, AH; Welch, DF	1
Baran, D; Klastersky, J; Levy, J	1
Antonelli, M; Crifo, S; Gagliardi, M; Lucarelli, N; Marcolini, P	1
Bloxham, DD; Cash, HA; DiScenna, AO; Groden, DL; Grossniklaus, DA; Jacobs, MR; Klinger, JD; Luthe, MA; Powell, SH; Stern, RC; Thompson, WL	1
Kramer, RI; McCracken, GH; Nelson, JD; Prestidge, CB; Wientzen, R	1
Fan, L; Kelly, HB; Menendez, R; Murphy, S	1
Leff, RD; Roberts, RJ	1
Anderson, CM; George, RH; Healing, DE; Martin, AJ; Smalley, CA	1
Berger, A; Hunt, BE; Ramsey, B; Smith, AL; Weber, A	1
Davidson, TM; Light, M; Mitchell, M; Murphy, C; Smith, C	1
Beaulieu, R; Dessanges, JF; Farinotti, R; Faurisson, F; Grimfeld, A; Kitzis, MD; Lefebvre, JP; Peytavin, G; Sautegeau, A	1
Boissinot, E; Diot, P; Le Pape, A; Lemarié, E	1
Ciofu, O; Giwercman, B; Høiby, N; Pedersen, SS	1
Bakker, W; Heijerman, HG; Hermans, J; Touw, DJ; Vinks, AA	1
Cooney, GF; Fiel, SB; Lum, BL; Tomaselli, M	1
Covert, DS; Ramsey, B; Smith, A; Weber, A; Williams-Warren, J	1
Harris, CE; Wilmott, RW	1
Carswell, F; Davies, ER; Eastman, C; Mukhopadhyay, S; Palmer, M; Staddon, GE	1
Ashby, BL; Stern, DH	1
Bakker, W; Heijerman, HG; Touw, DJ; Vinks, AA	2
Baer, S; Blanshard, J; Carswell, F; Coleman, M; Mukhopadhyay, S	1
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Corti, G; Paradisi, F	1
Featherstone, C	1
Beaulieu, R; Dessanges, JF; Farinotti, R; Faurisson, F; Grimfeld, A; Kitzis, MD; Lefevre, JP; Peytavin, G; Sautegeau, A	1
Hickey, B; Hooper, RE; Ioannides-Demos, LL; Li, SC; McLean, AJ; Spicer, WJ; Williams, TJ; Wood, PJ	1
Guglielmo, BJ; Quan, LA; Stulbarg, MS	1
Jenni-Galović, V; Nikolaizik, WH; Schöni, MH	1
Barclay, ML; Begg, EJ; Chambers, ST; Grimwood, K; Pattemore, PK; Thornley, PE	1
Bakker, W; Heijerman, HG; Jacobs, F; Town, DJ; Vinks, AA	1
Bakker, W; Briemer, DD; Brimicombe, RW; Heijerman, HG; Jacobs, FA; Touw, DJ	1
Church, DA; Echols, RM; Haverstock, DC; Kanga, JF; Kuhn, RJ; Painter, BG; Perroncel, RY; Rubio, TT; Spohn, WA; Stevens, JC; Thurberg, BE	1
Eisenberg, J; Montgomery, AB; Pepe, M; Ramsey, BW; Smith, AL; Vasiliev, M; Williams-Warren, J	1
Coates, AL; Kelemen, S; MacDonald, J; MacNeish, CF; Meisner, D; Thibert, R; Vadas, E	1
Bowler, SD; McCormack, JG; Nolan, PJ; Wolter, JM	1
Hampel, BJ; Nousia-Arvanitakis, S; Richard, DA; Schaad, UB; Sollich, V; Sommerauer, B	1
Ategbo, S; Druon, D; Elian, JC; Farriaux, JP; Gottrand, F; Launay, V; Loeuille, GA; Turck, D; Vic, P	1
Neef, C; Touw, DJ; Vinks, AA	1
Aebischer, CC; Mordasini, C; Schoch, OD	1
Barson, WJ; Bates, RD; Cox, S; Jones, JW; McCoy, K; Nahata, MC; Young, G	1
Paparella, MM; Schachern, PA; Sone, M	1
Nightingale, SL	1
Bauernfeind, A; Döring, G; Przyklenk, B; Ratjen, F; Steinkamp, G; von der Hardt, H; Wiesemann, HG	1
Homnick, DN; Katbamna, B; Marks, JH	1
Burns, JL; Clausen, CR; Emerson, J; Krzewinski, J; Louden, L; Ramsey, BW; Stapp, JR; Yim, DL	1
Adams, JP; Conway, SP; Wilson, C	1
Bragonier, R; Brown, NM	1
Arrouet-Lagande, C; Ategbo, S; Deschildre, A; Druon, D; Husson, MO; Launay, V; Loeuille, GA; Sardet, A; Turck, D; Vic, P	1
Ategbo, S; Canis, F; Husson, MO; Trivier, D; Turck, D; Vic, P	1
Borowitz, D; Bowman, CM; Marshall, BC; Marshall, S; Montgomery, AB; Otto, KL; Pepe, MS; Quan, JM; Ramsey, BW; Smith, AL; Vasiljev-K, M; Williams-Warren, J	1
Bingen, E; Bonacorsi, S; Fitoussi, F; Lhopital, S	1
Doershuk, C; Goldmann, D; Gore, E; Hilman, B; Marks, M; Moss, R; Ramsey, B; Redding, G; Rubio, T; Smith, AL; Williams-Warren, J; Wilmott, R; Wilson, HD; Yogev, R	1
Albers, GM; Burns, JL; Garber, RL; Montgomery, AB; Otto, KL; Quan, JM; Ramsey, BW; Shawar, RM; Smith, AL; Van Dalfsen, JM	1
Bowler, SD; McCormack, JG; Wolter, JM	1
Dupuis, RE; Sredzienski, ES	1
Po, AL; Scott, EM; Tariq, VN; Wu, YL	2
Hazinski, TA	2
Akbar, A; English, MW; Nyamugunduru, G; Rees, JH; Spencer, DA; Weller, PH	1
Campbell, PW; Saiman, L	1
de Boer, AH; Frijlink, HW; Gjaltema, D; Hagedoorn, P; Heijerman, HG; Le Brun, PP	2
Hjelte, L; Jorulf, H; Lagerstrand, L	1
Faris, M; O'Riordan, T	1
Beringer, PM	1
Burns, JL; Clausen, CR; Garber, RL; MacLeod, DL; Shawar, RM; Stapp, JR; Tanaka, SK	1
Coulter, SN; Folger, KR; Hickey, MJ; Nguyen, LY; Shawar, RM; Sherman, DR; Stover, CK; Warrener, P; Westbrock-Wadman, S; Zhu, YQ	1
Elidemir, O; Maciejewski, SR; Oermann, CM	1
Birnbaum, H; Greenberg, P; LeLorier, J; Perreault, S; Sheehy, O	1
Burns, JL; Dirk, JE; Garber, RL; Lin, BB; Lockwood, LG; MacLeod, DL; Miller, GH; Nelson, LE; Shawar, RM	1
Beringer, PM; Jelliffe, RW; Shapiro, BJ; Vinks, AA	1
Lands, LC; Ramagopal, M	1
Bärmeier, H; Bartel, K; Böwing, B; Habash, T; Heininger, U; Lugauer, S; Schoerner, C; Unsal, M	1
Coates, AL; Dinh, L; Gagnon, S; Ho, SL; Lands, LC; MacNeish, CF; Rollin, T	1
Jones, J; Prober, CG; Walson, PD	1
Alothman, GA; Gysin, C; Papsin, BC	1
Denton, M; Kerr, KG; Mooney, L	1
Robinson, P	1
Allen, PD; Coates, AL; Ho, SL; Lands, LC; MacNeish, CF	1
Papapella, MM; Schachern, PA; Sone, M; Zheng, Y	1
Baghurst, PA; Colebatch, KA; Coulthard, KP; Hansman, D; Holmes, M; Jarvinen, A; Kennedy, D; Linke, RJ; Martin, A; Martin, AJ; Master, V; Onishko, CR; Parsons, DW; Roberts, GW; Roberts, ME	1
Doull, IJ	1
Burr, S; Degg, C; Morgan, DW; Mulheran, M; Stableforth, DE	1
Moss, RB	4
LiPuma, JJ	1
Emerson, J; Montgomery, AB; Pepe, M; Ramsey, B; Rosenfeld, M; Smith, A; Williams-Warren, J	1
Bingen, E; Bonacorsi, S; Brahimi, N; Gérardin, M; Lebourgeois, M; Mariani-Kurkdjian, P; Munck, A; Navarro, J	1
Nahata, MC; Pai, VB	1
Döring, G; Nikolaizik, WH; Ratjen, F	1
Borowitz, D; Burns, JL; Emerson, J; Gibson, R; Konstan, MW; McCoyd, KS; McNamara, S; Montgomery, AB; Ramsey, B; Retsch-Bogart, G; Rosenfeld, M; Shell, R; Vicini, P; Wilmott, RW	1
Burns, JL; Phelps, C; Stapp, JR; Stewart, P; Van Dalfsen, JM	1
Hyman-Tylor, P; Knox, A; Mulheran, M; Smyth, A; Tan, KH	1
Hubert, D; Sermet-Gaudelus, I; Turck, D	1
Schülin, T	1
Bogle, S; Caldwell, NA; Conway, SP; Etherington, C; Setchfield, N; Whitehead, A	1
Campana, S; Farina, S; Procopio, E; Repetto, T; Taccetti, G	1
Assael, BM; Candusso, M; Faraguna, D; Marchetti, F	1
Griese, M; Müller, I; Reinhardt, D	1
Flume, P; Klepser, ME	1
Kuhn, RJ	1
Flume, PA; Kuhn, RJ	1
Buu, A; Quittner, AL	1
Borowitz, D; Cimino, M; Simon, D	1
Hurwitz, ME; Nasr, SZ; Spigarelli, MG	1
Marino, JT	1
Hyman-Taylor, P; Knox, A; Mulheran, M; Smyth, A; Tan, KH	1
Burns, JL; Graff, GR	1
Fyfe, JA; Govan, JR	1
Pennington, JE	1
Friis, B	1
Boxerbaum, B; Demko, CA; Kuchenbrod, PJ; Stern, RC; Thomassen, MJ	1
Neu, HC; Parry, MF	2
Hoogkamp-Korstanje, JA; Westerdaal, NA	1
Bruns, WT; Davis, SD	1
Bender, SW; Knothe, H; Paporisz, U; Posselt, HG; Ristow, W; Röser, D; Wönne, R	2
Abramson, AL; Forman-Franco, B; Gorvoy, JD; Stein, T	1
Kulczycki, LL; Wientzen, R	1
Bak-Pedersen, K; Friis, B; Jensen, K; Larsen, PK; Thomsen, J	1
Friis, B; Thomsen, J	2
Crozier, DN; Khan, SR	1
McCrae, WM	1
Hanson, EJ; McCrae, WM; Raeburn, JA	1
Dyke, JW; Hay, MB; Kumar, A; Maier, GA	1
Boudreau, RJ; Budd, JR; duCret, RP; Kuni, CC; Regelmann, WE	1
Greene, LM; Harwood, IR; Kozakowski-Koch, JA; Rasor, JS	1
Bowes, G; Hooper, RE; Ioannides-Demos, LL; Li, SC; McLean, AJ; Spelman, DW; Spicer, WJ; Tong, N	1
Cooper, JA; Cowan, RG; Lepow, M; Mayer, D; Winnie, GB; Witson, J	1
Chua, HL; Collis, GG; Le Souëf, PN	1
Clawson, CC; Elliott, GR; Regelmann, WE; Warwick, WJ	1
Ansorg, R; Müller, KD; Wiora, J	1
Agueda, L; Bertrou, A; Chabanon, G; Henry, S; Marty, N	1
Bakhache, P; Chivet, C; Douchain, F; Houdas, S; Lebas, L; Pautard, JC	1
Semsarian, C	1
Lieberman, J; Schwartzman, MN	1
Knowles, MR; Pleasants, RA; Waltner, WE; Williams, DM	1
Albus, A; Döring, G; Gappa, M; Potel, J; Steinkamp, G; Tümmler, B; von der Hardt, H	1
Corey, M; Gold, R; Levison, H; MacLusky, IB	1
De Boeck, K; Eggermont, E; Smet, M	1
Gore, EJ; Hack, B; Hedges, DL; Ramsey, BW; Redding, GJ; Smith, AL; Weber, A; Williams-Warren, J	1
Malottke, R; Steinkamp, G; Tümmler, B; von der Hardt, H	1
Alhadeff, JA; Guman-Wignot, TM; Holsclaw, DS; Kaufman, J; Schmoyer, IR	1
Ehrich, JH; Gröne, HJ; Lütge, M; Schulz-Baldes, JG; Steinkamp, G; Wurster, U	1
Brown, AL; Jiménez, JF; Kearns, GL; Warren, RH	1
Filliat, M; Lhermitte, M; Ramphal, R; Roussel, P	1
Høiby, N; Koch, C; Pedersen, SS; Rosendal, K	1
Escalona, L; Goldmann, D; L'Heureux, C; Macone, A; Maduri-Traczewski, M	1
Morgan, JR; Paull, A	1
Rubio, TT; Shapiro, C	1
Bentzon, MW; Høiby, N; Jensen, T; Koch, C; Pedersen, SS; Pressler, T; Rosdahl, VT	1
Bosso, JA; Matsen, JM; Saxon, BA	1
Bryan, LE; Chamberland, S; Godfrey, AJ; Ogunariwo, J; Rabin, HR; Schryvers, AB	1
Black, PG; Bosso, JA	1
Black, PG; Herbst, JJ; Jennison, K; Kane, RE; Wood, C	1
Andreasen, JJ; Lester, A	1
Kim, YD; Levine, MR; Witt, W	1
Gappa, M; Steinkamp, G; Tümmler, B; von der Hardt, H	1
Bosso, JA; Walker, KB	1
Carswell, F; Cook, DA; Speller, DC; Ward, C	1
Aronoff, SC; Cohn, RC; Jacobs, M	1
Delage, G; Desautels, L; Lamarre, A; Lapierre, JG; Lasalle, R; Legault, S; Masson, P; Spier, S	1
Black, P; Blumer, J; Craft, JC; Halsey, NA; McCarty, JM; Tilden, SJ; Waring, W	1
Flensborg, EW; Høiby, N; Jensen, T; Koch, C; Pedersen, SS	1
Friis-Møller, A; Høiby, N; Koch, C; Pedersen, M; Pressler, T; Stenvang Pedersen, S	1
Black, PG; Bosso, JA; Matsen, JM	1
Rubio, TT	1
Davidson, S; Nakatomi, M; Neu, HC; Ores, C; Scully, BE	1
Horner, GW; Stempel, DA	1
Jensen, T; Osterhammel, D; Osterhammel, P; Pedersen, SS	1
Fraser, GL	1
de Witte, J; Degener, JE; Driessen, O; Dzoljic-Danilovic, G; Hop, WC; Horrevorts, AM; Kerrebijn, KF; Michel, MF	1
Commissaris, RL; Hsu, MC; Massoud, N; Munzenberger, PJ	1
Earl, HS; Sullivan, TJ	1
Brasfield, DM; Jewett, CV; Ledbetter, J; Lyrene, RK; Tiller, RE	1
Conway, SP; Littlewood, JM; Miller, MG; Ramsden, C	1
Grassi, C	1
Aronoff, SC; Klinger, JD	1
Duncan, DE; Habbick, BF; Komiyama, K; Liepert, DJ; Tynan, JJ	1
Davis, RL; Levy, J; Mendelman, PM; Ramsey, B; Smith, AL; Weber, A	1
Degener, JE; Driessen, O; Dzoljic-Danilovic, G; Hermans, J; Horrevorts, AM; Kerrebijn, KF; Michel, MF	1
Alexander, JM; Chrystyn, H	1
Corbin, RP; Fraser, GL; Grimes, GR; Valenti, AJ	1

Reviews

75 review(s) available for tobramycin and Cystic Fibrosis

Article	Year
The use of tobramycin for Pseudomonas aeruginosa: a review. Expert review of respiratory medicine, 2022, Volume: 16, Issue:5 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Lung; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin	2022
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis. The Cochrane database of systematic reviews, 2022, 08-01, Volume: 8 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Lung; Quality of Life; Randomized Controlled Trials as Topic; Tobramycin	2022
Inhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis. The Cochrane database of systematic reviews, 2022, Nov-14, Volume: 11 Topics: Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Child; Child, Preschool; Cystic Fibrosis; Humans; Lysine; Middle Aged; Quality of Life; Randomized Controlled Trials as Topic; Tobramycin; Young Adult	2022
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. The Cochrane database of systematic reviews, 2023, 06-02, Volume: 6 Topics: Anti-Bacterial Agents; Azithromycin; Ceftazidime; Child; Child, Preschool; Ciprofloxacin; Colistin; Cystic Fibrosis; Humans; Infant; Monobactams; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2023
Nebuliser systems for drug delivery in cystic fibrosis. The Cochrane database of systematic reviews, 2023, 11-09, Volume: 11 Topics: Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Respiratory Aerosols and Droplets; Saline Solution, Hypertonic; Tobramycin	2023
Treatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis. The Cochrane database of systematic reviews, 2019, 12-17, Volume: 12 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Forced Expiratory Volume; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Randomized Controlled Trials as Topic; Recurrence; Secondary Prevention; Tobramycin	2019
Aminoglycoside dosing and monitoring for Pseudomonas aeruginosa during acute pulmonary exacerbations in cystic fibrosis. Pediatric pulmonology, 2021, Volume: 56, Issue:12 Topics: Aminoglycosides; Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2021
Evaluating the Impact of Education on Pharmacist Tobramycin Dose Recommendations for Cystic Fibrosis and a Review of Perceptions on Pharmacist-Led Charting. Journal of pharmacy practice, 2022, Volume: 35, Issue:6 Topics: Cross-Sectional Studies; Cystic Fibrosis; Humans; Pharmacists; Retrospective Studies; Tobramycin	2022
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. The Cochrane database of systematic reviews, 2017, 03-27, Volume: 3 Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Body Mass Index; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Injections, Intravenous; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Vital Capacity; Young Adult	2017
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. The Cochrane database of systematic reviews, 2017, 04-25, Volume: 4 Topics: Administration, Inhalation; Administration, Oral; Adult; Anti-Bacterial Agents; Child; Ciprofloxacin; Colistin; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory System; Tobramycin	2017
Tobramycin inhalation powder for the treatment of pulmonary Pseudomonas aeruginosa infection in patients with cystic fibrosis: a review based on clinical evidence. Therapeutic advances in respiratory disease, 2017, Volume: 11, Issue:5 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Medication Adherence; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin	2017
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis. The Cochrane database of systematic reviews, 2018, 10-30, Volume: 10 Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Cystic Fibrosis; Disease Progression; Forced Expiratory Volume; Humans; Injections, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Ticarcillin; Tobramycin	2018
Population pharmacokinetics of tobramycin in patients with and without cystic fibrosis. Clinical pharmacokinetics, 2013, Volume: 52, Issue:4 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Models, Biological; Models, Statistical; Multicenter Studies as Topic; Predictive Value of Tests; Sex Factors; Tissue Distribution; Tobramycin; Young Adult	2013
Inhaled antibiotics for the treatment of chronic bronchopulmonary Pseudomonas aeruginosa infection in cystic fibrosis: systematic review of randomised controlled trials. Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:9 Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Colistin; Cystic Fibrosis; Humans; Lung Diseases; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2013
Nebuliser systems for drug delivery in cystic fibrosis. The Cochrane database of systematic reviews, 2013, Apr-30, Issue:4 Topics: Aerosols; Albuterol; Anti-Bacterial Agents; Bronchodilator Agents; Carbenicillin; Colistin; Cromolyn Sodium; Cystic Fibrosis; Deoxyribonuclease I; Drug Delivery Systems; Humans; Medication Adherence; Nebulizers and Vaporizers; Randomized Controlled Trials as Topic; Recombinant Proteins; Saline Solution, Hypertonic; Tobramycin	2013
Tobramycin inhalation powder (Tobi Podhaler) for cystic fibrosis. The Medical letter on drugs and therapeutics, 2013, Jun-24, Volume: 55, Issue:1419 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Child, Preschool; Clinical Trials as Topic; Costs and Cost Analysis; Cystic Fibrosis; Drug Interactions; Female; Forced Expiratory Volume; Humans; Male; Nebulizers and Vaporizers; Powders; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Young Adult	2013
Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: V. Aminoglycosides. Pediatric pulmonology, 2013, Volume: 48, Issue:11 Topics: Adult; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Child; Cystic Fibrosis; Disease Progression; Gentamicins; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2013
[TOBI Podhaler for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis patients]. Revue medicale de Liege, 2013, Volume: 68, Issue:9 Topics: Administration, Inhalation; Anti-Bacterial Agents; Chronic Disease; Clinical Trials as Topic; Cystic Fibrosis; Dry Powder Inhalers; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2013
Tobramycin inhalation powder: a review of its use in the treatment of chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis. Drugs, 2013, Volume: 73, Issue:16 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2013
Colistimethate sodium powder and tobramycin powder for inhalation for the treatment of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis: systematic review and economic model. Health technology assessment (Winchester, England), 2013, Volume: 17, Issue:56 Topics: Administration, Inhalation; Child; Colistin; Cost-Benefit Analysis; Cystic Fibrosis; Disease Progression; Humans; Outcome Assessment, Health Care; Pseudomonas aeruginosa; Pseudomonas Infections; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Therapeutic Equivalency; Tobramycin; United Kingdom	2013
Systematic review of the dry powder inhalers colistimethate sodium and tobramycin in cystic fibrosis. European respiratory review : an official journal of the European Respiratory Society, 2013, Volume: 22, Issue:130 Topics: Administration, Inhalation; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Disease Progression; Dry Powder Inhalers; Evidence-Based Medicine; Forced Expiratory Volume; Humans; Lung; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Research Design; Time Factors; Tobramycin; Treatment Outcome	2013
[Dry powder inhalers in cystic fibrosis]. Pneumologie (Stuttgart, Germany), 2014, Volume: 68, Issue:6 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Diuretics, Osmotic; Drug Compounding; Dry Powder Inhalers; Humans; Mannitol; Powders; Pseudomonas Infections; Tobramycin	2014
Inhaled antibiotics for lower airway infections. Annals of the American Thoracic Society, 2014, Volume: 11, Issue:3 Topics: Administration, Inhalation; Amikacin; Amphotericin B; Anti-Bacterial Agents; Aztreonam; Ceftazidime; Colistin; Cystic Fibrosis; Gentamicins; Humans; Nebulizers and Vaporizers; Respiratory Tract Infections; Tobramycin	2014
Aerosolized antibiotics in cystic fibrosis: an update. Expert review of respiratory medicine, 2014, Volume: 8, Issue:3 Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Aztreonam; Colistin; Cystic Fibrosis; Equipment Design; Humans; Levofloxacin; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2014
Dry powder inhalers in cystic fibrosis: same old drugs but different benefits? Current opinion in pulmonary medicine, 2014, Volume: 20, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Colistin; Cost-Benefit Analysis; Cystic Fibrosis; Dry Powder Inhalers; Humans; Medication Adherence; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2014
Inhaled antibiotics: dry or wet? The European respiratory journal, 2014, Volume: 44, Issue:5 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Aztreonam; Colistin; Cystic Fibrosis; Disease Progression; Dry Powder Inhalers; Humans; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Tobramycin	2014
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. The Cochrane database of systematic reviews, 2014, Nov-10, Issue:11 Topics: Administration, Inhalation; Administration, Oral; Adult; Anti-Bacterial Agents; Child; Ciprofloxacin; Colistin; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2014
Use of inhaled tobramycin in cystic fibrosis. Advances in therapy, 2015, Volume: 32, Issue:1 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Dry Powder Inhalers; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Respiratory Function Tests; Tobramycin; Treatment Outcome	2015
Tobramycin inhalation powder: an efficient and efficacious therapy for the treatment of Pseudomonas aeruginosa infection in cystic fibrosis. Therapeutic delivery, 2015, Volume: 6, Issue:2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Drug Delivery Systems; Dry Powder Inhalers; Humans; Medication Adherence; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Technology, Pharmaceutical; Tobramycin	2015
Managing Pseudomonas aeruginosa respiratory infections in cystic fibrosis. Current opinion in infectious diseases, 2015, Volume: 28, Issue:6 Topics: Administration, Inhalation; Administration, Oral; Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Fungal; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	2015
Tobramycin inhalation powder (TOBI Podhaler) for the treatment of lung infection in patients with cystic fibrosis. Expert review of anti-infective therapy, 2016, Volume: 14, Issue:1 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Dry Powder Inhalers; Humans; Lung; Opportunistic Infections; Prognosis; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2016
Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic fibrosis. The Cochrane database of systematic reviews, 2017, 01-19, Volume: 1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Codon, Nonsense; Cystic Fibrosis; Disease Progression; Female; Humans; Male; Middle Aged; Oxadiazoles; Quality of Life; Randomized Controlled Trials as Topic; Tobramycin	2017
P. aeruginosa Biofilms in CF Infection. Clinical reviews in allergy & immunology, 2008, Volume: 35, Issue:3 Topics: Animals; Azithromycin; Biofilms; Cystic Fibrosis; DNA, Bacterial; Gene Expression Regulation, Bacterial; Humans; Immunity, Mucosal; Immunocompromised Host; Lung; Opportunistic Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Tobramycin	2008
Mediastinal abscess after lung transplantation secondary to Burkholderia gladioli infection. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:5 Topics: Abscess; Adult; Anti-Bacterial Agents; Burkholderia gladioli; Burkholderia Infections; Combined Modality Therapy; Cystic Fibrosis; Diagnosis, Differential; Drainage; Drug Therapy, Combination; Humans; Infusions, Intravenous; Lung Transplantation; Male; Mediastinal Diseases; Meropenem; Opportunistic Infections; Postoperative Complications; Thienamycins; Tobramycin; Tomography, X-Ray Computed	2009
Tobramycin for inhalation in cystic fibrosis: Beyond respiratory improvements. Pulmonary pharmacology & therapeutics, 2009, Volume: 22, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Nutritional Status; Patient Compliance; Pseudomonas Infections; Quality of Life; Respiratory Function Tests; Tobramycin	2009
Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: a review. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2009, Volume: 8, Issue:6 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2009
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4 Topics: Administration, Inhalation; Administration, Oral; Adult; Anti-Bacterial Agents; Child; Ciprofloxacin; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2009
Extended-interval once-daily dosing of aminoglycosides in adult and pediatric patients with cystic fibrosis. Pharmacotherapy, 2010, Volume: 30, Issue:1 Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Child; Clinical Trials as Topic; Cystic Fibrosis; Drug Administration Schedule; Drug Monitoring; Humans; Middle Aged; Respiratory Tract Infections; Tobramycin; Treatment Outcome; Young Adult	2010
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. The Cochrane database of systematic reviews, 2010, Jan-20, Issue:1 Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Child; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Injections, Intravenous; Lung Diseases; Male; Randomized Controlled Trials as Topic; Tobramycin; Vital Capacity	2010
Aminoglycoside use in cystic fibrosis: therapeutic strategies and toxicity. Current opinion in pulmonary medicine, 2010, Volume: 16, Issue:6 Topics: Acute Kidney Injury; Aminoglycosides; Cystic Fibrosis; Dose-Response Relationship, Drug; Gentamicins; Humans; Tobramycin	2010
[Use of inhaled tobramycin in patients with cystic fibrosis]. Terapevticheskii arkhiv, 2010, Volume: 82, Issue:8 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Treatment Outcome	2010
Eradication of Pseudomonas aeruginosa in an adult patient with cystic fibrosis. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011, Feb-15, Volume: 68, Issue:4 Topics: Adult; Anti-Infective Agents; Cefepime; Cephalosporins; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2011
Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere™ technology. Journal of aerosol medicine and pulmonary drug delivery, 2011, Volume: 24, Issue:4 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Drug Delivery Systems; Drug Design; Dry Powder Inhalers; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2011
Tobramycin Inhalation Powder™: a novel drug delivery system for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis. Expert review of respiratory medicine, 2011, Volume: 5, Issue:5 Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Cystic Fibrosis; Dry Powder Inhalers; Humans; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Tobramycin; Treatment Outcome	2011
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis. The Cochrane database of systematic reviews, 2012, Feb-15, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intravenous; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin; Young Adult	2012
Inhaled antibiotics in cystic fibrosis: what's new? Journal of the Royal Society of Medicine, 2012, Volume: 105 Suppl 2 Topics: Administration, Inhalation; Adolescent; Amikacin; Anti-Bacterial Agents; Aztreonam; Child; Child, Preschool; Ciprofloxacin; Clinical Trials, Phase III as Topic; Cystic Fibrosis; Female; Follow-Up Studies; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Incidence; Infant; Male; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Survival Rate; Tobramycin; Treatment Outcome	2012
A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012, Volume: 11, Issue:5 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Load; Bayes Theorem; Biological Availability; Chronic Disease; Colistin; Cystic Fibrosis; Disease Progression; Female; Forced Expiratory Volume; Humans; Information Services; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2012
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis. The Cochrane database of systematic reviews, 2012, Dec-12, Volume: 12 Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Carbenicillin; Ceftazidime; Cystic Fibrosis; Disease Progression; Humans; Injections, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Ticarcillin; Tobramycin	2012
Pharmacokinetics and bioavailability of aerosolized tobramycin in cystic fibrosis. Chest, 2002, Volume: 122, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Biological Availability; Child; Cystic Fibrosis; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Randomized Controlled Trials as Topic; Severity of Illness Index; Tobramycin; United States	2002
TOBI: reducing the impact of pseudomonal infection. Hospital medicine (London, England : 1998), 2002, Volume: 63, Issue:7 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Drug Resistance; Forced Expiratory Volume; Humans; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2002
[Anti-Pseudomonas aerosol therapy in cystic fibrosis: improvement with tobramycin]. Revue de pneumologie clinique, 2002, Volume: 58, Issue:3 Pt 1 Topics: Administration, Inhalation; Adolescent; Aerosols; Anti-Bacterial Agents; Carbenicillin; Child; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Gentamicins; Humans; Nebulizers and Vaporizers; Penicillins; Placebos; Polymyxins; Pseudomonas Infections; Randomized Controlled Trials as Topic; Time Factors; Tobramycin	2002
Inhaled tobramycin (TOBI): a review of its use in the management of Pseudomonas aeruginosa infections in patients with cystic fibrosis. Drugs, 2003, Volume: 63, Issue:22 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Clinical Trials as Topic; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Pseudomonas Infections; Quality of Life; Tobramycin	2003
Bringing new treatments to the bedside in cystic fibrosis. Pediatric pulmonology, 2004, Volume: 37, Issue:2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Clinical Trials as Topic; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxyribonuclease I; Drug Approval; Drug Design; Ethics, Clinical; Genetic Therapy; Humans; Pseudomonas Infections; Tobramycin	2004
Inhaled antibiotic therapy: What drug? What dose? What regimen? What formulation? Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2002, Volume: 1, Issue:Suppl 2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	2002
Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:9 Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Bronchopneumonia; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Humans; Inhalation; Injections, Intravenous; Lung Diseases; Pneumonia, Bacterial; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2005
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1 Topics: Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2006
Inhalation solutions: which one are allowed to be mixed? Physico-chemical compatibility of drug solutions in nebulizers. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2006, Volume: 5, Issue:4 Topics: Acetylcysteine; Administration, Inhalation; Albuterol; Anti-Asthmatic Agents; Anti-Bacterial Agents; Asthma; Bronchodilator Agents; Budesonide; Colistin; Cromolyn Sodium; Cystic Fibrosis; Deoxyribonuclease I; Drug Therapy, Combination; Expectorants; Humans; Ipratropium; Nebulizers and Vaporizers; Respiratory Therapy; Tobramycin	2006
Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis. Current opinion in pulmonary medicine, 2006, Volume: 12, Issue:6 Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Vaccination	2006
Tobramycin solution for inhalation in cystic fibrosis patients: a review of the literature. Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:4 Topics: Administration, Inhalation; Anti-Bacterial Agents; Bacterial Infections; Cystic Fibrosis; Drug Resistance; Humans; Safety; Tobramycin; Treatment Outcome	2007
Costs, quality of life and treatment compliance associated with antibiotic therapies in patients with cystic fibrosis: a review of the literature. Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:5 Topics: Anti-Bacterial Agents; Azithromycin; Cystic Fibrosis; Health Care Costs; Humans; Patient Compliance; Quality of Life; Respiratory Tract Infections; Severity of Illness Index; Tobramycin	2008
