tobramycin has been researched along with Chronic Disease in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (24.36) | 18.7374 |
| 1990's | 9 (11.54) | 18.2507 |
| 2000's | 22 (28.21) | 29.6817 |
| 2010's | 25 (32.05) | 24.3611 |
| 2020's | 3 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Burns, JL; Dudley, MN; Griffith, DC; King, P; Lomovskaya, O | 1 |
| Diakov, L; Lashev, L; Pashov, D | 1 |
| Boersma, WG; Bronsveld, I; Heijerman, H; Terpstra, LC; van der Geest, D | 1 |
| Bergström, CAS; Friberg, LE; Kukavica-Ibrulj, I; Levesque, RC; Sou, T | 1 |
| Fernández-Trujillo, L; Morales, EI; Sangiovanni, S | 1 |
| Debonnett, L; Gunda, P; Hamed, K; Panguluri, S | 1 |
| Bartezaghi, M; Blasi, F; Carnovale, V; Cimino, G; Lucidi, V; Messore, B; Muscianisi, E; Porpiglia, PA; Salvatore, D | 1 |
| Alberghina, F; Andreacchio, A; Canavese, F; Cravino, M; De Rosa, V; Paonessa, M | 1 |
| Alkadri, J; Mostofian, F; Radhakrishnan, D; Tang, K; Thampi, N | 1 |
| Cantón, R; Girón, RM; Lamas, A; Máiz, L; Mensa, J; Olveira, C; Pastor, D; Quintana, E | 1 |
| Mathew, JL; Ratjen, F; Stanojevic, S; Taylor, L; Waters, V | 1 |
| Pierart, F | 1 |
| Corona, PS; Espinal, L; Flores, X; Larrosa, N; Pigrau, C; Rodríguez-Pardo, D | 1 |
| Atkins, BL; Dudareva, M; Ferguson, JY; McNally, MA; Riley, ND; Stubbs, D | 1 |
| Aaron, SD; Bell, SC; Conrad, D; Dudley, MN; Fischer, R; Flume, PA; Geller, DE; Kerem, E; Loutit, JS; Morgan, EE; Smyth, AR; Stuart Elborn, J; VanDevanter, DR | 1 |
| Daines, CL; Farquharson, R; Higuchi, K; Schechter, MS; Trueman, D | 1 |
| Aptel, F; Boisset, S; Bron, AM; Chiquet, C; Creuzot-Garcher, C; Pechinot, A | 1 |
| Kotsimbos, T; Langan, KM; Peleg, AY | 1 |
| Bresnik, M; Clancy, JP; Derchak, PA; Flume, PA; Lewis, SA; Ramsey, BW; Retsch-Bogart, GZ; Tullis, DE | 1 |
| Kim, SY; Lee, HS; Park, MH; Roh, EY | 1 |
| Graepler-Mainka, U; Hellwig, D; Herrmann, G; Heuer, HE; Heyder, S; Kinder, B; Köster, H; Kröger, K; Melichar, VO; Mellies, U; Paul, K; Poplawska, K; Riethmüller, J; Smaczny, C | 1 |
| Banerjee, AR; Biswas, MC; Kundu, PK; Mandal, R; Mondal, A; Sasmal, NK | 1 |
| Boni, V; Braccini, G; Braggion, C; Campana, S; Festini, F; Galici, V; Neri, AS; Taccetti, G; Trevisan, F; Zavataro, L | 1 |
| Smyth, AR | 1 |
| Li-Bland, EA; McKee, MD; Schemitsch, EH; Wild, LM | 1 |
| Abele-Horn, M; Frosch, M; Hebestreit, H; Horn, S; Oesterlein, A; Radike, K; Schoen, C; Valenza, G | 1 |
| Dudley, MN; Griffith, DC; Lomovskaya, O; Sabet, M; Tarazi, Z; Tsivkovskii, R | 1 |
| Latremouille-Viau, D; Sawicki, GS; Shi, L; Signorovitch, JE; von Wartburg, M; Wu, EQ; Zhang, J | 1 |
| Ballmann, M; Geller, DE; Smyth, A | 1 |
| Angyalosi, G; Balp, MM; Capkun-Niggli, G; Doering, G; Higashi, K; Jansen, JP; Littlewood, KJ; Tiddens, HA | 1 |
| Adams, S; Ericson, DA; Gerard, C; Kalish, LA; Uluer, AZ; Waltz, DA | 1 |
| Gallagher, CG; Govan, JR; Hodson, ME | 1 |
| Brebach, GT; Gitelis, S | 1 |
| Tiddens, H | 1 |
| Akduman, L; Lee, DH; Oz, O; Smetana, SM | 1 |
| Alió, JL; Ferrer, C; Montero, J; Rodríguez, A; Ruiz-Moreno, JM | 1 |
