Page last updated: 2024-08-23

tobramycin and B cepacia Infection

tobramycin has been researched along with B cepacia Infection in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.17)18.2507
2000's11 (45.83)29.6817
2010's12 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caljon, G; Cappoen, D; Coenye, T; Cools, F; Cos, P; Delputte, P; Maes, L; Maira, BM; Martinet, W; Torfs, E; Vanhoutte, B1
Antony, VB; Carden, JL; Gaggar, A; Garcia, BA; Goodwin, DL; Leon, K; Rowe, SM; Smith, TA; Solomon, GM1
Kemper, AL; Young, DC; Zobell, JT1
Coenye, T; Messiaen, AS; Nelis, H1
LiPuma, JJ; Matukas, L; Ratjen, A; Speert, DP; Tullis, E; Waters, V; Wettlaufer, J; Yau, Y; Zlosnik, JE1
Cooper, R; Howe, R; Jenkins, R; Wootton, M1
Gilchrist, FJ; Kitt, H; Lenney, W1
Acke, M; Coenye, T; Cools, F; Cos, P; Gielis, J; Van Acker, H1
Brackman, G; Cappoen, D; Coenye, T; Cos, P; Crabbé, A; Rigole, P; Van den Driessche, F; Vanhoutte, B; Vercruysse, J; Verstraete, G; Vervaet, C1
Beaudoin, T; Klingel, M; McDonald, N; Ratjen, F; Rizvi, L; Tom, SK; Tullis, E; Waters, V; Wettlaufer, J; Yau, Y1
George, AM; Iredell, J; Middleton, PG; Treerat, P; Widmer, F1
Bertram, C; Elborn, JS; Hodson, M1
Grimwood, K; Kidd, TJ; Tweed, M1
Church, AC; Foweraker, J; Parmer, J; Sivasothy, P1
Ball, R; Brownlee, KG; Conway, SP; Denton, M; Duff, AJ; Lee, TW1
Adams, S; Ericson, DA; Gerard, C; Kalish, LA; Uluer, AZ; Waltz, DA1
Ducharme, MP; Lavigne, J; Marier, JF1
Davis, JM; Domenico, P; Gurzenda, E; Kazzaz, JA; LiPuma, JJ; Veloira, WG1
Kidd, TJ; Middleton, PG; Williams, B1
Blumer, JL; Konstan, MW; Melnick, D; Saiman, L1
Hasan, MA; Lange, CF1
Elborn, JS; McElnay, JC; Moriarty, TF; Tunney, MM1
Dodd, ME; Jones, AM; Webb, AK; Weidmann, A1
Bingen, E; Bonacorsi, S; Fitoussi, F; Lhopital, S1

Reviews

1 review(s) available for tobramycin and B cepacia Infection

ArticleYear
Mediastinal abscess after lung transplantation secondary to Burkholderia gladioli infection.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:5

    Topics: Abscess; Adult; Anti-Bacterial Agents; Burkholderia gladioli; Burkholderia Infections; Combined Modality Therapy; Cystic Fibrosis; Diagnosis, Differential; Drainage; Drug Therapy, Combination; Humans; Infusions, Intravenous; Lung Transplantation; Male; Mediastinal Diseases; Meropenem; Opportunistic Infections; Postoperative Complications; Thienamycins; Tobramycin; Tomography, X-Ray Computed

2009

Trials

6 trial(s) available for tobramycin and B cepacia Infection

ArticleYear
Pilot trial of tobramycin inhalation powder in cystic fibrosis patients with chronic Burkholderia cepacia complex infection.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2017, Volume: 16, Issue:4

    Topics: Administration, Inhalation; Adolescent; Adult; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Canada; Child; Cystic Fibrosis; Drug Monitoring; Female; Forced Expiratory Volume; Humans; Male; Pilot Projects; Respiratory Tract Infections; Sputum; Tobramycin; Treatment Outcome