Clinical aspects of pseudomonas infections. The West Virginia medical journal, 1981, Volume: 77, Issue:12 Topics: Agammaglobulinemia; Blood Transfusion; Burns; Carbenicillin; Cystic Fibrosis; Drug Therapy, Combination; Endocarditis; Gentamicins; Granulocytes; Humans; Immunosuppression Therapy; Otitis Externa; Pseudomonas aeruginosa; Pseudomonas Infections; Ticarcillin; Tobramycin; Urinary Catheterization; Urologic Diseases	1981
Aerosol delivery of antibiotics to the lower airways of patients with cystic fibrosis. Chest, 1995, Volume: 107, Issue:2 Suppl Topics: Administration, Inhalation; Aerosols; Bronchial Diseases; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	1995
Inhalation-based therapies in the treatment of cystic fibrosis. Current opinion in pediatrics, 1994, Volume: 6, Issue:3 Topics: Administration, Inhalation; Aerosols; Amiloride; Cystic Fibrosis; Deoxyribonucleases; Drug Carriers; Humans; Liposomes; Phosphatidylglycerols; Protease Inhibitors; Respiratory Therapy; Tobramycin; Uridine Triphosphate	1994
Once-daily dosing regimen for aminoglycoside plus betalactam combination therapy of serious lower respiratory tract infections. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7, Issue:4 Topics: Administration, Oral; Anti-Bacterial Agents; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lactams; Respiratory Tract Infections; Tobramycin	1995
[Inhalational antibiotic therapy in patients with cystic fibrosis and Pseudomonas infection]. Schweizerische medizinische Wochenschrift, 1997, May-24, Volume: 127, Issue:21 Topics: Administration, Inhalation; Anti-Bacterial Agents; Bronchitis; Colistin; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas Infections; Tobramycin	1997
Use of aerosolized antibiotics in patients with cystic fibrosis. Chest, 1999, Volume: 116, Issue:3 Topics: Aerosols; Anti-Bacterial Agents; Bacterial Infections; Cystic Fibrosis; Drug Monitoring; Drug Resistance, Microbial; Humans; Patient Selection; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	1999
Inhaled antimicrobial therapy. Respiratory care clinics of North America, 1999, Volume: 5, Issue:4 Topics: Administration, Inhalation; Aerosols; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bronchitis; Colony Count, Microbial; Cystic Fibrosis; Humans; Lung Diseases; Pentamidine; Pneumonia, Pneumocystis; Respiration, Artificial; Ribavirin; Sputum; Tobramycin; Tracheitis	1999
New approaches to optimizing antimicrobial therapy in patients with cystic fibrosis. Current opinion in pulmonary medicine, 1999, Volume: 5, Issue:6 Topics: Acute Disease; Administration, Inhalation; Aerosols; Airway Obstruction; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chronic Disease; Cystic Fibrosis; Humans; Lung Diseases; Macrolides; Membrane Proteins; Nutritional Physiological Phenomena; Peptides; Tobramycin	1999
Technical report: precautions regarding the use of aerosolized antibiotics. Committee on Infectious Diseases and Committee on Drugs. Pediatrics, 2000, Volume: 106, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Bronchoconstriction; Child; Cystic Fibrosis; Drug Administration Schedule; Drug Resistance, Microbial; Environmental Pollution; Gentamicins; Humans; Length of Stay; Licensure; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; United States	2000
Sinonasal disease in cystic fibrosis: clinical characteristics, diagnosis, and management. Pediatric pulmonology, 2000, Volume: 30, Issue:6 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Endoscopy; Humans; Infant; Nasal Mucosa; Nasal Polyps; Paranasal Sinus Diseases; Pseudomonas Infections; Quality of Life; Recurrence; Tobramycin	2000
Cystic fibrosis. Thorax, 2001, Volume: 56, Issue:3 Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacterial Infections; Child; Child, Preschool; Cystic Fibrosis; Genetic Therapy; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Neonatal Screening; Physical Therapy Modalities; Tobramycin	2001
Recent advances in cystic fibrosis. Archives of disease in childhood, 2001, Volume: 85, Issue:1 Topics: Adolescent; Adult; Animals; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Delivery of Health Care; Genetic Testing; Genetic Therapy; Genotype; Humans; Infant; Infant, Newborn; Life Expectancy; Lung Transplantation; Macrolides; Mice; Opportunistic Infections; Phenotype; Prognosis; Tobramycin	2001
Efficacy and safety of aerosolized tobramycin in cystic fibrosis. Pediatric pulmonology, 2001, Volume: 32, Issue:4 Topics: Administration, Inhalation; Adolescent; Aerosols; Biological Availability; Child; Child, Preschool; Consumer Product Safety; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Nebulizers and Vaporizers; Sensitivity and Specificity; Tobramycin; Treatment Outcome	2001
The rationale for aerosolized antibiotics. Pharmacotherapy, 2002, Volume: 22, Issue:3 Pt 2 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Dosage Forms; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistance, Bacterial; Humans; Risk Factors; Tobramycin	2002
Respiratory infections: clinical evaluation. Clinical therapeutics, 1985, Volume: 7 Suppl A Topics: Amikacin; Carbenicillin; Cefotaxime; Cystic Fibrosis; Drug Therapy, Combination; Enterobacteriaceae; Haemophilus influenzae; Humans; Piperacillin; Pseudomonas Infections; Respiratory Tract Infections; Streptococcus; Streptococcus pneumoniae; Tobramycin	1985

Trials

150 trial(s) available for tobramycin and Cystic Fibrosis

Article	Year
Testing the effects of combining azithromycin with inhaled tobramycin for Thorax, 2022, Volume: 77, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Azithromycin; Cystic Fibrosis; Forced Expiratory Volume; Humans; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2022
Amikacin liposome inhalation suspension for chronic Pseudomonas aeruginosa infection in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2020, Volume: 19, Issue:2 Topics: Administration, Inhalation; Adult; Amikacin; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Hospitalization; Humans; Liposomes; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Sputum; Surveys and Questionnaires; Symptom Assessment; Symptom Flare Up; Tobramycin; Treatment Outcome	2020
A randomised controlled trial of rosuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis. Scientific reports, 2020, 02-04, Volume: 10, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Hepatitis A Virus Cellular Receptor 1; Humans; Kidney Diseases; Male; Rosuvastatin Calcium; Tobramycin	2020
Does Circadian Rhythm Affect the Pharmacokinetics of Once-Daily Tobramycin in Adults With Cystic Fibrosis? Therapeutic drug monitoring, 2020, Volume: 42, Issue:4 Topics: Administration, Intravenous; Adult; Aminoglycosides; Circadian Rhythm; Cystic Fibrosis; Drug Administration Schedule; Female; Humans; Male; Tobramycin	2020
An 8 week open-label interventional multicenter study to explore the lung clearance index as endpoint for clinical trials in cystic fibrosis patients ≥8 years of age, chronically infected with Pseudomonas aeruginosa. BMC pulmonary medicine, 2020, Jun-12, Volume: 20, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Pilot Projects; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Young Adult	2020
Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial. The Lancet. Respiratory medicine, 2020, Volume: 8, Issue:10 Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Ceftazidime; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome; Young Adult	2020
Ease of use of tobramycin inhalation powder compared with nebulized tobramycin and colistimethate sodium: a crossover study in cystic fibrosis patients with pulmonary Pseudomonas aeruginosa infection. Therapeutic advances in respiratory disease, 2017, Volume: 11, Issue:7 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Colistin; Cross-Over Studies; Cystic Fibrosis; Equipment Contamination; Equipment Design; Europe; Female; Forced Expiratory Volume; Humans; Lung; Male; Nebulizers and Vaporizers; Patient Satisfaction; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome; Young Adult	2017
Population Pharmacokinetics of Tobramycin Inhalation Solution in Pediatric Patients With Cystic Fibrosis. Journal of pharmaceutical sciences, 2017, Volume: 106, Issue:11 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Biological Availability; Child; Child, Preschool; Computer Simulation; Cystic Fibrosis; Female; Humans; Infant; Male; Models, Biological; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome; Young Adult	2017
Eradication of early P. aeruginosa infection in children <7 years of age with cystic fibrosis: The early study. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2019, Volume: 18, Issue:1 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Child, Preschool; Cross-Over Studies; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Retrospective Studies; Sputum; Time Factors; Tobramycin; Treatment Outcome	2019
Azithromycin for Early Pseudomonas Infection in Cystic Fibrosis. The OPTIMIZE Randomized Trial. American journal of respiratory and critical care medicine, 2018, 11-01, Volume: 198, Issue:9 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Azithromycin; Child; Child, Preschool; Cystic Fibrosis; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infant; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Time Factors; Tobramycin; Treatment Outcome	2018
Pharmacokinetics and safety of tobramycin nebulization with the I-neb and PARI-LC Plus in children with cystic fibrosis: A randomized, crossover study. British journal of clinical pharmacology, 2019, Volume: 85, Issue:9 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Audiometry; Child; Cross-Over Studies; Cystic Fibrosis; Drug Monitoring; Equipment Design; Female; Glomerular Filtration Rate; Hearing; Humans; Kidney; Male; Nebulizers and Vaporizers; Patient Satisfaction; Solutions; Tobramycin	2019
Tobramycin inhalation powder manufactured by improved process in cystic fibrosis: the randomized EDIT trial. Current medical research and opinion, 2013, Volume: 29, Issue:8 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Placebos; Powders; Spirometry; Tobramycin	2013
A pharmacokinetics and safety comparison of a highly concentrated tobramycin solution with TOBI. Journal of aerosol medicine and pulmonary drug delivery, 2014, Volume: 27, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Area Under Curve; Chemistry, Pharmaceutical; Child; Cystic Fibrosis; Drug Monitoring; Equipment Design; Forced Expiratory Volume; Germany; Humans; Lung; Male; Nebulizers and Vaporizers; Sputum; Tobramycin; Treatment Outcome; Young Adult	2014
Inhaled tobramycin effectively reduces FEV1 decline in cystic fibrosis. An instrumental variables analysis. Annals of the American Thoracic Society, 2013, Volume: 10, Issue:3 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Follow-Up Studies; Humans; Male; Maximal Expiratory Flow Rate; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin; Treatment Outcome; Young Adult	2013
Standard care versus protocol based therapy for new onset Pseudomonas aeruginosa in cystic fibrosis. Pediatric pulmonology, 2013, Volume: 48, Issue:10 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Female; Hospitalization; Humans; Infant; Male; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Tobramycin; Treatment Outcome	2013
Pharmacokinetics and pharmacodynamics of once-daily administration of intravenous tobramycin in adult patients with cystic fibrosis hospitalized for an acute pulmonary exacerbation. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:10 Topics: Administration, Intravenous; Adult; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Pseudomonas Infections; Tobramycin; Young Adult	2013
Tobramycin inhalation powder in cystic fibrosis patients: response by age group. Respiratory care, 2014, Volume: 59, Issue:3 Topics: Administration, Inhalation; Adolescent; Age Factors; Anti-Bacterial Agents; Child; Confidence Intervals; Cystic Fibrosis; Dry Powder Inhalers; Female; Forced Expiratory Volume; Humans; Male; Patient Satisfaction; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Young Adult	2014
Nebulized tobramycin in the treatment of adult CF pulmonary exacerbations. Journal of aerosol medicine and pulmonary drug delivery, 2014, Volume: 27, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Disease Progression; England; Female; Humans; Injections, Intravenous; Kidney; Lung; Male; Nebulizers and Vaporizers; Pilot Projects; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Time Factors; Tobramycin; Treatment Outcome; Young Adult	2014
Long-term efficacy and safety of aerosolized tobramycin 300 mg/4 ml in cystic fibrosis. Pediatric pulmonology, 2014, Volume: 49, Issue:11 Topics: Administration, Inhalation; Adolescent; Aerosols; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin; Treatment Outcome	2014
Azithromycin may antagonize inhaled tobramycin when targeting Pseudomonas aeruginosa in cystic fibrosis. Annals of the American Thoracic Society, 2014, Volume: 11, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Aztreonam; Cystic Fibrosis; Drug Interactions; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; Young Adult	2014
Sinonasal inhalation of tobramycin vibrating aerosol in cystic fibrosis patients with upper airway Pseudomonas aeruginosa colonization: results of a randomized, double-blind, placebo-controlled pilot study. Drug design, development and therapy, 2014, Volume: 8 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Nasal Mucosa; Pilot Projects; Pseudomonas aeruginosa; Tobramycin	2014
Efficacy and tolerability of a new nasal spray formulation containing hyaluronate and tobramycin in cystic fibrosis patients with bacterial rhinosinusitis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Child; Child, Preschool; Cystic Fibrosis; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Hyaluronic Acid; Male; Nasal Mucosa; Nasal Sprays; Pilot Projects; Rhinitis; Sinusitis; Tobramycin; Treatment Outcome; Young Adult	2014
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet. Respiratory medicine, 2014, Volume: 2, Issue:7 Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Bacterial Agents; Child; Chlorides; Codon, Nonsense; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Progression; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Oxadiazoles; Sweat; Tobramycin; Young Adult	2014
Comparison of two tobramycin nebuliser solutions: pharmacokinetic, efficacy and safety profiles of T100 and TNS. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Child; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Male; Nebulizers and Vaporizers; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Therapeutic Equivalency; Tobramycin; Treatment Outcome; Young Adult	2014
A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2015, Volume: 14, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Levofloxacin; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; Treatment Outcome; Young Adult	2015
The influence of breathing mode on tobramycin serum levels using the I-neb AAD system in adults with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2015, Volume: 14, Issue:6 Topics: Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Respiration; Tobramycin; Young Adult	2015
Inhaled aztreonam lysine versus inhaled tobramycin in cystic fibrosis. An economic evaluation. Annals of the American Thoracic Society, 2015, Volume: 12, Issue:7 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cost-Benefit Analysis; Cystic Fibrosis; Female; Humans; Lung Transplantation; Male; Models, Economic; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; United States; Young Adult	2015
The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:4 Topics: Adolescent; Aminoglycosides; Anti-Bacterial Agents; Child; Circadian Rhythm; Cystic Fibrosis; Drug Administration Schedule; Drug Chronotherapy; Drug Monitoring; Female; Hepatitis A Virus Cellular Receptor 1; Humans; Kidney; Male; Melatonin; Renal Elimination; Tobramycin; Treatment Outcome; Urinalysis	2016
Pharmacokinetics and safety of an 8 week continuous treatment with once-daily versus twice-daily inhalation of tobramycin in cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Male; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Serum; Tobramycin; Young Adult	2016
One-year safety and efficacy of tobramycin powder for inhalation in patients with cystic fibrosis. Pediatric pulmonology, 2016, Volume: 51, Issue:4 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Microbial Sensitivity Tests; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin; Treatment Outcome; Young Adult	2016
Pharmacokinetics and Tolerability of Once Daily Double Dose Tobramycin Inhalation in Cystic Fibrosis Using Controlled and Conventional Nebulization. Journal of aerosol medicine and pulmonary drug delivery, 2016, Volume: 29, Issue:3 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Drug Administration Schedule; Drug Monitoring; Female; Humans; Lung; Male; Middle Aged; Nebulizers and Vaporizers; Netherlands; Patient Satisfaction; Tobramycin; Treatment Outcome; Young Adult	2016
Safety and efficacy of prolonged levofloxacin inhalation solution (APT-1026) treatment for cystic fibrosis and chronic Pseudomonas aeruginosa airway infection. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:5 Topics: Administration, Inhalation; Adult; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Levofloxacin; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2016
Continuous alternating inhaled antibiotics for chronic pseudomonal infection in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Medication Therapy Management; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome	2016
Long-term safety of tobramycin inhalation powder in patients with cystic fibrosis: phase IV (ETOILES) study. Current medical research and opinion, 2016, Volume: 32, Issue:11 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Cough; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2016
Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:3 Topics: Anti-Bacterial Agents; Azithromycin; Aztreonam; Cystic Fibrosis; Drug Administration Routes; Drug Interactions; Drug Monitoring; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome; Young Adult	2017
Pilot trial of tobramycin inhalation powder in cystic fibrosis patients with chronic Burkholderia cepacia complex infection. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Canada; Child; Cystic Fibrosis; Drug Monitoring; Female; Forced Expiratory Volume; Humans; Male; Pilot Projects; Respiratory Tract Infections; Sputum; Tobramycin; Treatment Outcome	2017
Rapid pulmonary delivery of inhaled tobramycin for Pseudomonas infection in cystic fibrosis: a pilot project. Pediatric pulmonology, 2008, Volume: 43, Issue:8 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Pilot Projects; Pseudomonas Infections; Time Factors; Tobramycin; Treatment Outcome	2008
Aerosolization of tobramycin (TOBI) with the PARI LC PLUS reusable nebulizer: which compressor to use? Comparison of the CR60 to the PortaNeb compressor. Journal of aerosol medicine and pulmonary drug delivery, 2008, Volume: 21, Issue:3 Topics: Administration, Inhalation; Adult; Aerosols; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Cystic Fibrosis; Equipment Design; Female; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Patient Satisfaction; Pilot Projects; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Solutions; Tissue Distribution; Tobramycin; Young Adult	2008
Early anti-pseudomonal acquisition in young patients with cystic fibrosis: rationale and design of the EPIC clinical trial and observational study'. Contemporary clinical trials, 2009, Volume: 30, Issue:3 Topics: Age Factors; Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxacin; Cohort Studies; Cystic Fibrosis; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Longitudinal Studies; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Tobramycin; Treatment Outcome	2009
Pharmacokinetics and safety of tobramycin administered by the PARI eFlow rapid nebulizer in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2009, Volume: 8, Issue:5 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Lung; Lung Diseases; Male; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome; Young Adult	2009
Tobramycin once- vs thrice-daily for elective intravenous antipseudomonal therapy in pediatric cystic fibrosis patients. Infection, 2009, Volume: 37, Issue:5 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Infant; Infusions, Intravenous; Male; Pneumonia, Bacterial; Pseudomonas Infections; Tobramycin; Treatment Outcome	2009
Continuous vs thrice-daily ceftazidime for elective intravenous antipseudomonal therapy in cystic fibrosis. Infection, 2009, Volume: 37, Issue:5 Topics: Adolescent; Adult; Anti-Bacterial Agents; Ceftazidime; Child; Child, Preschool; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Pneumonia, Bacterial; Pseudomonas Infections; Tobramycin; Treatment Outcome; Young Adult	2009
Can Burkholderia cepacia complex be eradicated with nebulised amiloride and TOBI? Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2010, Volume: 9, Issue:1 Topics: Adolescent; Amiloride; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Child; Cystic Fibrosis; Drug Therapy, Combination; Humans; Nebulizers and Vaporizers; Sodium Channel Blockers; Tobramycin	2010
Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis: the ELITE trial. Thorax, 2010, Volume: 65, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Female; Humans; Infant; Male; Opportunistic Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome; Young Adult	2010
The use of high resolution computerized tomography (HRCT) of the chest in evaluating the effect of tobramycin solution for inhalation in cystic fibrosis lung disease. Pediatric pulmonology, 2010, Volume: 45, Issue:5 Topics: Administration, Inhalation; Anti-Bacterial Agents; Bronchiectasis; Child; Cystic Fibrosis; Female; Humans; Lung; Male; Pilot Projects; Pseudomonas aeruginosa; Pseudomonas Infections; Spirometry; Sputum; Tobramycin; Tomography, X-Ray Computed	2010
Lung deposition of inhaled tobramycin with eFlow rapid/LC Plus jet nebuliser in healthy and cystic fibrosis subjects. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Bacterial Agents; Biological Availability; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Monitoring; Female; Humans; Lung; Male; Middle Aged; Nebulizers and Vaporizers; Organ Specificity; Radionuclide Imaging; Respiratory Function Tests; Tobramycin	2011
Twice vs three-times daily antibiotics in the treatment of pulmonary exacerbations of cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:1 Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Cystic Fibrosis; Disease Progression; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Ear Diseases; Female; Humans; Injections, Intravenous; Kidney Diseases; Lung; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome	2011
Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa. The Journal of infectious diseases, 2010, Nov-15, Volume: 202, Issue:10 Topics: Administration, Inhalation; Adult; Animals; Anti-Bacterial Agents; Biofilms; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Lung; Male; Microbial Sensitivity Tests; Pilot Projects; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Inbred Lew; Tobramycin; Treatment Outcome	2010
Tobramycin inhalation powder for P. aeruginosa infection in cystic fibrosis: the EVOLVE trial. Pediatric pulmonology, 2011, Volume: 46, Issue:3 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Young Adult	2011
Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Cough; Cystic Fibrosis; Drug Administration Schedule; Drug Delivery Systems; Drug Monitoring; Dry Powder Inhalers; Female; Humans; Male; Middle Aged; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Sputum; Tobramycin; Treatment Outcome	2011
Higher tobramycin concentration and vibrating mesh technology can shorten antibiotic treatment time in cystic fibrosis. Pediatric pulmonology, 2011, Volume: 46, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Lung; Male; Nebulizers and Vaporizers; Patient Preference; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome; Young Adult	2011
Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis. Pediatric pulmonology, 2012, Volume: 47, Issue:2 Topics: Anti-Bacterial Agents; Child; Child, Preschool; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Risk; Tobramycin; Treatment Failure	2012
Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis. Archives of pediatrics & adolescent medicine, 2011, Volume: 165, Issue:9 Topics: Administration, Inhalation; Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Infant; Male; Placebos; Proportional Hazards Models; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome; United States	2011
Fosfomycin/tobramycin for inhalation in patients with cystic fibrosis with pseudomonas airway infection. American journal of respiratory and critical care medicine, 2012, Jan-15, Volume: 185, Issue:2 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Cough; Cystic Fibrosis; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Fosfomycin; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome; United States	2012
Early antibiotic treatment for Pseudomonas aeruginosa eradication in patients with cystic fibrosis: a randomised multicentre study comparing two different protocols. Thorax, 2012, Volume: 67, Issue:10 Topics: Administration, Inhalation; Administration, Oral; Anti-Bacterial Agents; Chi-Square Distribution; Child; Child, Preschool; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Infant; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Stenotrophomonas maltophilia; Tobramycin; Treatment Outcome	2012
Validation of the Treatment Satisfaction Questionnaire for Medication in patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012, Volume: 11, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Humans; Male; Medication Adherence; Nebulizers and Vaporizers; Patient Satisfaction; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Psychometrics; Reproducibility of Results; Surveys and Questionnaires; Tobramycin; Young Adult	2012
Sputum tobramycin concentrations in cystic fibrosis patients with repeated administration of inhaled tobramycin. Journal of aerosol medicine and pulmonary drug delivery, 2013, Volume: 26, Issue:2 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Chromatography, High Pressure Liquid; Cystic Fibrosis; Drug Administration Schedule; Feasibility Studies; Humans; Male; Pilot Projects; Sputum; Time Factors; Tobramycin; Young Adult	2013
Monitoring of tobramycin levels in patients with cystic fibrosis by finger-prick sampling. The European respiratory journal, 2012, Volume: 39, Issue:6 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Drug Monitoring; Humans; Pneumonia, Bacterial; Tobramycin	2012
Comparison of two treatment regimens for eradication of Pseudomonas aeruginosa infection in children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:1 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Infant; Male; Prospective Studies; Pseudomonas Infections; Sputum; Tobramycin; Treatment Outcome	2013
Inhaled aztreonam lysine vs. inhaled tobramycin in cystic fibrosis: a comparative efficacy trial. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:2 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Child; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome	2013
Safety, efficacy and convenience of colistimethate sodium dry powder for inhalation (Colobreathe DPI) in patients with cystic fibrosis: a randomised study. Thorax, 2013, Volume: 68, Issue:4 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Clinical Trials, Phase III as Topic; Colistin; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Powders; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome; Young Adult	2013
Pharmacokinetic and tolerability profiles of tobramycin nebuliser solution 300 mg/4 ml administered by PARI eFlow(®) rapid and PARI LC Plus(®) nebulisers in cystic fibrosis patients. Pulmonary pharmacology & therapeutics, 2013, Volume: 26, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Pseudomonas Infections; Sputum; Tobramycin	2013
Comparison of central venous catheter and peripheral vein samples of antibiotics in children with cystic fibrosis. Journal for specialists in pediatric nursing : JSPN, 2013, Volume: 18, Issue:1 Topics: Adolescent; Catheterization, Central Venous; Catheterization, Peripheral; Child; Child, Preschool; Cohort Studies; Cystic Fibrosis; Drug Monitoring; Female; Hospitals, Pediatric; Humans; Male; Sensitivity and Specificity; Specimen Handling; Tobramycin; Vancomycin	2013
[Nebulized colistin versus tobramycin in the treatment of chronic Pseudomonas colonization in cystic fibrosis patients]. Medicina clinica, 2014, Jan-21, Volume: 142, Issue:2 Topics: Administration, Inhalation; Body Mass Index; Child; Child, Preschool; Colistin; Cross-Over Studies; Cystic Fibrosis; Drug Resistance, Bacterial; Female; Forced Expiratory Volume; Humans; Lung; Male; Nebulizers and Vaporizers; Patient Satisfaction; Pseudomonas aeruginosa; Sputum; Surveys and Questionnaires; Tobramycin; Treatment Outcome	2014
Bronchial reactions to the inhalation of high-dose tobramycin in cystic fibrosis. The European respiratory journal, 2002, Volume: 20, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bronchi; Bronchial Spasm; Child; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Humans; Male; Phenol; Preservatives, Pharmaceutical; Respiratory Function Tests; Tobramycin	2002
Evaluation of bronchial constriction in children with cystic fibrosis after inhaling two different preparations of tobramycin. Chest, 2002, Volume: 122, Issue:3 Topics: Administration, Inhalation; Adolescent; Bronchial Hyperreactivity; Bronchoconstriction; Child; Cross-Over Studies; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Pneumonia, Bacterial; Preservatives, Pharmaceutical; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Spirometry; Tobramycin	2002