| Higashiyama, Y; Hirakata, Y; Kohno, S; Miyazaki, Y; Morinaga, Y; Nakamura, S; Ohno, H; Tashiro, T; Yanagihara, K | 1 |
| Huffman, GR; Morshed, S; Ries, MD | 1 |
| Bossuyt, X; Godding, V; Leal, T; Lebecque, P; Reychler, G; Zylberberg, K | 1 |
| Adeboyeku, D; Hodson, ME; Scott, S | 1 |
| Alvarez, FG; Amorena, B; García-Alvarez, F; García-Alvarez, I; Grasa, JM; Laclériga, A; Monzón, M; Navarro-Zorraquino, M | 1 |
| Acerbi, D; Corrado, ME; Eichler, HG; Eichler, I; Pennini, R; Poli, G; Soliani Raschini, A | 1 |
| Bartnicka, MT; Chuchalin, A; Csiszér, E; Gyurkovics, K; Kapranov, N; Mazurek, H; Monici Preti, PA; Sands, D; Varoli, G | 1 |
| Heilesen, AM; Høiby, N; Koch, C; Permin, H | 1 |
| Suzuki, K | 1 |
| Hiraga, Y; Kikuchi, K; Nakahashi, M | 1 |
| Davidson, TM; Light, M; Mitchell, M; Murphy, C; Smith, C | 1 |
| Henry, SL; Ostermann, PA; Seligson, D | 2 |
| Beaulac, C; Clément-Major, S; Hawari, J; Lagacé, J | 1 |
| Ategbo, S; Druon, D; Elian, JC; Farriaux, JP; Gottrand, F; Launay, V; Loeuille, GA; Turck, D; Vic, P | 1 |
| Ben-David, J; Brodsky, A; Fradis, M; Larboni, J; Podoshin, L; Srugo, I | 1 |
| Ben-David, J; Brodzki, A; Fradis, M; Larboni, J; Podoshin, L; Srugo, I | 1 |
| Beringer, PM | 1 |
| Beaulac, C; Lagacé, J; Sachetelli, S | 1 |
| Alper, CM; Bagger-Sjobak, D; Dohar, JE; Gulhan, M; Hebda, PA; Ozunlu, A; Swarts, JD | 1 |
| González Lama, Z; Lupiola Gómez, P; Martín Barrasa, JL; Tejedor Junco, MT | 1 |
| Desrosiers, MY; Salas-Prato, M | 1 |
| Amorena, B; García-Alvarez, F; Gracia, E; Laclériga, A; Leiva, J; Monzón, M; Oteiza, C | 1 |
| Bingen, E; Bonacorsi, S; Brahimi, N; Gérardin, M; Lebourgeois, M; Mariani-Kurkdjian, P; Munck, A; Navarro, J | 1 |
| Altin, F; Arslan, MO; Cinhüseyinoglue, F; Yalçin, E | 1 |
| Bogle, S; Caldwell, NA; Conway, SP; Etherington, C; Setchfield, N; Whitehead, A | 1 |
| Greenberg, EP; Parsek, MR; Singh, PK; Welsh, MJ | 1 |
| Friis, B | 1 |
| Eckert, P; Eichfuss, HP; Pfeiffer, M | 1 |
| Crozier, DN; Khan, SR | 1 |
| Kisch, AL | 1 |
| De Boeck, K; Eggermont, E; Smet, M | 1 |
| Alhadeff, JA; Guman-Wignot, TM; Holsclaw, DS; Kaufman, J; Schmoyer, IR | 1 |
| Bentzon, MW; Høiby, N; Jensen, T; Koch, C; Pedersen, SS; Pressler, T; Rosdahl, VT | 1 |
| Norden, CW; Shinners, E | 1 |
| Gómez, JG; Jiménez-Cruz, JF; Tormo, FB | 1 |
| Behrens, F; Rotschafer, JC; Scott, DM | 1 |
| Friis-Møller, A; Høiby, N; Koch, C; Pedersen, M; Pressler, T; Stenvang Pedersen, S | 1 |
| de Witte, J; Degener, JE; Driessen, O; Dzoljic-Danilovic, G; Hop, WC; Horrevorts, AM; Kerrebijn, KF; Michel, MF | 1 |
| Antsiferova, NG; Moroz, AF; Radkevich, SA; Vetkova, LG | 1 |
| Degener, JE; Driessen, O; Dzoljic-Danilovic, G; Hermans, J; Horrevorts, AM; Kerrebijn, KF; Michel, MF | 1 |
| Kanai, S; Natsume, H; Yamamoto, M | 1 |
6 review(s) available for tobramycin and Chronic Disease
| Article | Year |
|---|---|
Inhaled tobramycin for chronic infection with pseudomonas aeruginosa in non-cystic fibrosis bronchiectasis: A systematic review and meta-analysis.