2017
Can Burkholderia cepacia complex be eradicated with nebulised amiloride and TOBI?
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2010, Volume: 9, Issue:1

    Topics: Adolescent; Amiloride; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Child; Cystic Fibrosis; Drug Therapy, Combination; Humans; Nebulizers and Vaporizers; Sodium Channel Blockers; Tobramycin

2010
Inhaled amiloride and tobramycin solutions fail to eradicate Burkholderia dolosa in patients with cystic fibrosis.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2013, Volume: 12, Issue:1

    Topics: Administration, Inhalation; Amiloride; Anti-Bacterial Agents; Burkholderia Infections; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Endpoint Determination; Humans; Tobramycin; Treatment Failure

2013
The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosis.
    Chest, 2005, Volume: 128, Issue:4

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Child; Child, Preschool; Cystic Fibrosis; Disease Progression; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Meropenem; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Function Tests; Sputum; Thienamycins; Tobramycin

2005
Estimating in vivo airway surface liquid concentration in trials of inhaled antibiotics.
    Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine, 2007,Fall, Volume: 20, Issue:3

    Topics: Administration, Inhalation; Aerosols; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Computer Simulation; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Models, Biological; Nebulizers and Vaporizers; Particle Size; Pseudomonas aeruginosa; Pseudomonas Infections; Research Design; Respiratory Mechanics; Respiratory System; Sputum; Taurine; Thiadiazines; Tobramycin

2007
Sputum antibiotic concentrations: implications for treatment of cystic fibrosis lung infection.
    Pediatric pulmonology, 2007, Volume: 42, Issue:11

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Infusions, Intravenous; Microbial Sensitivity Tests; Middle Aged; Pseudomonas Infections; Sputum; Tobramycin

2007

Other Studies

17 other study(ies) available for tobramycin and B cepacia Infection

ArticleYear
Optimization and characterization of a murine lung infection model for the evaluation of novel therapeutics against Burkholderia cenocepacia.
    Journal of microbiological methods, 2017, Volume: 139

    Topics: Animals; Anti-Bacterial Agents; Burkholderia cenocepacia; Burkholderia Infections; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Liver; Lung; Mice; Mice, Inbred BALB C; Pneumonia; Respiratory Tract Infections; Spleen; Tobramycin

2017
Implementation of a successful eradication protocol for Burkholderia Cepacia complex in cystic fibrosis patients.
    BMC pulmonary medicine, 2018, Feb-14, Volume: 18, Issue:1

    Topics: Administration, Inhalation; Administration, Intravenous; Administration, Oral; Adult; Anti-Bacterial Agents; Azithromycin; Burkholderia cepacia complex; Burkholderia Infections; Ceftazidime; Clinical Protocols; Cohort Studies; Consolidation Chemotherapy; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Induction Chemotherapy; Male; Middle Aged; Pneumonia, Bacterial; Retrospective Studies; Tobramycin; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult

2018
The use of doripenem in pediatric cystic fibrosis patients in case of meropenem shortages.
    Pediatric pulmonology, 2014, Volume: 49, Issue:3

    Topics: Adolescent; Anti-Bacterial Agents; Burkholderia cenocepacia; Burkholderia Infections; Carbapenems; Child; Cystic Fibrosis; Disease Progression; Doripenem; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Pseudomonas stutzeri; Rhodospirillaceae; Thienamycins; Tobramycin; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination

2014
Investigating the role of matrix components in protection of Burkholderia cepacia complex biofilms against tobramycin.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2014, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; beta-Glucans; Biofilms; Burkholderia cepacia; Burkholderia Infections; Cystic Fibrosis; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Polysaccharides, Bacterial; Tobramycin; Virulence; Virulence Factors

2014
In vitro efficacy of high-dose tobramycin against Burkholderia cepacia complex and Stenotrophomonas maltophilia isolates from cystic fibrosis patients.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Stenotrophomonas maltophilia; Tobramycin