A randomised clinical trial of nebulised tobramycin or colistin in cystic fibrosis. The European respiratory journal, 2002, Volume: 20, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Chronic Disease; Colistin; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2002
Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis. American journal of respiratory and critical care medicine, 2003, Mar-15, Volume: 167, Issue:6 Topics: Administration, Inhalation; Age Factors; Anti-Bacterial Agents; Audiometry; Bronchoalveolar Lavage Fluid; Carrier State; Child, Preschool; Creatinine; Cystic Fibrosis; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Female; Genotype; Hearing Disorders; Humans; Kidney Diseases; Male; Oropharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Safety; Severity of Illness Index; Sputum; Tobramycin; Treatment Outcome	2003
Efficiency of pulmonary administration of tobramycin solution for inhalation in cystic fibrosis using an improved drug delivery system. Chest, 2003, Volume: 123, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cross-Over Studies; Cystic Fibrosis; Drug Delivery Systems; Equipment Design; Female; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Solutions; Tobramycin	2003
An in vivo assessment of the tobramycin/ticarcillin interaction in cystic fibrosis patients. British journal of clinical pharmacology, 1993, Volume: 36, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Drug Combinations; Drug Interactions; Humans; Infusions, Intravenous; Penicillins; Ticarcillin; Tobramycin	1993
Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease. Pediatric pulmonology, 2004, Volume: 38, Issue:4 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Cough; Cystic Fibrosis; Female; Fever; Hospitalization; Humans; Lung Diseases; Male; Survival Analysis; Survival Rate; Time Factors; Tobramycin; Treatment Outcome	2004
The long-term use of inhaled tobramycin in patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2002, Volume: 1, Issue:Suppl 2 Topics: Administration, Inhalation; Adolescent; Adult; Age Factors; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Humans; Lung Diseases; Male; Pseudomonas Infections; Time Factors; Tobramycin; Treatment Outcome	2002
Heterogeneity of treatment response to azithromycin in patients with cystic fibrosis. American journal of respiratory and critical care medicine, 2005, Oct-15, Volume: 172, Issue:8 Topics: Anti-Bacterial Agents; Azithromycin; Cystic Fibrosis; Deoxyribonuclease I; Drug Monitoring; Forced Expiratory Volume; Genotype; Heterozygote; Homozygote; Hospitalization; Humans; Pneumonia, Bacterial; Predictive Value of Tests; Proportional Hazards Models; Pseudomonas Infections; Risk Factors; Severity of Illness Index; Tobramycin; Treatment Outcome; United States	2005
The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosis. Chest, 2005, Volume: 128, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Child; Child, Preschool; Cystic Fibrosis; Disease Progression; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Meropenem; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Sputum; Thienamycins; Tobramycin	2005
Absence of cochleotoxicity measured by standard and high-frequency pure tone audiometry in a trial of once- versus three-times-daily tobramycin in cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:7 Topics: Adolescent; Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Hearing Loss; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2006
Open follow-up study of tobramycin nebuliser solution and colistin in patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2006, Volume: 5, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Chronic Disease; Colistin; Cross-Over Studies; Cystic Fibrosis; Female; Follow-Up Studies; Humans; Male; Pseudomonas Infections; Tobramycin	2006
Nebulisers comparison with inhaled tobramycin in young children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2007, Volume: 6, Issue:2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Child, Preschool; Cross-Over Studies; Cystic Fibrosis; Drug Delivery Systems; Female; Humans; Infant; Male; Nebulizers and Vaporizers; Pilot Projects; Tobramycin	2007
Once-daily tobramycin in cystic fibrosis: better for clinical outcome than thrice-daily tobramycin but more resistance development? The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:4 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Drug Resistance, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome	2006
High resolution computerized tomography of the chest and pulmonary function testing in evaluating the effect of tobramycin solution for inhalation in cystic fibrosis patients. Pediatric pulmonology, 2006, Volume: 41, Issue:12 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Follow-Up Studies; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Male; Pilot Projects; Radiography, Thoracic; Retrospective Studies; Tobramycin; Tomography, X-Ray Computed; Treatment Outcome	2006
Population pharmacokinetics of tobramycin administered thrice daily and once daily in children and adults with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2007, Volume: 6, Issue:5 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Male; Models, Theoretical; Retrospective Studies; Tobramycin	2007
Novel tobramycin inhalation powder in cystic fibrosis subjects: pharmacokinetics and safety. Pediatric pulmonology, 2007, Volume: 42, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cough; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Dysgeusia; Female; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Opportunistic Infections; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	2007
Long-term benefits of inhaled tobramycin in children with cystic fibrosis: first clinical observations from Poland. Respiration; international review of thoracic diseases, 2008, Volume: 75, Issue:2 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Humans; Male; Poland; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	2008
Clinical pharmacology study of Bramitob, a tobramycin solution for nebulization, in comparison with Tobi. Paediatric drugs, 2007, Volume: 9 Suppl 1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Biological Availability; Chronic Disease; Cross-Over Studies; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Nebulizers and Vaporizers; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Therapeutic Equivalency; Tobramycin	2007
Efficacy, safety, and local pharmacokinetics of highly concentrated nebulized tobramycin in patients with cystic fibrosis colonized with Pseudomonas aeruginosa. Paediatric drugs, 2007, Volume: 9 Suppl 1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Nebulizers and Vaporizers; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2007
A formulation of aerosolized tobramycin (Bramitob) in the treatment of patients with cystic fibrosis and Pseudomonas aeruginosa infection: a double-blind, placebo-controlled, multicenter study. Paediatric drugs, 2007, Volume: 9 Suppl 1 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2007
Efficacy and safety of intravenous meropenem and tobramycin versus ceftazidime and tobramycin in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2008, Volume: 7, Issue:2 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; C-Reactive Protein; Ceftazidime; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Male; Meropenem; Prospective Studies; Thienamycins; Tobramycin; Treatment Outcome	2008
Estimating in vivo airway surface liquid concentration in trials of inhaled antibiotics. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine, 2007,Fall, Volume: 20, Issue:3 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Computer Simulation; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Models, Biological; Nebulizers and Vaporizers; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Research Design; Respiratory Mechanics; Respiratory System; Sputum; Taurine; Thiadiazines; Tobramycin	2007
Sputum antibiotic concentrations: implications for treatment of cystic fibrosis lung infection. Pediatric pulmonology, 2007, Volume: 42, Issue:11 Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Infusions, Intravenous; Microbial Sensitivity Tests; Middle Aged; Pseudomonas Infections; Sputum; Tobramycin	2007
Inhalation of tobramycin in patients with cystic fibrosis: comparison of two methods. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58 Suppl 5, Issue:Pt 1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Drug Administration Schedule; Equipment Design; Feasibility Studies; Forced Expiratory Volume; Humans; Nebulizers and Vaporizers; Respiratory Mechanics; Tobramycin; Treatment Outcome	2007
Clinical and bacteriological responses to three antibiotic regimens for acute exacerbations of cystic fibrosis: ticarcillin-tobramycin, azlocillin-tobramycin, and azlocillin-placebo. The Journal of infectious diseases, 1983, Volume: 147, Issue:3 Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Azlocillin; Child; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Drug Therapy, Combination; Humans; Lung; Penicillin Resistance; Penicillins; Random Allocation; Ticarcillin; Tobramycin	1983
Randomized, double-blind evaluation of azlocillin for the treatment of pulmonary exacerbations of cystic fibrosis. The Journal of antimicrobial chemotherapy, 1983, Volume: 11 Suppl B Topics: Adolescent; Adult; Aged; Azlocillin; Bacterial Infections; Child; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Drug Therapy, Combination; Humans; Lung Diseases; Middle Aged; Penicillins; Random Allocation; Respiratory Function Tests; Sputum; Ticarcillin; Tobramycin	1983
Ceftazidime treatment of chronic Pseudomonas aeruginosa respiratory tract infection in cystic fibrosis. The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A Topics: Adolescent; Adult; Carbenicillin; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Penicillin Resistance; Prospective Studies; Pseudomonas Infections; Random Allocation; Respiratory Function Tests; Respiratory Tract Infections; Tobramycin	1983
Disposition of tobramycin in patients with cystic fibrosis: a prospective controlled study. The Journal of pediatrics, 1984, Volume: 105, Issue:1 Topics: Adolescent; Adult; Body Surface Area; Child; Clinical Trials as Topic; Cystic Fibrosis; Female; Gentamicins; Glomerular Filtration Rate; Humans; Kinetics; Male; Prospective Studies; Protein Binding; Pseudomonas Infections; Tobramycin	1984
Piperacillin and tobramycin in the treatment of Pseudomonas lung infections in cystic fibrosis. The Journal of antimicrobial chemotherapy, 1983, Volume: 12, Issue:2 Topics: Adolescent; Child; Cystic Fibrosis; Drug Therapy, Combination; Humans; Lung Diseases; Piperacillin; Pseudomonas Infections; Tobramycin	1983
Comparative study of the antibacterial activity of amikacin and tobramycin during Pseudomonas pulmonary infection in patients with cystic fibrosis. The Journal of antimicrobial chemotherapy, 1982, Volume: 10, Issue:3 Topics: Amikacin; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Kanamycin; Kinetics; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1982
Once-daily vs. continuous aminoglycoside dosing: efficacy and toxicity in animal and clinical studies of gentamicin, netilmicin, and tobramycin. The Journal of infectious diseases, 1983, Volume: 147, Issue:5 Topics: Adult; Animals; Anti-Bacterial Agents; Cystic Fibrosis; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Endocarditis, Bacterial; Female; Gentamicins; Glomerular Filtration Rate; Guinea Pigs; Humans; Male; Netilmicin; Pneumonia; Pseudomonas Infections; Rabbits; Rats; Rats, Inbred Strains; Tobramycin	1983
Acute pulmonary exacerbations in cystic fibrosis. A double-blind trial of tobramycin and placebo therapy. American journal of diseases of children (1960), 1980, Volume: 134, Issue:12 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Placebos; Pseudomonas; Sputum; Staphylococcus aureus; Tobramycin	1980
Efficacy of aerosolized tobramycin in patients with cystic fibrosis. The New England journal of medicine, 1993, Jun-17, Volume: 328, Issue:24 Topics: Adolescent; Aerosols; Bronchitis; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Monitoring, Physiologic; Pseudomonas Infections; Respiratory Mechanics; Tobramycin	1993
Minimisation of aminoglycoside toxicity in patients with cystic fibrosis. Thorax, 1996, Volume: 51, Issue:4 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Drug Administration Schedule; Female; Hearing; Humans; Kidney; Male; Prospective Studies; Time Factors; Tobramycin	1996
Pharmacokinetics of once-daily versus thrice daily tobramycin in cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:5 Topics: Cross-Over Studies; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Pilot Projects; Time Factors; Tobramycin	1996
Pharmacokinetics of aerosolized tobramycin in adult patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Biological Availability; Cystic Fibrosis; Female; Humans; Male; Tobramycin	1997
Sequential ciprofloxacin therapy in pediatric cystic fibrosis: comparative study vs. ceftazidime/tobramycin in the treatment of acute pulmonary exacerbations. The Cystic Fibrosis Study Group. The Pediatric infectious disease journal, 1997, Volume: 16, Issue:1 Topics: Acute Disease; Adolescent; Anti-Infective Agents; Arthralgia; Ceftazidime; Child; Child, Preschool; Ciprofloxacin; Cystic Fibrosis; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Pneumonia, Bacterial; Prospective Studies; Pseudomonas Infections; Tobramycin; Treatment Outcome	1997
A comparison of peak sputum tobramycin concentration in patients with cystic fibrosis using jet and ultrasonic nebulizer systems. Aerosolized Tobramycin Study Group. Chest, 1997, Volume: 111, Issue:4 Topics: Adolescent; Adult; Child; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Male; Nebulizers and Vaporizers; Sputum; Tobramycin; Ultrasonics	1997
Home intravenous therapy in cystic fibrosis: a prospective randomized trial examining clinical, quality of life and cost aspects. The European respiratory journal, 1997, Volume: 10, Issue:4 Topics: Adolescent; Adult; Analysis of Variance; Anti-Bacterial Agents; Ceftazidime; Cost-Benefit Analysis; Cystic Fibrosis; Female; Home Infusion Therapy; Hospitalization; Humans; Male; Prospective Studies; Quality of Life; Tobramycin; Treatment Outcome	1997
Oral ciprofloxacin vs. intravenous ceftazidime plus tobramycin in pediatric cystic fibrosis patients: comparison of antipseudomonas efficacy and assessment of safety with ultrasonography and magnetic resonance imaging. Cystic Fibrosis Study Group. The Pediatric infectious disease journal, 1997, Volume: 16, Issue:6 Topics: Administration, Oral; Adolescent; Cartilage; Ceftazidime; Child; Child, Preschool; Ciprofloxacin; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Magnetic Resonance Imaging; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Ultrasonography	1997
Nutritional impact of antipseudomonas intravenous antibiotic courses in cystic fibrosis. Archives of disease in childhood, 1997, Volume: 76, Issue:5 Topics: Adolescent; Adult; Amikacin; Anthropometry; Body Composition; Ceftazidime; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Nutritional Status; Opportunistic Infections; Prospective Studies; Pseudomonas Infections; Tobramycin	1997
Placebo-controlled, double-blind, randomized study of aerosolized tobramycin for early treatment of Pseudomonas aeruginosa colonization in cystic fibrosis. Pediatric pulmonology, 1998, Volume: 25, Issue:2 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Pharynx; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Tobramycin	1998
The pharmacokinetics and toxicity of once-daily tobramycin therapy in children with cystic fibrosis. The Journal of antimicrobial chemotherapy, 1998, Volume: 42, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Half-Life; Humans; Kidney; Male; Metabolic Clearance Rate; Tobramycin	1998
Efficacy, tolerance, and pharmacokinetics of once daily tobramycin for pseudomonas exacerbations in cystic fibrosis. Archives of disease in childhood, 1998, Volume: 78, Issue:6 Topics: Adolescent; Adult; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Pseudomonas Infections; Sputum; Statistics, Nonparametric; Tobramycin	1998
[Comparison of the pharmacokinetics of tobramycin administered in a single daily dose or in 3 doses in cystic fibrosis]. Pathologie-biologie, 1998, Volume: 46, Issue:6 Topics: Adolescent; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Humans; Pneumonia, Bacterial; Pseudomonas Infections; Tobramycin	1998
Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group. The New England journal of medicine, 1999, Jan-07, Volume: 340, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Bronchial Diseases; Child; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Hospitalization; Humans; Infusions, Intravenous; Male; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	1999
Comparison of a beta-lactam alone versus beta-lactam and an aminoglycoside for pulmonary exacerbation in cystic fibrosis. The Journal of pediatrics, 1999, Volume: 134, Issue:4 Topics: Adolescent; Analysis of Variance; Anti-Bacterial Agents; Azlocillin; Child; Cystic Fibrosis; DNA, Bacterial; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Penicillins; Pseudomonas aeruginosa; Respiratory Function Tests; Sputum; Tobramycin; Vital Capacity	1999
Effect of chronic intermittent administration of inhaled tobramycin on respiratory microbial flora in patients with cystic fibrosis. The Journal of infectious diseases, 1999, Volume: 179, Issue:5 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aspergillus; Bacteria; Candida albicans; Child; Cystic Fibrosis; Double-Blind Method; Drug Resistance, Microbial; Forced Expiratory Volume; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	1999
Are antipseudomonal antibiotics really beneficial in acute respiratory exacerbations of cystic fibrosis? Australian and New Zealand journal of medicine, 1999, Volume: 29, Issue:1 Topics: Acute Disease; Adult; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Infusions, Intravenous; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	1999
Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. The Journal of pediatrics, 1999, Volume: 135, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Humans; Pseudomonas Infections; Tobramycin	1999
Pulmonary gas exchange in cystic fibrosis: basal status and the effect of i.v. antibiotics and inhaled amiloride. The European respiratory journal, 1999, Volume: 14, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Amiloride; Anti-Bacterial Agents; Blood Flow Velocity; Blood Gas Analysis; Cross-Over Studies; Cystic Fibrosis; Diuretics; Female; Forced Expiratory Volume; Humans; Injections, Intravenous; Lactams; Male; Nebulizers and Vaporizers; Pulmonary Circulation; Single-Blind Method; Spirometry; Tobramycin; Tomography, X-Ray Computed; Treatment Outcome; Ventilation-Perfusion Ratio	1999
Activities of tobramycin and six other antibiotics against Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:12 Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Lactams; Microbial Sensitivity Tests; Phenotype; Pseudomonas aeruginosa; Tobramycin	1999
Savings in direct medical costs from the use of tobramycin solution for inhalation in patients with cystic fibrosis. Clinical therapeutics, 2000, Volume: 22, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cohort Studies; Costs and Cost Analysis; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Ontario; Pseudomonas Infections; Quebec; Tobramycin	2000
Aminoglycoside-resistance mechanisms for cystic fibrosis Pseudomonas aeruginosa isolates are unchanged by long-term, intermittent, inhaled tobramycin treatment. The Journal of infectious diseases, 2000, Volume: 181, Issue:3 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	2000
Pharmacokinetics of tobramycin in adults with cystic fibrosis: implications for once-daily administration. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Bayes Theorem; Cystic Fibrosis; Female; Humans; Lung Diseases; Male; Models, Biological; Pseudomonas Infections; Tobramycin	2000
Inhaled tobramycin and bronchial hyperactivity in cystic fibrosis. Pediatric pulmonology, 2000, Volume: 29, Issue:5 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Bronchoconstriction; Child; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Tobramycin	2000
Efficacy of once-daily tobramycin monotherapy for acute pulmonary exacerbations of cystic fibrosis: a preliminary study. Pediatric pulmonology, 2001, Volume: 31, Issue:5 Topics: Adolescent; Adult; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Child; Cystic Fibrosis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Pseudomonas Infections; Respiratory Function Tests; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome	2001
Microbiological and immunologic considerations with aerosolized drug delivery. Chest, 2001, Volume: 120, Issue:3 Suppl Topics: Aerosols; Child; Colony Count, Microbial; Cystic Fibrosis; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Long-Term Care; Microbial Sensitivity Tests; Nebulizers and Vaporizers; Opportunistic Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Stenotrophomonas maltophilia; Tobramycin	2001
Defining a pulmonary exacerbation in cystic fibrosis. The Journal of pediatrics, 2001, Volume: 139, Issue:3 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Lung Diseases; Male; Maximal Expiratory Flow Rate; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; ROC Curve; Surveys and Questionnaires; Tobramycin	2001
Serum and lower respiratory tract drug concentrations after tobramycin inhalation in young children with cystic fibrosis. The Journal of pediatrics, 2001, Volume: 139, Issue:4 Topics: Administration, Inhalation; Anti-Bacterial Agents; Bronchoalveolar Lavage; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Nebulizers and Vaporizers; Respiratory Mucosa; Tobramycin	2001
Long-term benefits of inhaled tobramycin in adolescent patients with cystic fibrosis. Chest, 2002, Volume: 121, Issue:1 Topics: Administration, Inhalation; Adolescent; Cystic Fibrosis; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Long-Term Care; Male; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2002
Once-daily tobramycin in the treatment of adult patients with cystic fibrosis. The European respiratory journal, 2002, Volume: 19, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Drug Administration Schedule; Forced Expiratory Volume; Humans; Lactams; Maximal Midexpiratory Flow Rate; Middle Aged; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Vital Capacity	2002
Eradication of initial Pseudomonas aeruginosa colonization in patients with cystic fibrosis. European journal of medical research, 2002, Feb-21, Volume: 7, Issue:2 Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Case-Control Studies; Ceftazidime; Child; Child, Preschool; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Humans; Infant; Injections, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2002
Effects of tobramycin solution for inhalation on global ratings of quality of life in patients with cystic fibrosis and Pseudomonas aeruginosa infection. Pediatric pulmonology, 2002, Volume: 33, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Logistic Models; Male; Nebulizers and Vaporizers; Odds Ratio; Outcome Assessment, Health Care; Pseudomonas Infections; Quality Indicators, Health Care; Retrospective Studies; Tobramycin	2002
A comparative study of ticarcillin plus tobramycin versus carbenicillin plus gentamicin for the treatment of serious infections due to gram-negative bacilli. The American journal of medicine, 1978, Volume: 64, Issue:6 Topics: Anti-Bacterial Agents; Carbenicillin; Cystic Fibrosis; Drug Therapy, Combination; Gentamicins; Gram-Negative Aerobic Bacteria; Humans; Kidney; Kidney Function Tests; Penicillin Resistance; Penicillins; Pneumonia; Pseudomonas Infections; Sepsis; Ticarcillin; Tobramycin	1978
Aerosol scintigraphy in the assessment of therapy for cystic fibrosis. Clinical nuclear medicine, 1992, Volume: 17, Issue:2 Topics: Adult; Bronchodilator Agents; Combined Modality Therapy; Cystic Fibrosis; Double-Blind Method; Female; Humans; Lung; Male; Prospective Studies; Pseudomonas Infections; Radionuclide Imaging; Technetium Tc 99m Pentetate; Ticarcillin; Tobramycin	1992
Dosage adjustment and clinical outcomes of long-term use of high-dose tobramycin in adult cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 1991, Volume: 28, Issue:4 Topics: Adult; Bacterial Infections; Bayes Theorem; Cystic Fibrosis; Female; Humans; Infusions, Intravenous; Kidney Diseases; Male; Pseudomonas Infections; Software; Tobramycin	1991
Comparison of 6 and 8 hourly tobramycin dosing intervals in treatment of pulmonary exacerbations in cystic fibrosis patients. The Pediatric infectious disease journal, 1991, Volume: 10, Issue:5 Topics: Adolescent; Adult; Cystic Fibrosis; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Pneumonia; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Tobramycin	1991
Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis. The Journal of allergy and clinical immunology, 1991, Volume: 87, Issue:1 Pt 1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Anti-Idiotypic; Azlocillin; Aztreonam; Ceftazidime; Child; Child, Preschool; Cross Reactions; Cystic Fibrosis; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Immunoglobulin G; Male; Piperacillin; Skin Tests; Ticarcillin; Tobramycin	1991
Bronchial response to nebulized antibiotics in children with cystic fibrosis. The European respiratory journal, 1990, Volume: 3, Issue:10 Topics: Administration, Inhalation; Adolescent; Analysis of Variance; Bronchoconstriction; Child; Child, Preschool; Cystic Fibrosis; Female; Forced Expiratory Volume; Histamine; Humans; Male; Nebulizers and Vaporizers; Ticarcillin; Tobramycin	1990
Reduction of sputum Pseudomonas aeruginosa density by antibiotics improves lung function in cystic fibrosis more than do bronchodilators and chest physiotherapy alone. The American review of respiratory disease, 1990, Volume: 141, Issue:4 Pt 1 Topics: Adult; Aerosols; Bronchodilator Agents; Colony Count, Microbial; Cystic Fibrosis; Drug Administration Schedule; Female; Humans; Male; Penicillins; Physical Therapy Modalities; Pseudomonas aeruginosa; Respiratory Function Tests; Spirometry; Sputum; Ticarcillin; Tobramycin	1990
Efficacy of inhaled tobramycin in cystic fibrosis. Journal of paediatrics and child health, 1990, Volume: 26, Issue:2 Topics: Acute Disease; Administration, Inhalation; Child; Clinical Trials as Topic; Cystic Fibrosis; Humans; Pseudomonas Infections; Retrospective Studies; Tobramycin	1990
Long-term effects of inhaled tobramycin in patients with cystic fibrosis colonized with Pseudomonas aeruginosa. Pediatric pulmonology, 1989, Volume: 7, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Bronchial Diseases; Child; Cystic Fibrosis; Drug Resistance, Microbial; Female; Humans; Male; Patient Compliance; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Sputum; Tobramycin	1989
Treatment of Pseudomonas lung infection in cystic fibrosis with piperacillin plus tobramycin versus ceftazidime monotherapy: preliminary communication. Pediatric pulmonology, 1989, Volume: 7, Issue:3 Topics: Ceftazidime; Chronic Disease; Cystic Fibrosis; Drug Combinations; Forced Expiratory Volume; Humans; Leukocyte Count; Lung Diseases; Neutrophils; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Tobramycin; Vital Capacity	1989
Safety of aerosol tobramycin administration for 3 months to patients with cystic fibrosis. Pediatric pulmonology, 1989, Volume: 7, Issue:4 Topics: Administration, Inhalation; Aerosols; Child; Clinical Trials as Topic; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Sputum; Time Factors; Tobramycin	1989
Controlled trial of aztreonam vs. tobramycin and azlocillin for acute pulmonary exacerbations of cystic fibrosis. The Pediatric infectious disease journal, 1988, Volume: 7, Issue:3 Topics: Adolescent; Azlocillin; Aztreonam; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Liver; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Respiratory Tract Infections; Sputum; Tobramycin; Transaminases	1988
A controlled trial of nebulized aminoglycoside and oral flucloxacillin versus placebo in the outpatient management of children with cystic fibrosis. British journal of diseases of the chest, 1987, Volume: 81, Issue:4 Topics: Administration, Inhalation; Administration, Oral; Adolescent; Child; Clinical Trials as Topic; Cloxacillin; Cystic Fibrosis; Double-Blind Method; Drug Therapy, Combination; Female; Floxacillin; Humans; Male; Pseudomonas Infections; Tobramycin	1987
Comparison of piperacillin alone versus piperacillin plus tobramycin for treatment of respiratory infections in children with cystic fibrosis. Pediatric pulmonology, 1988, Volume: 4, Issue:4 Topics: Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Half-Life; Humans; Infant; Piperacillin; Pseudomonas Infections; Random Allocation; Respiratory Tract Infections; Sputum; Tobramycin	1988
Immediate and prolonged clinical efficacy of ceftazidime versus ceftazidime plus tobramycin in chronic Pseudomonas aeruginosa infection in cystic fibrosis. Scandinavian journal of infectious diseases, 1986, Volume: 18, Issue:2 Topics: Adult; Ceftazidime; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Lung Diseases; Male; Pseudomonas Infections; Random Allocation; Time Factors; Tobramycin	1986
Ciprofloxacin versus tobramycin plus azlocillin in pulmonary exacerbations in adult patients with cystic fibrosis. The American journal of medicine, 1987, Apr-27, Volume: 82, Issue:4A Topics: Adult; Anti-Bacterial Agents; Azlocillin; Bacterial Infections; Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Therapy, Combination; Humans; Lung Diseases; Random Allocation; Therapeutic Equivalency; Tobramycin	1987
Ciprofloxacin: comparative data in cystic fibrosis. The American journal of medicine, 1987, Apr-27, Volume: 82, Issue:4A Topics: Adolescent; Adult; Azlocillin; Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Lung Diseases; Male; Penicillin Resistance; Pseudomonas Infections; Tobramycin	1987