Topics: Administration, Inhalation; Bronchiectasis; Chronic Disease; Disease Progression; Female; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tobramycin; Treatment Outcome | 2021 |
Inhaled antibiotics for the treatment of chronic bronchopulmonary Pseudomonas aeruginosa infection in cystic fibrosis: systematic review of randomised controlled trials.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Colistin; Cystic Fibrosis; Humans; Lung Diseases; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Tobramycin | 2013 |
[TOBI Podhaler for treating chronic Pseudomonas aeruginosa infection in cystic fibrosis patients].
Topics: Administration, Inhalation; Anti-Bacterial Agents; Chronic Disease; Clinical Trials as Topic; Cystic Fibrosis; Dry Powder Inhalers; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2013 |
Managing Pseudomonas aeruginosa respiratory infections in cystic fibrosis.
Topics: Administration, Inhalation; Administration, Oral; Anti-Bacterial Agents; Chronic Disease; Ciprofloxacin; Cystic Fibrosis; Drug Resistance, Fungal; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin | 2015 |
A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Load; Bayes Theorem; Biological Availability; Chronic Disease; Colistin; Cystic Fibrosis; Disease Progression; Female; Forced Expiratory Volume; Humans; Information Services; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2012 |
New approaches to optimizing antimicrobial therapy in patients with cystic fibrosis.
Topics: Acute Disease; Administration, Inhalation; Aerosols; Airway Obstruction; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chronic Disease; Cystic Fibrosis; Humans; Lung Diseases; Macrolides; Membrane Proteins; Nutritional Physiological Phenomena; Peptides; Tobramycin | 1999 |
18 trial(s) available for tobramycin and Chronic Disease
| Article | Year |
|---|---|
Treatment with inhaled antibiotics in bronchiectasis, side effects, and evaluation of the tolerance test; analysis from the BATTLE randomized controlled trial.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Bronchiectasis; Bronchodilator Agents; Chronic Disease; Humans; Tobramycin | 2023 |
A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Levofloxacin; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; Treatment Outcome; Young Adult | 2015 |
Inhaled aztreonam lysine versus inhaled tobramycin in cystic fibrosis. An economic evaluation.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cost-Benefit Analysis; Cystic Fibrosis; Female; Humans; Lung Transplantation; Male; Models, Economic; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; United States; Young Adult | 2015 |
Continuous alternating inhaled antibiotics for chronic pseudomonal infection in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Medication Therapy Management; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin; Treatment Outcome | 2016 |
A prospective, randomized clinical trial comparing an antibiotic-impregnated bioabsorbable bone substitute with standard antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis and infected nonunion.
Topics: Absorption; Adult; Aged; Anti-Bacterial Agents; Bone Cements; Bone Substitutes; Chronic Disease; Drug Implants; Female; Fractures, Ununited; Humans; Male; Middle Aged; Osteomyelitis; Prospective Studies; Tobramycin; Treatment Outcome; Young Adult | 2010 |
Inhaled amiloride and tobramycin solutions fail to eradicate Burkholderia dolosa in patients with cystic fibrosis.
Topics: Administration, Inhalation; Amiloride; Anti-Bacterial Agents; Burkholderia Infections; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Endpoint Determination; Humans; Tobramycin; Treatment Failure | 2013 |
A randomised clinical trial of nebulised tobramycin or colistin in cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Chronic Disease; Colistin; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2002 |
Open follow-up study of tobramycin nebuliser solution and colistin in patients with cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Chronic Disease; Colistin; Cross-Over Studies; Cystic Fibrosis; Female; Follow-Up Studies; Humans; Male; Pseudomonas Infections; Tobramycin | 2006 |
Clinical pharmacology study of Bramitob, a tobramycin solution for nebulization, in comparison with Tobi.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Biological Availability; Chronic Disease; Cross-Over Studies; Cystic Fibrosis; Double-Blind Method; Female; Humans; Male; Nebulizers and Vaporizers; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Therapeutic Equivalency; Tobramycin | 2007 |
A formulation of aerosolized tobramycin (Bramitob) in the treatment of patients with cystic fibrosis and Pseudomonas aeruginosa infection: a double-blind, placebo-controlled, multicenter study.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Female; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome | 2007 |
Nutritional impact of antipseudomonas intravenous antibiotic courses in cystic fibrosis.
