tizanidine has been researched along with Epileptiform Neuralgia in 5 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind study the efficacy and tolerability of tizanidine was compared with those of carbamazepine in the management of trigeminal neuralgia." | 9.06 | Tizanidine in the management of trigeminal neuralgia. ( Lataste, X; Lyberg, T; Vilming, ST, 1986) |
| "The limited efficacy of TZD in the treatment of trigeminal neuralgia may be related to the fact that it has no effect on neuronal responses to low-threshold mechanoceptive stimuli, suggesting that low-threshold mechanoceptive neurons play an important role in the pathogenesis of trigeminal neuralgia." | 6.67 | A clinical and experimental investigation of the effects of tizanidine in trigeminal neuralgia. ( Aumentado, D; Fromm, GH; Terrence, CF, 1993) |
| "In a double-blind study the efficacy and tolerability of tizanidine was compared with those of carbamazepine in the management of trigeminal neuralgia." | 5.06 | Tizanidine in the management of trigeminal neuralgia. ( Lataste, X; Lyberg, T; Vilming, ST, 1986) |
| "There is low-quality evidence that the effect of tizanidine is not significantly different than that of carbamazepine in treating trigeminal neuralgia." | 4.89 | Non-antiepileptic drugs for trigeminal neuralgia. ( Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M, 2013) |
| "The limited efficacy of TZD in the treatment of trigeminal neuralgia may be related to the fact that it has no effect on neuronal responses to low-threshold mechanoceptive stimuli, suggesting that low-threshold mechanoceptive neurons play an important role in the pathogenesis of trigeminal neuralgia." | 2.67 | A clinical and experimental investigation of the effects of tizanidine in trigeminal neuralgia. ( Aumentado, D; Fromm, GH; Terrence, CF, 1993) |
| "Tizanidine was investigated in two trials." | 2.43 | Non-antiepileptic drugs for trigeminal neuralgia. ( He, L; Wu, B; Zhou, M, 2006) |
| "Among the more common symptoms is spasticity." | 2.41 | Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis. ( Schapiro, RT, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Yang, M | 1 |
| Zhou, M | 2 |
| He, L | 2 |
| Chen, N | 1 |
| Zakrzewska, JM | 1 |
| Wu, B | 1 |
| Fromm, GH | 1 |
| Aumentado, D | 1 |
| Terrence, CF | 1 |
| Schapiro, RT | 1 |
| Vilming, ST | 1 |
| Lyberg, T | 1 |
| Lataste, X | 1 |
3 reviews available for tizanidine and Epileptiform Neuralgia
| Article | Year |
|---|---|
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans | 2013 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Ran | 2006 |
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis.
Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabin | 2001 |
2 trials available for tizanidine and Epileptiform Neuralgia
| Article | Year |
|---|---|
A clinical and experimental investigation of the effects of tizanidine in trigeminal neuralgia.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Animals; Cats; Clonidine; Double-Blind Method; Drug Resi | 1993 |
Tizanidine in the management of trigeminal neuralgia.
Topics: Aged; Analgesics; Carbamazepine; Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; M | 1986 |