tizanidine has been researched along with Xerostomia in 2 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 ng x h/mL), and the half-life (1." | 2.75 | Effects of mexiletine, a CYP1A2 inhibitor, on tizanidine pharmacokinetics and pharmacodynamics. ( Homma, M; Inomata, S; Kohda, Y; Momo, K; Osaka, Y; Tanaka, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Momo, K | 1 |
| Homma, M | 1 |
| Osaka, Y | 1 |
| Inomata, S | 1 |
| Tanaka, M | 1 |
| Kohda, Y | 1 |
| Ringwald, E | 1 |
| Campean, SJ | 1 |
| Gerstenbrand, F | 1 |
| Lorincz, A | 1 |
| Lörincz, P | 1 |
| Ludin, HP | 1 |
2 trials available for tizanidine and Xerostomia
| Article | Year |
|---|---|
Effects of mexiletine, a CYP1A2 inhibitor, on tizanidine pharmacokinetics and pharmacodynamics.
Topics: Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Area Under Curve; Blood Pressure; Chromatogr | 2010 |
[Clinical experiences with a new muscle relaxant (DS 103-282 Sandoz) (author's transl)].
Topics: Adult; Clinical Trials as Topic; Clonidine; Drug Evaluation; Drug Tolerance; Female; Humans; Male; M | 1977 |