Topics: Adolescent; Adult; Amikacin; Anthropometry; Body Composition; Ceftazidime; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Nutritional Status; Opportunistic Infections; Prospective Studies; Pseudomonas Infections; Tobramycin | 1997 |
Chronic otitis media treated topically with ciprofloxacin or tobramycin.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Double-Blind Method; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Otitis Media; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome | 1997 |
[Local treatment of purulent chronic otitis media with ciprofloxacin].
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Humans; Male; Middle Aged; Otitis Media, Suppurative; Pharmaceutical Solutions; Pseudomonas Infections; Tobramycin | 1998 |
Treatment of chronic rhinosinusitis refractory to other treatments with topical antibiotic therapy delivered by means of a large-particle nebulizer: results of a controlled trial.
Topics: Administration, Intranasal; Adult; Aerosols; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Paranasal Sinuses; Pilot Projects; Prospective Studies; Quality of Life; Rhinitis; Saline Solution, Hypertonic; Sinusitis; Tobramycin; Treatment Failure | 2001 |
N-acetylcysteine in chronic blepharitis.
Topics: Acetylcysteine; Administration, Oral; Administration, Topical; Adult; Anti-Bacterial Agents; Blepharitis; Chronic Disease; Female; Fluorophotometry; Glucocorticoids; Humans; Male; Mucins; Prednisolone; Prospective Studies; Tears; Tobramycin | 2002 |
Once-daily tobramycin in the treatment of adult patients with cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Drug Administration Schedule; Forced Expiratory Volume; Humans; Lactams; Maximal Midexpiratory Flow Rate; Middle Aged; Pseudomonas Infections; Respiratory Tract Infections; Tobramycin; Vital Capacity | 2002 |
Treatment of Pseudomonas lung infection in cystic fibrosis with piperacillin plus tobramycin versus ceftazidime monotherapy: preliminary communication.
Topics: Ceftazidime; Chronic Disease; Cystic Fibrosis; Drug Combinations; Forced Expiratory Volume; Humans; Leukocyte Count; Lung Diseases; Neutrophils; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Tobramycin; Vital Capacity | 1989 |
Immediate and prolonged clinical efficacy of ceftazidime versus ceftazidime plus tobramycin in chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Topics: Adult; Ceftazidime; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Lung Diseases; Male; Pseudomonas Infections; Random Allocation; Time Factors; Tobramycin | 1986 |
54 other study(ies) available for tobramycin and Chronic Disease
| Article | Year |
|---|---|
In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis.
Topics: Aerosols; Anti-Bacterial Agents; Bacteria; Biofilms; Chronic Disease; Ciprofloxacin; Colony Count, Microbial; Cystic Fibrosis; Humans; Levofloxacin; Lung Diseases; Microbial Sensitivity Tests; Ofloxacin; Sputum | 2010 |
[Subchronic toxicity of apramycin in pigs].
Topics: Animals; Anti-Bacterial Agents; Blood Cell Count; Body Weight; Chronic Disease; Dose-Response Relationship, Drug; Female; Hemoglobins; Male; Nebramycin; Swine; Swine Diseases; Time Factors | 1987 |
Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic
Topics: Animals; Anti-Bacterial Agents; Chronic Disease; Drug Development; Lung; Male; Models, Biological; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Respiratory Tract Infections; Tobramycin | 2020 |
Economic Evaluation of Tobramycin Inhalation Powder for the Treatment of Chronic Pulmonary Pseudomonas aeruginosa Infection in Patients with Cystic Fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Chronic Disease; Cost-Benefit Analysis; Cystic Fibrosis; Economics, Pharmaceutical; Female; Humans; Male; Middle Aged; Powders; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Young Adult | 2017 |
Treatment compliance in cystic fibrosis patients with chronic Pseudomonas aeruginosa infection treated with tobramycin inhalation powder: The FREE study.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Dry Powder Inhalers; Humans; Longitudinal Studies; Medication Adherence; Opportunistic Infections; Patient Satisfaction; Pseudomonas aeruginosa; Pseudomonas Infections; Quality of Life; Tobramycin; Young Adult | 2018 |
Tobramycin-impregnated calcium sulfate pellets for the treatment of chronic osteomyelitis in children and adolescents.
