tizanidine has been researched along with Electrocardiogram QT Prolonged in 2 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aimed to quantify co-administration of MQAB with interacting drugs and associated adverse drug reactions." | 1.43 | Drug safety of macrolide and quinolone antibiotics in a tertiary care hospital: administration of interacting co-medication and QT prolongation. ( Corti, N; Hoppe, L; Kovari, H; Maechler, S; Niedrig, D; Russmann, S, 2016) |
| "Tizanidine (Zanaflex) is a centrally acting imidazoline muscle relaxant that is structurally similar to clonidine (α(2)-adrenergic agonist) but not to other myorelaxants such as baclofen or benzodiazepines." | 1.38 | Tizanidine (Zanaflex): a muscle relaxant that may prolong the QT interval by blocking IKr. ( Drolet, B; Kaddar, N; Patoine, D; Pilote, S; Simard, C; Vigneault, P, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niedrig, D | 1 |
| Maechler, S | 1 |
| Hoppe, L | 1 |
| Corti, N | 1 |
| Kovari, H | 1 |
| Russmann, S | 1 |
| Kaddar, N | 1 |
| Vigneault, P | 1 |
| Pilote, S | 1 |
| Patoine, D | 1 |
| Simard, C | 1 |
| Drolet, B | 1 |
2 other studies available for tizanidine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Drug safety of macrolide and quinolone antibiotics in a tertiary care hospital: administration of interacting co-medication and QT prolongation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Atorvastatin; Clonidine; Drug Int | 2016 |
Tizanidine (Zanaflex): a muscle relaxant that may prolong the QT interval by blocking IKr.
Topics: Animals; CHO Cells; Clonidine; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Guinea Pigs | 2012 |