Compounds > tobramycin
Page last updated: 2024-08-23

tobramycin and Critical Illness

tobramycin has been researched along with Critical Illness in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (21.43)18.2507
2000's12 (42.86)29.6817
2010's5 (17.86)24.3611
2020's5 (17.86)2.80

Authors

AuthorsStudies
Ariza, J; Dominguez, MA; Gudiol, F; Guzmán, A; Peña, C; Pujol, M; Suarez, C; Tubau, F1
Duong, A; Marsot, A; Simard, C; Thirion, DJG; Williamson, D1
Duong, A; Marsot, A; Simard, C; Williamson, D1
Allegaert, K; Flint, RB1
de Hoop, M; de Wildt, SN; Hartman, SJF; Orriëns, LB; Poel, T; Zwaag, SM1
Cheng, Z; Li, S; Peng, Y; Wang, Y; Xie, F1
Chaaban, H; Johnson, PN; Lepa, TM; Miller, JL; Ranallo, C; Skrepnek, GH1
de Maat, MR; Mascini, EM; Möhlmann, JE; van Leeuwen, HJ; van Luin, M1
Barns, B; Block, C; Burrill, S; Chuk, AC; Fu, J; Katrych, O; Kousar, N; Lahey, T; Rickrode, G; Saeed, F; Saunders-Hao, P1
Al-Hasan, MN; Ereshefsky, BJ; Gokun, Y; Martin, CA1
Bies, R; Bigos, KL; Capitano, B; Lee, H; Rea, RS; Smith, R1
Dijksman, LM; Gerhards, MF; Oudemans-van Straaten, HM; Roos, D; Sondermeijer, BM; T de Wit, L1
Boucher, BA; Croce, MA; Czosnowski, QA; Fabian, TC; Magnotti, LJ; Swanson, JM; Wood, GC1
Attema-de Jonge, ME; Bosman, RJ; Endeman, H; Franssen, EJ; Oudemans-van Straaten, HM; van Ogtrop, ML; Zandstra, DF1
Hoffmann, A; Meier-Hellmann, A; Reimann, IR; Reinhart, K; Traut, T1
Borras-Blasco, J; Gonzalez-Delgado, M; Peris-Marti, JF; Rosique-Robles, JD1
Allaouchiche, B; Boselli, E; Breilh, D; Djabarouti, S; Gordien, JB; Guillaume, C; Rimmelé, T; Saux, MC; Xuereb, F1
Dahyot-Fizelier, C; Mimoz, O1
Bulut, T; Dongelmans, DA; Korevaar, JC; Schultz, MJ; Spronk, PE; Veelo, DP1
Bracco, D; Dubois, MJ; Eggimann, P; Landry, C1
Hammond, JM; Potgieter, PD1
Dorman, T; Lipsett, PA; Swoboda, S; Trentler, B; Zarfeshenfard, F1
Sieger, B1
Rommes, JH; van Saene, HK; Zandstra, DF1
Hoffmann, A; Meier-Hellmann, A; Pfeifer, R; Reimann, IR; Reinhart, K; Schilling, A; Stein, G; Traut, T1
Barletta, JF; Erstad, BL; Johnson, SB; Nix, DE; Nix, LC1
Geraedts, AA; Kesecioglu, J; Tytgat, GN; van der Ende, A; van der Hulst, RW; van der Voort, PH; Zandstra, DF1
Gilman, JT; Kearns, GL; Möller, JC; Raszynski, A; Reed, MD; Sussmane, JB; Wolfsdorf, J1

Reviews

2 review(s) available for tobramycin and Critical Illness

ArticleYear
Tobramycin a Priori Dosing Regimens Based on PopPK Model Simulations in Critically Ill Patients: Are They Transferable?
    Therapeutic drug monitoring, 2023, 10-01, Volume: 45, Issue:5

    Topics: Anti-Bacterial Agents; Critical Illness; Drug Monitoring; Humans; Retrospective Studies; Tobramycin

2023
[Selective decontamination of the digestive tract reduces mortality in intensive care patients].
    Nederlands tijdschrift voor geneeskunde, 1999, Mar-20, Volume: 143, Issue:12

    Topics: Amphotericin B; Bacterial Infections; Cefotaxime; Clinical Protocols; Colistin; Critical Care; Critical Illness; Cross Infection; Decontamination; Digestive System; Drug Therapy, Combination; Female; Humans; Intensive Care Units; Male; Survival Rate; Tobramycin

1999

Trials

4 trial(s) available for tobramycin and Critical Illness

ArticleYear
Reliability of mini-bronchoalveolar lavage for the measurement of epithelial lining fluid concentrations of tobramycin in critically ill patients.
    Intensive care medicine, 2007, Volume: 33, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bronchoalveolar Lavage; Chromatography, High Pressure Liquid; Critical Illness; Female; Humans; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Pneumonia, Ventilator-Associated; Prospective Studies; Reproducibility of Results; Respiratory Mucosa; Tobramycin

2007
Is there a role for selective decontamination of the digestive tract in primarily infected patients in the ICU?
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:2