Topics: Adolescent; Anti-Bacterial Agents; Calcium Sulfate; Child; Child, Preschool; Chronic Disease; Drug Implants; Female; Follow-Up Studies; Humans; Male; Osteomyelitis; Retrospective Studies; Tobramycin; Treatment Outcome | 2019 |
A real world evaluation of the long-term efficacy of strategies to prevent chronic Pseudomonas aeruginosa pulmonary infection in children with cystic fibrosis.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Cohort Studies; Cystic Fibrosis; Female; Humans; Infant; Infant, Newborn; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Retrospective Studies; Tobramycin | 2019 |
Effectiveness of inhaled tobramycin in eradicating Pseudomonas aeruginosa in children with cystic fibrosis.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Risk Factors; Secondary Prevention; Tobramycin; Treatment Outcome | 2014 |
Antibiotic susceptibility in gram-positive chronic joint arthroplasty infections: increased aminoglycoside resistance rate in patients with prior aminoglycoside-impregnated cement spacer use.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone Cements; Chronic Disease; Drug Resistance, Bacterial; Female; Gentamicins; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Prosthesis-Related Infections; Retrospective Studies; Secondary Prevention; Tobramycin | 2014 |
The use of a biodegradable antibiotic-loaded calcium sulphate carrier containing tobramycin for the treatment of chronic osteomyelitis: a series of 195 cases.
Topics: Absorbable Implants; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Calcium Sulfate; Chronic Disease; Cohort Studies; Debridement; Drug Carriers; Female; Follow-Up Studies; Humans; Intraoperative Care; Kaplan-Meier Estimate; Male; Middle Aged; Osteomyelitis; Prospective Studies; Severity of Illness Index; Statistics, Nonparametric; Tobramycin; Treatment Outcome; Wound Healing | 2014 |
Massilia timonae as cause of chronic endophthalmitis following cataract surgery.
Topics: Aged; Anti-Bacterial Agents; Ceftazidime; Chronic Disease; DNA, Bacterial; Drug Therapy, Combination; Endophthalmitis; Eye Infections, Bacterial; Female; Gram-Negative Bacterial Infections; Humans; Intravitreal Injections; Lens Implantation, Intraocular; Microbial Sensitivity Tests; Oxalobacteraceae; Phacoemulsification; Polymerase Chain Reaction; Postoperative Complications; RNA, Ribosomal, 16S; Tobramycin; Vancomycin | 2015 |
Difference of Type 3 secretion system (T3SS) effector gene genotypes (exoU and exoS) and its implication to antibiotics resistances in isolates of Pseudomonas aeruginosa from chronic otitis media.
Topics: ADP Ribose Transferases; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Chaperonin 60; Chronic Disease; Ciprofloxacin; Drug Resistance, Bacterial; Female; Genotype; Glucosyltransferases; GTPase-Activating Proteins; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Otitis Media; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Tobramycin; Type III Secretion Systems; Virulence Factors | 2017 |
Sequential Inhalational Tobramycin-Colistin-Combination in CF-Patients with Chronic P. Aeruginosa Colonization - an Observational Study.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Chronic Disease; Colistin; Cystic Fibrosis; Drug Administration Schedule; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Treatment Outcome | 2016 |
Clinicobacteriological study of chronic dacryocystitis in adults.
Topics: Adult; Age Factors; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Chloramphenicol; Chronic Disease; Ciprofloxacin; Dacryocystitis; Female; Humans; Inflammation; Lacrimal Apparatus; Male; Middle Aged; Pilot Projects; Staphylococcal Infections; Tobramycin | 2008 |
The costs of treatment of early and chronic Pseudomonas aeruginosa infection in cystic fibrosis patients.
Topics: Adult; Anti-Bacterial Agents; Ceftazidime; Child, Preschool; Chronic Disease; Ciprofloxacin; Clavulanic Acids; Colistin; Cost of Illness; Cystic Fibrosis; Humans; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Thienamycins; Ticarcillin; Tobramycin | 2009 |
Minimizing the toxicity of aminoglycosides in cystic fibrosis.