Ciprofloxacin therapy in cystic fibrosis. The American journal of medicine, 1987, Apr-27, Volume: 82, Issue:4A Topics: Adolescent; Adult; Azlocillin; Child; Ciprofloxacin; Clinical Trials as Topic; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Lung Diseases; Male; Pseudomonas Infections; Tobramycin	1987
Comparison of cefoperazone sodium vs methicillin, ticarcillin, and tobramycin in treatment of pulmonary exacerbations in patients with cystic fibrosis. The Journal of pediatrics, 1985, Volume: 106, Issue:4 Topics: Adolescent; Adult; Bacterial Infections; Cefoperazone; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Methicillin; Penicillin Resistance; Penicillins; Pleural Effusion; Pseudomonas Infections; Random Allocation; Ticarcillin; Time Factors; Tobramycin	1985
Intensive treatment of pseudomonas chest infection in cystic fibrosis: a comparison of tobramycin and ticarcillin, and netilmicin and ticarcillin. Acta paediatrica Scandinavica, 1985, Volume: 74, Issue:1 Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; Drug Combinations; Female; Gentamicins; Humans; Lung Volume Measurements; Male; Netilmicin; Penicillins; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Ticarcillin; Tobramycin	1985
Comparison of cefpiramide (HR-810) and four anti-pseudomonal beta-lactam agents against pseudomonas isolates from children with cystic fibrosis. The Journal of antimicrobial chemotherapy, 1985, Volume: 15, Issue:5 Topics: Anti-Bacterial Agents; Cephalosporins; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Pseudomonas; Pseudomonas aeruginosa; Sputum; Tobramycin	1985

Other Studies

410 other study(ies) available for tobramycin and Cystic Fibrosis

Article	Year
Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Biofilms; Cefepime; Cephalosporins; Ciprofloxacin; Cystic Fibrosis; DNA-Binding Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; MutS DNA Mismatch-Binding Protein; Pseudomonas aeruginosa; Transcription Factors	2009
Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactams; Cystic Fibrosis; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum	2009
Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Cystic Fibrosis; DNA Repair; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Neutrophil Activation; Oxidation-Reduction; Oxidative Stress; Pseudomonas aeruginosa	2009
In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Aerosols; Anti-Bacterial Agents; Bacteria; Biofilms; Chronic Disease; Ciprofloxacin; Colony Count, Microbial; Cystic Fibrosis; Humans; Levofloxacin; Lung Diseases; Microbial Sensitivity Tests; Ofloxacin; Sputum	2010
Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Humans; Membrane Transport Proteins; Mutation; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation	2010
Efficacy of Problem-Solving Intervention to Improve Adherence in Adolescents and Adults with Cystic Fibrosis. The Israel Medical Association journal : IMAJ, 2021, Volume: 23, Issue:9 Topics: Adolescent; Adult; Anti-Bacterial Agents; Body Mass Index; Colistin; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Medication Adherence; Patient-Centered Care; Problem Solving; Quality of Life; Tobramycin; Young Adult	2021
Effect of iron chelation on anti-pseudomonal activity of doxycycline. International journal of antimicrobial agents, 2021, Volume: 58, Issue:6 Topics: Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Doxycycline; Drug Synergism; Humans; Iron Chelating Agents; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2021
Antimicrobial effects of Melaleuca alternifolia (tea tree) essential oil against biofilm-forming multidrug-resistant cystic fibrosis-associated Pseudomonas aeruginosa as a single agent and in combination with commonly nebulized antibiotics. Letters in applied microbiology, 2022, Volume: 75, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; Biofilms; Colistin; Cystic Fibrosis; Melaleuca; Microbial Sensitivity Tests; Oils, Volatile; Pseudomonas aeruginosa; Tea; Tea Tree Oil; Tobramycin; Trees	2022
Organic Acids and Their Salts Potentiate the Activity of Selected Antibiotics against Pseudomonas aeruginosa Biofilms Grown in a Synthetic Cystic Fibrosis Sputum Medium. Antimicrobial agents and chemotherapy, 2022, 01-18, Volume: 66, Issue:1 Topics: Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Salts; Sputum; Tobramycin	2022
Consideration of height-based tobramycin dosing regimens for the treatment of adult cystic fibrosis pulmonary exacerbations. British journal of clinical pharmacology, 2022, Volume: 88, Issue:5 Topics: Adult; Anti-Bacterial Agents; Computer Simulation; Cystic Fibrosis; Humans; Retrospective Studies; Tobramycin	2022
Are trough tobramycin concentrations taken from a central venous catheter accurate enough to safely use? Archives of disease in childhood, 2022, Volume: 107, Issue:5 Topics: Anti-Bacterial Agents; Central Venous Catheters; Cystic Fibrosis; Humans; Pseudomonas Infections; Tobramycin	2022
Effectiveness of different eradication treatment protocols for new-onset Pseudomonas aeruginosa in children with cystic fibrosis. Pediatric pulmonology, 2022, Volume: 57, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Ciprofloxacin; Clinical Protocols; Cystic Fibrosis; Humans; Observational Studies as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2022
Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA. Journal of bacteriology, 2022, 05-17, Volume: 204, Issue:5 Topics: Alginates; Anti-Bacterial Agents; Biofilms; Calcium; Cystic Fibrosis; Humans; Nucleic Acids; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Tobramycin	2022
Giving Drugs a Second Chance: Antibacterial and Antibiofilm Effects of Ciclopirox and Ribavirin against Cystic Fibrosis International journal of molecular sciences, 2022, Apr-30, Volume: 23, Issue:9 Topics: Anti-Bacterial Agents; Biofilms; Ciclopirox; Cystic Fibrosis; Dactinomycin; Drug Repositioning; Extracellular Polymeric Substance Matrix; Fluorouracil; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Ribavirin; Tobramycin	2022
Acute kidney injury in cystic fibrosis patients treated with intravenous colistimethate sodium or tobramycin. The Journal of antimicrobial chemotherapy, 2022, 08-25, Volume: 77, Issue:9 Topics: Acute Kidney Injury; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Humans; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tobramycin; Vancomycin	2022
Development of excipients free inhalable co-spray-dried tobramycin and diclofenac formulations for cystic fibrosis using two and three fluid nozzles. International journal of pharmaceutics, 2022, Aug-25, Volume: 624 Topics: Administration, Inhalation; Cystic Fibrosis; Diclofenac; Dry Powder Inhalers; Excipients; Humans; Particle Size; Powders; Respiratory Aerosols and Droplets; Tobramycin	2022
Nitric oxide inhibits alginate biosynthesis in Pseudomonas aeruginosa and increases its sensitivity to tobramycin by downregulating algU gene expression. Nitric oxide : biology and chemistry, 2022, 11-01, Volume: 128 Topics: Alginates; Bacterial Proteins; Cystic Fibrosis; Gene Expression; Humans; Nitric Oxide; Pseudomonas aeruginosa; Tobramycin	2022
New Recommendations of a Height-Based Dosing Regimen of Tobramycin for Cystic Fibrosis in Adults: A Population Pharmacokinetic Analysis. Therapeutic drug monitoring, 2023, 04-01, Volume: 45, Issue:2 Topics: Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Cystic Fibrosis; Humans; Retrospective Studies; Tobramycin	2023
Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung. Infection and immunity, 2022, 11-17, Volume: 90, Issue:11 Topics: Animals; Anti-Bacterial Agents; Cystic Fibrosis; Inflammation; Lung; Rats; Staphylococcal Infections; Staphylococcus aureus; Tobramycin	2022
Personalized tobramycin dosing in children with cystic fibrosis: a comparative clinical evaluation of log-linear and Bayesian methods. The Journal of antimicrobial chemotherapy, 2022, 11-28, Volume: 77, Issue:12 Topics: Anti-Bacterial Agents; Bayes Theorem; Child; Cystic Fibrosis; Drug Monitoring; Humans; Pseudomonas Infections; Tobramycin	2022
Impact of N-Acetylcysteine and Antibiotics Against Single and Dual Species Biofilms of Pseudomonas aeruginosa and Achromobacter xylosoxidans. Current microbiology, 2022, Nov-25, Volume: 80, Issue:1 Topics: Acetylcysteine; Achromobacter denitrificans; Animals; Anti-Bacterial Agents; Aztreonam; Biofilms; Caenorhabditis elegans; Ciprofloxacin; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Tobramycin	2022
The Effects of Antibiotic Combination Treatments on Pseudomonas aeruginosa Tolerance Evolution and Coexistence with Stenotrophomonas maltophilia. Microbiology spectrum, 2022, 12-21, Volume: 10, Issue:6 Topics: Anti-Bacterial Agents; Ciprofloxacin; Colistin; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Stenotrophomonas maltophilia; Tobramycin	2022
Effects of long-term tobramycin inhalation solution (TIS) once daily on exacerbation rate in patients with non-cystic fibrosis bronchiectasis. Respiratory research, 2022, Dec-03, Volume: 23, Issue:1 Topics: Adolescent; Bronchiectasis; Cystic Fibrosis; Fibrosis; Humans; Quality of Life; Tobramycin	2022
Pseudomonas aeruginosa aggregation and Psl expression in sputum is associated with antibiotic eradication failure in children with cystic fibrosis. Scientific reports, 2022, 12-12, Volume: 12, Issue:1 Topics: Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	2022
Incidence and associated risk factors for systemic drug levels with inhaled aminoglycoside therapy. The Journal of antimicrobial chemotherapy, 2023, 02-01, Volume: 78, Issue:2 Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Incidence; Renal Insufficiency, Chronic; Retrospective Studies; Tobramycin	2023
Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system. eLife, 2023, 01-20, Volume: 12 Topics: Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Humans; Phenotype; Pseudomonas aeruginosa; Staphylococcal Infections; Tobramycin	2023
Development and Evaluation of a Height-Based Tobramycin Initial Dosing Nomogram for the Treatment of Adult Cystic Fibrosis Pulmonary Exacerbations. Therapeutic drug monitoring, 2023, 04-01, Volume: 45, Issue:2 Topics: Adult; Anti-Bacterial Agents; Body Weight; Cystic Fibrosis; Humans; Nomograms; Tobramycin	2023
Efficacy of Antibiotic Eradication Therapy of Early Annals of the American Thoracic Society, 2023, Volume: 20, Issue:6 Topics: Anti-Bacterial Agents; Arthritis, Psoriatic; Child; Ciliary Motility Disorders; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2023
Comparison of Three Eradication Treatment Protocols for Pseudomonas Aeruginosa in Children and Adolescents with Cystic Fibrosis. Klinische Padiatrie, 2023, Volume: 235, Issue:2 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Clinical Protocols; Cystic Fibrosis; Humans; Observational Studies as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2023
Comparing the Efficacy and Safety of Nebulized Gentamicin Plus Amikacin Current drug safety, 2024, Volume: 19, Issue:1 Topics: Administration, Inhalation; Amikacin; Anti-Bacterial Agents; Cross-Sectional Studies; Cystic Fibrosis; Gentamicins; Humans; Pseudomonas Infections; Tobramycin	2024
In the Clear: Long-term pulmonary function benefits associated with Pseudomonas aeruginosa eradication. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2023, Volume: 22, Issue:1 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2023
Chronic inhaled antibiotic therapy in people with cystic fibrosis with Pseudomonas aeruginosa infection in Germany. Pulmonary pharmacology & therapeutics, 2023, Volume: 80 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Child; Colistin; Cystic Fibrosis; Germany; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2023
Exploration of the relationship between cumulative exposure to tobramycin and ototoxicity in patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2023, Volume: 22, Issue:5 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Hearing Loss; Humans; Ototoxicity; Retrospective Studies; Tobramycin	2023
Determining effects of nitrate, arginine, and ferrous on antibiotic recalcitrance of clinical strains of Pseudomonas aeruginosa in biofilm-inspired alginate encapsulates. Annals of clinical microbiology and antimicrobials, 2023, Jul-20, Volume: 22, Issue:1 Topics: Alginates; Amikacin; Anti-Bacterial Agents; Arginine; Biofilms; Ciprofloxacin; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Nitrates; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2023
Limited effects of azithromycin on the oropharyngeal microbiome in children with CF and early pseudomonas infection. BMC microbiology, 2023, 10-27, Volume: 23, Issue:1 Topics: Administration, Inhalation; Anti-Bacterial Agents; Azithromycin; Bacteria; Child; Cystic Fibrosis; Humans; Microbiota; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2023
Home videos of cystic fibrosis patients using tobramycin inhalation powder: Relation of flow and cough. Pediatric pulmonology, 2019, Volume: 54, Issue:11 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cough; Cystic Fibrosis; Female; Humans; Male; Powders; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Video Recording; Young Adult	2019
Unwarranted use of intravenous aminoglycosides at UK paediatric cystic fibrosis centres. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2019, Volume: 18, Issue:6 Topics: Administration, Intravenous; Aminoglycosides; Anti-Bacterial Agents; Child; Cystic Fibrosis; Health Care Surveys; Hearing Loss; Humans; Inappropriate Prescribing; Kidney Diseases; Pediatrics; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; United Kingdom	2019
Genomic and phenotypic comparison of environmental and patient-derived isolates of Journal of medical microbiology, 2019, Volume: 68, Issue:11 Topics: Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Bacterial; Environmental Microbiology; Genomics; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2019
Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis. Journal of controlled release : official journal of the Controlled Release Society, 2019, 11-28, Volume: 314 Topics: Acetylcysteine; Administration, Inhalation; Animals; Anti-Bacterial Agents; Azithromycin; Biofilms; Ciprofloxacin; Cystic Fibrosis; Drug Stability; Drug Storage; Expectorants; Horses; Mucus; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2019
Pulmonary Outcomes Associated with Long-Term Azithromycin Therapy in Cystic Fibrosis. American journal of respiratory and critical care medicine, 2020, 02-15, Volume: 201, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Aztreonam; Child; Cohort Studies; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Retrospective Studies; Tobramycin; Young Adult	2020
Serum-Associated Antibiotic Tolerance in Pediatric Clinical Isolates of Pseudomonas aeruginosa. Journal of the Pediatric Infectious Diseases Society, 2020, Dec-31, Volume: 9, Issue:6 Topics: Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2020
In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2020, Volume: 19, Issue:6 Topics: Alginates; Animals; Biofilms; Cystic Fibrosis; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Pseudomonas aeruginosa; Tobramycin	2020
Antibacterial activity of iron oxide, iron nitride, and tobramycin conjugated nanoparticles against Pseudomonas aeruginosa biofilms. Journal of nanobiotechnology, 2020, Feb-18, Volume: 18, Issue:1 Topics: Alginates; Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Drug Carriers; Drug Design; Drug Therapy, Combination; Ferric Compounds; Humans; Magnetic Fields; Magnetite Nanoparticles; Microbial Sensitivity Tests; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Silver; Surface Properties; Tobramycin	2020
Effect of Inspiratory Maneuvers on Lung Deposition of Tobramycin Inhalation Powder: A Modeling Study. Journal of aerosol medicine and pulmonary drug delivery, 2020, Volume: 33, Issue:2 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Computer Simulation; Cystic Fibrosis; Female; Humans; Hydrodynamics; Lung; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas Infections; Tissue Distribution; Tobramycin; Young Adult	2020
Anti-Infectives Restore ORKAMBI Biomolecules, 2020, 02-19, Volume: 10, Issue:2 Topics: Aminophenols; Aminopyridines; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Benzodioxoles; Bronchi; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Combinations; Humans; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones; Tobramycin	2020
Disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate lyase enhances pathogen eradication by antibiotics. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2021, Volume: 20, Issue:2 Topics: Biofilms; Ciprofloxacin; Cystic Fibrosis; Drug Synergism; Polysaccharide-Lyases; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2021
Effects of CFTR modulators on pharmacokinetics of tobramycin during acute pulmonary exacerbations in the pediatric cystic fibrosis population. Pediatric pulmonology, 2020, Volume: 55, Issue:10 Topics: Administration, Intravenous; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Progression; Drug Interactions; Female; Humans; Male; Tobramycin	2020
Maintenance tobramycin primarily affects untargeted bacteria in the CF sputum microbiome. Thorax, 2020, Volume: 75, Issue:9 Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Child; Cystic Fibrosis; Forced Expiratory Volume; Humans; Maintenance Chemotherapy; Metagenome; Microbiota; Middle Aged; Severity of Illness Index; Sputum; Time Factors; Tobramycin; Young Adult	2020
Prospective cohort study of ototoxicity in persons with cystic fibrosis following a single course of intravenous tobramycin. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2021, Volume: 20, Issue:2 Topics: Administration, Intravenous; Adolescent; Adult; Aminoglycosides; Audiometry, Pure-Tone; Cystic Fibrosis; Female; Hearing Loss; Humans; Male; Middle Aged; Ototoxicity; Prospective Studies; Tobramycin	2021
Effect of Concomitant Azithromycin and Tobramycin Use on Cystic Fibrosis Pulmonary Exacerbation Treatment. Annals of the American Thoracic Society, 2021, Volume: 18, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Child; Cystic Fibrosis; Humans; Retrospective Studies; Tobramycin; Young Adult	2021
Incidence of nephrotoxicity with prolonged aminoglycoside exposure in patients with cystic fibrosis. Pediatric pulmonology, 2020, Volume: 55, Issue:12 Topics: Acute Kidney Injury; Adolescent; Adult; Age Factors; Anti-Bacterial Agents; Child; Child, Preschool; Colistin; Cystic Fibrosis; Female; Humans; Incidence; Infant; Male; Middle Aged; Piperacillin, Tazobactam Drug Combination; Pseudomonas Infections; Retrospective Studies; Risk Factors; Tobramycin; Vancomycin; Young Adult	2020
The cystic fibrosis gut as a potential source of multidrug resistant pathogens. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2021, Volume: 20, Issue:3 Topics: Adult; Anti-Bacterial Agents; Case-Control Studies; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Feces; Female; Gastrointestinal Microbiome; Humans; Male; Metagenomics; Microbial Sensitivity Tests; Tobramycin	2021
Ototoxicity in cystic fibrosis patients receiving intravenous tobramycin for acute pulmonary exacerbation: Ototoxicity following tobramycin treatment. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2021, Volume: 20, Issue:2 Topics: Administration, Intravenous; Adolescent; Adult; Aminoglycosides; Audiometry, Pure-Tone; Cystic Fibrosis; Female; Hearing Loss; Humans; Male; Middle Aged; Ototoxicity; Respiratory Tract Infections; Symptom Flare Up; Tobramycin	2021
Azithromycin and Tobramycin Therapy in Cystic Fibrosis Pulmonary Exacerbations: Less Is More? Annals of the American Thoracic Society, 2021, Volume: 18, Issue:2 Topics: Anti-Bacterial Agents; Azithromycin; Cystic Fibrosis; Humans; Pseudomonas Infections; Tobramycin	2021
Failed Eradication Therapy of New-Onset Pseudomonas aeruginosa Infections in Children With Cystic Fibrosis Is Associated With Bacterial Resistance to Neutrophil Functions. The Journal of infectious diseases, 2022, 06-01, Volume: 225, Issue:11 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Humans; Neutrophils; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2022
Rates of adverse and serious adverse events in children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2021, Volume: 20, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Infant; Male; Seasons; Severity of Illness Index; Tobramycin	2021
Tobramycin and vestibulotoxicity: retrospective analysis of four cases. European journal of hospital pharmacy : science and practice, 2022, Volume: 29, Issue:e1 Topics: Cystic Fibrosis; Humans; Retrospective Studies; Tobramycin	2022
Tobramycin and Colistin display anti-inflammatory properties in CuFi-1 cystic fibrosis cell line. European journal of pharmacology, 2021, Jul-05, Volume: 902 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Colistin; Cystic Fibrosis; Drug Combinations; Humans; Ibuprofen; Inflammation; Interleukin-8; Lipopolysaccharides; Pseudomonas aeruginosa; Tobramycin	2021
Bayesian Forecasting for Intravenous Tobramycin Dosing in Adults With Cystic Fibrosis Using One Versus Two Serum Concentrations in a Dosing Interval. Therapeutic drug monitoring, 2021, 08-01, Volume: 43, Issue:4 Topics: Adult; Anti-Bacterial Agents; Bayes Theorem; Cystic Fibrosis; Drug Administration Schedule; Humans; Tobramycin	2021
Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis-Related Pseudomonas aeruginosa Biofilms. Small (Weinheim an der Bergstrasse, Germany), 2021, Volume: 17, Issue:24 Topics: Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Humans; Liquid Crystals; Microbial Sensitivity Tests; Nanoparticles; Pseudomonas aeruginosa; Tobramycin	2021
The Role of Suboptimal Concentrations of Nebulized Tobramycin in Driving Antimicrobial Resistance in Respiratory care, 2021, Volume: 66, Issue:9 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2021
Impact of a pharmacy technician and pharmacist on time to inhaled tobramycin therapy in a pediatric cystic fibrosis clinic. Pediatric pulmonology, 2021, Volume: 56, Issue:9 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Pharmacists; Pharmacy Technicians; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2021
Comparison of the predictive value of area under the curve versus maximum serum concentration of intravenous tobramycin in cystic fibrosis patients treated for an acute pulmonary exacerbation. Pediatric pulmonology, 2021, Volume: 56, Issue:10 Topics: Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2021
Early Antibiotics in Cystic Fibrosis: Lessons from the Cystic Fibrosis Pig Model. American journal of respiratory and critical care medicine, 2021, 09-15, Volume: 204, Issue:6 Topics: Animals; Anti-Bacterial Agents; Cystic Fibrosis; Pseudomonas Infections; Swine; Tobramycin	2021
The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis. NPJ biofilms and microbiomes, 2021, 08-04, Volume: 7, Issue:1 Topics: Adhesins, Bacterial; Anti-Bacterial Agents; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Proteins; Biofilms; Child; Cystic Fibrosis; Extracellular Polymeric Substance Matrix; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory System; Tobramycin	2021
Pharmacokinetic modelling to predict risk of ototoxicity with intravenous tobramycin treatment in cystic fibrosis. The Journal of antimicrobial chemotherapy, 2021, 10-11, Volume: 76, Issue:11 Topics: Aminoglycosides; Anti-Bacterial Agents; Bayes Theorem; Cystic Fibrosis; Humans; Ototoxicity; Tobramycin	2021
Pseudomonas aeruginosa eradication: Finally moving the needle? Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:3 Topics: Child; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2017
Piperacillin-tazobactam versus cefepime incidence of acute kidney injury in combination with vancomycin and tobramycin in pediatric cystic fibrosis patients. Pediatric pulmonology, 2017, Volume: 52, Issue:8 Topics: Acute Kidney Injury; Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Hospitalization; Humans; Incidence; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tobramycin; Vancomycin	2017
Economic Evaluation of Tobramycin Inhalation Powder for the Treatment of Chronic Pulmonary Pseudomonas aeruginosa Infection in Patients with Cystic Fibrosis. Clinical drug investigation, 2017, Volume: 37, Issue:8 Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Chronic Disease; Cost-Benefit Analysis; Cystic Fibrosis; Economics, Pharmaceutical; Female; Humans; Male; Middle Aged; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Young Adult	2017
Novel glycopolymer sensitizes Burkholderia cepacia complex isolates from cystic fibrosis patients to tobramycin and meropenem. PloS one, 2017, Volume: 12, Issue:6 Topics: Acetylglucosamine; Anti-Bacterial Agents; Burkholderia cepacia complex; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Meropenem; Microbial Sensitivity Tests; Thienamycins; Tobramycin	2017
Macrophage migration inhibitory factor enhances FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017, Volume: 31, Issue:11 Topics: Animals; Biofilms; Cystic Fibrosis; Disease Models, Animal; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Mice; Pseudomonas aeruginosa; Recombinant Proteins; Tobramycin	2017
An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12 Topics: Anti-Bacterial Agents; Azithromycin; Biofilms; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Therapy, Combination; Fumarates; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	2017
Patient-specific modelling of regional tobramycin concentration levels in airways of patients with cystic fibrosis: can we dose once daily? The Journal of antimicrobial chemotherapy, 2017, Dec-01, Volume: 72, Issue:12 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Computer Simulation; Cystic Fibrosis; Drug Delivery Systems; Female; Humans; Male; Microbial Sensitivity Tests; Pneumonia, Bacterial; Pseudomonas Infections; Respiratory System; Retrospective Studies; Tobramycin	2017
Nano into Micro Formulations of Tobramycin for the Treatment of Pseudomonas aeruginosa Infections in Cystic Fibrosis. Biomacromolecules, 2017, Dec-11, Volume: 18, Issue:12 Topics: Anti-Bacterial Agents; Biofilms; Bronchi; Cells, Cultured; Chemistry, Pharmaceutical; Cystic Fibrosis; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Dry Powder Inhalers; Epithelial Cells; Humans; Nanoparticles; Particle Size; Polyelectrolytes; Polymers; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	2017
Evaluation of Tobramycin Exposure Predictions in Three Bayesian Forecasting Programmes Compared with Current Clinical Practice in Children and Adults with Cystic Fibrosis. Clinical pharmacokinetics, 2018, Volume: 57, Issue:8 Topics: Adult; Anti-Bacterial Agents; Area Under Curve; Bayes Theorem; Child; Cystic Fibrosis; Drug Monitoring; Humans; Precision Medicine; Predictive Value of Tests; Tobramycin	2018
Detectable Concentrations of Inhaled Tobramycin in Critically Ill Children Without Cystic Fibrosis: Should Routine Monitoring Be Recommended? Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2017, Volume: 18, Issue:12 Topics: Acute Kidney Injury; Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Critical Illness; Cystic Fibrosis; Drug Monitoring; Female; Humans; Infant; Infant, Newborn; Male; Retrospective Studies; Tobramycin	2017
Bayesian Estimation of Tobramycin Exposure in Patients with Cystic Fibrosis: an Update. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:3 Topics: Anti-Bacterial Agents; Bayes Theorem; Cystic Fibrosis; Humans; Pseudomonas aeruginosa; Tobramycin	2018
Health insurance and use of recommended routine care in adults with cystic fibrosis. The clinical respiratory journal, 2018, Volume: 12, Issue:5 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Deoxyribonuclease I; Female; Humans; Insurance Coverage; Insurance, Health; Male; Patient Care Bundles; Patient Compliance; Pseudomonas aeruginosa; Recombinant Proteins; Respiratory Therapy; Social Class; Tobramycin; United States	2018
Implementation of a successful eradication protocol for Burkholderia Cepacia complex in cystic fibrosis patients. BMC pulmonary medicine, 2018, Feb-14, Volume: 18, Issue:1 Topics: Administration, Inhalation; Administration, Intravenous; Administration, Oral; Adult; Anti-Bacterial Agents; Azithromycin; Burkholderia cepacia complex; Burkholderia Infections; Ceftazidime; Clinical Protocols; Cohort Studies; Consolidation Chemotherapy; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Pneumonia, Bacterial; Retrospective Studies; Tobramycin; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult	2018
PEGylation of Tobramycin Improves Mucus Penetration and Antimicrobial Activity against Pseudomonas aeruginosa Biofilms in Vitro. Molecular pharmaceutics, 2018, 04-02, Volume: 15, Issue:4 Topics: Animals; Anti-Bacterial Agents; Biofilms; Chickens; Cystic Fibrosis; Humans; Lung; Microbial Sensitivity Tests; Mucus; Polyethylene Glycols; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Swine; Tobramycin	2018
Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin. Scientific reports, 2018, 03-23, Volume: 8, Issue:1 Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Biomarkers; Child; Cystic Fibrosis; Female; Hepatitis A Virus Cellular Receptor 1; Humans; Lipocalin-2; Male; Prospective Studies; Tobramycin	2018
Treatment compliance in cystic fibrosis patients with chronic Pseudomonas aeruginosa infection treated with tobramycin inhalation powder: The FREE study. Respiratory medicine, 2018, Volume: 138 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Dry Powder Inhalers; Humans; Longitudinal Studies; Medication Adherence; Opportunistic Infections; Patient Satisfaction; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; Young Adult	2018
Pharmacokinetics of Continuous Infusion Beta-lactams in the Treatment of Acute Pulmonary Exacerbations in Adult Patients With Cystic Fibrosis. Chest, 2018, Volume: 154, Issue:5 Topics: Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Disease Progression; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Retrospective Studies; Symptom Flare Up; Tobramycin	2018