    Topics: Administration, Oral; Adult; Amphotericin B; Cefotaxime; Colistin; Critical Care; Critical Illness; Cross Infection; Digestive System; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Placebos; Prospective Studies; Respiration, Artificial; Survival Rate; Tobramycin

1995
[Serum level-adjusted dosage of once-daily aminoglycoside therapy in critical illness: results of a prospective study].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1999, Volume: 34, Issue:5

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Creatinine; Critical Care; Critical Illness; Drug Administration Schedule; Drug Monitoring; Humans; Metabolic Clearance Rate; Middle Aged; Prospective Studies; Tobramycin

1999
Gut decontamination of critically ill patients reduces Helicobacter pylori acquisition by intensive care nurses.
    The Journal of hospital infection, 2001, Volume: 47, Issue:1

    Topics: Adult; Amphotericin B; Breath Tests; Colistin; Critical Care; Critical Illness; Cross Infection; Cross-Sectional Studies; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Infection Control; Infectious Disease Transmission, Patient-to-Professional; Nursing Staff, Hospital; Prevalence; Stomach Diseases; Tobramycin

2001

Other Studies

22 other study(ies) available for tobramycin and Critical Illness

ArticleYear
Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Carrier State; Critical Illness; Endemic Diseases; Female; Gastrointestinal Tract; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Pharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rectum; Risk Factors

2007
Aminoglycosides' dosing and monitoring practices in critically ill patients in Quebec hospitals.
    Journal of chemotherapy (Florence, Italy), 2022, Volume: 34, Issue:5

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Critical Illness; Drug Monitoring; Gentamicins; Hospitals; Humans; Quebec; Tobramycin

2022
Target Drug Exposure Attainment in Children: How to Get from Better to Best.
    Paediatric drugs, 2020, Volume: 22, Issue:4

    Topics: Anti-Bacterial Agents; Child; Critical Illness; Gentamicins; Humans; Infant, Newborn; Tobramycin; Vancomycin

2020
External Validation of Model-Based Dosing Guidelines for Vancomycin, Gentamicin, and Tobramycin in Critically Ill Neonates and Children: A Pragmatic Two-Center Study.
    Paediatric drugs, 2020, Volume: 22, Issue:4

    Topics: Anti-Bacterial Agents; Critical Illness; Drug Monitoring; Female; Gentamicins; Humans; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Male; Retrospective Studies; Tobramycin; Vancomycin

2020
Pharmacokinetic/pharmacodynamic evaluation of tobramycin dosing in critically ill patients: the Hartford nomogram does not fit.
    The Journal of antimicrobial chemotherapy, 2021, 08-12, Volume: 76, Issue:9

    Topics: Anti-Bacterial Agents; Critical Illness; Humans; Nomograms; Retrospective Studies; Tobramycin

2021
Detectable Concentrations of Inhaled Tobramycin in Critically Ill Children Without Cystic Fibrosis: Should Routine Monitoring Be Recommended?
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2017, Volume: 18, Issue:12

    Topics: Acute Kidney Injury; Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Critical Illness; Cystic Fibrosis; Drug Monitoring; Female; Humans; Infant; Infant, Newborn; Male; Retrospective Studies; Tobramycin

2017
Monitoring of tobramycin serum concentrations in selected critically ill patients receiving selective decontamination of the digestive tract: a retrospective evaluation.
    European journal of clinical pharmacology, 2019, Volume: 75, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Critical Illness; Decontamination; Drug Monitoring; Female; Gastrointestinal Tract; Humans; Intensive Care Units; Male; Middle Aged; Retrospective Studies; Tobramycin

2019
Variable pharmacokinetics of extended interval tobramycin or gentamicin among critically ill patients undergoing continuous venovenous hemofiltration.
    Clinical nephrology, 2015, Volume: 84, Issue:4

    Topics: Anti-Bacterial Agents; Critical Illness; Female; Gentamicins; Hemofiltration; Humans; Male; Middle Aged; Tobramycin

2015
Comparison of ß-lactam plus aminoglycoside versus ß-lactam plus fluoroquinolone empirical therapy in serious nosocomial infections due to Gram-negative bacilli.
    Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:1

    Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Cohort Studies; Critical Illness; Cross Infection; Drug Therapy, Combination; Female; Fluoroquinolones; Gentamicins; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Proportional Hazards Models; Retrospective Studies; Tobramycin; Treatment Outcome

2017
Suboptimal aminoglycoside dosing in critically ill patients.
    Therapeutic drug monitoring, 2008, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Critical Illness; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Female; Gentamicins; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Tobramycin

2008
Perioperative selective decontamination of the digestive tract (SDD) in elective colorectal surgery.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009, Volume: 13, Issue:10

    Topics: Aged; Amphotericin B; Anastomosis, Surgical; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colectomy; Colon; Critical Illness; Digestive System Surgical Procedures; Elective Surgical Procedures; Female; Humans; Infection Control; Male; Middle Aged; Polymyxin B; Postoperative Complications; Rectum; Retrospective Studies; Tobramycin