Topics: Acute Kidney Injury; Aminoglycosides; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; DNA, Mitochondrial; Drug Administration Schedule; Genetic Predisposition to Disease; Gentamicins; Hearing Loss, Sensorineural; Humans; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Renal Insufficiency; Tobramycin | 2010 |
Resistance to tobramycin and colistin in isolates of Pseudomonas aeruginosa from chronically colonized patients with cystic fibrosis under antimicrobial treatment.
Topics: Adult; Anti-Bacterial Agents; Bacterial Typing Techniques; Chronic Disease; Cluster Analysis; Colistin; Cystic Fibrosis; DNA Fingerprinting; Drug Resistance, Bacterial; Female; Genotype; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2010 |
Levofloxacin reduces inflammatory cytokine levels in human bronchial epithelia cells: implications for aerosol MP-376 (levofloxacin solution for inhalation) treatment of chronic pulmonary infections.
Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents; Cell Line; Chronic Disease; Epithelial Cells; Gene Expression Profiling; Humans; Interleukin-6; Interleukin-8; Levofloxacin; Ofloxacin; Pneumonia; Tobramycin | 2011 |
Reduced mortality in cystic fibrosis patients treated with tobramycin inhalation solution.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Deoxyribonuclease I; Female; Humans; Longitudinal Studies; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin | 2012 |
Therapeutic approaches to chronic cystic fibrosis respiratory infections with available, emerging aerosolized antibiotics.
Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Tobramycin; Treatment Outcome | 2011 |
The treatment of chronic osteomyelitis with a biodegradable antibiotic-impregnated implant.
Topics: Absorbable Implants; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Calcium Sulfate; Chronic Disease; Drug Delivery Systems; Drug Implants; Female; Humans; Male; Middle Aged; Osteomyelitis; Tobramycin; Treatment Outcome; Vancomycin | 2002 |
Inhaled antibiotics.
Topics: Administration, Inhalation; Anti-Bacterial Agents; Aztreonam; Chronic Disease; Cystic Fibrosis; Humans; Nebulizers and Vaporizers; Pseudomonas Infections; Tobramycin | 2004 |
A case of infected scleral buckle with Mycobacterium chelonae associated with chronic intraocular inflammation.
Topics: Anti-Bacterial Agents; Chronic Disease; Device Removal; Dexamethasone; Drug Therapy, Combination; Eye Infections, Bacterial; Glucocorticoids; Humans; Iridocyclitis; Male; Middle Aged; Mycobacterium chelonae; Mycobacterium Infections, Nontuberculous; Prosthesis-Related Infections; Reoperation; Scleral Buckling; Scleritis; Tobramycin | 2004 |
Postoperative Corynebacterium macginleyi endophthalmitis.
Topics: Aged; Aqueous Humor; Bacterial Typing Techniques; Cataract Extraction; Chronic Disease; Corynebacterium; Corynebacterium Infections; Drug Therapy, Combination; Endophthalmitis; Eye Infections, Bacterial; Gene Amplification; Humans; Lens Implantation, Intraocular; Male; Ofloxacin; Polymerase Chain Reaction; Postoperative Complications; Tobramycin; Vancomycin; Vitreous Body | 2004 |
[Case reports of the treatment with tobramycin solution for inhalation in severe bronchiectasis patients continuous infection of Pseudomonas aeruginosa].
Topics: Administration, Inhalation; Aged; Anti-Bacterial Agents; Bronchiectasis; Bronchitis; Chronic Disease; Female; Humans; Middle Aged; Pseudomonas Infections; Respiratory Therapy; Tobramycin | 2005 |
Extended trochanteric osteotomy for 2-stage revision of infected total hip arthroplasty.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Bone Cements; Chronic Disease; Debridement; Device Removal; Female; Follow-Up Studies; Humans; Male; Middle Aged; Opportunistic Infections; Osteotomy; Postoperative Complications; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Surgical Wound Infection; Tobramycin; Wound Healing | 2005 |
Towards zero prevalence of chronic Pseudomonas aeruginosa infection in children with cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Female; Humans; Male; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tobramycin | 2006 |
Interleukin-1, interleukin-6, and interleukin-10 responses after antibiotic treatment in experimental chronic Staphylococcus aureus osteomyelitis.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Cefuroxime; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Interleukin-1; Interleukin-10; Interleukin-6; Interleukins; Male; Osteomyelitis; Rats; Rats, Wistar; Staphylococcal Infections; Tibia; Tobramycin; Vancomycin | 2006 |
Treatment of chronic pseudomonas aeruginosa infection in cystic fibrosis patients with ceftazidime and tobramycin.