Polyester-based particles to overcome the obstacles of mucus and biofilms in the lung for tobramycin application under static and dynamic fluidic conditions. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 131 Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia complex; Cystic Fibrosis; Drug Carriers; Humans; Lung; Materials Testing; Microbial Sensitivity Tests; Mucus; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Pseudomonas aeruginosa; Tobramycin	2018
Monitoring of Tobramycin Exposure: What is the Best Estimation Method and Sampling Time for Clinical Practice? Clinical pharmacokinetics, 2019, Volume: 58, Issue:3 Topics: Administration, Intravenous; Adolescent; Adult; Algorithms; Anti-Bacterial Agents; Area Under Curve; Bayes Theorem; Case-Control Studies; Clinical Decision-Making; Cystic Fibrosis; Drug Monitoring; Humans; Practice Patterns, Physicians'; Predictive Value of Tests; Time Factors; Tobramycin; Young Adult	2019
Individualizing piperacillin/tazobactam dosing in adult patients with cystic fibrosis: can tobramycin measurements help? The Journal of antimicrobial chemotherapy, 2019, 01-01, Volume: 74, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Tobramycin; Young Adult	2019
Intermittent inhaled tobramycin and systemic cytokines response in CF patients with Pseudomonas aeruginosa. Clinical and investigative medicine. Medecine clinique et experimentale, 2018, 09-30, Volume: 41, Issue:3 Topics: Adolescent; Adult; Child; Cystic Fibrosis; Cytokines; Female; Humans; Interleukin-6; Male; Prospective Studies; Pseudomonas aeruginosa; Tobramycin; Young Adult	2018
Decreased Pseudomonas aeruginosa detection in children after separation of pediatric from adult cystic fibrosis clinics: A single center experience. Pediatric pulmonology, 2018, Volume: 53, Issue:12 Topics: Administration, Inhalation; Adult; Ambulatory Care Facilities; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Humans; Infant, Newborn; Male; Minnesota; Neonatal Screening; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2018
Tobramycin reduces key virulence determinants in the proteome of Pseudomonas aeruginosa outer membrane vesicles. PloS one, 2019, Volume: 14, Issue:1 Topics: Bacterial Proteins; Bronchi; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exopeptidases; Humans; Immunity, Innate; Proteomics; Pseudomonas aeruginosa; Secretory Vesicles; Tobramycin; Virulence	2019
Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from cystic fibrosis patients. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2019, Volume: 18, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Adhesion; Bacteriological Techniques; Cystic Fibrosis; Humans; Hyperbaric Oxygenation; Lung; Models, Biological; Neutrophils; Oxygen; Pseudomonas aeruginosa; Respiratory Tract Infections; Tobramycin	2019
No benefit of longer eradication therapy of Pseudomonas aeruginosa primoinfections in pediatric cystic fibrosis. BMC research notes, 2019, Mar-04, Volume: 12, Issue:1 Topics: Anti-Bacterial Agents; Child; Ciprofloxacin; Clinical Protocols; Cystic Fibrosis; Female; Humans; Male; Outcome and Process Assessment, Health Care; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Time Factors; Tobramycin	2019
Oral Azithromycin Use and the Recovery of Lung Function from Pulmonary Exacerbations Treated with Intravenous Tobramycin or Colistimethate in Adults with Cystic Fibrosis. Annals of the American Thoracic Society, 2019, Volume: 16, Issue:7 Topics: Administration, Inhalation; Administration, Intravenous; Adult; Anti-Bacterial Agents; Azithromycin; Colistin; Cystic Fibrosis; Disease Progression; Female; Forced Expiratory Volume; Humans; Logistic Models; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin; Young Adult	2019
Oral Azithromycin and Response to Pulmonary Exacerbations Treated with Intravenous Tobramycin in Children with Cystic Fibrosis. Annals of the American Thoracic Society, 2019, Volume: 16, Issue:7 Topics: Administration, Intravenous; Adolescent; Anti-Bacterial Agents; Azithromycin; Child; Cystic Fibrosis; Disease Progression; Female; Forced Expiratory Volume; Humans; Logistic Models; Male; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2019
Cystic fibrosis in the modern therapeutic era: Give the shower a thought! Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2019, Volume: 18, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Equipment Contamination; Equipment Failure; Equipment Failure Analysis; Humans; Nebulizers and Vaporizers; Pseudomonas Infections; Self Care; Tobramycin	2019
Nanometric ion pair complexes of tobramycin forming microparticles for the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. International journal of pharmaceutics, 2019, May-30, Volume: 563 Topics: Anti-Bacterial Agents; Biofilms; Cell Line; Cystic Fibrosis; Drug Carriers; Humans; Mucus; Nanoparticles; Peptides; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2019
Optimizing Estimated Glomerular Filtration Rate to Support Adult to Pediatric Pharmacokinetic Bridging Studies in Patients with Cystic Fibrosis. Clinical pharmacokinetics, 2019, Volume: 58, Issue:10 Topics: Adolescent; Adult; Aging; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Female; Glomerular Filtration Rate; Humans; Infant; Male; Middle Aged; Models, Biological; Tobramycin; Young Adult	2019
A real world evaluation of the long-term efficacy of strategies to prevent chronic Pseudomonas aeruginosa pulmonary infection in children with cystic fibrosis. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 85 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Cohort Studies; Cystic Fibrosis; Female; Humans; Infant; Infant, Newborn; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Retrospective Studies; Tobramycin	2019
Thorax, 2019, Volume: 74, Issue:8 Topics: Anti-Bacterial Agents; Bronchoalveolar Lavage; Ceftazidime; Child, Preschool; Ciprofloxacin; Clavulanic Acids; Cross-Sectional Studies; Cystic Fibrosis; Female; Humans; Infant; Longitudinal Studies; Male; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Pulmonary Aspergillosis; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Ticarcillin; Tobramycin	2019
What is the recommended amikacin dosing for cystic fibrosis patients with acute pulmonary exacerbations? Pediatric pulmonology, 2019, Volume: 54, Issue:11 Topics: Adult; Amikacin; Aminoglycosides; Cystic Fibrosis; Humans; Monte Carlo Method; Tobramycin	2019
Pharmacokinetic/pharmacodynamic analysis of weight- and height-scaled tobramycin dosage regimens for patients with cystic fibrosis. The Journal of antimicrobial chemotherapy, 2019, 08-01, Volume: 74, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Body Height; Body Weight; Cystic Fibrosis; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Statistical; Plasma; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Young Adult	2019
Influence of multiple courses of therapy on aminoglycoside clearance in adult patients with cystic fibrosis. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:6 Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Body Height; Body Weight; Cystic Fibrosis; Female; Fluorescence Polarization Immunoassay; Gentamicins; Humans; Infusions, Intravenous; Male; Middle Aged; Models, Statistical; Reproducibility of Results; Tobramycin; Young Adult	2013
Tobramycin is a suppressor of premature termination codons. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:6 Topics: Anti-Bacterial Agents; Codon, Nonsense; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genes, Reporter; Gentamicins; Models, Genetic; Nonsense Mediated mRNA Decay; Saccharomyces cerevisiae; Suppression, Genetic; Tobramycin	2013
New co-spray-dried tobramycin nanoparticles-clarithromycin inhaled powder systems for lung infection therapy in cystic fibrosis patients. Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Clarithromycin; Cystic Fibrosis; Desiccation; Drug Delivery Systems; Humans; Lung; Lung Diseases; Nanoparticles; Powders; Respiratory Tract Infections; Solubility; Tobramycin	2013
Carrier-free combination for dry powder inhalation of antibiotics in the treatment of lung infections in cystic fibrosis. International journal of pharmaceutics, 2013, Jul-15, Volume: 451, Issue:1-2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Bacterial Infections; Clarithromycin; Crystallization; Cystic Fibrosis; Drug Combinations; Drug Compounding; Drug Synergism; Dry Powder Inhalers; Lung; Lung Diseases; Microscopy, Electron, Scanning; Particle Size; Powders; Tissue Distribution; Tobramycin; X-Ray Diffraction	2013
The use of doripenem in pediatric cystic fibrosis patients in case of meropenem shortages. Pediatric pulmonology, 2014, Volume: 49, Issue:3 Topics: Adolescent; Anti-Bacterial Agents; Burkholderia cenocepacia; Burkholderia Infections; Carbapenems; Child; Cystic Fibrosis; Disease Progression; Doripenem; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Pseudomonas stutzeri; Rhodospirillaceae; Thienamycins; Tobramycin; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination	2014
Investigating the role of matrix components in protection of Burkholderia cepacia complex biofilms against tobramycin. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:1 Topics: Anti-Bacterial Agents; beta-Glucans; Biofilms; Burkholderia cepacia; Burkholderia Infections; Cystic Fibrosis; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Polysaccharides, Bacterial; Tobramycin; Virulence; Virulence Factors	2014
Resistance development of cystic fibrosis respiratory pathogens when exposed to fosfomycin and tobramycin alone and in combination under aerobic and anaerobic conditions. PloS one, 2013, Volume: 8, Issue:7 Topics: Adult; Aerobiosis; Anaerobiosis; Anti-Bacterial Agents; Culture Media; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Fosfomycin; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mutation Rate; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Tobramycin	2013
Fosfomycin and tobramycin in combination downregulate nitrate reductase genes narG and narH, resulting in increased activity against Pseudomonas aeruginosa under anaerobic conditions. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:11 Topics: Anaerobiosis; Anti-Bacterial Agents; Bacterial Proteins; Cystic Fibrosis; Drug Combinations; Fosfomycin; Gene Expression Regulation, Bacterial; Humans; Isoenzymes; Lung; Microbial Sensitivity Tests; Nitrate Reductase; Nitrates; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Transcription, Genetic	2013
Clinical use of tobramycin inhalation solution (TOBI®) shows sustained improvement in FEV1 in cystic fibrosis. Pediatric pulmonology, 2014, Volume: 49, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Tobramycin; Treatment Outcome; Young Adult	2014
Pharmacodynamic target attainment with high-dose extended-interval tobramycin therapy in patients with cystic fibrosis. Journal of chemotherapy (Florence, Italy), 2014, Volume: 26, Issue:2 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Guideline Adherence; Humans; Male; Retrospective Studies; Tobramycin	2014
Effectiveness of inhaled tobramycin in eradicating Pseudomonas aeruginosa in children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Risk Factors; Secondary Prevention; Tobramycin; Treatment Outcome	2014
The cost effectiveness of dry powder antibiotics for the treatment of Pseudomonas aeruginosa in patients with cystic fibrosis. PharmacoEconomics, 2014, Volume: 32, Issue:2 Topics: Adult; Anti-Bacterial Agents; Colistin; Cost-Benefit Analysis; Cystic Fibrosis; Decision Support Techniques; Dry Powder Inhalers; Humans; Models, Economic; Pneumonia, Bacterial; Probability; Pseudomonas aeruginosa; Pseudomonas Infections; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Survival Analysis; Tobramycin; Young Adult	2014
Mannitol enhances antibiotic sensitivity of persister bacteria in Pseudomonas aeruginosa biofilms. PloS one, 2013, Volume: 8, Issue:12 Topics: Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Diuretics, Osmotic; Drug Resistance, Bacterial; Humans; Mannitol; Mutation; Pneumonia, Bacterial; Pseudomonas aeruginosa; Tobramycin	2013
Pharmacokinetic and pharmacodynamic optimisation of intravenous tobramycin dosing among children with cystic fibrosis. Journal of pharmacokinetics and pharmacodynamics, 2014, Volume: 41, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; Area Under Curve; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Injections, Intravenous; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	2014
NICE guidance on colistimethate sodium and tobramycin for pseudomonas lung infection in cystic fibrosis. The Lancet. Respiratory medicine, 2013, Volume: 1, Issue:2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Clinical Trials as Topic; Colistin; Cystic Fibrosis; Drug Monitoring; Drug Therapy, Combination; Dry Powder Inhalers; Humans; Practice Guidelines as Topic; Pseudomonas Infections; Respiratory Function Tests; Respiratory Tract Infections; State Medicine; Tobramycin; United Kingdom	2013
Safety of inhaled (Tobi®) and intravenous tobramycin in young children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:4 Topics: Administration, Inhalation; Administration, Intravenous; Anti-Bacterial Agents; Child, Preschool; Cystic Fibrosis; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin; Treatment Outcome	2014
Related factors of dental caries and molar incisor hypomineralisation in a group of children with cystic fibrosis. European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2014, Volume: 15, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Buffers; Child; Cohort Studies; Cystic Fibrosis; Dental Caries; Dental Enamel Hypoplasia; Diet; DMF Index; Female; Humans; Hydrogen-Ion Concentration; Male; Oral Hygiene; Saliva; Secretory Rate; Tobramycin; Toothbrushing	2014
Practice guidelines, clinical trials, and unexpected results in cystic fibrosis. Annals of the American Thoracic Society, 2014, Volume: 11, Issue:3 Topics: Anti-Bacterial Agents; Azithromycin; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2014
A survey of extended-interval aminoglycoside dosing practices in United States adult cystic fibrosis programs. Respiratory care, 2014, Volume: 59, Issue:9 Topics: Adult; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Cystic Fibrosis; Disease Progression; Drug Administration Schedule; Drug Monitoring; Gentamicins; Health Care Surveys; Humans; Middle Aged; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tobramycin; United States	2014
Skin contamination leading to falsely elevated fingerprick tobramycin levels in a patient taking dry powder inhaled tobramycin. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:6 Topics: Administration, Cutaneous; Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Diagnostic Errors; Dry Powder Inhalers; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Skin; Tobramycin; Young Adult	2014
Inhaled versus nebulised tobramycin: a real world comparison in adult cystic fibrosis (CF). Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Cohort Studies; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Medication Adherence; Middle Aged; Nebulizers and Vaporizers; Patient Satisfaction; Pseudomonas aeruginosa; Pseudomonas Infections; Surveys and Questionnaires; Tobramycin; Treatment Outcome; Young Adult	2014
Tobramycin inhalation solution (Bethkis) for cystic fibrosis. The Medical letter on drugs and therapeutics, 2014, Jun-23, Volume: 56, Issue:1445 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Drug Approval; Drug Interactions; Forced Expiratory Volume; Humans; Pseudomonas Infections; Tobramycin	2014
Systemic absorption of nasally administered tobramycin and colistin in patients with cystic fibrosis. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:11 Topics: Absorption, Physiological; Administration, Intranasal; Adult; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Female; Humans; Male; Nasal Mucosa; Tobramycin; Young Adult	2014
Linezolid-resistant Staphylococcus aureus strain 1128105, the first known clinical isolate possessing the cfr multidrug resistance gene. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:11 Topics: Acetamides; Adult; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Ceftazidime; Cystic Fibrosis; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Genes, MDR; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Sequence Data; Multilocus Sequence Typing; Oxazolidinones; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; RNA, Ribosomal, 23S; Sequence Analysis, DNA; Staphylococcal Infections; Tobramycin	2014
Enhanced in vitro formation and antibiotic resistance of nonattached Pseudomonas aeruginosa aggregates through incorporation of neutrophil products. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:11 Topics: Anti-Bacterial Agents; Azithromycin; Biofilms; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Humans; Metalloproteases; Microbial Sensitivity Tests; Neutrophils; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Sputum; Tobramycin; Virulence Factors	2014
Nasal saline as a placebo in a rhinosinusitis study. Drug design, development and therapy, 2014, Volume: 8 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Tobramycin	2014
Authors’ reply. Drug design, development and therapy, 2014, Volume: 8 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Tobramycin	2014
In vitro efficacy of high-dose tobramycin against Burkholderia cepacia complex and Stenotrophomonas maltophilia isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1 Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Stenotrophomonas maltophilia; Tobramycin	2015
Comparing dosage adjustment methods for once-daily tobramycin in paediatric and adolescent patients with cystic fibrosis. Clinical pharmacokinetics, 2015, Volume: 54, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Bayes Theorem; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Linear Models; Male; Nomograms; Retrospective Studies; Tobramycin	2015
Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: formulation, characterisation and functionalisation with dornase alfa (DNase). Journal of controlled release : official journal of the Controlled Release Society, 2015, Jan-28, Volume: 198 Topics: Adult; Alginates; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Chitosan; Cystic Fibrosis; Deoxyribonuclease I; DNA; Glucuronic Acid; Hexuronic Acids; Humans; Microbial Sensitivity Tests; Nanoparticles; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sputum; Tobramycin; Treatment Outcome	2015
Association between the introduction of a new cystic fibrosis inhaled antibiotic class and change in prevalence of patients receiving multiple inhaled antibiotic classes. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2015, Volume: 14, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Aztreonam; Child; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin; Treatment Outcome; Young Adult	2015
Real-time monitoring of hydrogen cyanide (HCN) and ammonia (NH₃) emitted by Pseudomonas aeruginosa. Journal of breath research, 2015, Jan-29, Volume: 9, Issue:2 Topics: Ammonia; Colony Count, Microbial; Cystic Fibrosis; Humans; Hydrogen Cyanide; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	2015
A demonstration of the susceptibility of clinical isolates obtained from cystic fibrosis patients to manuka honey. Archives of microbiology, 2015, Volume: 197, Issue:4 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Burkholderia; Burkholderia Infections; Colistin; Cystic Fibrosis; Honey; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2015
Geographic variations in cystic fibrosis: An analysis of the U.S. CF Foundation Registry. Pediatric pulmonology, 2015, Volume: 50, Issue:8 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Body Mass Index; Child; Child, Preschool; Cystic Fibrosis; Deoxyribonuclease I; Female; Forced Expiratory Volume; Humans; Infant; Infant, Newborn; Male; Medicaid; Middle Aged; Racial Groups; Recombinant Proteins; Registries; Tobramycin; United States; Young Adult	2015
Novel inhaled combined antibiotic formulations in the treatment of Pseudomonas aeruginosa airways infections in cystic fibrosis. Expert review of anti-infective therapy, 2015, Volume: 13, Issue:7 Topics: Administration, Inhalation; Anti-Bacterial Agents; Clinical Trials as Topic; Cystic Fibrosis; Drug Combinations; Fosfomycin; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2015
In Vivo Efficacy of Antimicrobials against Biofilm-Producing Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Animals; Anti-Infective Agents; Biofilms; Cell Line, Tumor; Colistin; Cystic Fibrosis; Disease Models, Animal; Female; Lung Diseases; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2015
TOBI Podhaler for cystic fibrosis patients with Pseudomonas aeruginosa. The Nurse practitioner, 2015, Jul-15, Volume: 40, Issue:7 Topics: Administration, Inhalation; Anti-Bacterial Agents; Clinical Trials as Topic; Cystic Fibrosis; Dry Powder Inhalers; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2015
d-Methionine reduces tobramycin-induced ototoxicity without antimicrobial interference in animal models. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:4 Topics: Animals; Anti-Infective Agents; Cystic Fibrosis; Drug Monitoring; Ear Diseases; Escherichia coli; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hair Cells, Auditory, Outer; Methionine; Mice; Protective Agents; Tobramycin	2016
Pharmacokinetics of once and twice daily dosing of intravenous tobramycin in paediatric patients with cystic fibrosis. Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Drug Administration Schedule; Female; Humans; Infant; Lung Diseases; Male; Retrospective Studies; Tobramycin	2016
Tobramycin-Treated Pseudomonas aeruginosa PA14 Enhances Streptococcus constellatus 7155 Biofilm Formation in a Cystic Fibrosis Model System. Journal of bacteriology, 2016, 01-15, Volume: 198, Issue:2 Topics: Anti-Bacterial Agents; Bacteriological Techniques; Biofilms; Coculture Techniques; Cystic Fibrosis; Glycolipids; Humans; Pseudomonas aeruginosa; Streptococcus constellatus; Tobramycin	2016
Chronic infection phenotypes of Pseudomonas aeruginosa are associated with failure of eradication in children with cystic fibrosis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2016, Volume: 35, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; Canada; Child; Child, Preschool; Cross-Sectional Studies; Cystic Fibrosis; Drug Resistance, Bacterial; Female; Gene Deletion; Humans; Locomotion; Male; Microbial Sensitivity Tests; Phenotype; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Tobramycin; Treatment Failure	2016
Activity of Tobramycin against Cystic Fibrosis Isolates of Burkholderia cepacia Complex Grown as Biofilms. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Anti-Bacterial Agents; Biofilms; Burkholderia; Burkholderia cepacia complex; Child; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Microscopy, Confocal; Species Specificity; Sputum; Tobramycin	2016
Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas aeruginosa in a Cystic Fibrosis Model System of Biofilm Formation. PloS one, 2015, Volume: 10, Issue:10 Topics: Biofilms; Cystic Fibrosis; Humans; Lung; Mannitol; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2015
Effect of High-Dose Antimicrobials on Biofilm Growth of Achromobacter Species Isolated from Cystic Fibrosis Patients. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Achromobacter; Amikacin; Anti-Bacterial Agents; Aztreonam; Biofilms; Colistin; Cystic Fibrosis; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Plankton; Tobramycin	2016
Pulmonary delivery of tobramycin-loaded nanostructured lipid carriers for Pseudomonas aeruginosa infections associated with cystic fibrosis. International journal of pharmaceutics, 2016, Feb-10, Volume: 498, Issue:1-2 Topics: Administration, Inhalation; Animals; Cystic Fibrosis; Drug Carriers; Drug Delivery Systems; Female; Humans; Lipids; Mice; Mice, Inbred BALB C; Nanostructures; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2016
Impairment of Pseudomonas aeruginosa Biofilm Resistance to Antibiotics by Combining the Drugs with a New Quorum-Sensing Inhibitor. Antimicrobial agents and chemotherapy, 2015, Dec-28, Volume: 60, Issue:3 Topics: Amides; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Synergism; Drug Therapy, Combination; Humans; Lung; Microscopy, Confocal; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrimidines; Quorum Sensing; Respiratory Tract Infections; Tobramycin	2015
Tolerability and Pharmacokinetic Evaluation of Inhaled Dry Powder Tobramycin Free Base in Non-Cystic Fibrosis Bronchiectasis Patients. PloS one, 2016, Volume: 11, Issue:3 Topics: Administration, Inhalation; Adult; Aged; Bronchiectasis; Cystic Fibrosis; Dose-Response Relationship, Drug; Dry Powder Inhalers; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Powders; Tobramycin	2016
Two case reports of the successful eradication of new isolates of Burkholderia cepacia complex in children with cystic fibrosis. BMC pharmacology & toxicology, 2016, Mar-28, Volume: 17 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Burkholderia cepacia complex; Burkholderia Infections; Ceftazidime; Child; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; England; Female; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Penicillins; Tobramycin; Treatment Outcome	2016
The development of a single-use, capsule-free multi-breath tobramycin dry powder inhaler for the treatment of cystic fibrosis. International journal of pharmaceutics, 2016, Dec-05, Volume: 514, Issue:2 Topics: Administration, Inhalation; Aerosols; Chemical Phenomena; Cystic Fibrosis; Drug Compounding; Dry Powder Inhalers; Particle Size; Powders; Tobramycin	2016
Evaluation of a Once/Day Tobramycin Regimen to Achieve Target Concentrations in Adult Patients with Cystic Fibrosis. Pharmacotherapy, 2016, Volume: 36, Issue:6 Topics: Adult; Anti-Bacterial Agents; Body Mass Index; Creatinine; Cystic Fibrosis; Female; Georgia; Humans; Kidney Diseases; Male; Retrospective Studies; Tobramycin; Young Adult	2016
Off-label use of inhaled tobramycin in Ontario, Canada. Thorax, 2016, Volume: 71, Issue:9 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Drug Utilization; Humans; Off-Label Use; Ontario; Pulmonary Disease, Chronic Obstructive; Tobramycin	2016
Activity of Cysteamine against the Cystic Fibrosis Pathogen Burkholderia cepacia Complex. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:10 Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia complex; Cysteamine; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Tobramycin	2016
Sequential Inhalational Tobramycin-Colistin-Combination in CF-Patients with Chronic P. Aeruginosa Colonization - an Observational Study. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Colistin; Cystic Fibrosis; Drug Administration Schedule; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2016
Urinary kidney injury biomarkers and tobramycin clearance among children and young adults with cystic fibrosis: a population pharmacokinetic analysis. The Journal of antimicrobial chemotherapy, 2017, Volume: 72, Issue:1 Topics: Administration, Intravenous; Adolescent; Anti-Bacterial Agents; Biomarkers; Bronchopneumonia; Child; Creatinine; Cystic Fibrosis; Drug Monitoring; Female; Hepatitis A Virus Cellular Receptor 1; Hospitals, Pediatric; Humans; Lipocalin-2; Male; Metabolic Clearance Rate; Ohio; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Retinol-Binding Proteins; Tobramycin; Young Adult	2017
Improving inhaled antibiotic treatment - Practice defeats the proof. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:6 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Pseudomonas Infections; Tobramycin	2016
Polyanion-tobramycin nanocomplexes into functional microparticles for the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. Nanomedicine (London, England), 2017, Volume: 12, Issue:1 Topics: Anti-Bacterial Agents; Cell Line; Cystic Fibrosis; Drug Carriers; Drug Liberation; Epithelial Cells; Humans; Mannitol; Mucus; Nanocomposites; Polyelectrolytes; Polymers; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2017
Antimicrobial susceptibility of Pseudomonas aeruginosa before and after initiation of inhaled tobramycin in Bulgaria. Journal of infection in developing countries, 2016, Nov-24, Volume: 10, Issue:11 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Bulgaria; Child; Child, Preschool; Cystic Fibrosis; Disk Diffusion Antimicrobial Tests; Female; Humans; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin; Young Adult	2016
The cumulative effects of intravenous antibiotic treatments on hearing in patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:3 Topics: Adolescent; Adult; Age Factors; Amikacin; Anti-Bacterial Agents; Audiometry, Pure-Tone; Bacterial Infections; Cystic Fibrosis; Female; Hearing Loss; Humans; Male; Middle Aged; Patient Outcome Assessment; Sex Factors; Time; Tobramycin; United States; Vancomycin	2017
In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia. FEMS microbiology letters, 2008, Volume: 285, Issue:1 Topics: Amiloride; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Interactions; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Membrane Transport Modulators; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2008
Vestibulotoxicity as a consequence of systemically administered tobramycin in cystic fibrosis patients. Acta oto-laryngologica, 2009, Volume: 129, Issue:1 Topics: Adult; Anti-Bacterial Agents; Caloric Tests; Cohort Studies; Cystic Fibrosis; Dizziness; Dose-Response Relationship, Drug; Electronystagmography; Female; Humans; Male; Meniere Disease; Middle Aged; Pneumonia, Bacterial; Prospective Studies; Pseudomonas Infections; Tobramycin; Vestibular Diseases; Vestibule, Labyrinth	2009
Shifting patterns of inhaled antibiotic use in cystic fibrosis. Pediatric pulmonology, 2008, Volume: 43, Issue:9 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Colistin; Cystic Fibrosis; Drug Utilization; Female; Humans; Male; Respiratory Tract Infections; Tobramycin	2008
