tizanidine has been researched along with Hemiplegia, Crossed in 6 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind study was carried out in 105 patients with chronic spasticity associated with hemiplegia in order to compare the efficacy and tolerability of tizanidine with that of diazepam." | 9.06 | A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia. ( Bes, A; Eyssette, M; Pierrot-Deseilligny, E; Rohmer, F; Warter, JM, 1988) |
| "To investigate the effect of tizanidine (an alpha(2) noradrenergic agonist) on transmission in the interneuronal pathway coactivated by group I and group II afferents in post-stroke patients with spastic hemiplegia." | 5.11 | Modulation of the transmission in group II heteronymous pathways by tizanidine in spastic hemiplegic patients. ( Marque, P; Maupas, E; Roques, CF; Simonetta-Moreau, M, 2004) |
| "A double-blind study was carried out in 105 patients with chronic spasticity associated with hemiplegia in order to compare the efficacy and tolerability of tizanidine with that of diazepam." | 5.06 | A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia. ( Bes, A; Eyssette, M; Pierrot-Deseilligny, E; Rohmer, F; Warter, JM, 1988) |
| "Thirty patients with old post-stroke spastic hemiparesis took part in the investigation." | 1.29 | Mechanisms of tizanidine action on spasticity. ( Georgiev, D; Milanov, I, 1994) |
| "On the spastic side a reflex with prolonged latencies and durations, as well as with decreased amplitudes and thresholds of both reflex responses was found." | 1.28 | Flexor reflex for assessment of common interneurone activity in spasticity. ( Milanov, IG, 1992) |
| "Twelve spastic patients received single oral doses of a new anti-spastic drug DS103-282 (Sandoz) 6 mg, baclofen 20 mg, and placebo on three separate days." | 1.26 | Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity. ( Hassan, N; McLellan, DL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uysal, H | 1 |
| Larsson, LE | 1 |
| Efendi, H | 1 |
| Burke, D | 1 |
| Ertekin, C | 1 |
| Maupas, E | 1 |
| Marque, P | 1 |
| Roques, CF | 1 |
| Simonetta-Moreau, M | 1 |
| Hassan, N | 1 |
| McLellan, DL | 1 |
| Milanov, I | 1 |
| Georgiev, D | 1 |
| Milanov, IG | 1 |
| Bes, A | 1 |
| Eyssette, M | 1 |
| Pierrot-Deseilligny, E | 1 |
| Rohmer, F | 1 |
| Warter, JM | 1 |
2 trials available for tizanidine and Hemiplegia, Crossed
| Article | Year |
|---|---|
Modulation of the transmission in group II heteronymous pathways by tizanidine in spastic hemiplegic patients.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Female; Hemiplegia; Humans; | 2004 |
A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Female; | 1988 |
4 other studies available for tizanidine and Hemiplegia, Crossed
| Article | Year |
|---|---|
Medium-latency reflex response of soleus elicited by peroneal nerve stimulation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Cold Temperature; Electric Stimulation; Elec | 2009 |
Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.
Topics: Adolescent; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electromyography; Female; Hemiple | 1980 |
Mechanisms of tizanidine action on spasticity.
Topics: Adult; Aged; Cerebrovascular Disorders; Clonidine; Electromyography; Female; H-Reflex; Hemiplegia; H | 1994 |
Flexor reflex for assessment of common interneurone activity in spasticity.
Topics: Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Cerebrovascular Diso | 1992 |