Topics: Adolescent; Adult; Ceftazidime; Cephalosporins; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 1983 |
[Clinical evaluations of tobramycin in treatment of chronic complicated urinary tract infections by intravenous drip infusion administration (author's transl)].
Topics: Adult; Aged; Anti-Bacterial Agents; Chronic Disease; Drug Evaluation; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Tobramycin; Urinary Tract Infections | 1982 |
[Clinical studies on tobramycin by intravenous drip infusion for Pseudomonas aeruginosa infection in chronic respiratory diseases (author's transl)].
Topics: Adult; Aged; Anti-Bacterial Agents; Chronic Disease; Drug Evaluation; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Pseudomonas Infections; Radiography; Respiratory Tract Infections; Tobramycin | 1981 |
Management of chronic sinusitis in cystic fibrosis.
Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Clinical Protocols; Combined Modality Therapy; Cystic Fibrosis; Endoscopy; Humans; Lung Transplantation; Maxillary Sinus; Nasal Polyps; Nasal Septum; Pneumonia, Bacterial; Preoperative Care; Pseudomonas Infections; Respiratory Tract Infections; Rhinitis; Sinusitis; Sodium Chloride; Therapeutic Irrigation; Tobramycin; Turbinates | 1995 |
Local antibiotic therapy for severe open fractures. A review of 1085 consecutive cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefazolin; Chronic Disease; Drug Therapy, Combination; Extremities; Female; Fractures, Open; Humans; Male; Methylmethacrylates; Middle Aged; Osteomyelitis; Penicillins; Retrospective Studies; Tobramycin; Wound Infection | 1995 |
The role of local antibiotic therapy in the management of compound fractures.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Drug Delivery Systems; Drug Therapy, Combination; Female; Fractures, Open; Humans; Male; Middle Aged; Osteomyelitis; Retrospective Studies; Tobramycin; Wound Infection | 1993 |
Eradication of mucoid Pseudomonas aeruginosa with fluid liposome-encapsulated tobramycin in an animal model of chronic pulmonary infection.
Topics: Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chronic Disease; Colony Count, Microbial; Liposomes; Lung; Lung Diseases; Mucous Membrane; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Tissue Distribution; Tobramycin | 1996 |
Aerosolization of low phase transition temperature liposomal tobramycin as a dry powder in an animal model of chronic pulmonary infection caused by Pseudomonas aeruginosa.
Topics: Aerosols; Animals; Anti-Bacterial Agents; Chronic Disease; Disease Models, Animal; Drug Carriers; Liposomes; Lung Diseases; Powders; Pseudomonas Infections; Rats; Rats, Sprague-Dawley; Temperature; Tobramycin | 1999 |
Treatment of chronic suppurative otitis media with topical tobramycin and dexamethasone.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Auditory Threshold; Chronic Disease; Cochlea; Dexamethasone; Drug Evaluation; Ear, Middle; Evoked Potentials, Auditory; Glucocorticoids; Macaca fascicularis; Otitis Media, Suppurative; Perilymph; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Tobramycin | 2000 |
Antibacterial susceptibility patterns of Pseudomonas strains isolated from chronic canine otitis externa.
Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Chronic Disease; Dog Diseases; Dogs; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Otitis Externa; Pseudomonas; Pseudomonas Infections; Quinolones; Tobramycin | 2000 |
A simple infection model using pre-colonized implants to reproduce rat chronic Staphylococcus aureus osteomyelitis and study antibiotic treatment.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Cefuroxime; Cephalosporins; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Male; Osteomyelitis; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Tibia; Tobramycin; Vancomycin | 2001 |
Genotypic characterization of Pseudomonas aeruginosa strains recovered from patients with cystic fibrosis after initial and subsequent colonization.
Topics: Administration, Inhalation; Administration, Oral; Ceftazidime; Child; Child, Preschool; Chronic Disease; Colistin; Colony Count, Microbial; Cystic Fibrosis; DNA, Bacterial; Drug Therapy, Combination; Electrophoresis, Gel, Pulsed-Field; Female; Genotype; Humans; Imipenem; Infant; Male; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Assessment; Tobramycin | 2001 |
A component of innate immunity prevents bacterial biofilm development.
