tizanidine has been researched along with Pain, Postoperative in 4 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tizanidine is a centrally acting α2-agonist with muscle relaxant properties." | 6.82 | Tizanidine for the management of acute postoperative pain after inguinal hernia repair: A placebo-controlled double-blind trial. ( Akkaya, T; Caparlar, C; Kulaçoğlu, H; Mercan, U; Yazicioğlu, D, 2016) |
| "Fentanyl consumption was lower in Group SC and Group SC + T than in Group C at time periods 0-4 and 4-8 h (p < 0." | 2.87 | Ultrasound-guided bilateral superficial cervical block and preemptive single-dose oral tizanidine for post-thyroidectomy pain: a randomized-controlled double-blind study. ( Ahiskalioglu, A; Alici, HA; Ari, MA; Celik, EC; Dostbil, A; Doymus, O; Karadeniz, E; Oral Ahiskalioglu, E; Sengoz, F; Yayik, AM, 2018) |
| "Tizanidine is a centrally acting α2-agonist with muscle relaxant properties." | 2.82 | Tizanidine for the management of acute postoperative pain after inguinal hernia repair: A placebo-controlled double-blind trial. ( Akkaya, T; Caparlar, C; Kulaçoğlu, H; Mercan, U; Yazicioğlu, D, 2016) |
| "Tizanidine was given systemically to rats with experimental postoperative pain." | 1.31 | Systemic tizanidine hydrochloride (Zanaflex) partially decreases experimental postoperative pain in rats. ( Azevedo, MI; Denson, DD; Hord, AH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahiskalioglu, A | 1 |
| Yayik, AM | 1 |
| Oral Ahiskalioglu, E | 1 |
| Dostbil, A | 1 |
| Doymus, O | 1 |
| Karadeniz, E | 1 |
| Ari, MA | 1 |
| Sengoz, F | 1 |
| Alici, HA | 1 |
| Celik, EC | 1 |
| Yazicioğlu, D | 1 |
| Caparlar, C | 1 |
| Akkaya, T | 1 |
| Mercan, U | 1 |
| Kulaçoğlu, H | 1 |
| Kirmeier, R | 1 |
| Truschnegg, A | 1 |
| Payer, M | 1 |
| Acham, S | 1 |
| Schulz, K | 1 |
| Jakse, N | 1 |
| Hord, AH | 1 |
| Denson, DD | 1 |
| Azevedo, MI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Preemptive Single Dose Tizanidine and Ultrasound Guided Superficial Cervical Block on Pain After Thyroidectomy[NCT02725359] | Phase 4 | 60 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Investigation of the Effectiveness of Tizanidine on Pain After Herniorrhaphy[NCT02016443] | Phase 4 | 30 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for tizanidine and Pain, Postoperative
| Article | Year |
|---|---|
Ultrasound-guided bilateral superficial cervical block and preemptive single-dose oral tizanidine for post-thyroidectomy pain: a randomized-controlled double-blind study.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; Anestheti | 2018 |
Tizanidine for the management of acute postoperative pain after inguinal hernia repair: A placebo-controlled double-blind trial.
Topics: Acute Pain; Adult; Aged; Analgesics; Clonidine; Double-Blind Method; Female; Hernia, Inguinal; Herni | 2016 |
Tizanidine for the management of acute postoperative pain after inguinal hernia repair: A placebo-controlled double-blind trial.
Topics: Acute Pain; Adult; Aged; Analgesics; Clonidine; Double-Blind Method; Female; Hernia, Inguinal; Herni | 2016 |
Tizanidine for the management of acute postoperative pain after inguinal hernia repair: A placebo-controlled double-blind trial.
Topics: Acute Pain; Adult; Aged; Analgesics; Clonidine; Double-Blind Method; Female; Hernia, Inguinal; Herni | 2016 |
Tizanidine for the management of acute postoperative pain after inguinal hernia repair: A placebo-controlled double-blind trial.
Topics: Acute Pain; Adult; Aged; Analgesics; Clonidine; Double-Blind Method; Female; Hernia, Inguinal; Herni | 2016 |
Evaluation of a muscle relaxant on sequelae of third molar surgery: a pilot study.
Topics: Adolescent; Adult; Clonidine; Edema; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Molar | 2007 |
1 other study available for tizanidine and Pain, Postoperative
| Article | Year |
|---|---|
Systemic tizanidine hydrochloride (Zanaflex) partially decreases experimental postoperative pain in rats.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Disease Models, Animal; Male; Pain, Posto | 2001 |