2009
Adjunctive aerosolized antibiotics for treatment of ventilator-associated pneumonia.
    Pharmacotherapy, 2009, Volume: 29, Issue:9

    Topics: Acinetobacter baumannii; Adult; Aerosols; Amikacin; Anti-Bacterial Agents; APACHE; Colistin; Critical Illness; Drug Resistance, Multiple; Female; Glasgow Coma Scale; Gram-Negative Bacteria; Humans; Male; Middle Aged; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Retrospective Studies; Tobramycin; Treatment Outcome

2009
Presence of tobramycin in blood and urine during selective decontamination of the digestive tract in critically ill patients, a prospective cohort study.
    Critical care (London, England), 2011, Volume: 15, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Biomarkers; Critical Illness; Decontamination; Female; Gastrointestinal Tract; Humans; Intestinal Absorption; Male; Middle Aged; Multiple Organ Failure; Prospective Studies; Renal Insufficiency; Tobramycin

2011
Monitoring of a single post-infusion blood sample to estimate the actual peak and trough concentration of tobramycin in critically ill patients.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2003, Volume: 54, Issue:5-6

    Topics: Anti-Bacterial Agents; APACHE; Bayes Theorem; Creatinine; Critical Care; Critical Illness; Drug Monitoring; Humans; Infusions, Intravenous; Linear Models; Retrospective Studies; Tobramycin

2003
Evaluation of once daily tobramycin dosing in critically ill patients through Bayesian simulation.
    Journal of clinical pharmacy and therapeutics, 2004, Volume: 29, Issue:1

    Topics: Anti-Bacterial Agents; Bayes Theorem; Body Weight; Critical Illness; Drug Administration Schedule; Hospital Bed Capacity, 300 to 499; Hospitals, University; Humans; Injections, Intravenous; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Tobramycin

2004
Mini-broncho-alveolar lavage: a simple and promising method for assessment of antibiotic concentration in epithelial lining fluid.
    Intensive care medicine, 2007, Volume: 33, Issue:9

    Topics: Anti-Bacterial Agents; Bronchoalveolar Lavage; Chromatography, High Pressure Liquid; Critical Illness; Humans; Infusions, Intravenous; Intensive Care Units; Pneumonia, Ventilator-Associated; Respiratory Mucosa; Tobramycin

2007
The incidence and microbial spectrum of ventilator-associated pneumonia after tracheotomy in a selective decontamination of the digestive tract-setting.
    The Journal of infection, 2008, Volume: 56, Issue:1

    Topics: Administration, Buccal; Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colistin; Critical Illness; Cross Infection; Decontamination; Enteral Nutrition; Female; Gastrointestinal Tract; Humans; Incidence; Intensive Care Units; Male; Methicillin; Microbial Sensitivity Tests; Middle Aged; Netherlands; Pneumonia, Ventilator-Associated; Retrospective Studies; Risk Factors; Staphylococcus aureus; Tobramycin; Tracheotomy

2008
Pharmacokinetic variability of extended interval tobramycin in burn patients.
    Burns : journal of the International Society for Burn Injuries, 2008, Volume: 34, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Burns; Creatinine; Critical Care; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Middle Aged; Prospective Studies; Pseudomonas Infections; Tobramycin; Treatment Outcome; Wound Infection

2008
Impact of altered aminoglycoside volume of distribution on the adequacy of a three milligram per kilogram loading dose. Critical Care Research Group.
    Surgery, 1998, Volume: 124, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Infections; Critical Illness; Dose-Response Relationship, Drug; Female; Gentamicins; Gram-Negative Bacteria; Humans; Intensive Care Units; Male; Middle Aged; Tobramycin

1998
Meropenem monotherapy as empiric treatment of nosocomial lower respiratory tract infection.
    Critical care medicine, 1998, Volume: 26, Issue:8

    Topics: Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Critical Illness; Cross Infection; Drug Therapy, Combination; Humans; Meropenem; Pneumonia, Bacterial; Severity of Illness Index; Thienamycins; Tobramycin; Treatment Outcome

1998
Population pharmacokinetics of aminoglycosides in critically ill trauma patients on once-daily regimens.
    The Journal of trauma, 2000, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Anti-Bacterial Agents; Body Weight; Creatinine; Critical Illness; Drug Administration Schedule; Drug Monitoring; Gentamicins; Humans; Metabolic Clearance Rate; Middle Aged; Multiple Trauma; Nonlinear Dynamics; Prospective Studies; Time Factors; Tissue Distribution; Tobramycin

2000
Effect of extracorporeal membrane oxygenation on tobramycin pharmacokinetics in sheep.
    Critical care medicine, 1992, Volume: 20, Issue:10

    Topics: Animals; Critical Illness; Disease Models, Animal; Drug Monitoring; Evaluation Studies as Topic; Extracorporeal Membrane Oxygenation; Infusions, Intravenous; Least-Squares Analysis; Metabolic Clearance Rate; Prospective Studies; Sheep; Tissue Distribution; Tobramycin

1992