Topics: Biofilms; Chronic Disease; Conalbumin; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Immunity, Innate; Iron; Iron Chelating Agents; Lactoferrin; Pseudomonas aeruginosa; Tobramycin | 2002 |
Chemotherapy of chronic infections with mucoid Pseudomonas aeruginosa in lower airways of patients with cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbenicillin; Child; Child, Preschool; Chronic Disease; Colistin; Cystic Fibrosis; Drug Evaluation; Drug Therapy, Combination; Female; Gentamicins; Humans; Infant; Male; Pneumonia; Precipitins; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 1979 |
Effect of intraperitoneal aprotinin treatment in acute and chronic peritonitis.
Topics: Acute Disease; Animals; Aprotinin; Chronic Disease; Injections, Intraperitoneal; Jejunum; Kinetics; Male; Peritonitis; Rats; Tobramycin | 1979 |
Tobramycin in treatment of infections due to Pseudomonas aeruginosa in patients with cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Chronic Disease; Cystic Fibrosis; Female; Humans; Lung Diseases; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 1976 |
Principles of the antimicrobial therapy of head and neck infections.
Topics: Acute Disease; Antibiotics, Antitubercular; Bacterial Infections; Cephalexin; Chronic Disease; Clindamycin; Drug Combinations; Erythromycin; Gentamicins; Humans; Methods; Minocycline; Otorhinolaryngologic Diseases; Penicillins; Streptomycin; Tobramycin | 1976 |
Analysis and HPLC fractionation of urine from patients with cystic fibrosis, chronic lung diseases and normal controls.
Topics: Adolescent; Adult; Biological Assay; Carbohydrates; Chemical Fractionation; Child; Chromatography, High Pressure Liquid; Chronic Disease; Creatinine; Cystic Fibrosis; Female; Humans; Hydrogen-Ion Concentration; Lung Diseases; Male; Proteinuria; Sialic Acids; Ticarcillin; Tobramycin | 1989 |
Combined imipenem/cilastatin and tobramycin therapy of multiresistant Pseudomonas aeruginosa in cystic fibrosis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bronchopneumonia; Child; Chronic Disease; Cilastatin; Cilastatin, Imipenem Drug Combination; Cyclopropanes; Cystic Fibrosis; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipenem; Kinetics; Male; Microbial Sensitivity Tests; Penicillin Resistance; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Thienamycins; Tobramycin | 1987 |
Ciprofloxacin as therapy for experimental osteomyelitis caused by Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Bone and Bones; Chronic Disease; Ciprofloxacin; Drug Resistance, Microbial; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Rabbits; Tobramycin | 1985 |
Treatment of chronic prostatitis: intraprostatic antibiotic injections under echography control.
Topics: Amikacin; Chronic Disease; Escherichia coli Infections; Humans; Injections; Male; Prostate; Prostatitis; Time Factors; Tobramycin; Ultrasonography | 1988 |
Use of vancomycin and tobramycin polymethylmethacrylate impregnated beads in the management of chronic osteomyelitis.
Topics: Adult; Chronic Disease; Female; Fluorescent Antibody Technique; Humans; Male; Methylmethacrylates; Osteomyelitis; Spectrometry, Fluorescence; Tobramycin; Vancomycin | 1988 |
Tobramycin in patients with cystic fibrosis. Adjustment in dosing interval for effective treatment.
Topics: Acute Disease; Adolescent; Adult; Child; Chronic Disease; Cystic Fibrosis; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Lung Diseases; Male; Pseudomonas Infections; Tobramycin | 1987 |
[Effectiveness of a polyvalent corpuscular Pseudomonas aeruginosa vaccine, antibiotics and their combinations in experimental chronic Pseudomonas aeruginosa infection].
Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Bacterial Vaccines; Chronic Disease; Combined Modality Therapy; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mice; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors; Tobramycin | 1985 |
Pharmacokinetics of tobramycin in patients with cystic fibrosis. Implications for the dosing interval.
Topics: Adolescent; Adult; Age Factors; Body Weight; Child; Chronic Disease; Cystic Fibrosis; Female; Half-Life; Humans; Kinetics; Male; Pseudomonas Infections; Respiratory Tract Infections; Time Factors; Tobramycin | 1985 |
[The effectiveness of a combination of trimethoprim plus rifampicin and local injection of antibiotics into the prostate in chronic bacterial prostatitis].
Topics: Adult; Bacterial Infections; Chronic Disease; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Humans; Injections; Male; Middle Aged; Prostate; Prostatitis; Rifampin; Tobramycin; Trimethoprim | 1985 |