tizanidine has been researched along with Headache, Tension in 9 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of the modified-release formulation of tizanidine (Sirdalud) was compared with placebo in a randomized, double-blind, parallel-group study of 138 women and 47 men, aged 18 to 79 years, with a history of chronic tension-type headache (IHS categories 2." | 9.09 | Modified-release formulation of tizanidine in chronic tension-type headache. ( Färkkilä, M; Havanka, H; Hedman, C; Kataja, M; Keränen, T; Murros, K; Peltola, J; Säkö, E, 2000) |
| "The aim of this study was to clarify the changes of inhibitory interneuronal activity in patients with chronic tension-type headache with disorder of pericranial muscle after treatment, and the pharmacological mechanisms of tizanidine--an alpha 2 adrenergic agonist." | 9.07 | Effects of tizanidine administration on exteroceptive suppression of the temporalis muscle in patients with chronic tension-type headache. ( Nakashima, K; Sakuma, K; Shimoda, M; Takahashi, K; Tumura, R; Wang, Y, 1994) |
| "The efficacy of the modified-release formulation of tizanidine (Sirdalud) was compared with placebo in a randomized, double-blind, parallel-group study of 138 women and 47 men, aged 18 to 79 years, with a history of chronic tension-type headache (IHS categories 2." | 5.09 | Modified-release formulation of tizanidine in chronic tension-type headache. ( Färkkilä, M; Havanka, H; Hedman, C; Kataja, M; Keränen, T; Murros, K; Peltola, J; Säkö, E, 2000) |
| "The aim of this study was to clarify the changes of inhibitory interneuronal activity in patients with chronic tension-type headache with disorder of pericranial muscle after treatment, and the pharmacological mechanisms of tizanidine--an alpha 2 adrenergic agonist." | 5.07 | Effects of tizanidine administration on exteroceptive suppression of the temporalis muscle in patients with chronic tension-type headache. ( Nakashima, K; Sakuma, K; Shimoda, M; Takahashi, K; Tumura, R; Wang, Y, 1994) |
| "Baclofen, tizanidine and botulinum toxin A, agents used to treat disorders of muscle tone, have been studied as potential preventative treatments for migraine, tension-type headache and other related disorders." | 4.82 | Preventative treatment for migraine and tension-type headaches : do drugs having effects on muscle spasm and tone have a role? ( Freitag, FG, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thapa, AS | 1 |
| Duma, SN | 1 |
| Medvedeva, LA | 2 |
| Avakian, GN | 1 |
| Zagorul'ko, OI | 2 |
| Gnezdilov, AV | 2 |
| Esin, RG | 1 |
| Esin, OR | 1 |
| Naprienko, MV | 1 |
| Freitag, FG | 1 |
| Syrovegin, AV | 1 |
| Samoilova, NV | 1 |
| Nakashima, K | 1 |
| Tumura, R | 1 |
| Wang, Y | 1 |
| Shimoda, M | 1 |
| Sakuma, K | 1 |
| Takahashi, K | 1 |
| Filatova, EG | 1 |
| Solov'eva, AD | 1 |
| Danilov, AB | 1 |
| Murros, K | 1 |
| Kataja, M | 1 |
| Hedman, C | 1 |
| Havanka, H | 1 |
| Säkö, E | 1 |
| Färkkilä, M | 1 |
| Peltola, J | 1 |
| Keränen, T | 1 |
1 review available for tizanidine and Headache, Tension
| Article | Year |
|---|---|
Preventative treatment for migraine and tension-type headaches : do drugs having effects on muscle spasm and tone have a role?
Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; GABA Agonists; Humans; Migraine Disorders; Muscle Rel | 2003 |
5 trials available for tizanidine and Headache, Tension
| Article | Year |
|---|---|
Amitriptyline versus tizanidine in the management of tension-type headache in Nepal.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Amitriptyline; Analgesics; Clonidine; Female; | 2013 |
[A role of treatment of autonomic syndrome in patients with tension-type headache].
Topics: Administration, Oral; Adult; Analgesics, Non-Narcotic; Autonomic Nervous System; Autonomic Nervous S | 2015 |
Efficacy of neuroprotectors in patients with tension headaches.
Topics: Acupressure; Adolescent; Adult; Aged; Analgesics; Clonidine; Combined Modality Therapy; Drug Therapy | 2007 |
Effects of tizanidine administration on exteroceptive suppression of the temporalis muscle in patients with chronic tension-type headache.
Topics: Clonidine; Electric Stimulation; Humans; Muscle Contraction; Muscle Relaxants, Central; Temporal Mus | 1994 |
Modified-release formulation of tizanidine in chronic tension-type headache.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Chronic Disease; Clonidine; Delayed-Action Preparations; Dou | 2000 |
3 other studies available for tizanidine and Headache, Tension
| Article | Year |
|---|---|
[Therapeutic blockades and reflexotherapy in the complex treatment of tension headache].
Topics: Adult; Anesthetics, Local; Bupivacaine; Clonidine; Combined Modality Therapy; Female; Fluoxetine; Hu | 2010 |
[Clinical features of headache of tension type and principles of treatment].
Topics: Adult; Aged; Analgesics; Clonidine; Cyclohexanols; Female; Humans; Male; Masticatory Muscles; Middle | 2010 |
[The treatment of tension headache with sirdalud].
Topics: Adult; Chronic Disease; Clonidine; Drug Evaluation; Female; Humans; Male; Muscle Relaxants, Central; | 1997 |