tobramycin and Agricultural-Workers--Diseases

To report a case series of external ophthalmomyiasis in a region of Spain together with its common epidemiological factors and treatment.. A presentation is made of four clinical cases of patients with external ocular myiasis caused by Oestrus ovis larvae.. Ocular myiasis is a parasitic infection by larval stages of flies. It can affect the ocular globe externally and / or internally, with the former being the most frequently found condition. The organism that mainly affects the eyes is the Oestrus ovis larvae.. Ocular external myiasis is a rare condition that occasionally can occur in humans. In this case series, a common risk factor for infection is established: the previous exposure to livestock and / or agricultural activity. An adequate diagnosis and treatment could avoid the transition from external to internal form, as well as its complications.

Topics: Agricultural Workers' Diseases; Animals; Antibiotic Prophylaxis; Conjunctivitis; Dexamethasone; Diptera; Eye Infections, Parasitic; Female; Humans; Larva; Male; Middle Aged; Myiasis; Spain; Tobramycin; Young Adult

Escherichia coli serotype O147:K89:K88a,c was found to be associated with outbreaks of diarrhoea in preweaner pigs of up to 4 weeks of age on a pig unit. Resistance to apramycin, gentamicin, netilmicin, tobramycin and other antibiotics was associated with conjugative plasmids of approximately 62 kb. The presence of a gene which encoded for the aminoglycoside acetyltransferase enzyme AAC(3)IV was confirmed by DNA hybridization. Samples collected during the following 12 months revealed widespread dissemination of these resistance plasmids in non-serotypable, non-haemolytic E. coli throughout the farm. Apramycin-resistant E. coli were also isolated from a stockman and it appeared from plasmid profile analysis and antibiotic sensitivity testing that the human isolates carried the same plasmid as that carried by the porcine E. coli. Klebsiella pneumoniae, with a slightly smaller conjugative plasmid and similar resistance pattern, was isolated from the stockman's wife.

Topics: Agricultural Workers' Diseases; Animals; Cats; Diarrhea; Disease Outbreaks; DNA Probes; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Infections; Feces; Female; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Nebramycin; Nucleic Acid Hybridization; R Factors; Serotyping; Swine; Swine Diseases