tizanidine has been researched along with Muscle Cramp in 2 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
Muscle Cramp: A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tizanidine hydrochloride, an alpha(2)-adrenergic receptor agonist, is a widely used medication for the treatment of muscle spasticity." | 8.84 | Update on tizanidine for muscle spasticity and emerging indications. ( Garay, E; Malanga, G; Reiter, RD, 2008) |
| " During the 33 days before admission, she received oral tizanidine hydrochloride at 3 mg/day for leg cramps." | 7.73 | Symptomatic bradycardia probably due to tizanidine hydrochloride in a chronic hemodialysis patient. ( Abe, T; Akizawa, T; Kamimura, M; Kitabata, Y; Kobata, H; Narukawa, N; Orita, H; Shiizaki, K, 2005) |
| "Tizanidine hydrochloride, an alpha(2)-adrenergic receptor agonist, is a widely used medication for the treatment of muscle spasticity." | 4.84 | Update on tizanidine for muscle spasticity and emerging indications. ( Garay, E; Malanga, G; Reiter, RD, 2008) |
| " During the 33 days before admission, she received oral tizanidine hydrochloride at 3 mg/day for leg cramps." | 3.73 | Symptomatic bradycardia probably due to tizanidine hydrochloride in a chronic hemodialysis patient. ( Abe, T; Akizawa, T; Kamimura, M; Kitabata, Y; Kobata, H; Narukawa, N; Orita, H; Shiizaki, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malanga, G | 1 |
| Reiter, RD | 1 |
| Garay, E | 1 |
| Kitabata, Y | 1 |
| Orita, H | 1 |
| Kamimura, M | 1 |
| Shiizaki, K | 1 |
| Narukawa, N | 1 |
| Abe, T | 1 |
| Kobata, H | 1 |
| Akizawa, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of EXOPULSE Mollii Suit on Spasticity and Muscular Oxygenation in Patients With Multiple Sclerosis.[NCT05912595] | 36 participants (Anticipated) | Interventional | 2023-05-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tizanidine and Muscle Cramp
| Article | Year |
|---|---|
Update on tizanidine for muscle spasticity and emerging indications.
Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Dose-Response Relationship, Drug; Humans; Low Back | 2008 |
1 other study available for tizanidine and Muscle Cramp
| Article | Year |
|---|---|
Symptomatic bradycardia probably due to tizanidine hydrochloride in a chronic hemodialysis patient.
Topics: Aged; Bradycardia; Clonidine; Female; Humans; Kidney Failure, Chronic; Muscle Cramp; Muscle Relaxant | 2005 |