tizanidine has been researched along with Sleep Wake Disorders in 3 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To reduce muscle tension, 34 patients of the main group received tizanidine with the modified release of active substance (sirdalud MR) in dosage one capsule (6 mg) per day." | 2.75 | [The use of sirdalud MR in patients with multiple sclerosis]. ( Batysheva, TT; Boĭko, AN; Kamchatnov, PR; Petrov, SV; Popova, NF; Zaĭtsev, KA, 2010) |
| "Tizanidine is a centrally acting alpha-2 adrenoreceptor agonist widely used in the treatment of spasticity in patients with cerebral or spinal injury, and it is causing drawsiness in some of them." | 2.71 | [Effects of tizanidine for refractory sleep disturbance in disabled children with spastic quadriplegia]. ( Cho, K; Fujieda, K; Fukuda, I; Miyamoto, A; Oka, R; Tanaka, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batysheva, TT | 1 |
| Popova, NF | 1 |
| Petrov, SV | 1 |
| Kamchatnov, PR | 1 |
| Zaĭtsev, KA | 1 |
| Boĭko, AN | 1 |
| Tanaka, H | 1 |
| Fukuda, I | 1 |
| Miyamoto, A | 1 |
| Oka, R | 1 |
| Cho, K | 1 |
| Fujieda, K | 1 |
| Ringwald, E | 1 |
| Campean, SJ | 1 |
| Gerstenbrand, F | 1 |
| Lorincz, A | 1 |
| Lörincz, P | 1 |
| Ludin, HP | 1 |
3 trials available for tizanidine and Sleep Wake Disorders
| Article | Year |
|---|---|
[The use of sirdalud MR in patients with multiple sclerosis].
Topics: Adult; Clonidine; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle W | 2010 |
[Effects of tizanidine for refractory sleep disturbance in disabled children with spastic quadriplegia].
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Child; Child, Preschool; Clonidine; Disabled Children; | 2004 |
[Clinical experiences with a new muscle relaxant (DS 103-282 Sandoz) (author's transl)].
Topics: Adult; Clinical Trials as Topic; Clonidine; Drug Evaluation; Drug Tolerance; Female; Humans; Male; M | 1977 |