Effect of antibiotic co-administration on young and mature biofilms of cystic fibrosis clinical isolates: the importance of the biofilm model. International journal of antimicrobial agents, 2009, Volume: 33, Issue:1 Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia; Clarithromycin; Cystic Fibrosis; Drug Combinations; Drug Synergism; Humans; Microbial Sensitivity Tests; Models, Biological; Pseudomonas aeruginosa; Staphylococcus aureus; Time Factors; Tobramycin	2009
Physicochemical compatibility of mixtures of dornase alfa and tobramycin containing nebulizer solutions. Pediatric pulmonology, 2009, Volume: 44, Issue:2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Chemical Phenomena; Cystic Fibrosis; Deoxyribonuclease I; Drug Combinations; Drug Incompatibility; Humans; Nebulizers and Vaporizers; Pharmaceutical Solutions; Tobramycin	2009
Cationic amphiphiles increase activity of aminoglycoside antibiotic tobramycin in the presence of airway polyelectrolytes. Journal of the American Chemical Society, 2009, Jan-21, Volume: 131, Issue:2 Topics: Anti-Bacterial Agents; Cations; Cystic Fibrosis; DNA; DNA Adducts; Drug Synergism; Electrolytes; Lipid Metabolism; Lipids; Microbial Sensitivity Tests; Microscopy, Confocal; Scattering, Small Angle; Tobramycin; X-Ray Diffraction	2009
Tobramycin and FDA-approved iron chelators eliminate Pseudomonas aeruginosa biofilms on cystic fibrosis cells. American journal of respiratory cell and molecular biology, 2009, Volume: 41, Issue:3 Topics: Anti-Bacterial Agents; Benzoates; Biofilms; Cells, Cultured; Conalbumin; Cystic Fibrosis; Deferasirox; Deferoxamine; Epithelial Cells; Humans; Iron Chelating Agents; Pseudomonas Infections; Tobramycin; Triazoles; United States; United States Food and Drug Administration	2009
Pulmonary deposition of inhaled tobramycin prior to and after respiratory therapy and use of inhaled albuterol in cystic fibrosis patients colonized with Pseudomonas aeruginosa. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2009, Volume: 35, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Anti-Bacterial Agents; Bronchodilator Agents; Child; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epidemiologic Methods; Female; Genotype; Humans; Lung; Male; Mutation; Pseudomonas Infections; Radiopharmaceuticals; Respiratory Therapy; Technetium; Tobramycin; Young Adult	2009
Parenteral administration of tobramycin for pulmonary exacerbations in cystic fibrosis patients: toxicity, serum levels and efficacy. Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cochlea; Cystic Fibrosis; Female; Gram-Negative Bacterial Infections; Hearing Loss; Humans; Infusions, Parenteral; Kidney; Male; Tobramycin	2009
A survey of once-daily dosage tobramycin therapy in patients with cystic fibrosis. Pediatric pulmonology, 2009, Volume: 44, Issue:4 Topics: Adult; Anti-Bacterial Agents; Child; Cross-Sectional Studies; Cystic Fibrosis; Drug Administration Schedule; Drug Monitoring; Drug Utilization; Health Care Surveys; Hospitals; Humans; Pediatrics; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; United States	2009
Implementation of European standards of care for cystic fibrosis--control and treatment of infection. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2009, Volume: 8, Issue:3 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Bacterial Infections; Burkholderia cepacia; Burkholderia Infections; Child; Child, Preschool; Ciprofloxacin; Colistin; Cystic Fibrosis; Europe; Guideline Adherence; Humans; Infection Control; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Surveys and Questionnaires; Tobramycin; Young Adult	2009
Successful treatment of cepacia syndrome. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2009, Volume: 8, Issue:4 Topics: Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Child; Cystic Fibrosis; Deoxyribonuclease I; Drug Therapy, Combination; Female; Humans; Radiography; Tobramycin	2009
The costs of treatment of early and chronic Pseudomonas aeruginosa infection in cystic fibrosis patients. Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:2 Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Child, Preschool; Chronic Disease; Ciprofloxacin; Clavulanic Acids; Colistin; Cost of Illness; Cystic Fibrosis; Humans; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Thienamycins; Ticarcillin; Tobramycin	2009
Tobramycin-induced aquagenic wrinkling of the palms in a patient with cystic fibrosis. Clinical and experimental dermatology, 2009, Volume: 34, Issue:5 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Drug Eruptions; Female; Hand Dermatoses; Humans; Skin Aging; Tobramycin; Water	2009
Changes in performance of the Pari eFlow rapid and Pari LC Plus during 6 months use by CF patients. Journal of aerosol medicine and pulmonary drug delivery, 2009, Volume: 22, Issue:3 Topics: Adult; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Medication Adherence; Nebulizers and Vaporizers; Particle Size; Time Factors; Tobramycin	2009
Activity and interactions of liposomal antibiotics in presence of polyanions and sputum of patients with cystic fibrosis. PloS one, 2009, May-28, Volume: 4, Issue:5 Topics: Actins; Animals; Anti-Bacterial Agents; Cystic Fibrosis; DNA; Humans; Lipopolysaccharides; Liposomes; Microbial Sensitivity Tests; Polyelectrolytes; Polymers; Pseudomonas aeruginosa; Rabbits; Sputum; Teichoic Acids; Tobramycin	2009
No hearing loss after repeated courses of tobramycin in cystic fibrosis patients. Acta oto-laryngologica, 2010, Volume: 130, Issue:2 Topics: Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Cystic Fibrosis; Drug Administration Schedule; Female; Follow-Up Studies; Hearing; Humans; Male; Retrospective Studies; Tobramycin; Treatment Outcome	2010
Evaluation of long-term co-administration of tobramycin and clarithromycin in a mature biofilm model of cystic fibrosis clinical isolates of Pseudomonas aeruginosa. International journal of antimicrobial agents, 2009, Volume: 34, Issue:4 Topics: Anti-Bacterial Agents; Biofilms; Clarithromycin; Colony Count, Microbial; Cystic Fibrosis; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Genotype; Humans; Models, Biological; Phenotype; Pseudomonas aeruginosa; Sputum; Time Factors; Tobramycin; Treatment Outcome	2009
[Ochrobactrum anthropi bacteremia in a child with cystic fibrosis]. Enfermedades infecciosas y microbiologia clinica, 2010, Volume: 28, Issue:2 Topics: Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Child; Cholecystitis; Cystic Fibrosis; Disease Susceptibility; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Male; Ochrobactrum anthropi; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	2010
Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy, 2009, Volume: 64, Issue:6 Topics: Animals; Anti-Bacterial Agents; Chemokine CXCL2; Colony Count, Microbial; Cystic Fibrosis; Disease Models, Animal; Female; Granulocyte Colony-Stimulating Factor; Humans; Lung; Mice; Mice, Inbred BALB C; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Severity of Illness Index; Time Factors; Tobramycin	2009
What is the best method for measuring renal function in adults and children with cystic fibrosis? Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2010, Volume: 9, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Creatinine; Cystatin C; Cystic Fibrosis; Data Interpretation, Statistical; Female; Glomerular Filtration Rate; Humans; Infections; Injections, Intravenous; Kidney Function Tests; Lung Diseases; Male; Middle Aged; Radiopharmaceuticals; Sensitivity and Specificity; Technetium Tc 99m Pentetate; Tobramycin; Young Adult	2010
Direct comparison of in vitro susceptibility of wildtype clinical Pseudomonas aeruginosa isolated from adult patients with cystic fibrosis (CF) to TOBI and BRAMITOB (tobramycin inhalation solutions). Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2010, Volume: 9, Issue:3 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Young Adult	2010
Exploratory study of the prevalence and clinical significance of tobramycin-mediated biofilm induction in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7 Topics: Adolescent; Biofilms; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	2010
Serum tobramycin levels following delivery of tobramycin (Tobi) via eFlow advanced nebuliser in children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2010, Volume: 9, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Drug Monitoring; Female; Humans; Male; Nebulizers and Vaporizers; Pilot Projects; Tobramycin	2010
Pulmonary exacerbations in cystic fibrosis with negative bacterial cultures. Pediatric pulmonology, 2010, Volume: 45, Issue:6 Topics: Adolescent; Anti-Bacterial Agents; Azithromycin; Bronchoalveolar Lavage Fluid; Child; Cystic Fibrosis; Disease Progression; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Sputum; Tobramycin; Young Adult	2010
Minimizing the toxicity of aminoglycosides in cystic fibrosis. Journal of the Royal Society of Medicine, 2010, Volume: 103 Suppl 1 Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; DNA, Mitochondrial; Drug Administration Schedule; Genetic Predisposition to Disease; Gentamicins; Hearing Loss, Sensorineural; Humans; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Renal Insufficiency; Tobramycin	2010
In vitro inhibition of neutrophil elastase activity by inhaled anti-Pseudomonas antibiotics used in cystic fibrosis patients. Mediators of inflammation, 2010, Volume: 2010 Topics: Administration, Inhalation; Albumins; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Humans; Leukocyte Elastase; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas Infections; Tobramycin	2010
Budget impact model of tobramycin inhalation solution for treatment of Pseudomonas aeruginosa in cystic fibrosis patients. Journal of medical economics, 2010, Volume: 13, Issue:3 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Disease Progression; Female; Humans; Male; Managed Care Programs; Models, Economic; Patient Admission; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; United States	2010
Stationary biofilm growth normalizes mutation frequencies and mutant prevention concentrations in Pseudomonas aeruginosa from cystic fibrosis patients. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2011, Volume: 17, Issue:5 Topics: Anti-Bacterial Agents; Biofilms; Ceftazidime; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Bacterial; Genetic Variation; Humans; Imipenem; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory System; Tobramycin	2011
Resistance to tobramycin and colistin in isolates of Pseudomonas aeruginosa from chronically colonized patients with cystic fibrosis under antimicrobial treatment. Scandinavian journal of infectious diseases, 2010, Volume: 42, Issue:11-12 Topics: Adult; Anti-Bacterial Agents; Bacterial Typing Techniques; Chronic Disease; Cluster Analysis; Colistin; Cystic Fibrosis; DNA Fingerprinting; Drug Resistance, Bacterial; Female; Genotype; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2010
Aquagenic wrinkling of the palms in an adult cystic fibrosis population. Dermatology (Basel, Switzerland), 2010, Volume: 221, Issue:4 Topics: Adolescent; Adult; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Incidence; Male; Middle Aged; Northern Ireland; Skin Aging; Tobramycin; Treatment Outcome; Water; Young Adult	2010
Improving evidence-based care in cystic fibrosis through quality improvement. Archives of pediatrics & adolescent medicine, 2010, Volume: 164, Issue:10 Topics: Administration, Inhalation; Administration, Oral; Ambulatory Care; Anti-Bacterial Agents; Azithromycin; Child; Cystic Fibrosis; Deoxyribonuclease I; Evidence-Based Medicine; Guideline Adherence; Hospitals, Pediatric; Humans; Ohio; Practice Patterns, Physicians'; Quality of Health Care; Tobramycin	2010
Disposable versus reusable jet nebulizers for cystic fibrosis treatment with tobramycin. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:2 Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Cystic Fibrosis; Data Collection; Equipment Reuse; Humans; Lung; Masks; Nebulizers and Vaporizers; Papio; Particle Size; Pneumonia, Bacterial; Tobramycin	2011
Development of the first inhaled antibiotic for the treatment of cystic fibrosis. Science translational medicine, 2010, Dec-22, Volume: 2, Issue:63 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Tobramycin; United States; United States Food and Drug Administration	2010
Adherence with tobramycin inhaled solution and health care utilization. BMC pulmonary medicine, 2011, Jan-20, Volume: 11 Topics: Adolescent; Adult; Child; Cystic Fibrosis; Female; Health Services; Hospitalization; Humans; Male; Medication Adherence; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Young Adult	2011
Outpatient treatment of Pseudomonas aeruginosa bronchial colonization with long-term inhaled colistin, tobramycin, or both in adults without cystic fibrosis. Pharmacotherapy, 2011, Volume: 31, Issue:2 Topics: Administration, Inhalation; Ambulatory Care; Anti-Bacterial Agents; Bronchitis, Chronic; Colistin; Cystic Fibrosis; Data Interpretation, Statistical; Drug Therapy, Combination; Female; Hospitalization; Humans; Male; Middle Aged; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2011
Antimicrobial activity of tobramycin against respiratory cystic fibrosis Pseudomonas aeruginosa isolates from Bulgaria. Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Bulgaria; Child; Cystic Fibrosis; Female; Humans; Male; Microbial Sensitivity Tests; Phenotype; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory System; Sputum; Tobramycin; Young Adult	2010
Economic effects of an eradication protocol for first appearance of Pseudomonas aeruginosa in cystic fibrosis patients: 1995 vs. 2009. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:3 Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Burkholderia cepacia complex; Child; Child, Preschool; Ciprofloxacin; Cohort Studies; Colistin; Cystic Fibrosis; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Health Care Costs; Health Resources; Humans; Infant; Injections, Intravenous; Nebulizers and Vaporizers; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome	2011
Epidemiology of borderline oxacillin-resistant Staphylococcus aureus in pediatric cystic fibrosis. Pediatric pulmonology, 2011, Volume: 46, Issue:5 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; Cephalexin; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Infant; Male; Methicillin; Oxacillin; Penicillin Resistance; Penicillin-Binding Proteins; Retrospective Studies; Staphylococcal Infections; Staphylococcus aureus; Tobramycin	2011
In vitro activity of fusidic acid (CEM-102, sodium fusidate) against Staphylococcus aureus isolates from cystic fibrosis patients and its effect on the activities of tobramycin and amikacin against Pseudomonas aeruginosa and Burkholderia cepacia. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Amikacin; Burkholderia cepacia; Cystic Fibrosis; Drug Synergism; Fusidic Acid; Humans; Pseudomonas aeruginosa; Staphylococcus aureus; Tobramycin	2011
Longitudinal association between medication adherence and lung health in people with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Azithromycin; Child; Cystic Fibrosis; Deoxyribonuclease I; Drug Prescriptions; Female; Forced Expiratory Volume; Humans; Infusions, Intravenous; Longitudinal Studies; Male; Medication Adherence; Outcome Assessment, Health Care; Pharmacy; Retrospective Studies; Tobramycin; Young Adult	2011
Twice vs three times daily antibiotics in the treatment of pulmonary exacerbations of cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011, Volume: 10, Issue:5 Topics: Ceftazidime; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2011
Tobramycin pharmacokinetics in patients with cystic fibrosis before and after bilateral lung transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2011, Volume: 13, Issue:6 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Hospitals, Teaching; Humans; Lung Transplantation; Male; Retrospective Studies; Tobramycin	2011
Improved outcomes of patients with end-stage cystic fibrosis requiring invasive mechanical ventilation for acute respiratory failure. Lung, 2011, Volume: 189, Issue:5 Topics: Acute Disease; Adult; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Female; Humans; Male; Malnutrition; Respiration, Artificial; Respiratory Function Tests; Respiratory Insufficiency; Retrospective Studies; Severity of Illness Index; Tobramycin; Treatment Outcome; Young Adult	2011
Reduced mortality in cystic fibrosis patients treated with tobramycin inhalation solution. Pediatric pulmonology, 2012, Volume: 47, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Deoxyribonuclease I; Female; Humans; Longitudinal Studies; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2012
Antibacterial and anti-biofilm effects of cathelicidin peptides against pathogens isolated from cystic fibrosis patients. Peptides, 2011, Volume: 32, Issue:9 Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Biofilms; Blood Proteins; Cathelicidins; Cattle; Cystic Fibrosis; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Molecular Sequence Data; Proteins; Pseudomonas aeruginosa; Sheep; Staphylococcal Infections; Staphylococcus aureus; Stenotrophomonas maltophilia; Tobramycin	2011
What have we learned about early treatment of Pseudomonas aeruginosa infection in infants and children with cystic fibrosis? Archives of pediatrics & adolescent medicine, 2011, Volume: 165, Issue:9 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2011
Economic impact of tobramycin in patients with cystic fibrosis in a managed care population. Journal of medical economics, 2011, Volume: 14, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Costs and Cost Analysis; Cystic Fibrosis; Female; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Managed Care Programs; Middle Aged; Pseudomonas Infections; Retrospective Studies; Tobramycin; Young Adult	2011
Cystic fibrosis upper airways primary colonization with Pseudomonas aeruginosa: eradicated by sinonasal antibiotic inhalation. American journal of respiratory and critical care medicine, 2011, Nov-01, Volume: 184, Issue:9 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Cystic Fibrosis; Follow-Up Studies; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Rhinitis; Sinusitis; Tobramycin; Treatment Outcome	2011
Antimicrobial activity of fosfomycin and tobramycin in combination against cystic fibrosis pathogens under aerobic and anaerobic conditions. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012, Volume: 11, Issue:3 Topics: Anti-Bacterial Agents; Biofilms; Colony Count, Microbial; Cystic Fibrosis; Drug Combinations; Fosfomycin; Humans; Lung; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Tobramycin	2012
Activity of pyocin S2 against Pseudomonas aeruginosa biofilms. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:3 Topics: Animals; Anti-Bacterial Agents; Aztreonam; Biofilms; Child; Cystic Fibrosis; Humans; Larva; Lung; Microscopy, Electron, Scanning; Moths; Pseudomonas aeruginosa; Pyocins; Sputum; Tobramycin	2012
Therapeutic approaches to chronic cystic fibrosis respiratory infections with available, emerging aerosolized antibiotics. Respiratory medicine, 2011, Volume: 105 Suppl 2 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2011
In vitro activities of the novel ceragenin CSA-13, alone or in combination with colistin, tobramycin, and ciprofloxacin, against Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. Chemotherapy, 2011, Volume: 57, Issue:6 Topics: Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Steroids; Tobramycin	2011
The Case ∣ Metabolic alkalosis in a patient with cystic fibrosis. Kidney international, 2012, Volume: 81, Issue:4 Topics: Adult; Alkalosis; Aminoglycosides; Anti-Bacterial Agents; Bartter Syndrome; Cystic Fibrosis; Female; Humans; Tobramycin; Young Adult	2012
Long-term effect of chronic intravenous and inhaled nephrotoxic antibiotic treatment on the renal function of patients with cystic fibrosis. Hemodialysis international. International Symposium on Home Hemodialysis, 2012, Volume: 16, Issue:3 Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Female; Gentamicins; Humans; Infusions, Intravenous; Kidney; Male; Retrospective Studies; Time; Tobramycin	2012
Adherence to the 2007 cystic fibrosis pulmonary guidelines: a national survey of CF care centers. Pediatric pulmonology, 2012, Volume: 47, Issue:5 Topics: Adolescent; Adult; Anti-Bacterial Agents; Attitude of Health Personnel; Child; Cystic Fibrosis; Deoxyribonuclease I; Female; Guideline Adherence; Health Care Surveys; Humans; Macrolides; Male; Middle Aged; Practice Guidelines as Topic; Tobramycin; Treatment Outcome; Young Adult	2012
Invasive pneumonia and septic shock in infants as a presentation of cystic fibrosis with vitamin-deficiency. Pediatric pulmonology, 2012, Volume: 47, Issue:7 Topics: Ampicillin; Anti-Bacterial Agents; Avitaminosis; Ceftazidime; Cystic Fibrosis; Drug Therapy, Combination; Humans; Infant; Male; Pneumonia, Bacterial; Respiration, Artificial; Respiratory Insufficiency; Shock, Septic; Tobramycin; Treatment Outcome	2012
Use of artificial sputum medium to test antibiotic efficacy against Pseudomonas aeruginosa in conditions more relevant to the cystic fibrosis lung. Journal of visualized experiments : JoVE, 2012, Jun-05, Issue:64 Topics: Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Humans; Lung; Microbial Sensitivity Tests; Oxazines; Pseudomonas aeruginosa; Sputum; Tobramycin; Xanthenes	2012
Prevalence of streptococci and increased polymicrobial diversity associated with cystic fibrosis patient stability. Journal of bacteriology, 2012, Volume: 194, Issue:17 Topics: Adult; Anti-Bacterial Agents; Base Sequence; Cystic Fibrosis; DNA, Bacterial; Female; Humans; Lung; Male; Metagenome; Middle Aged; Pseudomonas aeruginosa; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sputum; Streptococcus; Tobramycin; Young Adult	2012
In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells. The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:11 Topics: Anti-Bacterial Agents; Aztreonam; Biofilms; Cystic Fibrosis; Epithelial Cells; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors; Tobramycin	2012
Aztreonam for inhalation solution, challenges to drug approval and integration into CF care. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:2 Topics: Anti-Bacterial Agents; Aztreonam; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Tobramycin	2013
A pulmonary exacerbation risk score among cystic fibrosis patients not receiving recommended care. Pediatric pulmonology, 2013, Volume: 48, Issue:10 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Deoxyribonuclease I; Female; Humans; Logistic Models; Lung; Male; Recombinant Proteins; Risk Factors; Tobramycin; Young Adult	2013
Timing of inhaled tobramycin affects assessment of intravenous tobramycin pharmacokinetic monitoring. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Drug Monitoring; Female; Humans; Male; Tobramycin; Veins; Young Adult	2013
[Effects of Imipenem, Tobramycin and Curcumin on Biofilm Formation of Pseudomonas aeruginosa Strains]. Mikrobiyoloji bulteni, 2013, Volume: 47, Issue:1 Topics: Anti-Bacterial Agents; Biofilms; Curcumin; Cystic Fibrosis; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2013
Colistin stimulates the activity of neutrophil elastase and Pseudomonas aeruginosa elastase. The European respiratory journal, 2002, Volume: 19, Issue:6 Topics: Adolescent; Adult; alpha 1-Antitrypsin; Amino Acid Chloromethyl Ketones; Anti-Bacterial Agents; Anticoagulants; Bacterial Proteins; Ceftazidime; Child; Colistin; Cystic Fibrosis; Enzyme Activation; Erythromycin; Female; Gentamicins; Heparin; Humans; In Vitro Techniques; Leukocyte Elastase; Male; Metalloendopeptidases; Respiratory Tract Infections; Serine Proteinase Inhibitors; Sputum; Tobramycin	2002
Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene. Journal of molecular medicine (Berlin, Germany), 2002, Volume: 80, Issue:9 Topics: Action Potentials; Animals; Anti-Bacterial Agents; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Expression; Gentamicins; Heterozygote; Humans; Intestinal Mucosa; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Promoter Regions, Genetic; RNA, Messenger; Suppression, Genetic; Tobramycin; Transgenes	2002
Distribution and elimination of tobramycin administered in single or multiple daily doses in adult patients with cystic fibrosis. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:4 Topics: Adult; Cross-Over Studies; Cystic Fibrosis; Drug Administration Schedule; Female; Humans; Male; Models, Biological; Patients; Prospective Studies; Statistics, Nonparametric; Tissue Distribution; Tobramycin	2002
Acute renal failure in cystic fibrosis: association with inhaled tobramycin therapy. Pediatric pulmonology, 2002, Volume: 34, Issue:5 Topics: Acute Kidney Injury; Administration, Inhalation; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	2002
Tobramycin for nebulisation: new formulation. A high price for a small improvement in formulation. Prescrire international, 2002, Volume: 11, Issue:62 Topics: Administration, Inhalation; Anti-Bacterial Agents; Clinical Trials as Topic; Cystic Fibrosis; Deafness; Drug Approval; Drug Evaluation; European Union; Humans; Pneumonia; Pseudomonas aeruginosa; Tinnitus; Tobramycin; Voice Disorders	2002
Mortality of cystic fibrosis patients treated with tobramycin solution for inhalation. Epidemiology (Cambridge, Mass.), 2003, Volume: 14, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Confounding Factors, Epidemiologic; Cystic Fibrosis; Humans; Infant; Infant, Newborn; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Registries; Risk Factors; Selection Bias; Tobramycin; United States	2003
So many drugs, so little time: the future challenge of cystic fibrosis care. Chest, 2003, Volume: 123, Issue:1 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Drug Delivery Systems; Forecasting; Humans; Time Factors; Tobramycin	2003
Susceptibility testing of Pseudomonas aeruginosa isolates and clinical response to parenteral antibiotic administration: lack of association in cystic fibrosis. Chest, 2003, Volume: 123, Issue:5 Topics: Anti-Bacterial Agents; Ceftazidime; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Injections, Intravenous; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Retrospective Studies; Sputum; Tobramycin	2003
Uptake of 18fluorodeoxyglucose in the cystic fibrosis lung: a measure of lung inflammation? The European respiratory journal, 2003, Volume: 21, Issue:5 Topics: Adult; Aged; Aminoglycosides; Cystic Fibrosis; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Middle Aged; Neutrophil Activation; Pneumonia; Radiopharmaceuticals; Sputum; Tobramycin; Tomography, Emission-Computed	2003
[Evaluation of a E-test method to detect bactericidy of beta lactam-aminoglycoside associations against Pseudomonas aeruginosa isolates from cystic fibrosis]. Pathologie-biologie, 2003, Volume: 51, Issue:3 Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2003
Survey of resistance of Pseudomonas aeruginosa from UK patients with cystic fibrosis to six commonly prescribed antimicrobial agents. Thorax, 2003, Volume: 58, Issue:9 Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Resistance, Bacterial; Gentamicins; Humans; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2003
Use of breakpoint combination sensitivity testing as a simple and convenient method to evaluate the combined effects of ceftazidime and tobramycin on Pseudomonas aeruginosa and Burkholderia cepacia complex isolates in vitro. Journal of microbiological methods, 2004, Volume: 57, Issue:1 Topics: Anti-Bacterial Agents; Burkholderia cepacia complex; Ceftazidime; Cystic Fibrosis; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	2004
Inhaled antibiotics. Pediatric pulmonology. Supplement, 2004, Volume: 26 Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Pseudomonas Infections; Tobramycin	2004
[Home intravenous antibiotic treatments in cystic fibrosis units of Madrid]. Medicina clinica, 2004, May-08, Volume: 122, Issue:17 Topics: Adolescent; Anti-Bacterial Agents; Ceftazidime; Child; Cystic Fibrosis; Female; Home Infusion Therapy; Humans; Infusions, Intravenous; Male; Respiratory Function Tests; Spain; Tobramycin; Treatment Outcome	2004
CF: an X-ray database to assess effect of aerosolized tobramycin. Pediatric pulmonology, 2004, Volume: 38, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infant; Male; Observer Variation; Radiography, Thoracic; Respiratory Function Tests; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Tobramycin; Treatment Outcome	2004
Falsely elevated serum tobramycin levels in a patient receiving nebulised tobramycin. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2002, Volume: 1, Issue:3 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Cystic Fibrosis; Drug Monitoring; False Positive Reactions; Female; Humans; Infusions, Intravenous; Nebulizers and Vaporizers; Respiratory Tract Infections; Tobramycin	2002
New clinical evidence from the European tobramycin trial in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2002, Volume: 1, Issue:Suppl 2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Europe; Humans; Lung Diseases; Nebulizers and Vaporizers; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Function Tests; Tobramycin; Treatment Outcome	2002
Insights into cystic fibrosis microbiology from the European tobramycin trial in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2002, Volume: 1, Issue:Suppl 2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Biofilms; Colistin; Cystic Fibrosis; Europe; Humans; Lung Diseases; Microbial Sensitivity Tests; Nebulizers and Vaporizers; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin	2002
Inhaled antibiotic therapy in evidence: what delivery device? Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2002, Volume: 1, Issue:Suppl 2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Cystic Fibrosis; Europe; Humans; Models, Theoretical; Nebulizers and Vaporizers; Tobramycin	2002
