Page last updated: 2024-11-05

tizanidine and Chemical Dependence

tizanidine has been researched along with Chemical Dependence in 2 studies

tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.

Research Excerpts

ExcerptRelevanceReference
" Neither the maximal clinical dosage of tizanidine (3 mg) nor twice that dosage (6 mg) induced any marked somatic or psychic symptoms compared with the placebo."2.66Effects of tizanidine in healthy volunteers: double-blind study compared with diazepam and a placebo. ( Igarashi, S; Yamamura, H; Yanagita, T, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zullino, DF1
Eskenasy, AC1
Beeson, J1
Yanagita, T1
Yamamura, H1
Igarashi, S1

Trials

1 trial available for tizanidine and Chemical Dependence

ArticleYear
Effects of tizanidine in healthy volunteers: double-blind study compared with diazepam and a placebo.
    International journal of clinical pharmacology research, 1988, Volume: 8, Issue:2

    Topics: Adult; Blood Pressure; Clonidine; Diazepam; Double-Blind Method; Heart Rate; Humans; Male; Placebos;

1988

Other Studies

1 other study available for tizanidine and Chemical Dependence

ArticleYear
High-dose tizanidine abuse.
    Psychopharmacology bulletin, 2003,Summer, Volume: 37, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Female; Humans; Muscle Relaxants, Central; Spasm; Subst

2003