2015
A demonstration of the susceptibility of clinical isolates obtained from cystic fibrosis patients to manuka honey.
    Archives of microbiology, 2015, Volume: 197, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Burkholderia; Burkholderia Infections; Colistin; Cystic Fibrosis; Honey; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin

2015
Two case reports of the successful eradication of new isolates of Burkholderia cepacia complex in children with cystic fibrosis.
    BMC pharmacology & toxicology, 2016, Mar-28, Volume: 17

    Topics: Administration, Inhalation; Adolescent; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Burkholderia cepacia complex; Burkholderia Infections; Ceftazidime; Child; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; England; Female; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Penicillins; Tobramycin; Treatment Outcome

2016
The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Anti-Bacterial Agents; Biofilms; Burkholderia cepacia complex; Burkholderia Infections; Cell Death; Ciprofloxacin; Gene Expression Regulation, Bacterial; Meropenem; Microbial Sensitivity Tests; Reactive Oxygen Species; Repressor Proteins; Thienamycins; Tobramycin

2016
Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: A549 Cells; Animals; Biofilms; Burkholderia cenocepacia; Burkholderia Infections; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Econazole; Female; Humans; Mice; Mice, Inbred BALB C; Miconazole; Pneumonia, Bacterial; Tobramycin

2017
In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia.
    FEMS microbiology letters, 2008, Volume: 285, Issue:1

    Topics: Amiloride; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Interactions; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Membrane Transport Modulators; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin

2008
Implementation of European standards of care for cystic fibrosis--control and treatment of infection.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2009, Volume: 8, Issue:3

    Topics: Administration, Inhalation; Adult; Anti-Bacterial Agents; Bacterial Infections; Burkholderia cepacia; Burkholderia Infections; Child; Child, Preschool; Ciprofloxacin; Colistin; Cystic Fibrosis; Europe; Guideline Adherence; Humans; Infection Control; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Surveys and Questionnaires; Tobramycin; Young Adult

2009
Successful treatment of cepacia syndrome.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2009, Volume: 8, Issue:4

    Topics: Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Child; Cystic Fibrosis; Deoxyribonuclease I; Drug Therapy, Combination; Female; Humans; Radiography; Tobramycin

2009
Pharmacokinetics and efficacies of liposomal and conventional formulations of tobramycin after intratracheal administration in rats with pulmonary Burkholderia cepacia infection.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:12

    Topics: Animals; Burkholderia cepacia; Burkholderia Infections; Half-Life; Intubation, Intratracheal; Liposomes; Lung Diseases; Male; Rats; Rats, Sprague-Dawley; Tobramycin

2002
In vitro activity and synergy of bismuth thiols and tobramycin against Burkholderia cepacia complex.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:6

    Topics: Anti-Bacterial Agents; Bismuth; Burkholderia cepacia; Burkholderia Infections; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Sulfhydryl Compounds; Tobramycin

2003
Combination aerosol therapy to treat Burkholderia cepacia complex.
    The European respiratory journal, 2005, Volume: 26, Issue:2

    Topics: Administration, Inhalation; Adult; Amiloride; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Male; Nebulizers and Vaporizers; Sodium Channel Blockers; Tobramycin

2005
Successful treatment of cepacia syndrome with combination nebulised and intravenous antibiotic therapy.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2008, Volume: 7, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Burkholderia cepacia; Burkholderia Infections; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Meropenem; Nebulizers and Vaporizers; Syndrome; Thienamycins; Tobramycin

2008
Comparative in vitro activities of meropenem, imipenem, temocillin, piperacillin, and ceftazidime in combination with tobramycin, rifampin, or ciprofloxacin against Burkholderia cepacia isolates from patients with cystic fibrosis.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2

    Topics: Burkholderia cepacia; Burkholderia Infections; Ceftazidime; Ciprofloxacin; Cystic Fibrosis; Drug Synergism; Drug Therapy, Combination; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillins; Piperacillin; Rifampin; Thienamycins; Tobramycin

1999