Economic evaluation of Tobramycin nebuliser solution in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2003, Volume: 2, Issue:3 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Hospital Costs; Humans; Male; Nebulizers and Vaporizers; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin	2003
Determination of tobramycin in saliva is not suitable for therapeutic drug monitoring of patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2004, Volume: 3, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Injections, Intravenous; Lung Diseases; Male; Nephelometry and Turbidimetry; Pseudomonas aeruginosa; Pseudomonas Infections; Saliva; Tobramycin	2004
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology (Reading, England), 2005, Volume: 151, Issue:Pt 2 Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Cystic Fibrosis; DNA-Binding Proteins; Female; Gene Expression Regulation, Bacterial; Humans; Hydrogen Peroxide; Mice; Mice, Inbred BALB C; Neutrophils; Pseudomonas aeruginosa; Pseudomonas Infections; Signal Transduction; Tobramycin; Trans-Activators; Virulence	2005
Development of a rapid colorimetric time-kill assay for determining the in vitro activity of ceftazidime and tobramycin in combination against Pseudomonas aeruginosa. Journal of microbiological methods, 2005, Volume: 61, Issue:2 Topics: Anti-Bacterial Agents; Ceftazidime; Colorimetry; Cystic Fibrosis; Drug Therapy, Combination; Formazans; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2005
Antibiotic tolerance induced by lactoferrin in clinical Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:4 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Lactoferrin; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2005
Inhaled tobramycin: not just for cystic fibrosis anymore? Chest, 2005, Volume: 127, Issue:4 Topics: Administration, Inhalation; Anti-Bacterial Agents; Bronchiectasis; Cystic Fibrosis; Humans; Lung Diseases; Pseudomonas Infections; Tobramycin	2005
Effect of intermittent inhaled tobramycin on sputum cytokine profiles in cystic fibrosis. The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:1 Topics: Administration, Inhalation; Adolescent; Adult; Cystic Fibrosis; Cytokines; Humans; Interleukin-6; Interleukin-8; Prospective Studies; Pseudomonas aeruginosa; Sputum; Tobramycin; Tumor Necrosis Factor-alpha	2005
Pharmacodynamics of tobramycin in patients with cystic fibrosis. Diagnostic microbiology and infectious disease, 2005, Volume: 52, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Child; Cystic Fibrosis; Forced Expiratory Volume; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin; Vital Capacity	2005
Measurement of tobramycin and gentamicin in saliva is not suitable for therapeutic drug monitoring of patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2005, Volume: 4, Issue:3 Topics: Adolescent; Anti-Bacterial Agents; Child; Cystic Fibrosis; Drug Monitoring; Gentamicins; Humans; Immunoassay; Saliva; Tobramycin	2005
Combination aerosol therapy to treat Burkholderia cepacia complex. The European respiratory journal, 2005, Volume: 26, Issue:2 Topics: Administration, Inhalation; Adult; Amiloride; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Nebulizers and Vaporizers; Sodium Channel Blockers; Tobramycin	2005
Breakpoints for predicting Pseudomonas aeruginosa susceptibility to inhaled tobramycin in cystic fibrosis patients: use of high-range Etest strips. Journal of clinical microbiology, 2005, Volume: 43, Issue:9 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Predictive Value of Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reagent Strips; Tobramycin	2005
Influence of gentamicin and tobramycin on binary biofilm formation by co-cultures of Burkholderia cepacia and Pseudomonas aeruginosa. Journal of basic microbiology, 2005, Volume: 45, Issue:5 Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia; Cystic Fibrosis; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	2005
Using the ROC curve for gauging treatment effect in clinical trials. Statistics in medicine, 2006, Feb-28, Volume: 25, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Age Factors; Anti-Bacterial Agents; Child; Clinical Trials, Phase III as Topic; Cystic Fibrosis; Data Interpretation, Statistical; Female; Forced Expiratory Volume; Humans; Male; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; ROC Curve; Statistics, Nonparametric; Tobramycin; Treatment Outcome	2006
The effects of intravenous tobramycin on renal tubular function in children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2005, Volume: 4, Issue:4 Topics: Acetylglucosaminidase; Adolescent; Analysis of Variance; Anti-Bacterial Agents; Biomarkers; Child; Child, Preschool; Creatinine; Cystic Fibrosis; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney Function Tests; Kidney Tubules, Proximal; Lung Diseases; Magnesium; Male; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Tobramycin; Treatment Outcome	2005
Effect of oxygen limitation on the in vitro antimicrobial susceptibility of clinical isolates of Pseudomonas aeruginosa grown planktonically and as biofilms. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2005, Volume: 24, Issue:10 Topics: Aerobiosis; Anaerobiosis; Anti-Bacterial Agents; Biofilms; Cystic Fibrosis; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Oxygen; Plankton; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2005
Routine susceptibility tests with ticarcillin and tobramycin in combination should be more appropriate than with each antibiotic alone in cystic fibrosis Pseudomonas aeruginosa. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl Topics: Anti-Bacterial Agents; Cystic Fibrosis; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Ticarcillin; Tobramycin	1989
Evaluation of the E test for the assessment of synergy of antibiotic combinations against multiresistant Pseudomonas aeruginosa isolates from cystic fibrosis patients. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2006, Volume: 25, Issue:1 Topics: Anti-Bacterial Agents; Ceftazidime; Cystic Fibrosis; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Humans; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reproducibility of Results; Thienamycins; Tobramycin	2006
Inhaled tobramycin-associated hearing loss in an adolescent with renal failure. The Pediatric infectious disease journal, 2006, Volume: 25, Issue:3 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Cystic Fibrosis; Hearing Loss, Sensorineural; Humans; Male; Renal Insufficiency; Tobramycin	2006
Towards zero prevalence of chronic Pseudomonas aeruginosa infection in children with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2006, Volume: 5, Issue:4 Topics: Administration, Inhalation; Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Female; Humans; Male; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin	2006
Breast-feeding in a woman with cystic fibrosis undergoing antibiotic intravenous treatment. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2006, Volume: 19, Issue:6 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Diagnosis, Differential; Female; Humans; Infant, Newborn; Infusions, Intravenous; Male; Milk, Human; Pregnancy; Pregnancy Complications, Infectious; Prenatal Diagnosis; Pseudomonas Infections; Tobramycin	2006
Therapeutic drug monitoring of once daily tobramycin in cystic fibrosis--caution with trough concentrations. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2007, Volume: 6, Issue:2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Child; Cystic Fibrosis; Drug Administration Schedule; Drug Monitoring; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Pseudomonas Infections; Sputum; Tobramycin	2007
Laboratory parameter profiles among patients with cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2007, Volume: 6, Issue:2 Topics: Adolescent; Alanine Transaminase; Anti-Bacterial Agents; Aspartate Aminotransferases; Child; Clinical Laboratory Techniques; Clinical Trials, Phase III as Topic; Cross-Sectional Studies; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Double-Blind Method; Female; Humans; Liver Function Tests; Longitudinal Studies; Male; Placebos; Reference Values; Tobramycin	2007
Measurement of urinary N-acetyl-b-D-glucosaminidase in adult patients with cystic fibrosis: before, during and after treatment with intravenous antibiotics. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2007, Volume: 6, Issue:1 Topics: Acetylglucosaminidase; Adolescent; Adult; Anti-Bacterial Agents; Colistin; Creatinine; Cystic Fibrosis; Diabetes Mellitus; Female; Humans; Kidney Tubules; Kidney Tubules, Proximal; Male; Prospective Studies; Tobramycin	2007
Pharmacokinetic profile of once daily intravenous tobramycin in children with cystic fibrosis. Journal of paediatrics and child health, 2006, Volume: 42, Issue:10 Topics: Adolescent; Adult; Algorithms; Anti-Bacterial Agents; Child; Cystic Fibrosis; Drug Administration Schedule; Humans; Injections, Intravenous; Tobramycin	2006
Inhaled tobramycin solution-associated recurrent eosinophilia and severe persistent bronchospasm in a patient with cystic fibrosis: a case report. BMC pediatrics, 2007, Mar-02, Volume: 7 Topics: Administration, Inhalation; Bronchial Spasm; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Male; Pneumonia, Bacterial; Prednisone; Pulmonary Eosinophilia; Recurrence; Risk Assessment; Severity of Illness Index; Tobramycin	2007
Pharmacokinetic modelling of a once-daily dosing regimen for intravenous tobramycin in paediatric cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:6 Topics: Adolescent; Anti-Bacterial Agents; Area Under Curve; Child; Computer Simulation; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Lung Diseases; Male; Models, Statistical; Nutritional Status; Pancreas; Retrospective Studies; Sample Size; Tobramycin	2007
Duration of treatment effect after tobramycin solution for inhalation in young children with cystic fibrosis. Pediatric pulmonology, 2007, Volume: 42, Issue:7 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child, Preschool; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Solutions; Time Factors; Tobramycin	2007
Acute renal failure in people with cystic fibrosis. Thorax, 2007, Volume: 62, Issue:6 Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Tobramycin	2007
Pharmacoscintigraphic and pharmacokinetic evaluation of tobramycin DPI formulations in cystic fibrosis patients. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 68, Issue:2 Topics: Adult; Anti-Bacterial Agents; Cross-Over Studies; Cystic Fibrosis; Female; Humans; Male; Powders; Radionuclide Imaging; Tobramycin	2008
Incidence and risk factors for multiple antibiotic-resistant Pseudomonas aeruginosa in cystic fibrosis. Chest, 2007, Volume: 132, Issue:2 Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Confidence Intervals; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Female; Follow-Up Studies; Humans; Incidence; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Risk Factors; Tobramycin; United States	2007
Effect of pH on the antimicrobial susceptibility of planktonic and biofilm-grown clinical Pseudomonas aeruginosa isolates. British journal of biomedical science, 2007, Volume: 64, Issue:3 Topics: Anti-Bacterial Agents; Biofilms; Ceftazidime; Cystic Fibrosis; Humans; Hydrogen-Ion Concentration; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2007
Target concentration intervention is needed for tobramycin dosing in paediatric patients with cystic fibrosis--a population pharmacokinetic study. British journal of clinical pharmacology, 2008, Volume: 65, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Body Weight; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Injections, Intravenous; Male; Models, Chemical; Predictive Value of Tests; Retrospective Studies; Tobramycin; Treatment Outcome	2008
In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cells. Infection and immunity, 2008, Volume: 76, Issue:4 Topics: Anti-Bacterial Agents; Antiporters; Bacterial Proteins; Biofilms; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Oxidoreductases; Protein Array Analysis; Pseudomonas aeruginosa; Tobramycin; Transcription, Genetic	2008
In vitro activity of antibiotic combinations against Pseudomonas aeruginosa biofilm and planktonic cultures. International journal of antimicrobial agents, 2008, Volume: 31, Issue:4 Topics: Anti-Bacterial Agents; Biofilms; Clarithromycin; Cystic Fibrosis; Drug Combinations; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Polymyxin B; Pseudomonas aeruginosa; Tobramycin	2008
Successful treatment of cepacia syndrome with combination nebulised and intravenous antibiotic therapy. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2008, Volume: 7, Issue:5 Topics: Adult; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Meropenem; Nebulizers and Vaporizers; Syndrome; Thienamycins; Tobramycin	2008
The DeltaF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availability. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:1 Topics: Anti-Bacterial Agents; Biofilms; Cells, Cultured; Coculture Techniques; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Resistance, Microbial; Epithelial Cells; Humans; Iron; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Mucosa; Tobramycin	2008
Cystic fibrosis: ironing out the problem of infection? American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:1 Topics: Anti-Bacterial Agents; Biofilms; Cells, Cultured; Coculture Techniques; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Resistance, Microbial; Epithelial Cells; Humans; Iron; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Mucosa; Tobramycin	2008
Moxalactam-tobramycin-resistant Pseudomonas aeruginosa isolates in patients with cystic fibrosis. Clinical pediatrics, 1983, Volume: 22, Issue:9 Topics: Adolescent; Anti-Bacterial Agents; Cephalosporins; Cephamycins; Child; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Male; Moxalactam; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	1983
Clinical results and pharmacokinetics of ceftazidime treatment in patients with cystic fibrosis. The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A Topics: Adolescent; Adult; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Half-Life; Humans; Kinetics; Pseudomonas Infections; Respiratory Tract Infections; Sputum; Tobramycin	1983
Ceftazidime alone and in combination in patients with cystic fibrosis: lack of efficacy in treatment of severe respiratory infections caused by Pseudomonas cepacia. The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A Topics: Adolescent; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Piperacillin; Pseudomonas Infections; Respiratory Tract Infections; Sulfamethoxazole; Tobramycin; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1983
Ceftazidime - a significant advance in the treatment of cystic fibrosis. The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A Topics: Adolescent; Adult; Ceftazidime; Cephalosporins; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Floxacillin; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Staphylococcal Infections; Tobramycin	1983
Tobramycin and carbenicillin compared with gentamicin and carbenicillin in the treatment of infection with Pseudomonas aeruginosa in adult patients with cystic fibrosis. British journal of diseases of the chest, 1983, Volume: 77, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbenicillin; Cystic Fibrosis; Drug Therapy, Combination; Female; Gentamicins; Humans; Lung Diseases; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1983
Treatment of chronic pseudomonas aeruginosa infection in cystic fibrosis patients with ceftazidime and tobramycin. Scandinavian journal of infectious diseases, 1983, Volume: 15, Issue:3 Topics: Adolescent; Adult; Ceftazidime; Cephalosporins; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1983
beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment. Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:5 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carrier Proteins; Cystic Fibrosis; Female; Hexosyltransferases; Humans; Muramoylpentapeptide Carboxypeptidase; Penicillin G; Penicillin Resistance; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Piperacillin; Pseudomonas aeruginosa; Sputum; Tobramycin	1981
Chemotherapy against Pseudomonas aeruginosa in cystic fibrosis. A study of carbenicillin, azlocillin or piperacillin in combination with tobramycin. European journal of respiratory diseases, 1982, Volume: 63, Issue:2 Topics: Anti-Bacterial Agents; Azlocillin; Carbenicillin; Cystic Fibrosis; Drug Therapy, Combination; Humans; Penicillins; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Recurrence; Tobramycin	1982
Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection. Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:5 Topics: Adult; Anti-Bacterial Agents; Carbenicillin; Cefsulodin; Cephalosporins; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Peak Expiratory Flow Rate; Pseudomonas Infections; Tobramycin	1983
Azlocillin in cystic fibrosis. Israel journal of medical sciences, 1983, Volume: 19, Issue:11 Topics: Adolescent; Adult; Azlocillin; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Female; Gentamicins; Humans; Male; Penicillins; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	1983
Are measurements of urine enzymes useful during aminoglycoside therapy? Pediatric research, 1981, Volume: 15, Issue:9 Topics: Acetylglucosaminidase; Adolescent; Adult; alpha-L-Fucosidase; Aminoglycosides; beta-Galactosidase; Child; Child, Preschool; Cystic Fibrosis; Female; Gentamicins; Glycoside Hydrolases; Humans; Kidney; Lung Diseases; Male; Middle Aged; Muramidase; Pseudomonas Infections; Tobramycin	1981
Activities of various beta-lactams and aminoglycosides, alone and in combination, against isolates of Pseudomonas aeruginosa from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:6 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1982
Ototoxicity of aminoglucoside antibiotics in long-term treatment for cystic fibrosis. International journal of pediatric otorhinolaryngology, 1980, Volume: 2, Issue:3 Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Gentamicins; Hearing Loss; Hearing Loss, Conductive; Hearing Loss, Sensorineural; Humans; Long-Term Care; Tobramycin	1980
Pharmacokinetics of tobramycin in cystic fibrosis. The Journal of pediatrics, 1982, Volume: 100, Issue:2 Topics: Adolescent; Adult; Aminoglycosides; Anti-Bacterial Agents; Biopharmaceutics; Body Surface Area; Body Weight; Child; Child, Preschool; Creatinine; Cystic Fibrosis; Female; Humans; Lung Diseases; Male; Pseudomonas Infections; Tobramycin	1982
Aminoglycoside dosage in pediatric patients:considerations regarding pharmacokinetic-based dose adjustment in patients requiring high versus low dose therapy. Developmental pharmacology and therapeutics, 1981, Volume: 3, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cystic Fibrosis; Gentamicins; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Leukemia; Prospective Studies; Retrospective Studies; Tobramycin	1981
Gentamicin and tobramycin compared in the treatment of mucoid pseudomonas lung infections in cystic fibrosis. Archives of disease in childhood, 1980, Volume: 55, Issue:8 Topics: Adolescent; Anti-Bacterial Agents; Carbenicillin; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Gentamicins; Humans; Lung Diseases; Pseudomonas Infections; Tobramycin	1980
Macromolecular mechanisms of sputum inhibition of tobramycin activity. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:1 Topics: Adult; Animals; Cattle; Child; Cystic Fibrosis; Deoxyribonuclease I; DNA; Gastric Mucins; Humans; In Vitro Techniques; Kinetics; Pseudomonas aeruginosa; Recombinant Proteins; Sputum; Swine; Thymus Gland; Tobramycin	1995
Management of chronic sinusitis in cystic fibrosis. The Laryngoscope, 1995, Volume: 105, Issue:4 Pt 1 Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Clinical Protocols; Combined Modality Therapy; Cystic Fibrosis; Endoscopy; Humans; Lung Transplantation; Maxillary Sinus; Nasal Polyps; Nasal Septum; Pneumonia, Bacterial; Preoperative Care; Pseudomonas Infections; Respiratory Tract Infections; Rhinitis; Sinusitis; Sodium Chloride; Therapeutic Irrigation; Tobramycin; Turbinates	1995
Nebulizer performance: AFLM study. Association Française de Lutte contre la Mucoviscidose. Respiration; international review of thoracic diseases, 1995, Volume: 62 Suppl 1 Topics: Administration, Inhalation; Aerosols; Amiloride; Colistin; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Tobramycin	1995
[Characterization by isotope method of the performance of the pneumatic nebulizer NL9 Atomizer in the production of colistin, tobramycin and amiloride aerosols]. Revue des maladies respiratoires, 1994, Volume: 11, Issue:6 Topics: Aerosols; Amiloride; Colistin; Cystic Fibrosis; Evaluation Studies as Topic; Humans; Nebulizers and Vaporizers; Particle Size; Sodium Pertechnetate Tc 99m; Surface Tension; Tobramycin	1994
Development of antibiotic resistance in Pseudomonas aeruginosa during two decades of antipseudomonal treatment at the Danish CF Center. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1994, Volume: 102, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbenicillin; Ceftazidime; Ciprofloxacin; Cystic Fibrosis; Denmark; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Piperacillin; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1994
Suggestions for the optimization of the initial tobramycin dose in adolescent and adult patients with cystic fibrosis. Therapeutic drug monitoring, 1994, Volume: 16, Issue:2 Topics: Adolescent; Adult; Body Weight; Cystic Fibrosis; Dose-Response Relationship, Drug; Female; Humans; Male; Mathematics; Pseudomonas Infections; Regression Analysis; Respiratory Tract Infections; Retrospective Studies; Tobramycin	1994
Absolute bioavailability and absorption characteristics of aerosolized tobramycin in adults with cystic fibrosis. Journal of clinical pharmacology, 1994, Volume: 34, Issue:3 Topics: Administration, Inhalation; Adult; Aerosols; Biological Availability; Ceftazidime; Cystic Fibrosis; Female; Humans; Intestinal Absorption; Male; Metabolic Clearance Rate; Nebulizers and Vaporizers; Tobramycin	1994
Nebulizer delivery of tobramycin to the lower respiratory tract. Pediatric pulmonology, 1994, Volume: 17, Issue:5 Topics: Adolescent; Adult; Aerosols; Child; Cystic Fibrosis; Drug Carriers; Female; Gases; Humans; Male; Nebulizers and Vaporizers; Particle Size; Respiratory System; Sputum; Tobramycin	1994
The quantitative distribution of nebulized antibiotic in the lung in cystic fibrosis. Respiratory medicine, 1994, Volume: 88, Issue:3 Topics: Adolescent; Adult; Aerosols; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Lung; Male; Nebulizers and Vaporizers; Radionuclide Imaging; Sputum; Technetium Compounds; Tobramycin	1994
Aerosolized tobramycin in patients with cystic fibrosis. The New England journal of medicine, 1993, Nov-25, Volume: 329, Issue:22 Topics: Aerosols; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Pseudomonas; Tobramycin; Xanthomonas	1993
Validation of tobramycin monitoring in adolescent and adult patients with cystic fibrosis. Therapeutic drug monitoring, 1993, Volume: 15, Issue:1 Topics: Adolescent; Adult; Aging; Cystic Fibrosis; Drug Administration Schedule; Drug Delivery Systems; Drug Monitoring; Female; Humans; Male; Models, Biological; Predictive Value of Tests; Reproducibility of Results; Retrospective Studies; Tobramycin	1993
Assessment of potential ototoxicity following high-dose nebulized tobramycin in patients with cystic fibrosis. The Journal of antimicrobial chemotherapy, 1993, Volume: 31, Issue:3 Topics: Action Potentials; Adolescent; Adult; Audiometry, Evoked Response; Child; Child, Preschool; Cochlea; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Tobramycin	1993
Old hopes and new horizons for treating cystic fibrosis. Lancet (London, England), 1996, Jun-01, Volume: 347, Issue:9014 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genetic Therapy; Humans; Liposomes; Tobramycin; Uridine Triphosphate	1996
[Comparative study of the performance and ergonomics of nebulizers in cystic fibrosis]. Revue des maladies respiratoires, 1996, Volume: 13, Issue:2 Topics: Administration, Inhalation; Adult; Aerosols; Amiloride; Anti-Bacterial Agents; Child; Colistin; Cystic Fibrosis; Diuretics; Equipment Design; Ergonomics; Humans; Materials Testing; Nebulizers and Vaporizers; Particle Size; Tobramycin	1996
Prospective evaluation of a dose prediction algorithm for intravenous tobramycin in adolescent and adult patients with cystic fibrosis. Therapeutic drug monitoring, 1996, Volume: 18, Issue:2 Topics: Adolescent; Adult; Algorithms; Anti-Bacterial Agents; Body Weight; Cystic Fibrosis; Female; Humans; Injections, Intravenous; Male; Middle Aged; Prospective Studies; Tobramycin	1996
Bronchial constriction after nebulized tobramycin preparations and saline in patients with cystic fibrosis. European journal of pediatrics, 1996, Volume: 155, Issue:7 Topics: Adolescent; Adult; Aerosols; Airway Obstruction; Anti-Bacterial Agents; Bronchodilator Agents; Case-Control Studies; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Linear Models; Male; Prospective Studies; Pseudomonas Infections; Respiratory Mechanics; Statistics, Nonparametric; Tobramycin	1996
Adaptive resistance to tobramycin in Pseudomonas aeruginosa lung infection in cystic fibrosis. The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:6 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Drug Resistance, Microbial; Female; Humans; Lung Diseases; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Time Factors; Tobramycin	1996
Creatinine clearance as predictor of tobramycin elimination in adult patients with cystic fibrosis. Therapeutic drug monitoring, 1996, Volume: 18, Issue:5 Topics: Adult; Anti-Bacterial Agents; Creatinine; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Regression Analysis; Tobramycin	1996
The choice of jet nebulizer, nebulizing flow, and addition of albuterol affects the output of tobramycin aerosols. Chest, 1997, Volume: 111, Issue:5 Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aerosols; Albuterol; Anti-Bacterial Agents; Calibration; Cystic Fibrosis; Disposable Equipment; Drug Combinations; Equipment Design; Humans; Lasers; Lung; Nebulizers and Vaporizers; Particle Size; Respiration; Rheology; Sodium Chloride; Surface Tension; Tobramycin	1997
Pharmacokinetic modelling of intravenous tobramycin in adolescent and adult patients with cystic fibrosis using the nonparametric expectation maximization (NPEM) algorithm. Pharmacy world & science : PWS, 1997, Volume: 19, Issue:3 Topics: Adolescent; Adult; Algorithms; Anti-Bacterial Agents; Area Under Curve; Bayes Theorem; Biological Availability; Computer Simulation; Creatinine; Cystic Fibrosis; Data Collection; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Male; Sample Size; Statistics as Topic; Statistics, Nonparametric; Tobramycin	1997
Pharmacokinetics and safety of tobramycin after once-daily administration in patients with cystic fibrosis. Chest, 1997, Nov-05, Volume: 112, Issue:5 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cost-Benefit Analysis; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fluorescence Polarization Immunoassay; Half-Life; Humans; Length of Stay; Male; Respiratory Tract Infections; Safety; Tobramycin; Treatment Outcome	1997
Loss of spiral ganglion cells as primary manifestation of aminoglycoside ototoxicity. Hearing research, 1998, Volume: 115, Issue:1-2 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Gentamicins; Hair Cells, Auditory; Hearing Loss, High-Frequency; Humans; Nerve Degeneration; Spiral Ganglion; Temporal Bone; Tobramycin	1998
From the Food and Drug Administration. JAMA, 1998, Mar-04, Volume: 279, Issue:9 Topics: Administration, Inhalation; Advertising; Anti-Bacterial Agents; Cystic Fibrosis; Drug Approval; Drug Industry; Drugs, Generic; Humans; Hypersensitivity; Latex; Telecommunications; Tobramycin; United States; United States Food and Drug Administration	1998
Contralateral suppression of distortion product otoacoustic emissions in children with cystic fibrosis: effects of tobramycin. Journal of the American Academy of Audiology, 1998, Volume: 9, Issue:3 Topics: Acoustic Impedance Tests; Adolescent; Analysis of Variance; Anti-Bacterial Agents; Audiometry; Auditory Threshold; Child; Cochlea; Cystic Fibrosis; Follow-Up Studies; Humans; Retrospective Studies; Tobramycin	1998
Microbiology of sputum from patients at cystic fibrosis centers in the United States. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Child; Clinical Trials, Phase III as Topic; Cross-Sectional Studies; Cystic Fibrosis; Drug Resistance, Microbial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Sputum; Tobramycin; United States	1998
Hypomagnesaemic tetany associated with repeated courses of intravenous tobramycin in a patient with cystic fibrosis. Respiratory medicine, 1998, Volume: 92, Issue:3 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Hypocalcemia; Infusions, Intravenous; Magnesium; Tetany; Tobramycin	1998
Comparative in vitro activities of meropenem, imipenem, temocillin, piperacillin, and ceftazidime in combination with tobramycin, rifampin, or ciprofloxacin against Burkholderia cepacia isolates from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2 Topics: Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Ciprofloxacin; Cystic Fibrosis; Drug Synergism; Drug Therapy, Combination; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillins; Piperacillin; Rifampin; Thienamycins; Tobramycin	1999
Cystic fibrosis: looking for another breakthrough. Tecnologica (Chicago, Ill.), 1998 Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bone Diseases; Child; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxyribonuclease I; Drainage, Postural; Forecasting; Genetic Therapy; Health Care Costs; Humans; Lung Transplantation; Physical Therapy Modalities; Tobramycin; Treatment Outcome; United States	1998
