tizanidine has been researched along with Chemical Dependence in 2 studies
tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Neither the maximal clinical dosage of tizanidine (3 mg) nor twice that dosage (6 mg) induced any marked somatic or psychic symptoms compared with the placebo." | 2.66 | Effects of tizanidine in healthy volunteers: double-blind study compared with diazepam and a placebo. ( Igarashi, S; Yamamura, H; Yanagita, T, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zullino, DF | 1 |
| Eskenasy, AC | 1 |
| Beeson, J | 1 |
| Yanagita, T | 1 |
| Yamamura, H | 1 |
| Igarashi, S | 1 |
1 trial available for tizanidine and Chemical Dependence
| Article | Year |
|---|---|
Effects of tizanidine in healthy volunteers: double-blind study compared with diazepam and a placebo.
Topics: Adult; Blood Pressure; Clonidine; Diazepam; Double-Blind Method; Heart Rate; Humans; Male; Placebos; | 1988 |
1 other study available for tizanidine and Chemical Dependence
| Article | Year |
|---|---|
High-dose tizanidine abuse.
Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Female; Humans; Muscle Relaxants, Central; Spasm; Subst | 2003 |