Compounds > tizanidine
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tizanidine and Gastric Ulcer

tizanidine has been researched along with Gastric Ulcer in 2 studies

tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.

Research Excerpts

ExcerptRelevanceReference
"Effects of tizanidine, a centrally acting muscle relaxant, on gastric acid secretion and gastric ulcers were studied in the rat."7.66[Influence of a muscle relaxant, tizanidine, on gastric acid secretion and gastric ulcer in rats]. ( Kanaoka, R; Maeda-Hagiwara, M; Watanabe, H; Watanabe, K, 1983)
"Tizanidine, an alpha2-adrenergic receptor agonist with myospasmolytic action, is indicated for the treatment of back pain either as monotherapy or in combination with nonsteridal anti-inflammatory drugs (NSAIDs)."3.71Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects. ( Jain, NK; Kulkarni, SK; Singh, A, 2002)
"Effects of tizanidine, a centrally acting muscle relaxant, on gastric acid secretion and gastric ulcers were studied in the rat."3.66[Influence of a muscle relaxant, tizanidine, on gastric acid secretion and gastric ulcer in rats]. ( Kanaoka, R; Maeda-Hagiwara, M; Watanabe, H; Watanabe, K, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jain, NK1
Kulkarni, SK1
Singh, A1
Watanabe, K1
Watanabe, H1
Maeda-Hagiwara, M1
Kanaoka, R1

Other Studies

2 other studies available for tizanidine and Gastric Ulcer

ArticleYear
Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.
    Life sciences, 2002, May-03, Volume: 70, Issue:24

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergi

2002
[Influence of a muscle relaxant, tizanidine, on gastric acid secretion and gastric ulcer in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 82, Issue:4

    Topics: Anesthesia; Animals; Anti-Ulcer Agents; Bethanechol Compounds; Cimetidine; Clonidine; Dose-Response

1983