Tobramycin pharmacokinetics in patients with cystic fibrosis preceding and following lung transplantation. Therapeutic drug monitoring, 1999, Volume: 21, Issue:2 Topics: Adult; Anti-Bacterial Agents; Bayes Theorem; Cystic Fibrosis; Female; Humans; Lung Transplantation; Male; Medical Records; Postoperative Care; Premedication; Retrospective Studies; Tobramycin	1999
Development of resistance and cross-resistance in Pseudomonas aeruginosa exposed to subinhibitory antibiotic concentrations. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1999, Volume: 107, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azlocillin; Ceftazidime; Cephalosporins; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Microbial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Penicillins; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1999
Aminoglycoside-associated hypomagnesaemia in children with cystic fibrosis. Acta paediatrica (Oslo, Norway : 1992), 1999, Volume: 88, Issue:7 Topics: Acute Disease; Anti-Bacterial Agents; Child, Preschool; Cystic Fibrosis; Female; Humans; Kidney Tubules; Magnesium; Magnesium Deficiency; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1999
Ability of azlocillin and tobramycin in combination to delay or prevent resistance development in Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:3 Topics: Anti-Bacterial Agents; Azlocillin; Cystic Fibrosis; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Penicillins; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1999
Inhalation of tobramycin in cystic fibrosis. Part 1: the choice of a nebulizer. International journal of pharmaceutics, 1999, Nov-05, Volume: 189, Issue:2 Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Kinetics; Nebulizers and Vaporizers; Osmolar Concentration; Particle Size; Pressure; Tobramycin; Ultrasonics	1999
Inhalation of tobramycin in cystic fibrosis. Part 2: optimization of the tobramycin solution for a jet and an ultrasonic nebulizer. International journal of pharmaceutics, 1999, Nov-05, Volume: 189, Issue:2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Cystic Fibrosis; Dose-Response Relationship, Drug; Fluorescence Polarization Immunoassay; Humans; Kinetics; Nebulizers and Vaporizers; Particle Size; Pressure; Solutions; Tobramycin; Ultrasonics	1999
Characterization of a Pseudomonas aeruginosa efflux pump contributing to aminoglycoside impermeability. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:12 Topics: Anti-Bacterial Agents; Blotting, Southern; Chromosome Mapping; Culture Media; Cystic Fibrosis; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Humans; Microbial Sensitivity Tests; Mutation; Permeability; Phenotype; Plasmids; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Tobramycin; Transcriptional Activation; Up-Regulation	1999
Falsely elevated serum tobramycin concentrations in cystic fibrosis patients treated with concurrent intravenous and inhaled tobramycin. Pediatric pulmonology, 2000, Volume: 29, Issue:1 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Cystic Fibrosis; Drug Monitoring; False Negative Reactions; Female; Humans; Injections, Intravenous; Male; Tobramycin	2000
Optimal tobramycin dosage in patients with cystic fibrosis--evidence for predictability based on previous drug monitoring. Infection, 1999, Volume: 27, Issue:4-5 Topics: Adult; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Monitoring; Female; Follow-Up Studies; Humans; Male; Pneumonia, Bacterial; Predictive Value of Tests; Pseudomonas Infections; Retrospective Studies; Secondary Prevention; Tobramycin; Treatment Outcome	1999
Accounting for radioactivity before and after nebulization of tobramycin to insure accuracy of quantification of lung deposition. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine, 2000,Fall, Volume: 13, Issue:3 Topics: Adult; Aerosols; Anti-Bacterial Agents; Cystic Fibrosis; Gamma Cameras; Humans; Lung; Nebulizers and Vaporizers; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Aggregated Albumin; Tobramycin	2000
Survival of Stenotrophomonas maltophilia following exposure to concentrations of tobramycin used in aerosolized therapy for cystic fibrosis patients. International journal of antimicrobial agents, 2001, Volume: 17, Issue:1 Topics: Administration, Inhalation; Aerosols; Analysis of Variance; Anti-Bacterial Agents; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Stenotrophomonas maltophilia; Tobramycin	2001
Effect of size and disease on estimated deposition of drugs administered using jet nebulization in children with cystic fibrosis. Chest, 2001, Volume: 119, Issue:4 Topics: Administration, Inhalation; Adolescent; Aerosols; Anti-Bacterial Agents; Body Constitution; Child; Cystic Fibrosis; Equipment Design; Humans; Lung; Models, Theoretical; Nebulizers and Vaporizers; Pulmonary Ventilation; Respiratory Mechanics; Tobramycin	2001
Aminoglycoside ototoxicity. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2001, Volume: 22, Issue:2 Topics: Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Cystic Fibrosis; Fatal Outcome; Female; Hearing Loss, Sensorineural; Humans; Organ of Corti; Tobramycin	2001
Occurrence and risk of cochleotoxicity in cystic fibrosis patients receiving repeated high-dose aminoglycoside therapy. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:9 Topics: Adolescent; Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Child; Cystic Fibrosis; Deafness; Drug Overdose; Drug Therapy, Combination; Drug Utilization; Gentamicins; Hearing; Humans; Radio Waves; Tobramycin	2001
Administration of aerosolized antibiotics in cystic fibrosis patients. Chest, 2001, Volume: 120, Issue:3 Suppl Topics: Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Nebulizers and Vaporizers; Opportunistic Infections; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome	2001
Genotypic characterization of Pseudomonas aeruginosa strains recovered from patients with cystic fibrosis after initial and subsequent colonization. Pediatric pulmonology, 2001, Volume: 32, Issue:4 Topics: Administration, Inhalation; Administration, Oral; Ceftazidime; Child; Child, Preschool; Chronic Disease; Colistin; Colony Count, Microbial; Cystic Fibrosis; DNA, Bacterial; Drug Therapy, Combination; Electrophoresis, Gel, Pulsed-Field; Female; Genotype; Humans; Imipenem; Infant; Male; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Assessment; Tobramycin	2001
Effect of inhaled tobramycin on early Pseudomonas aeruginosa colonisation in patients with cystic fibrosis. Lancet (London, England), 2001, Sep-22, Volume: 358, Issue:9286 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Humans; Infant; Lung Diseases; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	2001
The treatment of cystic fibrosis--step by step. The Journal of pediatrics, 2001, Volume: 139, Issue:4 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child, Preschool; Cystic Fibrosis; Humans; Infant; Tobramycin	2001
Comparison of two culture methods for detection of tobramycin-resistant gram-negative organisms in the sputum of patients with cystic fibrosis. Journal of clinical microbiology, 2002, Volume: 40, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacteriological Techniques; Child; Colony Count, Microbial; Culture Media; Cystic Fibrosis; Drug Resistance, Bacterial; False Positive Reactions; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Sputum; Tobramycin	2002
Lack of concordance in the use and monitoring of intravenous aminoglycosides in UK cystic fibrosis centers. Pediatric pulmonology, 2002, Volume: 33, Issue:2 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Deafness; Humans; Pseudomonas Infections; Tobramycin; United Kingdom	2002
[Inhalational antibiotic therapy in mucoviscidosis. Apropos of a galenic form of tobramycin]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2001, Volume: 8 Suppl 5 Topics: Administration, Inhalation; Bronchitis; Child; Child, Preschool; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Infant; Infant, Newborn; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2001
In vitro activity of the aerosolized agents colistin and tobramycin and five intravenous agents against Pseudomonas aeruginosa isolated from cystic fibrosis patients in southwestern Germany. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:2 Topics: Aerosols; Anti-Bacterial Agents; Colistin; Cystic Fibrosis; Drug Evaluation, Preclinical; Germany; Humans; Injections, Intravenous; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	2002
Early Pseudomonas aeruginosa colonisation in cystic fibrosis patients. Lancet (London, England), 2002, Feb-16, Volume: 359, Issue:9306 Topics: Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	2002
Early Pseudomonas aeruginosa colonisation in cystic fibrosis patients. Lancet (London, England), 2002, Feb-16, Volume: 359, Issue:9306 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Ciprofloxacin; Clinical Trials as Topic; Colistin; Cystic Fibrosis; Humans; Pseudomonas Infections; Tobramycin	2002
Pharmaceutical considerations in aerosol drug delivery. Pharmacotherapy, 2002, Volume: 22, Issue:3 Pt 2 Topics: Administration, Inhalation; Aerosols; Age Factors; Aminoglycosides; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Cystic Fibrosis; Dosage Forms; Dose-Response Relationship, Drug; Drug Compounding; Drug Delivery Systems; Humans; Nebulizers and Vaporizers; Tobramycin	2002
Treatment options for cystic fibrosis: case study and panel discussion. Pharmacotherapy, 2002, Volume: 22, Issue:3 Pt 2 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Humans; Macrolides; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Tobramycin; Treatment Outcome	2002
Normal volume of distribution of tobramycin in a mother and daughter with a CFTR splice mutation (1717 - 1G --> A). Pediatric pulmonology, 2002, Volume: 33, Issue:4 Topics: Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Mutation; Peptide Fragments; Tobramycin	2002
Hypersensitivity to inhaled TOBI following reaction to gentamicin. Pediatric pulmonology, 2002, Volume: 33, Issue:4 Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Cystic Fibrosis; Desensitization, Immunologic; Drug Eruptions; Gentamicins; Humans; Male; Pseudomonas Infections; Skin Tests; Tobramycin	2002
Once-daily tobramycin. Pediatric pulmonology, 2002, Volume: 33, Issue:5 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Humans; Tobramycin	2002
Once-daily tobramycin monotherapy in cystic fibrosis. Pediatric pulmonology, 2002, Volume: 33, Issue:5 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Humans; Tobramycin	2002
Factors affecting the incidence of Stenotrophomonas maltophilia isolation in cystic fibrosis. Chest, 2002, Volume: 121, Issue:6 Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Cystic Fibrosis; Female; Gram-Negative Bacterial Infections; Humans; Incidence; Male; Retrospective Studies; Stenotrophomonas maltophilia; Tobramycin	2002
Mucoid Pseudomonas aeruginosa and cystic fibrosis: resistance of the mucoid from to carbenicillin, flucloxacillin and tobramycin and the isolation of mucoid variants in vitro. The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:3 Topics: Anti-Bacterial Agents; Carbenicillin; Chemical Phenomena; Chemistry, Physical; Cloxacillin; Cystic Fibrosis; Floxacillin; Humans; Penicillin Resistance; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Tobramycin	1978
Pseudomonas aeruginosa infection: pathogenesis and therapy. Comprehensive therapy, 1979, Volume: 5, Issue:5 Topics: Bacterial Vaccines; Burns; Carbenicillin; Cross Infection; Cystic Fibrosis; Gentamicins; Humans; Immunosuppression Therapy; Pseudomonas aeruginosa; Pseudomonas Infections; Ticarcillin; Tobramycin; Wound Infection	1979
Chemotherapy of chronic infections with mucoid Pseudomonas aeruginosa in lower airways of patients with cystic fibrosis. Scandinavian journal of infectious diseases, 1979, Volume: 11, Issue:3 Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbenicillin; Child; Child, Preschool; Chronic Disease; Colistin; Cystic Fibrosis; Drug Evaluation; Drug Therapy, Combination; Female; Gentamicins; Humans; Infant; Male; Pneumonia; Precipitins; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1979
Multiple of isolates of Pseudomonas aeruginosa with differing antimicrobial susceptibility patterns from patients with cystic fibrosis. The Journal of infectious diseases, 1979, Volume: 140, Issue:6 Topics: Adolescent; Adult; Carbenicillin; Child; Child, Preschool; Cystic Fibrosis; Gentamicins; Humans; Infant; Kanamycin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tetracycline; Ticarcillin; Time Factors; Tobramycin	1979
In vitro susceptibility of pseudomonas to four beta-lactamantibiotics (ampicillin, cephalothin, carbenicillin, piperacillin), to four aminoglycosides (kanamycin, amikacin, gentamicin, tobramycin) and to colimycin. Chemotherapy, 1979, Volume: 25, Issue:1 Topics: Amikacin; Aminoglycosides; Ampicillin; Carbenicillin; Cephalothin; Child; Colistin; Cystic Fibrosis; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pseudomonas; Sputum; Tobramycin	1979
Effects of sputum from patients with cystic fibrosis on the activity in vitro of 5 antimicrobial drugs on Pseudomonas aeruginosa. The American review of respiratory disease, 1978, Volume: 117, Issue:1 Topics: Anti-Bacterial Agents; Carbenicillin; Cystic Fibrosis; Gentamicins; Humans; Microbial Sensitivity Tests; Neomycin; Polymyxin B; Pseudomonas aeruginosa; Sputum; Tobramycin	1978
Evaluation of long term tobramycin therapy in patients with cystic fibrosis and advanced pulmonary disease. European journal of pediatrics, 1979, Apr-03, Volume: 130, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Female; Humans; Lung Diseases; Male; Pseudomonas Infections; Radiography; Respiratory Function Tests; Time Factors; Tobramycin	1979
Cystic fibrosis and hearing loss. Archives of otolaryngology (Chicago, Ill. : 1960), 1979, Volume: 105, Issue:6 Topics: Acoustic Impedance Tests; Adolescent; Adult; Audiometry; Auditory Threshold; Child; Cystic Fibrosis; Ear Ossicles; Ear, Middle; Female; Gentamicins; Hearing Loss; Hearing Loss, Conductive; Hearing Loss, Sensorineural; Humans; Male; Pressure; Stapes; Tobramycin; Tympanic Membrane	1979
The use and abuse of antibiotics, including in management of pulmonary manifestations in cystic fibrosis. Monographs in paediatrics, 1979, Volume: 10 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Humans; Lung Diseases; Substance-Related Disorders; Tobramycin	1979
Long-term tobramycin therapy in patients with cystic fibrosis and advanced pulmonary disease. Monographs in paediatrics, 1979, Volume: 10 Topics: Anti-Bacterial Agents; Cystic Fibrosis; Humans; Infant; Lung Diseases; Pseudomonas Infections; Time Factors; Tobramycin	1979
Tobramycin ototoxicity. Repeated courses of high dosage treatment in children with cystic fibrosis. The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:3 Topics: Anti-Bacterial Agents; Child; Cystic Fibrosis; Drug Administration Schedule; Ear Diseases; Female; Hearing Disorders; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	1979
[Pseudomonas infections in lungs of children born with cystic fibrosis. Effects and adverse effects during antibiotic therapy with tobramycin and carbenicillin]. Ugeskrift for laeger, 1979, Jul-16, Volume: 141, Issue:29 Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbenicillin; Child; Child, Preschool; Cystic Fibrosis; Drug Evaluation; Female; Humans; Infant; Male; Pneumonia; Prognosis; Pseudomonas Infections; Tobramycin	1979
High dosage tobramycin treatment of children with cystic fibrosis. Bacteriological effect and clinical ototoxicity. International journal of pediatric otorhinolaryngology, 1979, Volume: 1, Issue:1 Topics: Anti-Bacterial Agents; Carbenicillin; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	1979
Tobramycin in treatment of infections due to Pseudomonas aeruginosa in patients with cystic fibrosis. The Journal of infectious diseases, 1976, Volume: 134 Suppl Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Female; Humans; Lung Diseases; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1976
Tobramycin and ticarcillin therapy for exacerbations of pulmonary disease in patients with cystic fibrosis. The Journal of infectious diseases, 1976, Volume: 134 Suppl Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Lung Diseases; Male; Penicillins; Pseudomonas aeruginosa; Pseudomonas Infections; Ticarcillin; Tobramycin	1976
Treatment of pseudomonas infections in cystic fibrosis using tobramycin. Scottish medical journal, 1976, Volume: 21, Issue:2 Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Humans; Infant; Pseudomonas Infections; Tobramycin	1976
Tobramycin therapy of infections due to Pseudomonas aeruginosa in patients with cystic fibrosis: effect of dosage and concentration of antibiotic in sputum. The Journal of infectious diseases, 1976, Volume: 134 Suppl Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Humans; Infant; Pseudomonas Infections; Sputum; Tobramycin	1976
Post-antibiotic effect of ceftazidime, ciprofloxacin, imipenem, piperacillin and tobramycin for Pseudomonas cepacia. The Journal of antimicrobial chemotherapy, 1992, Volume: 30, Issue:5 Topics: Burkholderia cepacia; Ceftazidime; Ciprofloxacin; Cystic Fibrosis; Humans; Imipenem; Microbial Sensitivity Tests; Piperacillin; Tobramycin	1992
New peripherally inserted midline catheter: a better alternative for intravenous antibiotic therapy in patients with cystic fibrosis. Pediatric pulmonology, 1992, Volume: 12, Issue:4 Topics: Adolescent; Adult; Catheterization, Peripheral; Catheters, Indwelling; Ceftazidime; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Elbow; Female; Humans; Imipenem; Infusions, Intravenous; Male; Piperacillin; Time Factors; Tobramycin	1992
Comparison of inhibitory and bactericidal activity of antipseudomonal antibiotics against Pseudomonas aeruginosa isolates from cystic fibrosis patients. Chemotherapy, 1990, Volume: 36, Issue:3 Topics: Amikacin; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1990
[In vitro bactericidal activity of tobramycin and amikacin alone or in combination against Pseudomonas aeruginosa isolated from patients with cystic fibrosis]. Pathologie-biologie, 1990, Volume: 38, Issue:5 Topics: Amikacin; Anti-Bacterial Agents; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; In Vitro Techniques; Lactams; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tobramycin	1990
Variability of aminoglycosides pharmacokinesis in C.F. patients in relation with certain clinical parameters. Acta Universitatis Carolinae. Medica, 1990, Volume: 36, Issue:1-4 Topics: Amikacin; Anti-Bacterial Agents; Cystic Fibrosis; Female; Humans; Male; Pneumonia; Pseudomonas Infections; Tobramycin	1990
Assay of a urinary CF-lectin factor as a second diagnostic test for cystic fibrosis. The American journal of the medical sciences, 1990, Volume: 299, Issue:2 Topics: Adolescent; Adult; Chlorides; Chromatography, Gel; Chromatography, Ion Exchange; Cystic Fibrosis; Female; Humans; Lectins; Male; Molecular Weight; Sweat; Tobramycin	1990
Influence of infusion method on serum tobramycin concentrations in adults with cystic fibrosis. Clinical pharmacy, 1990, Volume: 9, Issue:7 Topics: Adult; Cystic Fibrosis; Humans; Infusions, Intravenous; Tobramycin	1990
Long-term tobramycin aerosol therapy in cystic fibrosis. Pediatric pulmonology, 1989, Volume: 6, Issue:2 Topics: Administration, Inhalation; Adolescent; Aerosols; Child; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin	1989
Treatment of pseudomonas aeruginosa colonisation in cystic fibrosis. Archives of disease in childhood, 1989, Volume: 64, Issue:7 Topics: Adolescent; Azlocillin; Child; Child, Preschool; Cystic Fibrosis; Drug Therapy, Combination; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Serotyping; Sputum; Time Factors; Tobramycin	1989
Regarding article by Earl and Sullivan. The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:6 Topics: Cystic Fibrosis; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Infusions, Intravenous; Tobramycin	1989
Analysis and HPLC fractionation of urine from patients with cystic fibrosis, chronic lung diseases and normal controls. Clinical biochemistry, 1989, Volume: 22, Issue:5 Topics: Adolescent; Adult; Biological Assay; Carbohydrates; Chemical Fractionation; Child; Chromatography, High Pressure Liquid; Chronic Disease; Creatinine; Cystic Fibrosis; Female; Humans; Hydrogen-Ion Concentration; Lung Diseases; Male; Proteinuria; Sialic Acids; Ticarcillin; Tobramycin	1989
Renal function in cystic fibrosis: proteinuria and enzymuria before and after tobramycin therapy. European journal of pediatrics, 1986, Volume: 145, Issue:6 Topics: Acetylglucosaminidase; Adolescent; Adult; Aminopeptidases; Azlocillin; CD13 Antigens; Child; Child, Preschool; Creatinine; Cystic Fibrosis; Female; Hexosaminidases; Humans; Kidney; Male; Proteinuria; Pseudomonas Infections; Tobramycin	1986
Evaluation of clinical pharmacokinetic services provided to children and adolescents with cystic fibrosis. The Journal of the Arkansas Medical Society, 1985, Volume: 82, Issue:5 Topics: Adolescent; Child; Cystic Fibrosis; Evaluation Studies as Topic; Female; Humans; Kinetics; Male; Monitoring, Physiologic; Pharmacology, Clinical; Random Allocation; Retrospective Studies; Tobramycin	1985
The binding of anti-pseudomonal antibiotics to macromolecules from cystic fibrosis sputum. The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:4 Topics: Ceftazidime; Cystic Fibrosis; DNA; Humans; In Vitro Techniques; Macromolecular Substances; Mucins; Sputum; Tobramycin	1988
An epidemic spread of multiresistant Pseudomonas aeruginosa in a cystic fibrosis centre. The Journal of antimicrobial chemotherapy, 1986, Volume: 17, Issue:4 Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Cross Infection; Cystic Fibrosis; Denmark; Disease Outbreaks; Drug Resistance, Microbial; Female; Humans; Lactams; Male; Microbial Sensitivity Tests; Patient Isolation; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1986
Facilitated detection of antibiotic-resistant Pseudomonas in cystic fibrosis sputum using homogenized specimens and antibiotic-containing media. Diagnostic microbiology and infectious disease, 1986, Volume: 5, Issue:4 Topics: Anti-Bacterial Agents; Azlocillin; Culture Media; Cystic Fibrosis; Humans; Penicillin Resistance; Pseudomonas aeruginosa; Sputum; Ticarcillin; Tobramycin	1986
Emergence of ceftriaxone-resistant strains of Pseudomonas aeruginosa in cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 1986, Volume: 18, Issue:5 Topics: Adolescent; Adult; beta-Lactamases; Ceftriaxone; Child; Cystic Fibrosis; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	1986
Ciprofloxacin in the treatment of Pseudomonas infection in cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl D Topics: Adolescent; Adult; Azlocillin; Ciprofloxacin; Cystic Fibrosis; Drug Therapy, Combination; Humans; Pseudomonas; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin	1986
Combined imipenem/cilastatin and tobramycin therapy of multiresistant Pseudomonas aeruginosa in cystic fibrosis. The Journal of antimicrobial chemotherapy, 1987, Volume: 19, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Bronchopneumonia; Child; Chronic Disease; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Cystic Fibrosis; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipenem; Kinetics; Male; Microbial Sensitivity Tests; Penicillin Resistance; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Thienamycins; Tobramycin	1987
In vitro activity of aztreonam combined with tobramycin and gentamicin against clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:9 Topics: Aztreonam; Cystic Fibrosis; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin	1987
Mechanism of Pseudomonas aeruginosa persistence during treatment with broad-spectrum cephalosporins of lung infections in patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:9 Topics: beta-Lactamases; Ceftazidime; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors; Tobramycin	1987
Cost savings and economic considerations using home intravenous antibiotic therapy for cystic fibrosis patients. Pediatric pulmonology, 1988, Volume: 4, Issue:2 Topics: Adolescent; Adult; Ceftazidime; Child; Cost-Benefit Analysis; Cystic Fibrosis; Home Care Services; Hospitalization; Humans; Infusions, Intravenous; Penicillins; Pseudomonas Infections; Ticarcillin; Tobramycin	1988
In vitro susceptibility of Pseudomonas aeruginosa from bacteremic and fibrocystic patients to four quinolones and five other antipseudomonal antibiotics. Scandinavian journal of infectious diseases, 1988, Volume: 20, Issue:5 Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Cystic Fibrosis; Drug Resistance, Microbial; Humans; Lactams; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Sepsis; Tobramycin	1988
Frontal sinus mucopyocele in cystic fibrosis. Ophthalmic plastic and reconstructive surgery, 1988, Volume: 4, Issue:4 Topics: Adolescent; Adult; Cystic Fibrosis; Diplopia; Exophthalmos; Female; Frontal Sinus; Humans; Male; Mucocele; Paranasal Sinus Diseases; Pseudomonas Infections; Suppuration; Tobramycin; Tomography, X-Ray Computed	1988
Long-term tobramycin aerosol therapy of chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis. Scandinavian journal of gastroenterology. Supplement, 1988, Volume: 143 Topics: Administration, Inhalation; Adolescent; Aerosols; Child; Cystic Fibrosis; Female; Humans; Male; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin	1988
Lack of correlation between objective indicators and clinical-response scores during antimicrobial therapy for acute pulmonary exacerbations of cystic fibrosis. Clinical pharmacy, 1988, Volume: 7, Issue:12 Topics: Anti-Bacterial Agents; Azlocillin; Aztreonam; Ciprofloxacin; Cystic Fibrosis; Humans; Tobramycin	1988
In vitro activity of amiloride combined with tobramycin against Pseudomonas isolates from patients with cystic fibrosis. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:3 Topics: Amiloride; Child; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas Infections; Tobramycin	1988
Individualized aminoglycoside dosage regimens in patients with cystic fibrosis. Drug intelligence & clinical pharmacy, 1988, Volume: 22, Issue:5 Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Child; Child, Preschool; Cystic Fibrosis; Female; Gentamicins; Humans; Infant; Male; Spectrometry, Fluorescence; Tobramycin	1988
Management of Pseudomonas aeruginosa lung infection in Danish cystic fibrosis patients. Acta paediatrica Scandinavica, 1987, Volume: 76, Issue:6 Topics: Adolescent; Anti-Bacterial Agents; Cystic Fibrosis; Denmark; Female; Follow-Up Studies; Humans; Lactams; Lung Diseases; Male; Pseudomonas Infections; Respiratory Function Tests; Tobramycin	1987
Tobramycin elimination rate change from first to later doses in older cystic fibrosis patients. Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:3 Topics: Adolescent; Adult; Cystic Fibrosis; Female; Humans; Kinetics; Male; Pseudomonas Infections; Tobramycin	1987
Cumulative and acute toxicity of repeated high-dose tobramycin treatment in cystic fibrosis. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:4 Topics: Adolescent; Adult; Child; Cystic Fibrosis; Female; Hearing Loss, Sensorineural; Humans; Kidney Diseases; Labyrinth Diseases; Male; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin	1987
Tobramycin pharmacokinetics in cystic fibrosis. Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:9 Topics: Cystic Fibrosis; Humans; Tobramycin	1987
Tobramycin in patients with cystic fibrosis. Adjustment in dosing interval for effective treatment. Chest, 1987, Volume: 92, Issue:5 Topics: Acute Disease; Adolescent; Adult; Child; Chronic Disease; Cystic Fibrosis; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Lung Diseases; Male; Pseudomonas Infections; Tobramycin	1987
Variability of tobramycin pharmacokinetics in cystic fibrosis. The Pediatric infectious disease journal, 1987, Volume: 6, Issue:8 Topics: Adolescent; Adult; Analysis of Variance; Child; Cystic Fibrosis; Female; Half-Life; Humans; Male; Mathematics; Tissue Distribution; Tobramycin	1987
Acute desensitization of a patient with cystic fibrosis allergic to both beta-lactam and aminoglycoside antibiotics. The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:3 Topics: Adolescent; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cystic Fibrosis; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Skin Tests; Tobramycin	1987
Pseudomonas aeruginosa in the oral cavity and sputum of patients with cystic fibrosis. Oral surgery, oral medicine, and oral pathology, 1985, Volume: 59, Issue:6 Topics: Adolescent; Adult; Carbenicillin; Child; Child, Preschool; Cystic Fibrosis; Female; Gentamicins; Humans; Male; Mouth; Penicillin Resistance; Pseudomonas aeruginosa; Sputum; Tobramycin	1985
Aminoglycoside penetration, inactivation, and efficacy in cystic fibrosis sputum. The American review of respiratory disease, 1985, Volume: 132, Issue:4 Topics: Adolescent; Child; Cystic Fibrosis; Dialysis; Humans; Osmolar Concentration; Prohibitins; Pseudomonas aeruginosa; Sputum; Tobramycin	1985
Pharmacokinetics of tobramycin in patients with cystic fibrosis. Implications for the dosing interval. Chest, 1985, Volume: 88, Issue:2 Topics: Adolescent; Adult; Age Factors; Body Weight; Child; Chronic Disease; Cystic Fibrosis; Female; Half-Life; Humans; Kinetics; Male; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin	1985
Dosage of tobramycin in cystic fibrosis--a short report. Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2 Topics: Child; Cystic Fibrosis; Female; Half-Life; Humans; Respiratory Tract Infections; Tobramycin	1985
Evaluation of high-dose tobramycin-carbenicillin therapy in pseudomonal infections in cystic fibrosis. Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:10 Topics: Adolescent; Adult; Carbenicillin; Child; Cystic Fibrosis; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas Infections; Sputum; Tobramycin; Vital Capacity	1985